Result of FASTA (omim) for
pFN21AE9603
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9603, 207 aa
1>>>pF1KE9603 207 - 207 aa - 207 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9723+/-0.000415; mu= 6.7702+/- 0.026
mean_var=132.2396+/-25.128, 0's: 0 Z-trim(115.4): 70 B-trim: 0 in 0/57
Lambda= 0.111530
statistics sampled from 25803 (25873) to 25803 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.303), width: 16
Scan time: 6.560
The best scores are: opt bits E(85289)
NP_005314 (OMIM: 142712) histone H1t [Homo sapiens ( 207) 1233 209.3 3.7e-54
NP_005312 (OMIM: 142220) histone H1.4 [Homo sapien ( 219) 567 102.1 7e-22
NP_005316 (OMIM: 142709) histone H1.1 [Homo sapien ( 215) 558 100.7 1.9e-21
NP_005313 (OMIM: 142711) histone H1.5 [Homo sapien ( 226) 529 96.0 5e-20
NP_005310 (OMIM: 142710) histone H1.2 [Homo sapien ( 213) 523 95.0 9.3e-20
NP_005311 (OMIM: 142210) histone H1.3 [Homo sapien ( 221) 512 93.3 3.3e-19
NP_005309 (OMIM: 142708) histone H1.0 [Homo sapien ( 194) 282 56.2 4.1e-08
NP_006017 (OMIM: 602785) histone H1x [Homo sapiens ( 213) 224 46.9 2.8e-05
>>NP_005314 (OMIM: 142712) histone H1t [Homo sapiens] (207 aa)
initn: 1233 init1: 1233 opt: 1233 Z-score: 1093.3 bits: 209.3 E(85289): 3.7e-54
Smith-Waterman score: 1233; 99.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207)
10 20 30 40 50 60
pF1KE9 MSETVPAASASAGLAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 RSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKPRATTPKTVRSGRKAKGAKGKQKQK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_005 RSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKPRATTPKTVRSGRKAKGAKGKQQQK
130 140 150 160 170 180
190 200
pF1KE9 SPVKARASKSKLTQHHEVNVRKATSKK
:::::::::::::::::::::::::::
NP_005 SPVKARASKSKLTQHHEVNVRKATSKK
190 200
>>NP_005312 (OMIM: 142220) histone H1.4 [Homo sapiens] (219 aa)
initn: 670 init1: 396 opt: 567 Z-score: 513.8 bits: 102.1 E(85289): 7e-22
Smith-Waterman score: 594; 53.4% identity (74.9% similar) in 219 aa overlap (1-207:1-213)
10 20 30 40 50 60
pF1KE9 MSETVPAASASAGLAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
::::.::: :. : :: :.::..:: :: .:.::. . ::.:::.:...:.:: :
NP_005 MSETAPAAPAAP--APAEKTPVKKKARKSAG--AAKRKASGPPVSELITKAVAASKERSG
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
.::.::::::::::::::::::::::.:::::.:: ::::.::::::::::.::. .
NP_005 VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA
60 70 80 90 100 110
130 140 150 160
pF1KE9 RSKAKKSVSAKTKKLVLSRDSKSPKTA-----------KTNKRAKKPRATT-PKTVRSGR
. ::::. .::.:: . . .:.:: : :: :.:::: :.. : ..: .
NP_005 KPKAKKAGAAKAKKPAGA--AKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPK
120 130 140 150 160 170
170 180 190 200
pF1KE9 KAKGAKGKQKQKSPVKARASKSKLTQHHEVNVRKATSKK
:::.:: :. :::.::.: : : .. . .. . : ::
NP_005 KAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
180 190 200 210
>>NP_005316 (OMIM: 142709) histone H1.1 [Homo sapiens] (215 aa)
initn: 489 init1: 353 opt: 558 Z-score: 506.1 bits: 100.7 E(85289): 1.9e-21
Smith-Waterman score: 558; 53.1% identity (73.7% similar) in 213 aa overlap (1-207:1-209)
10 20 30 40 50
pF1KE9 MSETVPAASASAGLAAMEKLPTKKRGRKPAGLISASRKVP-NLSVSKLITEALSVSQERV
:::::: : :.. :: :: . :...::: .::.: : . :::.::..: : :.::
NP_005 MSETVPPAPAAS--AAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERG
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 GMSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKS
:.::.::::::::::::::::::::::..::::.:: ::::.::::::::::.::.
