Result of FASTA (omim) for
pFN21AE9565
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9565, 393 aa
1>>>pF1KE9565 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7110+/-0.00056; mu= 19.9392+/- 0.035
mean_var=94.1874+/-24.616, 0's: 0 Z-trim(107.0): 641 B-trim: 1602 in 2/50
Lambda= 0.132153
statistics sampled from 14325 (15109) to 14325 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.509), E-opt: 0.2 (0.177), width: 16
Scan time: 5.060
The best scores are: opt bits E(85289)
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 2605 508.1 1.5e-143
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 2258 441.9 1.2e-123
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 2258 441.9 1.2e-123
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 2128 417.1 3.3e-116
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 528 112.0 2.4e-24
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 528 112.0 2.4e-24
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 528 112.0 2.4e-24
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 498 106.3 1.2e-22
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 469 100.8 6e-21
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 467 100.3 6.6e-21
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 455 98.2 3.8e-20
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 441 95.5 2.5e-19
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 437 94.8 4.5e-19
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 419 91.3 4.3e-18
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 419 91.3 4.3e-18
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 419 91.3 4.3e-18
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 419 91.3 4.6e-18
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 414 90.3 8.4e-18
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 403 88.2 3.6e-17
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 403 88.3 3.8e-17
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 403 88.3 3.8e-17
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 403 88.3 3.8e-17
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 401 87.8 4.7e-17
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 401 87.9 5e-17
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 400 87.6 5.3e-17
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 400 87.7 5.8e-17
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 400 87.7 5.9e-17
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 391 85.9 1.7e-16
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 391 85.9 1.7e-16
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 391 85.9 1.7e-16
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 391 85.9 1.7e-16
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 391 85.9 1.7e-16
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 391 85.9 1.7e-16
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 390 85.8 2e-16
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 379 83.7 9e-16
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 379 83.7 9e-16
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 379 83.8 1e-15
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 374 82.6 1.6e-15
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 373 82.5 1.9e-15
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 360 80.0 1e-14
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 360 80.1 1.1e-14
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 351 78.4 3.6e-14
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 351 78.4 3.6e-14
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 351 78.4 3.6e-14
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 351 78.4 3.6e-14
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 351 78.4 3.6e-14
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 351 78.4 3.6e-14
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 351 78.4 3.6e-14
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387) 348 77.7 5.1e-14
NP_003605 (OMIM: 603692) galanin receptor type 3 [ ( 368) 346 77.3 6.5e-14
>>NP_620414 (OMIM: 607122) prokineticin receptor 1 [Homo (393 aa)
initn: 2605 init1: 2605 opt: 2605 Z-score: 2698.1 bits: 508.1 E(85289): 1.5e-143
Smith-Waterman score: 2605; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KE9 METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 DYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 DYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 GLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 YGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 YGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLH
310 320 330 340 350 360
370 380 390
pF1KE9 WKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
:::::::::::::::::::::::::::::::::
NP_620 WKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
370 380 390
>>XP_016883135 (OMIM: 244200,607123) PREDICTED: prokinet (384 aa)
initn: 2258 init1: 2258 opt: 2258 Z-score: 2340.7 bits: 441.9 E(85289): 1.2e-123
Smith-Waterman score: 2258; 87.4% identity (95.5% similar) in 382 aa overlap (12-393:3-384)
10 20 30 40 50 60
pF1KE9 METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
: : .::: .:: ::.:. :::::.:::.:.:::::.:..:::::
XP_016 MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFA
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM
::::::.::.:::::::::::.:::::.:::::::::::::::::::::::::.::::::
XP_016 AKIVIGIALAGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 DYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAT
:::::::::::::::::.::::::::::::::::::::::::::::::::.:::. :::.
