FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9602, 197 aa
  1>>>pF1KE9602 197 - 197 aa - 197 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.4307+/-0.000417; mu= -0.6892+/- 0.026
 mean_var=180.9964+/-35.070, 0's: 0 Z-trim(117.8): 19  B-trim: 453 in 1/56
 Lambda= 0.095332
 statistics sampled from 30117 (30131) to 30117 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.353), width:  16
 Scan time:  6.560

The best scores are:                                      opt bits E(85289)
NP_872319 (OMIM: 609394) kinetochore protein Spc24 ( 197) 1260 184.8 7.5e-47
NP_001303961 (OMIM: 609394) kinetochore protein Sp ( 170) 1014 151.0   1e-36
NP_001303962 (OMIM: 609394) kinetochore protein Sp ( 140)  910 136.6 1.8e-32
NP_001303960 (OMIM: 609394) kinetochore protein Sp ( 175)  897 134.9 7.3e-32
XP_011526004 (OMIM: 609394) PREDICTED: kinetochore ( 138)  832 125.9   3e-29
XP_005259810 (OMIM: 609394) PREDICTED: kinetochore ( 151)  565 89.2 3.6e-18


>>NP_872319 (OMIM: 609394) kinetochore protein Spc24 iso  (197 aa)
 initn: 1260 init1: 1260 opt: 1260  Z-score: 962.1  bits: 184.8 E(85289): 7.5e-47
Smith-Waterman score: 1260; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)

               10        20        30        40        50        60
pF1KE9 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL
              130       140       150       160       170       180

              190       
pF1KE9 SRKFISDYLWSLVDTEW
       :::::::::::::::::
NP_872 SRKFISDYLWSLVDTEW
              190       

>>NP_001303961 (OMIM: 609394) kinetochore protein Spc24   (170 aa)
 initn: 1014 init1: 1014 opt: 1014  Z-score: 780.1  bits: 151.0 E(85289): 1e-36
Smith-Waterman score: 1014; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)

               10        20        30        40        50        60
pF1KE9 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL
       ::::::::::::::::::::::::::::::::::::::::::                  
NP_001 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGSILFGEPF          
              130       140       150       160       170          

              190       
pF1KE9 SRKFISDYLWSLVDTEW

>>NP_001303962 (OMIM: 609394) kinetochore protein Spc24   (140 aa)
 initn: 910 init1: 910 opt: 910  Z-score: 704.1  bits: 136.6 E(85289): 1.8e-32
Smith-Waterman score: 910; 100.0% identity (100.0% similar) in 140 aa overlap (58-197:1-140)

        30        40        50        60        70        80       
pF1KE9 RRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGL
                                     ::::::::::::::::::::::::::::::
NP_001                               MEKEVAQSLLNAKEQVHQGGVELQQLEAGL
                                             10        20        30

        90       100       110       120       130       140       
pF1KE9 QEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAVYVAQLYHQVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAVYVAQLYHQVS
               40        50        60        70        80        90

       150       160       170       180       190       
pF1KE9 KIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQLSRKFISDYLWSLVDTEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQLSRKFISDYLWSLVDTEW
              100       110       120       130       140

>>NP_001303960 (OMIM: 609394) kinetochore protein Spc24   (175 aa)
 initn: 905 init1: 888 opt: 897  Z-score: 693.0  bits: 134.9 E(85289): 7.3e-32
Smith-Waterman score: 897; 97.4% identity (98.7% similar) in 151 aa overlap (1-151:1-149)

               10        20        30        40        50        60
pF1KE9 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL
       :::::::::::::::::::::::::.  .::                             
NP_001 QEKEVDEDTTVTIPSAVYVAQLYHQL--LEWPQLGNQRESTYLCQACSFTSVTGWDK   
              130       140         150       160       170        

              190       
pF1KE9 SRKFISDYLWSLVDTEW

>>XP_011526004 (OMIM: 609394) PREDICTED: kinetochore pro  (138 aa)
 initn: 832 init1: 832 opt: 832  Z-score: 646.2  bits: 125.9 E(85289): 3e-29
Smith-Waterman score: 832; 100.0% identity (100.0% similar) in 137 aa overlap (1-137:1-137)

               10        20        30        40        50        60
pF1KE9 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL
       :::::::::::::::::                                           
XP_011 QEKEVDEDTTVTIPSAVS                                          
              130                                                  

>>XP_005259810 (OMIM: 609394) PREDICTED: kinetochore pro  (151 aa)
 initn: 550 init1: 550 opt: 565  Z-score: 447.1  bits: 89.2 E(85289): 3.6e-18
Smith-Waterman score: 877; 76.6% identity (76.6% similar) in 197 aa overlap (1-197:1-151)

               10        20        30        40        50        60
pF1KE9 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
       :::::::::::                                              :::
XP_005 EVAQSLLNAKE----------------------------------------------LER
               70                                                  

              130       140       150       160       170       180
pF1KE9 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL
           80        90       100       110       120       130    

              190       
pF1KE9 SRKFISDYLWSLVDTEW
       :::::::::::::::::
XP_005 SRKFISDYLWSLVDTEW
          140       150 




197 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 06:29:58 2016 done: Sun Nov  6 06:29:59 2016
 Total Scan time:  6.560 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]