Result of FASTA (omim) for
pFN21AE9560
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9560, 385 aa
1>>>pF1KE9560 385 - 385 aa - 385 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6149+/-0.000365; mu= 15.9982+/- 0.023
mean_var=114.3661+/-25.753, 0's: 0 Z-trim(116.2): 652 B-trim: 1384 in 1/50
Lambda= 0.119929
statistics sampled from 26402 (27172) to 26402 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.319), width: 16
Scan time: 8.410
The best scores are: opt bits E(85289)
NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 2562 454.4 2.1e-127
XP_005260196 (OMIM: 602779) PREDICTED: proteinase- ( 273) 1798 322.0 1e-87
NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 693 131.0 4.3e-30
NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 693 131.0 4.5e-30
XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 662 125.6 1.9e-28
NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 662 125.7 1.9e-28
NP_001983 (OMIM: 187930) proteinase-activated rece ( 425) 615 117.6 5.7e-26
XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 594 114.0 8.4e-25
XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 594 114.0 8.4e-25
XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 587 112.6 1.5e-24
XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 587 112.6 1.5e-24
XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 587 112.6 1.5e-24
NP_835230 (OMIM: 300525) P2Y purinoceptor 8 [Homo ( 359) 587 112.6 1.5e-24
XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 587 112.6 1.5e-24
XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 587 112.6 1.5e-24
XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 587 112.6 1.5e-24
NP_001298242 (OMIM: 187930) proteinase-activated r ( 304) 550 106.2 1.1e-22
XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 479 94.0 6.2e-19
NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 479 94.0 6.2e-19
NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 479 94.0 6.2e-19
NP_001727 (OMIM: 113995) C5a anaphylatoxin chemota ( 350) 477 93.6 7.7e-19
NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 475 93.2 9.6e-19
NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 475 93.2 9.6e-19
NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 91.5 3.2e-18
NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 91.5 3.2e-18
NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 91.5 3.2e-18
NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 91.5 3.2e-18
NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 91.5 3.2e-18
NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 465 91.5 3.2e-18
NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 91.5 3.2e-18
NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 465 91.5 3.2e-18
NP_005289 (OMIM: 602174) probable G-protein couple ( 361) 454 89.6 1.2e-17
NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 437 86.7 9.6e-17
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 436 86.5 1e-16
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 434 86.2 1.3e-16
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 432 85.8 1.7e-16
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 432 85.8 1.7e-16
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 432 85.8 1.7e-16
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 432 85.8 1.7e-16
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 432 85.8 1.8e-16
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 432 85.8 1.8e-16
NP_789767 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 431 85.6 1.8e-16
NP_001264133 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 431 85.6 1.8e-16
XP_011543381 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 431 85.6 1.8e-16
NP_001264136 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 431 85.6 1.8e-16
XP_005274079 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 431 85.6 1.8e-16
XP_011543379 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 431 85.6 1.8e-16
NP_789768 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 431 85.6 1.8e-16
NP_789766 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 431 85.6 1.8e-16
NP_001264134 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 431 85.6 1.8e-16
>>NP_003941 (OMIM: 602779) proteinase-activated receptor (385 aa)
initn: 2562 init1: 2562 opt: 2562 Z-score: 2408.4 bits: 454.4 E(85289): 2.1e-127
Smith-Waterman score: 2562; 99.7% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KE9 MWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_003 LELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 PLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 WQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSP
310 320 330 340 350 360
370 380
pF1KE9 GDTVASKASAEGGSRGMGTHSSLLQ
:::::::::::::::::::::::::
NP_003 GDTVASKASAEGGSRGMGTHSSLLQ
370 380
>>XP_005260196 (OMIM: 602779) PREDICTED: proteinase-acti (273 aa)
initn: 1798 init1: 1798 opt: 1798 Z-score: 1695.8 bits: 322.0 E(85289): 1e-87
Smith-Waterman score: 1798; 99.6% identity (100.0% similar) in 273 aa overlap (113-385:1-273)
90 100 110 120 130 140
pF1KE9 LYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLATADLLLALALPPRIAYHLRGQRW
:::::::.::::::::::::::::::::::
XP_005 MLLMNLAAADLLLALALPPRIAYHLRGQRW
10 20 30
150 160 170 180 190 200
pF1KE9 PFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWL
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE9 MAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLL
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE9 CYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAY
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE9 VPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSS
220 230 240 250 260 270
pF1KE9 LLQ
:::
XP_005 LLQ
>>NP_001243495 (OMIM: 601919) proteinase-activated recep (352 aa)
initn: 676 init1: 467 opt: 693 Z-score: 661.2 bits: 131.0 E(85289): 4.3e-30
Smith-Waterman score: 693; 36.9% identity (69.6% similar) in 293 aa overlap (54-344:48-340)
30 40 50 60 70 80
pF1KE9 SVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDT-LELPDSSRALLLGWVPTRLVPA
: ..: . :.. ... . : . . :.:.::
NP_001 FRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPA
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE9 LYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLATADLLLALALPPRIAYHLRGQRW
.: ::.:::.:::...::.: .. . .:.. ::: ::.:. ..:: .::::: :. :
NP_001 IYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNW
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE9 PFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWL
:::. :: .:. .::.:: :.:::: .:..::::.:::. :.: . :: : .:
NP_001 VFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWA
140 150 160 170 180 190
210 220 230 240 250 260
pF1KE9 MAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQ-PAFTCLALLGCFLPLLAML
. ::. . .: . :.. : . :::. ..: .: : ::..: ..:.. ..