XP_016 DYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTAS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 GLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIE
:::::: ::::::::::::.::::: :::::::::::::::::::::::::::::::.:
XP_016 FLIALVWMVSILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 YGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLH
:::::::::::::::::::::::::.:::::::::::::.:::::::.:.:::::.::::
XP_016 YGFTIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLH
300 310 320 330 340 350
370 380 390
pF1KE9 WKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
:. : :.::::::::.: :.:.::::::::::
XP_016 WRPSQRGSKSSADLDLRTNGVPTTEEVDCIRLK
360 370 380
>>NP_658986 (OMIM: 244200,607123) prokineticin receptor (384 aa)
initn: 2258 init1: 2258 opt: 2258 Z-score: 2340.7 bits: 441.9 E(85289): 1.2e-123
Smith-Waterman score: 2258; 87.4% identity (95.5% similar) in 382 aa overlap (12-393:3-384)
10 20 30 40 50 60
pF1KE9 METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
: : .::: .:: ::.:. :::::.:::.:.:::::.:..:::::
NP_658 MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFA
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM
::::::.::.:::::::::::.:::::.:::::::::::::::::::::::::.::::::
NP_658 AKIVIGIALAGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 DYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAT
:::::::::::::::::.::::::::::::::::::::::::::::::::.:::. :::.
NP_658 DYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTAS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 GLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIE
:::::: ::::::::::::.::::: :::::::::::::::::::::::::::::::.:
NP_658 FLIALVWMVSILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 YGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLH
:::::::::::::::::::::::::.:::::::::::::.:::::::.:.:::::.::::
NP_658 YGFTIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLH
300 310 320 330 340 350
370 380 390
pF1KE9 WKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
:. : :.::::::::.: :.:.::::::::::
NP_658 WRPSQRGSKSSADLDLRTNGVPTTEEVDCIRLK
360 370 380
>>XP_011527461 (OMIM: 244200,607123) PREDICTED: prokinet (348 aa)
initn: 2128 init1: 2128 opt: 2128 Z-score: 2207.2 bits: 417.1 E(85289): 3.3e-116
Smith-Waterman score: 2128; 90.5% identity (97.7% similar) in 348 aa overlap (46-393:1-348)
20 30 40 50 60 70
pF1KE9 STSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLV
.:::::.:..:::::::::::.::.:::::
XP_011 MDEDEDMTKTRTFFAAKIVIGIALAGIMLV
10 20 30
80 90 100 110 120 130
pF1KE9 CGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHV
::::::.:::::.:::::::::::::::::::::::::.:::::::::::::::::::::
XP_011 CGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHV
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE9 LCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAI
::.::::::::::::::::::::::::::::::::.:::. :::. :::::: :::::::
XP_011 LCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAI
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE9 PSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIEFVGPVVTMTLCYARI
:::::.::::: :::::::::::::::::::::::::::::::.::::::::::::::::
XP_011 PSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARI
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE9 SRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE9 KEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLD
::::::::::.:::::::::::::.:::::::.:.:::::.:::::. : :.:::::::
XP_011 KEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSKSSADLD
280 290 300 310 320 330
380 390
pF1KE9 LKTIGMPATEEVDCIRLK
:.: :.:.::::::::::
XP_011 LRTNGVPTTEEVDCIRLK
340
>>NP_000901 (OMIM: 162642) neuropeptide Y receptor type (381 aa)
initn: 350 init1: 212 opt: 528 Z-score: 558.2 bits: 112.0 E(85289): 2.4e-24
Smith-Waterman score: 528; 29.5% identity (65.3% similar) in 308 aa overlap (47-353:35-336)
20 30 40 50 60 70
pF1KE9 TSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLVC
: . .. .: .. ...:. .: .:.:.
NP_000 GAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLG
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE9 GIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVL
::: . : .....:..:..::..:::::..:.:: .: :: . : .. . :. : ::
NP_000 VIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE--WKMGPVL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE9 CTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIP
: : : . ... ::: .: .::.::. ::. :. ... . . .:.:.: .: :.: :
NP_000 CHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASP
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE9 SAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKS-YFLFIFGIEFVGPVVTMTLCYARI
: : ... :. . : . : . :: ... : . : : . : .: :. ... :.::
NP_000 LAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRI
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE9 SRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFV
.: .. :: ... ..: :.::. .:.:....... : :...: .. :. :.