NP_005 GVSLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 TRSKAKKSVSAKTKKLVLSRDSK-----SPKTAKTNKRAKKPRATTPKTVRSGRKAKGAK
:. :.: :..::: :. : : :..:: :.:::: :.: :. .. .: : .:
NP_005 TKPGASK-VATKTKATGASKKLKKATGASKKSVKTPKKAKKP-AATRKSSKNPKKPKTVK
120 130 140 150 160 170
180 190 200
pF1KE9 GKQKQKSPVKARASKSKLTQHHEVNVRKATSKK
:. :::.::.: : : .. . .. . : ::
NP_005 PKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
180 190 200 210
>>NP_005313 (OMIM: 142711) histone H1.5 [Homo sapiens] (226 aa)
initn: 462 init1: 462 opt: 529 Z-score: 480.6 bits: 96.0 E(85289): 5e-20
Smith-Waterman score: 567; 51.9% identity (75.0% similar) in 216 aa overlap (1-206:1-214)
10 20 30 40 50
pF1KE9 MSETVPAASASAGLAAMEKLPTKKRG-RKPAGLISASRKVPNLSVSKLITEALSVSQERV
::::.:: .:. : .:: :.::.. .: :: .:.::. . ::.:::.:...:.::
NP_005 MSETAPAETATP--APVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERN
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 GMSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKS
:.::.::::::::.:::::::::::::.:::::.:: ::::.::::::::::.::.
NP_005 GLSLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 TRSKAKKSVSAKTKKLVLSRDSKSPKTA-------KTNKRAKKPRATTPKTV-RSGRKAK
.. ::::. .::.:: . . .:. :.: :: :.:::: :. : : .: .:::
NP_005 AKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAK
120 130 140 150 160 170
180 190 200
pF1KE9 GA-KGKQKQKSPVKARASKSKLTQHHEVNVRKATSKK
.: : :. :::.: .: : : .. . .. . : :
NP_005 AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
180 190 200 210 220
>>NP_005310 (OMIM: 142710) histone H1.2 [Homo sapiens] (213 aa)
initn: 531 init1: 379 opt: 523 Z-score: 475.7 bits: 95.0 E(85289): 9.3e-20
Smith-Waterman score: 552; 52.7% identity (73.2% similar) in 220 aa overlap (1-207:1-212)
10 20 30 40 50 60
pF1KE9 MSETVPAASASAGLAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
::::.::: :.: : :: :.::.. : :: .. ::. . ::.:::.:...:.:: :
NP_005 MSETAPAAPAAAPPA--EKAPVKKKAAKKAG--GTPRKASGPPVSELITKAVAASKERSG
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
.::.::::::::::::::::::::::.:::::.:: ::::.::::::::::.::. .
NP_005 VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA
60 70 80 90 100 110
130 140 150 160
pF1KE9 RSKAKKSVSAKTKKLVLSRDSKSPKTA-----------KTNKRAKKPRATT--PKTVRSG
. :.::. ..: :: : . .:.:: : :: :.:::: :.: :...:
NP_005 KPKVKKAGGTKPKKPVGA--AKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSP
120 130 140 150 160 170
170 180 190 200
pF1KE9 RKAKGAKGKQKQKSPVKARASKSKLTQHHEVNVRKATSKK
.::: :: :. :: :.: : : .. . :. .::. ::
NP_005 KKAKVAKPKKAAKSA--AKAVKPKAAKPKVVKPKKAAPKKK
180 190 200 210
>>NP_005311 (OMIM: 142210) histone H1.3 [Homo sapiens] (221 aa)
initn: 522 init1: 405 opt: 512 Z-score: 465.9 bits: 93.3 E(85289): 3.3e-19
Smith-Waterman score: 535; 49.1% identity (72.9% similar) in 218 aa overlap (1-207:1-215)
10 20 30 40 50 60
pF1KE9 MSETVPAASASAGLAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
::::.: : . : :: :.::...: :: ...::. . ::.:::.:...:.:: :
NP_005 MSETAPLAPTIP--APAEKTPVKKKAKK-AGATAGKRKASGPPVSELITKAVAASKERSG
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
.::.::::::::::::::::::::::.:::::.:: ::::.::::::::::.::.
