Result of FASTA (omim) for
pFN21AE9569
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9569, 387 aa
1>>>pF1KE9569 387 - 387 aa - 387 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3169+/-0.000354; mu= 17.9724+/- 0.022
mean_var=106.4311+/-24.177, 0's: 0 Z-trim(116.8): 742 B-trim: 2607 in 2/52
Lambda= 0.124320
statistics sampled from 27340 (28228) to 27340 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.331), width: 16
Scan time: 9.090
The best scores are: opt bits E(85289)
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387) 2633 483.0 5.3e-136
XP_011523729 (OMIM: 603691) PREDICTED: galanin rec ( 330) 2078 383.3 4.4e-106
NP_003605 (OMIM: 603692) galanin receptor type 3 [ ( 368) 1263 237.2 4.7e-62
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 834 160.2 6.6e-39
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 639 125.3 2.4e-28
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 625 122.9 1.5e-27
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 608 119.8 1.2e-26
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 608 119.9 1.3e-26
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 608 119.9 1.3e-26
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 605 119.3 1.7e-26
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269) 598 117.8 3.1e-26
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 600 118.4 3.2e-26
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 600 118.4 3.2e-26
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 599 118.2 3.5e-26
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 599 118.2 3.5e-26
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 599 118.2 3.5e-26
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 599 118.2 3.6e-26
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 599 118.2 3.6e-26
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 582 115.1 2.8e-25
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 582 115.1 3e-25
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 581 114.9 3.1e-25
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 581 114.9 3.1e-25
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 578 114.4 4.6e-25
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 578 114.4 4.6e-25
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 578 114.4 4.6e-25
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 578 114.4 4.6e-25
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 578 114.4 4.7e-25
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 578 114.4 4.7e-25
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 578 114.4 4.7e-25
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 578 114.4 4.8e-25
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 577 114.2 5.6e-25
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 577 114.2 5.6e-25
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 577 114.2 5.6e-25
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 577 114.2 5.6e-25
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 577 114.2 5.6e-25
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 577 114.2 5.6e-25
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 577 114.2 5.6e-25
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 574 113.6 7.6e-25
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 565 112.1 2.4e-24
XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 560 111.1 4.1e-24
XP_016866392 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 560 111.1 4.1e-24
XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 560 111.1 4.1e-24
XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 560 111.1 4.1e-24
XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 560 111.1 4.1e-24
XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 560 111.1 4.1e-24
XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 560 111.1 4.1e-24
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 548 109.0 1.9e-23
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 548 109.0 1.9e-23
NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 543 108.0 3.1e-23
NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 543 108.0 3.1e-23
>>NP_003848 (OMIM: 603691) galanin receptor type 2 [Homo (387 aa)
initn: 2633 init1: 2633 opt: 2633 Z-score: 2562.7 bits: 483.0 E(85289): 5.3e-136
Smith-Waterman score: 2633; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387)
10 20 30 40 50 60
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 NLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 LDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 APRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 APRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 VAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 KGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQ
310 320 330 340 350 360
370 380
pF1KE9 PCILEPCPGPSWQGPKAGDSILTVDVA
:::::::::::::::::::::::::::
NP_003 PCILEPCPGPSWQGPKAGDSILTVDVA
370 380
>>XP_011523729 (OMIM: 603691) PREDICTED: galanin recepto (330 aa)
initn: 2078 init1: 2078 opt: 2078 Z-score: 2025.6 bits: 383.3 E(85289): 4.4e-106
Smith-Waterman score: 2078; 100.0% identity (100.0% similar) in 305 aa overlap (83-387:26-330)
60 70 80 90 100 110
pF1KE9 GGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHAS
::::::::::::::::::::::::::::::
XP_011 MEPKTEPDTIDAQYIGLNWRENVQWATIYTLDGWVFGSLLCKAVHFLIFLTMHAS
10 20 30 40 50
120 130 140 150 160 170
pF1KE9 SFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANL
60 70 80 90 100 110
180 190 200 210 220 230
pF1KE9 TVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKR
120 130 140 150 160 170
240 250 260 270 280 290
pF1KE9 KVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVY
180 190 200 210 220 230
300 310 320 330 340 350
pF1KE9 ALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGAL
240 250 260 270 280 290
360 370 380
pF1KE9 RPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
:::::::::::::::::::::::::::::::::::
XP_011 RPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
300 310 320 330
>>NP_003605 (OMIM: 603692) galanin receptor type 3 [Homo (368 aa)
initn: 1290 init1: 801 opt: 1263 Z-score: 1235.0 bits: 237.2 E(85289): 4.7e-62
Smith-Waterman score: 1263; 59.2% identity (77.1% similar) in 341 aa overlap (25-356:17-353)
10 20 30 40 50
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAV---
:: ::..::::::.::::: :::::::. : ..
