FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9609, 277 aa
  1>>>pF1KE9609 277 - 277 aa - 277 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.0996+/-0.000452; mu= -1.1254+/- 0.028
 mean_var=250.5892+/-50.334, 0's: 0 Z-trim(118.5): 23  B-trim: 27 in 1/55
 Lambda= 0.081020
 statistics sampled from 31408 (31431) to 31408 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.369), width:  16
 Scan time:  7.560

The best scores are:                                      opt bits E(85289)
NP_127490 (OMIM: 609177) ZW10 interactor isoform a ( 277) 1753 217.6 2.1e-56
NP_008988 (OMIM: 609177) ZW10 interactor isoform a ( 277) 1753 217.6 2.1e-56
XP_016871094 (OMIM: 609177) PREDICTED: ZW10 intera ( 261) 1288 163.2 4.7e-40
NP_001005413 (OMIM: 609177) ZW10 interactor isofor ( 230) 1072 137.9 1.7e-32


>>NP_127490 (OMIM: 609177) ZW10 interactor isoform a [Ho  (277 aa)
 initn: 1753 init1: 1753 opt: 1753  Z-score: 1133.6  bits: 217.6 E(85289): 2.1e-56
Smith-Waterman score: 1753; 99.6% identity (99.6% similar) in 277 aa overlap (1-277:1-277)

               10        20        30        40        50        60
pF1KE9 MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_127 MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_127 DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_127 MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 TQQELDGVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKP
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_127 TQQELDRVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKP
              190       200       210       220       230       240

              250       260       270       
pF1KE9 QQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
       :::::::::::::::::::::::::::::::::::::
NP_127 QQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
              250       260       270       

>>NP_008988 (OMIM: 609177) ZW10 interactor isoform a [Ho  (277 aa)
 initn: 1753 init1: 1753 opt: 1753  Z-score: 1133.6  bits: 217.6 E(85289): 2.1e-56
Smith-Waterman score: 1753; 99.6% identity (99.6% similar) in 277 aa overlap (1-277:1-277)

               10        20        30        40        50        60
pF1KE9 MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 TQQELDGVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKP
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 TQQELDRVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKP
              190       200       210       220       230       240

              250       260       270       
pF1KE9 QQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
       :::::::::::::::::::::::::::::::::::::
NP_008 QQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
              250       260       270       

>>XP_016871094 (OMIM: 609177) PREDICTED: ZW10 interactor  (261 aa)
 initn: 1286 init1: 1286 opt: 1288  Z-score: 840.2  bits: 163.2 E(85289): 4.7e-40
Smith-Waterman score: 1288; 84.7% identity (90.2% similar) in 255 aa overlap (1-255:1-247)

               10        20        30        40        50        60
pF1KE9 MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 TQQELDGVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKP
       :::::: :::::::::::::::::::::  .  .:   :. ...      .  : :... 
XP_016 TQQELDRVFQKLGNLKQQAEQERDKLQRV-SCCSLRLRLRQRIF------QMIN-PSSRL
              190       200        210       220              230  

              250       260       270       
pF1KE9 QQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
       .  .: ::   :.:.                      
XP_016 DPRSRVQETPWGETLVCPSRLLVYNLLEM        
            240       250       260         

>>NP_001005413 (OMIM: 609177) ZW10 interactor isoform b   (230 aa)
 initn: 1072 init1: 1072 opt: 1072  Z-score: 704.4  bits: 137.9 E(85289): 1.7e-32
Smith-Waterman score: 1360; 83.0% identity (83.0% similar) in 277 aa overlap (1-277:1-230)

               10        20        30        40        50        60
pF1KE9 MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
NP_001 MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAE-------
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KE9 TQQELDGVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKP
                                               ::::::::::::::::::::
NP_001 ----------------------------------------GKLLFPEAEAEAENLPDDKP
                                                   180       190   

              250       260       270       
pF1KE9 QQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
       :::::::::::::::::::::::::::::::::::::
NP_001 QQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
           200       210       220       230




277 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 06:42:06 2016 done: Sun Nov  6 06:42:07 2016
 Total Scan time:  7.560 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]