NP_005 VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEG
60 70 80 90 100 110
130 140 150 160
pF1KE9 RSKAKKSVSAKTKKLV-LSRDSK------SPKTA--KTNKRAKKPR--ATTPKTVRSGRK
. ::::. .:: .: . .. : .:: . :: :..::: : : :...:..:
NP_005 KPKAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKK
120 130 140 150 160 170
170 180 190 200
pF1KE9 AKGAKGKQKQKSPVKARASKSKLTQHHEVNVRKATSKK
.: . :. :::.::.: : : .. . . . . .::
NP_005 VKTPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
180 190 200 210 220
>>NP_005309 (OMIM: 142708) histone H1.0 [Homo sapiens] (194 aa)
initn: 303 init1: 151 opt: 282 Z-score: 266.7 bits: 56.2 E(85289): 4.1e-08
Smith-Waterman score: 282; 32.6% identity (65.3% similar) in 193 aa overlap (17-207:1-188)
10 20 30 40 50 60
pF1KE9 MSETVPAASASAGLAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
: . :. . :: ...... . . : .:. :... ..:.:
NP_005 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAG
10 20 30 40
70 80 90 100 110
pF1KE9 MSLVALKKALAAAGYDVEKN-NSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKS
: ...: . . : : .: .:.::::.: ::. :.: ::.:.::::::.:.:. ::
NP_005 SSRQSIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPK-
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 TRSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKPRATTPKTVRSGRKAKGAKGKQKQ
.: : :... . ::.. . ...:: : .. .:::.:: : .. .: .. : :.
NP_005 -KSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAK--KKLAATPKKAKK
110 120 130 140 150
180 190 200
pF1KE9 KSPVKARASK-SKLTQHHEVNVRKATSKK
. :::. : :: . . :. . .: :
NP_005 PKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
160 170 180 190
>>NP_006017 (OMIM: 602785) histone H1x [Homo sapiens] (213 aa)
initn: 167 init1: 167 opt: 224 Z-score: 215.7 bits: 46.9 E(85289): 2.8e-05
Smith-Waterman score: 231; 28.4% identity (60.3% similar) in 204 aa overlap (1-202:17-207)
10 20 30 40
pF1KE9 MSETVPAASASAGLAAMEKLPTKKRGRKPAGLISASRKVPNLSV
:.. : :..::.:. :.::: : ... :. .
NP_006 MSVELEEALPVTTAEGMAKKVTKAGGSAALS-----PSKKRKN------SKKKNQPG-KY
10 20 30 40
50 60 70 80 90 100
pF1KE9 SKLITEALSVSQERVGMSLVAL-KKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGT
:.:..:.. :: : ::. . .: . .: ... . .: :.:.::.. :.:..::
NP_006 SQLVVETIRRLGERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGT
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE9 GASGSFKLSKKVIPKSTRSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKP-RATTPK
::.:::::..: . . . .. .... . . . .: .: . . ::: :. :.
NP_006 GANGSFKLNRKKLEGGGERRGAPAAATAPAPTAHKAKKAAPGAAGSRRADKKPARGQKPE
110 120 130 140 150 160
170 180 190 200
pF1KE9 TVRSGRKAKGAKGKQKQKSPVKARASKSKLTQHHEVNVRKATSKK
:: .:. ::: . :. : :. .:. . . .: :
NP_006 Q-RSHKKGAGAKKDKGGKAKKTAAAGGKKVKKAAKPSVPKVPKGRK
170 180 190 200 210
207 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:29:20 2016 done: Sun Nov 6 06:29:21 2016
Total Scan time: 6.560 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]