NP_003 MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQE
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 --STTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFT
:::.::::::.:::::::::::::::::::::.:.::.:.:::::.::.:::.:::::
NP_003 PGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 LAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVC
:::::.:::::.:.::.:: ::::::: ::.::.: :. :::.:::::: . . : .:
NP_003 LAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 HPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPV--AAGSGARRAKRK
::: ::::.:. ::. .::::: :..:.:.::::.:: :: :. ::. . ::: .
NP_003 VPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 VTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYA
. : .: ::::. ::: :::::::: :.:.: .. :::: :. :: ..:::::.::.:::
NP_003 AGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LVSKHFRKGFRTI--CAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGA
:.:.::: :: . :. . :: :: :. : . : :. :: :.:.
NP_003 LASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLL----AGGG
300 310 320 330 340
360 370 380
pF1KE9 LRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
: :
NP_003 QGPEPREGPVHGGEAARGPE
350 360
>>NP_001471 (OMIM: 600377) galanin receptor type 1 [Homo (349 aa)
initn: 715 init1: 379 opt: 834 Z-score: 819.4 bits: 160.2 E(85289): 6.6e-39
Smith-Waterman score: 834; 42.5% identity (75.1% similar) in 301 aa overlap (12-306:20-317)
10 20 30 40 50
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLR
: . : : : .. ..:.::: .:..::.::..:: :
NP_001 MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLAR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 G--GQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMH
. :. ::::::::::..::: ..: :.:::::.:.: ::.:...:: .:... ..:
NP_001 SKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSML
70 80 90 100 110 120
120 130 140 150 160
pF1KE9 ASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYR---QS
.: :::::.:.:::.:: . .: ::. :::: ..: ::.::. ...: ..:.. .
NP_001 VSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASP-VAYHQGLFHP
130 140 150 160 170
170 180 190 200 210 220
pF1KE9 QLANLTVCHPAWSAPR-RRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSG
. .: : : : :: ..:. .:::::.::::.:.. . ::..: .: . . .. :
NP_001 RASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE9 ARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSC
: .:.:... .:.:...: . :.::: . : . :: :::: :.. .:: .: ..:.::
NP_001 A--SKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE9 VNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMS
::::.::..:..:::... .
NP_001 VNPIIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
300 310 320 330 340
>>NP_001043 (OMIM: 182454) somatostatin receptor type 4 (388 aa)
initn: 434 init1: 188 opt: 639 Z-score: 629.9 bits: 125.3 E(85289): 2.4e-28
Smith-Waterman score: 642; 35.9% identity (61.8% similar) in 382 aa overlap (2-369:24-376)
10 20 30
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLV
:.:. :. .. . :: : . : . ..::. ::
NP_001 MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE9 GTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLC
: :::.::. :.:: .. ..::...:::.::: :.: ::: :. .: : :::.::
NP_001 GLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLS-VPFVASSAALRHWPFGSVLC
70 80 90 100 110
100 110 120 130 140 150
pF1KE9 KAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNA-LAAIGLIWGLSLLFS
.:: . :.: .: : :...:.:::.:. .::.. : : : : .: .: ::: .