NP_001 TVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLII
200 210 220 230 240 250
270 280 290 300 310 320
pF1KE9 LCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGA
::.: ..:: : .:. .. . ..:. . :.:::..:..:... . .::
NP_001 YCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFI
260 270 280 290 300 310
330 340 350 360 370 380
pF1KE9 YVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHS
:. .: :..::::.:::.:. .:
NP_001 YLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
320 330 340 350
>>NP_004092 (OMIM: 601919) proteinase-activated receptor (374 aa)
initn: 676 init1: 467 opt: 693 Z-score: 660.9 bits: 131.0 E(85289): 4.5e-30
Smith-Waterman score: 693; 36.9% identity (69.6% similar) in 293 aa overlap (54-344:70-362)
30 40 50 60 70 80
pF1KE9 SVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDT-LELPDSSRALLLGWVPTRLVPA
: ..: . :.. ... . : . . :.:.::
NP_004 FRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPA
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE9 LYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLATADLLLALALPPRIAYHLRGQRW
.: ::.:::.:::...::.: .. . .:.. ::: ::.:. ..:: .::::: :. :
NP_004 IYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNW
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE9 PFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWL
:::. :: .:. .::.:: :.:::: .:..::::.:::. :.: . :: : .:
NP_004 VFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWA
160 170 180 190 200 210
210 220 230 240 250 260
pF1KE9 MAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQ-PAFTCLALLGCFLPLLAML
. ::. . .: . :.. : . :::. ..: .: : ::..: ..:.. ..
NP_004 TVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLII
220 230 240 250 260 270
270 280 290 300 310 320
pF1KE9 LCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGA
::.: ..:: : .:. .. . ..:. . :.:::..:..:... . .::
NP_004 YCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFI
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE9 YVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHS
:. .: :..::::.:::.:. .:
NP_004 YLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
340 350 360 370
>>XP_016864712 (OMIM: 600933) PREDICTED: proteinase-acti (383 aa)
initn: 462 init1: 252 opt: 662 Z-score: 631.8 bits: 125.6 E(85289): 1.9e-28
Smith-Waterman score: 662; 36.5% identity (68.1% similar) in 301 aa overlap (67-359:51-349)
40 50 60 70 80 90
pF1KE9 DSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANG
: ..: : . : ..: .: .:.:::::.::
XP_016 GRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNG
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE9 LALWV-LATQAPRLPSTMLLMNLATADLLLALALPPRIAYHLRGQRWPFGEAACRLATAA
.:::: : . :... . ::: :::: .. .: .::::..:. : .::: : . .
XP_016 MALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGF
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE9 LYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQR
.::.:: :.:... .:..:: ..:.:. ... . .:.:. .: ::. ...:: . .
XP_016 FYGNMYCSILFMTCLSVQRYWVIVNPM-GHSRKKANIAIGISLAIWLLILLVTIPLYVVK
150 160 170 180 190
220 230 240 250 260 270
pF1KE9 QTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFL-PLLAMLLCYGATLHTLAAS
::. . . . :::.:: . .. : ::. : :: : . : .. : .:
XP_016 QTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAI-GVFLFPAFLTASAYVLMIRMLRSS
200 210 220 230 240 250
280 290 300 310 320
pF1KE9 G------RRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLAL
. .. .:..: ..::: . :.::::::..:: . .. ...:. :. .: :
XP_016 AMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCL
260 270 280 290 300 310
330 340 350 360 370 380
pF1KE9 STLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ
::::::.:::.::.:: .:::... .:. ::
XP_016 STLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTT
320 330 340 350 360 370
XP_016 VKTSY
380
>>NP_005233 (OMIM: 600933) proteinase-activated receptor (397 aa)
initn: 462 init1: 252 opt: 662 Z-score: 631.6 bits: 125.7 E(85289): 1.9e-28
Smith-Waterman score: 662; 36.5% identity (68.1% similar) in 301 aa overlap (67-359:65-363)
40 50 60 70 80 90
pF1KE9 DSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANG
: ..: : . : ..: .: .:.:::::.::
NP_005 GRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNG
40 50 60 70 80 90
100 110 120 130 140 150
pF1KE9 LALWV-LATQAPRLPSTMLLMNLATADLLLALALPPRIAYHLRGQRWPFGEAACRLATAA
.:::: : . :... . ::: :::: .. .: .::::..:. : .::: : . .