NP_000 WSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVL-
250 260 270 280 290
320 330 340 350 360 370
pF1KE9 KEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLD
:.: : . . ::: ... : : . .... : :
NP_000 DLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFK
300 310 320 330 340 350
380 390
pF1KE9 LKTIGMPATEEVDCIRLK
NP_000 AKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>XP_005263091 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 350 init1: 212 opt: 528 Z-score: 558.2 bits: 112.0 E(85289): 2.4e-24
Smith-Waterman score: 528; 29.5% identity (65.3% similar) in 308 aa overlap (47-353:35-336)
20 30 40 50 60 70
pF1KE9 TSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLVC
: . .. .: .. ...:. .: .:.:.
XP_005 GAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLG
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE9 GIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVL
::: . : .....:..:..::..:::::..:.:: .: :: . : .. . :. : ::
XP_005 VIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE--WKMGPVL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE9 CTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIP
: : : . ... ::: .: .::.::. ::. :. ... . . .:.:.: .: :.: :
XP_005 CHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASP
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE9 SAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKS-YFLFIFGIEFVGPVVTMTLCYARI
: : ... :. . : . : . :: ... : . : : . : .: :. ... :.::
XP_005 LAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRI
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE9 SRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFV
.: .. :: ... ..: :.::. .:.:....... : :...: .. :. :.
XP_005 WSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVL-
250 260 270 280 290
320 330 340 350 360 370
pF1KE9 KEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLD
:.: : . . ::: ... : : . .... : :
XP_005 DLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFK
300 310 320 330 340 350
380 390
pF1KE9 LKTIGMPATEEVDCIRLK
XP_005 AKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>XP_005263090 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 350 init1: 212 opt: 528 Z-score: 558.2 bits: 112.0 E(85289): 2.4e-24
Smith-Waterman score: 528; 29.5% identity (65.3% similar) in 308 aa overlap (47-353:35-336)
20 30 40 50 60 70
pF1KE9 TSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLVC
: . .. .: .. ...:. .: .:.:.
XP_005 GAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLG
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE9 GIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVL
::: . : .....:..:..::..:::::..:.:: .: :: . : .. . :. : ::
XP_005 VIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE--WKMGPVL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE9 CTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIP
: : : . ... ::: .: .::.::. ::. :. ... . . .:.:.: .: :.: :
XP_005 CHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASP
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE9 SAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKS-YFLFIFGIEFVGPVVTMTLCYARI
: : ... :. . : . : . :: ... : . : : . : .: :. ... :.::
XP_005 LAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRI
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE9 SRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFV
.: .. :: ... ..: :.::. .:.:....... : :...: .. :. :.
XP_005 WSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVL-
250 260 270 280 290
320 330 340 350 360 370
pF1KE9 KEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLD
:.: : . . ::: ... : : . .... : :
XP_005 DLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFK
300 310 320 330 340 350
380 390
pF1KE9 LKTIGMPATEEVDCIRLK
XP_005 AKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>NP_004239 (OMIM: 600895) prolactin-releasing peptide r (370 aa)
initn: 414 init1: 179 opt: 498 Z-score: 527.4 bits: 106.3 E(85289): 1.2e-22
Smith-Waterman score: 498; 28.6% identity (63.4% similar) in 350 aa overlap (21-361:21-353)
10 20 30 40 50 60
pF1KE9 METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
.: .: . : . : : . : : :: ...
NP_004 MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPA-----VTPFQSLQL
10 20 30 40 50
70 80 90 100 110
pF1KE9 AKIVIGMA--LVGIMLVCG-IGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCP
.. . :. : ....: : .:: ... ...: ..:.:.::.::.:::.:: :. .: :
NP_004 VHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 FEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQ
. . : . . .: : :: : .:. :..:::. .: .::.:::...::::: :.. .
NP_004 LTLAY-AFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 TATGLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIF
.. . .:..: ..:.:.: : .. : : .. .: ..: .:. . : ..
NP_004 LSAYAVLAIWALSAVLALPAAVHTYHVEL---KPHDVRLCEEFWG-SQERQRQLYAWGLL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 GIEFVGPVVTMTLCYARISRELWFKAVPGF--QTEQIRKRLRCRRKTVLVLMCILTAYVL
. .. :.... : :.:.: .: ..::: :.. : : ::.: .:. .......