NP_001 RAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLG-VWLASLLVT
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 GPYLSYY--RQSQLANLTVC-----HPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYART
: . : .. .. ..: :::::: .. . ::....:::::..:: :
NP_001 LPIAIFADTRPARGGQAVACNLQWPHPAWSA----VFVVYTFLLGFLLPVLAIGLCYLLI
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 LRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRAT
. . ::: :. . ::...:.::..:.:...: ::::: ... : : .:
NP_001 VGKM-RAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLF----VTSLD
240 250 260 270 280
280 290 300 310 320
pF1KE9 YALRILSHLVSYANSCVNPIVYALVSKHFRKGF-RTICAGLLGRAPGRASGRVCAAARGT
.. .: ..::::::.:::.:...: .::. : :..: : : .:
NP_001 ATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCL------------RCCLL-EG-
290 300 310 320 330
330 340 350 360 370 380
pF1KE9 HSGSVLERESSDLLH--MSEAAGALRPCPGASQPC---ILEPCPGPSWQGPKAGDSILTV
.:.. :.: : .. .:: :: :: :.: ::
NP_001 -AGGA-EEEPLDYYATALKSKGGAGCMCP--PLPCQQEALQPEPGRKRIPLTRTTTF
340 350 360 370 380
pF1KE9 DVA
>>NP_001008505 (OMIM: 600018) mu-type opioid receptor is (446 aa)
initn: 569 init1: 206 opt: 625 Z-score: 615.6 bits: 122.9 E(85289): 1.5e-27
Smith-Waterman score: 632; 30.2% identity (60.6% similar) in 378 aa overlap (4-375:57-415)
10 20 30
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFA
: :: .:. :. :. . :..
NP_001 SPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMI--------TAITIMALYS
30 40 50 60 70
40 50 60 70 80 90
pF1KE9 LIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVF
.. .:: :: ::. :..: . ..::..:.::..:: . .:::.. : . : :
NP_001 IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE9 GSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLS
:..::: : . . .: .: ::: ..:.:::.:. .:... ..:::::: : ::
NP_001 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS
140 150 160 170 180 190
160 170 180 190 200
pF1KE9 LLFSGPYL----SYYRQSQL-ANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYA
.. : . . :::... .:: ::.: . . ::.:.:....:::.. . :.
NP_001 SAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYW--ENLLKICVFIFAFIMPVLIITVCYG
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE9 RTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTR
. : ..: ..... : :..:::.:.:.:.: .:: : : .. . .: :
NP_001 LMILRL-KSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE9 ATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARG
. . ..:.:::.::..::.....:.. :: .: . . : :. .:
NP_001 FQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRD
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE9 THS-GSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
: .....: . . : . . : . : :.. ::: :::
NP_001 HPSTANTVDRTNHQCLPIPSLS-----CWALEQGCLVVY-PGP-LQGPLVRYDLPAILHS
380 390 400 410 420
NP_001 SCLRGNTAPSPSGGAFLLS
430 440
>>NP_000905 (OMIM: 600018) mu-type opioid receptor isofo (400 aa)
initn: 575 init1: 206 opt: 608 Z-score: 599.7 bits: 119.8 E(85289): 1.2e-26
Smith-Waterman score: 615; 30.6% identity (61.8% similar) in 359 aa overlap (4-356:57-400)
10 20 30
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFA
: :: .:. :. :. . :..
NP_000 SPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMI--------TAITIMALYS
30 40 50 60 70
40 50 60 70 80 90
pF1KE9 LIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVF
.. .:: :: ::. :..: . ..::..:.::..:: . .:::.. : . : :
NP_000 IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE9 GSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLS
:..::: : . . .: .: ::: ..:.:::.:. .:... ..:::::: : ::
NP_000 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS
140 150 160 170 180 190
160 170 180 190 200
pF1KE9 LLFSGPYL----SYYRQSQL-ANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYA
.. : . . :::... .:: ::.: . . ::.:.:....:::.. . :.
NP_000 SAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYW--ENLLKICVFIFAFIMPVLIITVCYG
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE9 RTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTR
. : ..: ..... : :..:::.:.:.:.: .:: : : .. . .: :
NP_000 LMILRL-KSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE9 ATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARG
. . ..:.:::.::..::.....:.. :: .: . . : :. .:
NP_000 FQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRD
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE9 THS-GSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
: .....: . .: .. :: : : :
NP_000 HPSTANTVDRTNHQLENL-EAETA--PLP
380 390 400
>>NP_001138751 (OMIM: 600018) mu-type opioid receptor is (493 aa)
initn: 575 init1: 206 opt: 608 Z-score: 598.6 bits: 119.9 E(85289): 1.3e-26
Smith-Waterman score: 615; 30.6% identity (61.8% similar) in 359 aa overlap (4-356:150-493)
10 20 30
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFA
: :: .:. :. :. . :..
NP_001 SPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMI--------TAITIMALYS
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE9 LIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVF
.. .:: :: ::. :..: . ..::..:.::..:: . .:::.. : . : :
NP_001 IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPF
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE9 GSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLS
:..::: : . . .: .: ::: ..:.:::.:. .:... ..:::::: : ::
NP_001 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS
240 250 260 270 280 290
160 170 180 190 200
pF1KE9 LLFSGPYL----SYYRQSQL-ANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYA
.. : . . :::... .:: ::.: . . ::.:.:....:::.. . :.