NP_005 MALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGF
100 110 120 130 140 150
160 170 180 190 200 210
pF1KE9 LYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQR
.::.:: :.:... .:..:: ..:.:. ... . .:.:. .: ::. ...:: . .
NP_005 FYGNMYCSILFMTCLSVQRYWVIVNPM-GHSRKKANIAIGISLAIWLLILLVTIPLYVVK
160 170 180 190 200 210
220 230 240 250 260 270
pF1KE9 QTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFL-PLLAMLLCYGATLHTLAAS
::. . . . :::.:: . .. : ::. : :: : . : .. : .:
NP_005 QTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAI-GVFLFPAFLTASAYVLMIRMLRSS
220 230 240 250 260 270
280 290 300 310 320
pF1KE9 G------RRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLAL
. .. .:..: ..::: . :.::::::..:: . .. ...:. :. .: :
NP_005 AMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCL
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE9 STLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ
::::::.:::.::.:: .:::... .:. ::
NP_005 STLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTT
340 350 360 370 380 390
NP_005 VKTSY
>>NP_001983 (OMIM: 187930) proteinase-activated receptor (425 aa)
initn: 618 init1: 373 opt: 615 Z-score: 587.3 bits: 117.6 E(85289): 5.7e-26
Smith-Waterman score: 615; 33.6% identity (64.6% similar) in 345 aa overlap (53-384:72-415)
30 40 50 60 70
pF1KE9 PSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDTLE--LP-----DSSRALLLGWV
: : :. :. :: :.: : .:.
NP_001 SFLLRNPNDKYEPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWL
50 60 70 80 90 100
80 90 100 110 120 130
pF1KE9 PTRLVPALYGLVLVVGLPANGLALWVLATQAP-RLPSTMLLMNLATADLLLALALPPRIA
: .::..: :.::.:: : .:. :. . . :... ...:::::.:.. .:: .:.
NP_001 -TLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKIS
110 120 130 140 150 160
140 150 160 170 180 190
pF1KE9 YHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLAL
:.. :. : :: ::..:::.: .::.:.::....:.::.::.:.:... . : :
NP_001 YYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRAS
170 180 190 200 210 220
200 210 220 230 240 250
pF1KE9 GLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCF
:.: : .: : ..:: :..::... . . :::.: ... :. .. . :
NP_001 FTCLAIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFF
230 240 250 260 270 280
260 270 280 290 300 310
pF1KE9 LPLLAMLLCYGATLHTLAASG----RRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDP
.::. .:: . .. :..:. . ..:: :.:.:. . : :.:.::. :::
NP_001 VPLIISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFL
290 300 310 320 330 340
320 330 340 350 360
pF1KE9 S-PSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKAS
: :. : ::. . .:... :.::.::::.:.: . : . : . .: . ..:
NP_001 SHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSS
350 360 370 380 390 400
370 380
pF1KE9 AEGGSRGMGTHSSLLQ
.. . : : :: :
NP_001 GQLMASKMDTCSSNLNNSIYKKLLT
410 420
>>XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinocepto (548 aa)
initn: 523 init1: 291 opt: 594 Z-score: 566.3 bits: 114.0 E(85289): 8.4e-25
Smith-Waterman score: 594; 31.6% identity (63.8% similar) in 367 aa overlap (31-381:160-524)
10 20 30 40 50 60
pF1KE9 MWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDT
: ::.. .. .: . . ..: .
XP_006 QKFLDSHLCRPDTAKNNRCADFLKFPSCPLSPGGAQTASLCLLCQGSWHQLESPGEDPSR
130 140 150 160 170 180
70 80 90 100 110
pF1KE9 LELPDSS----RALLLGWVPTRLV--PALYGLVLVVGLPANGLALWVLATQ-APRLPSTM
...:.:. .: . :. : :..:.:: .:..:.: ..:::: . .:: ::..
XP_006 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVI
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE9 LLMNLATADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLD
...::...::.:: .:: .: :: ..: :: : ..:.:.:..::.:.: .. .:..