NP_004 LVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRAR-RRRTFCLLVVVVVVFAV
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 CWAPFYGFTIVRDFFPTVFVKEKHYLTAFYIVE--C--IAMSNSMINTLCFVTVKNDTVK
:: :.. :...::. : .. : :: .:. : .:::.. : . .. .... .
NP_004 CWLPLHVFNLLRDLDPHAI---DPY--AFGLVQLLCHWLAMSSACYNPFIYAWLHDSFRE
290 300 310 320 330 340
360 370 380 390
pF1KE9 YFKKIMLLHWKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
..: .:. :
NP_004 ELRK-LLVAWPRKIAPHGQNMTVSVVI
350 360 370
>>NP_001049 (OMIM: 162323) substance-P receptor isoform (407 aa)
initn: 373 init1: 183 opt: 469 Z-score: 497.0 bits: 100.8 E(85289): 6e-21
Smith-Waterman score: 469; 23.8% identity (61.8% similar) in 319 aa overlap (41-354:8-317)
20 30 40 50 60
pF1KE9 NATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFF--AAKIVIGMA
: :. . . .... : : .::. :
NP_001 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAA
10 20 30
70 80 90 100 110 120
pF1KE9 LVGIMLVCGI-GNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQ
...: .. :: . . .. .:..:..:: ...:::... .: .. : : .
NP_001 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE9 LSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVW
: .: : :.. .....: .. :.:.:::.::.:::.::.. .. .: ..:
NP_001 --WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIW
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE9 TVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVD-QQLYYKSYFLFIFGIEFVGPVV
....:.:.:..:..: .. .. : :: ...: : : . . . . :..
NP_001 VLALLLAFPQGYYSTTETM-----PSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE9 TMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIV
.. :. .. :: . .:: .... .... .::.: ... .. ....:: ::. : ..
NP_001 VIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE9 RDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKY-FKKIMLLHWKASY
. : ...: : .. . .:::..: : . . . :: . ::
NP_001 PYINPDLYLK-KFIQQVYLAIMWLAMSSTMYNPIIYCCL-NDRFRLGFKHAFRCCPFISA
280 290 300 310 320
370 380 390
pF1KE9 NGGKSSADLDLKTIGMPATEEVDCIRLK
NP_001 GDYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSS
330 340 350 360 370 380
>>NP_056542 (OMIM: 162323) substance-P receptor isoform (311 aa)
initn: 373 init1: 183 opt: 467 Z-score: 496.3 bits: 100.3 E(85289): 6.6e-21
Smith-Waterman score: 467; 23.7% identity (62.2% similar) in 312 aa overlap (41-348:8-310)
20 30 40 50 60
pF1KE9 NATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFF--AAKIVIGMA
: :. . . .... : : .::. :
NP_056 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAA
10 20 30
70 80 90 100 110 120
pF1KE9 LVGIMLVCGI-GNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQ
...: .. :: . . .. .:..:..:: ...:::... .: .. : : .
NP_056 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE9 LSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVW
: .: : :.. .....: .. :.:.:::.::.:::.::.. .. .: ..:
NP_056 --WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIW
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE9 TVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVD-QQLYYKSYFLFIFGIEFVGPVV
....:.:.:..:..: .. .. : :: ...: : : . . . . :..
NP_056 VLALLLAFPQGYYSTTETM-----PSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE9 TMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIV
.. :. .. :: . .:: .... .... .::.: ... .. ....:: ::. : ..
NP_056 VIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE9 RDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYN
. : ...: : .. . .:::..: : . . . ::
NP_056 PYINPDLYLK-KFIQQVYLAIMWLAMSSTMYNPIIYCCL-NDR
280 290 300 310
370 380 390
pF1KE9 GGKSSADLDLKTIGMPATEEVDCIRLK
393 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:00:25 2016 done: Mon Nov 7 18:00:25 2016
Total Scan time: 5.060 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]