NP_001 SAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYW--ENLLKICVFIFAFIMPVLIITVCYG
300 310 320 330 340
210 220 230 240 250 260
pF1KE9 RTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTR
. : ..: ..... : :..:::.:.:.:.: .:: : : .. . .: :
NP_001 LMILRL-KSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT
350 360 370 380 390 400
270 280 290 300 310 320
pF1KE9 ATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARG
. . ..:.:::.::..::.....:.. :: .: . . : :. .:
NP_001 FQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRD
410 420 430 440 450 460
330 340 350 360 370 380
pF1KE9 THS-GSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
: .....: . .: .. :: : : :
NP_001 HPSTANTVDRTNHQLENL-EAETA--PLP
470 480 490
>>NP_001272453 (OMIM: 600018) mu-type opioid receptor is (493 aa)
initn: 575 init1: 206 opt: 608 Z-score: 598.6 bits: 119.9 E(85289): 1.3e-26
Smith-Waterman score: 615; 30.6% identity (61.8% similar) in 359 aa overlap (4-356:150-493)
10 20 30
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFA
: :: .:. :. :. . :..
NP_001 SPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMI--------TAITIMALYS
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE9 LIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVF
.. .:: :: ::. :..: . ..::..:.::..:: . .:::.. : . : :
NP_001 IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPF
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE9 GSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLS
:..::: : . . .: .: ::: ..:.:::.:. .:... ..:::::: : ::
NP_001 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS
240 250 260 270 280 290
160 170 180 190 200
pF1KE9 LLFSGPYL----SYYRQSQL-ANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYA
.. : . . :::... .:: ::.: . . ::.:.:....:::.. . :.
NP_001 SAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYW--ENLLKICVFIFAFIMPVLIITVCYG
300 310 320 330 340
210 220 230 240 250 260
pF1KE9 RTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTR
. : ..: ..... : :..:::.:.:.:.: .:: : : .. . .: :
NP_001 LMILRL-KSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT
350 360 370 380 390 400
270 280 290 300 310 320
pF1KE9 ATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARG
. . ..:.:::.::..::.....:.. :: .: . . : :. .:
NP_001 FQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRD
410 420 430 440 450 460
330 340 350 360 370 380
pF1KE9 THS-GSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
: .....: . .: .. :: : : :
NP_001 HPSTANTVDRTNHQLENL-EAETA--PLP
470 480 490
>>NP_001138758 (OMIM: 600018) mu-type opioid receptor is (420 aa)
initn: 569 init1: 206 opt: 605 Z-score: 596.5 bits: 119.3 E(85289): 1.7e-26
Smith-Waterman score: 612; 29.7% identity (60.4% similar) in 374 aa overlap (4-370:57-417)
10 20 30
pF1KE9 MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFA
: :: .:. :. :. . :..
NP_001 SPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMI--------TAITIMALYS
30 40 50 60 70
40 50 60 70 80 90
pF1KE9 LIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVF
.. .:: :: ::. :..: . ..::..:.::..:: . .:::.. : . : :
NP_001 IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE9 GSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLS
:..::: : . . .: .: ::: ..:.:::.:. .:... ..:::::: : ::
NP_001 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS
140 150 160 170 180 190
160 170 180 190 200
pF1KE9 LLFSGPYL----SYYRQSQL-ANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYA
.. : . . :::... .:: ::.: . . ::.:.:....:::.. . :.
NP_001 SAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYW--ENLLKICVFIFAFIMPVLIITVCYG
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE9 RTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTR
. : ..: ..... : :..:::.:.:.:.: .:: : : .. . .: :
NP_001 LMILRL-KSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETT
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE9 ATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARG
. . ..:.:::.::..::.....:.. :: .: . . : :. .:
NP_001 FQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRD
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE9 THS-GSVLERESSDL-LHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDV
: .....: . .. :... .: : : : : :
NP_001 HPSTANTVDRTNHQVELNLDCHCENAKPWP-LSYNAGQSPFPFPGRV
380 390 400 410 420
pF1KE9 A
387 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:48:26 2016 done: Sun Nov 6 09:48:27 2016
Total Scan time: 9.090 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]