XP_006 FMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVE
250 260 270 280 290 300
180 190 200 210 220 230
pF1KE9 RYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALP
:.:....:: .. : :: :.. : ..::. . ::. :. . . : :.:
XP_006 RFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLK
310 320 330 340 350 360
240 250 260 270 280
pF1KE9 --LDAQASHWQPAFTCLALLGCFLPLLAMLLCYGAT----LHTLAASGR-RYGHALRLTA
. ... : . . .: ..:.. . :: :: :.: : :: . .:. :.:
XP_006 WTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAA
370 380 390 400 410 420
290 300 310 320 330 340
pF1KE9 VVLASAVAFFVPSNLLLLLHYSDPSPSAWG-NLYGAYVPSLALSTLNSCVDPFIYYYVSA
::: . :. :.:.:..:: : : .: . : .: .: :: ::.:.:::.::..:
XP_006 VVLLAFVTCFAPNNFVLLAHIV--SRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASR
430 440 450 460 470 480
350 360 370 380
pF1KE9 EFRDKVRAGL-FQRSPGDTVASKASAEGGSRGMGTHSSLLQ
::. ..: : .: : ::. .. . ..: ...:
XP_006 EFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQESV
490 500 510 520 530 540
XP_006 F
>>XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinocepto (548 aa)
initn: 523 init1: 291 opt: 594 Z-score: 566.3 bits: 114.0 E(85289): 8.4e-25
Smith-Waterman score: 594; 31.6% identity (63.8% similar) in 367 aa overlap (31-381:160-524)
10 20 30 40 50 60
pF1KE9 MWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDT
: ::.. .. .: . . ..: .
XP_006 QKFLDSHLCRPDTAKNNRCADFLKFPSCPLSPGGAQTASLCLLCQGSWHQLESPGEDPSR
130 140 150 160 170 180
70 80 90 100 110
pF1KE9 LELPDSS----RALLLGWVPTRLV--PALYGLVLVVGLPANGLALWVLATQ-APRLPSTM
...:.:. .: . :. : :..:.:: .:..:.: ..:::: . .:: ::..
XP_006 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVI
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE9 LLMNLATADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLD
...::...::.:: .:: .: :: ..: :: : ..:.:.:..::.:.: .. .:..
XP_006 FMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVE
250 260 270 280 290 300
180 190 200 210 220 230
pF1KE9 RYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALP
:.:....:: .. : :: :.. : ..::. . ::. :. . . : :.:
XP_006 RFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLK
310 320 330 340 350 360
240 250 260 270 280
pF1KE9 --LDAQASHWQPAFTCLALLGCFLPLLAMLLCYGAT----LHTLAASGR-RYGHALRLTA
. ... : . . .: ..:.. . :: :: :.: : :: . .:. :.:
XP_006 WTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAA
370 380 390 400 410 420
290 300 310 320 330 340
pF1KE9 VVLASAVAFFVPSNLLLLLHYSDPSPSAWG-NLYGAYVPSLALSTLNSCVDPFIYYYVSA
::: . :. :.:.:..:: : : .: . : .: .: :: ::.:.:::.::..:
XP_006 VVLLAFVTCFAPNNFVLLAHIV--SRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASR
430 440 450 460 470 480
350 360 370 380
pF1KE9 EFRDKVRAGL-FQRSPGDTVASKASAEGGSRGMGTHSSLLQ
::. ..: : .: : ::. .. . ..: ...:
XP_006 EFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQESV
490 500 510 520 530 540
XP_006 F
>>XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 523 init1: 291 opt: 587 Z-score: 562.0 bits: 112.6 E(85289): 1.5e-24
Smith-Waterman score: 587; 34.0% identity (66.3% similar) in 312 aa overlap (80-381:26-335)
50 60 70 80 90 100
pF1KE9 PGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQ-APR
.:..:.:: .:..:.: ..:::: . .::
XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPR
10 20 30 40 50
110 120 130 140 150 160
pF1KE9 LPSTMLLMNLATADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLA
::.....::...::.:: .:: .: :: ..: :: : ..:.:.:..::.:.: ..
XP_011 SPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMT
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE9 AVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLC
.:..:.:....:: .. : :: :.. : ..::. . ::. :. . . :
XP_011 CISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITC
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE9 HDALP--LDAQASHWQPAFTCLALLGCFLPLLAMLLCYGAT----LHTLAASGR-RYGHA
:.: . ... : . . .: ..:.. . :: :: :.: : :: . .:
XP_011 FDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRA
180 190 200 210 220 230
290 300 310 320 330 340
pF1KE9 LRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWG-NLYGAYVPSLALSTLNSCVDPFIY
. :.:::: . :. :.:.:..:: : : .: . : .: .: :: ::.:.:::.:
XP_011 VGLAAVVLLAFVTCFAPNNFVLLAHIV--SRLFYGKSYYHVYKLTLCLSCLNNCLDPFVY
240 250 260 270 280 290
350 360 370 380
pF1KE9 YYVSAEFRDKVRAGL-FQRSPGDTVASKASAEGGSRGMGTHSSLLQ
:..: ::. ..: : .: : ::. .. . ..: ...:
XP_011 YFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQ
300 310 320 330 340 350
XP_011 RQESVF
385 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:02:47 2016 done: Sun Nov 6 07:02:48 2016
Total Scan time: 8.410 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]