Result of FASTA (omim) for
pFN21AE9548
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9548, 398 aa
1>>>pF1KE9548 398 - 398 aa - 398 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8267+/-0.000426; mu= 19.6477+/- 0.027
mean_var=104.9699+/-26.153, 0's: 0 Z-trim(111.2): 745 B-trim: 974 in 1/50
Lambda= 0.125182
statistics sampled from 18898 (19751) to 18898 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.585), E-opt: 0.2 (0.232), width: 16
Scan time: 7.830
The best scores are: opt bits E(85289)
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 2679 495.3 1.1e-139
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 1330 251.7 2.6e-66
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 1304 247.0 6.3e-65
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 1192 226.6 6.5e-59
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 581 116.4 1.3e-25
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 508 103.2 1.1e-21
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 508 103.2 1.1e-21
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 508 103.2 1.1e-21
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 503 102.2 2.1e-21
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 489 99.7 1.2e-20
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 489 99.7 1.2e-20
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 489 99.7 1.2e-20
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 467 95.7 1.9e-19
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 460 94.4 4.4e-19
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 460 94.5 4.6e-19
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 460 94.5 4.6e-19
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 460 94.5 4.7e-19
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 447 92.2 2.5e-18
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 447 92.2 2.5e-18
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 447 92.2 2.5e-18
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 447 92.2 2.5e-18
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 447 92.2 2.5e-18
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 447 92.2 2.5e-18
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 447 92.2 2.5e-18
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 445 91.8 3.1e-18
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 438 90.5 7.1e-18
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 433 89.7 1.4e-17
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 432 89.5 1.6e-17
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 429 88.9 2.2e-17
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 429 88.9 2.2e-17
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 429 88.9 2.3e-17
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 89.0 2.4e-17
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 89.0 2.4e-17
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 89.0 2.4e-17
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 89.0 2.4e-17
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 429 89.0 2.4e-17
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 426 88.4 3.3e-17
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 426 88.4 3.4e-17
NP_003605 (OMIM: 603692) galanin receptor type 3 [ ( 368) 423 87.8 4.6e-17
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 423 87.8 4.9e-17
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 423 88.0 5.5e-17
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 423 88.0 5.5e-17
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 421 87.4 5.8e-17
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 420 87.3 7e-17
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 420 87.3 7e-17
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 420 87.3 7.1e-17
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 420 87.3 7.1e-17
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 420 87.3 7.3e-17
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 420 87.3 7.3e-17
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 420 87.3 7.3e-17
>>NP_001048 (OMIM: 162321) substance-K receptor [Homo sa (398 aa)
initn: 2679 init1: 2679 opt: 2679 Z-score: 2628.8 bits: 495.3 E(85289): 1.1e-139
Smith-Waterman score: 2679; 99.5% identity (99.5% similar) in 398 aa overlap (1-398:1-398)
10 20 30 40 50 60
pF1KE9 MGTCDIVTEANISSGPESNTTGTTAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
NP_001 MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 HLQAKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
310 320 330 340 350 360
370 380 390
pF1KE9 GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
::::::::::::::::::::::::::::::::::::::
NP_001 GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
370 380 390
>>NP_001050 (OMIM: 162332,614840) neuromedin-K receptor (465 aa)
initn: 1307 init1: 728 opt: 1330 Z-score: 1311.4 bits: 251.7 E(85289): 2.6e-66
Smith-Waterman score: 1330; 53.4% identity (75.6% similar) in 373 aa overlap (14-380:68-435)
10 20 30 40
pF1KE9 MGTCDIVTEANISSGPESNTTGTTAFSMPSWQLALWATAYLAL
: : .: :. : .:::..:::. :: ..
NP_001 ETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTN--QFVQPSWRIALWSLAYGVV
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE9 VLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGR
: ::: :: :::::::::.:::::::::.::::..: :::::. ::.:: :. ::::
NP_001 VAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGA
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE9 AFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALA
.: :::.:::::.:.:::::::::.::::::. :..::::: .:: ::..::..:. ::
NP_001 NYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLA
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE9 SPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLT
:::.:: . . : : : : ::: : : . ::..:: :.: .:: .: ..:...:.:
NP_001 FPQCLYSKTKVMPGRTLCFVQWPE--GPKQHFTYHIIVIILVYCFPLLIMGITYTIVGIT
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE9 LWRRAVPGHQAHGANLRHLQAKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHK
:: .:: . ..:.::.: :: :..::.::::::::::.:::: .. ... :
NP_001 LWGGEIPGDTCDKYH-EQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWK
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE9 FIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTS
.::::::: :::::::::::::::::::.:::.::. ::: ::.. .. :.::: :
NP_001 YIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELKTTRF
340 350 360 370 380 390
350 360 370 380 390
pF1KE9 LSTR------VNRCHTKETLFMAGDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVE
.: :.: .. ..: .:. .... . . :.: :
NP_001 HPNRQSSMYTVTRMESMTVVFDPNDADTTRSSRKKRATPRDPSFNGCSRRNSKSASATSS
400 410 420 430 440 450
pF1KE9 I
NP_001 FISSPYTSVDEYS
460
>>NP_001049 (OMIM: 162323) substance-P receptor isoform (407 aa)
initn: 1296 init1: 840 opt: 1304 Z-score: 1286.7 bits: 247.0 E(85289): 6.3e-65
Smith-Waterman score: 1304; 50.9% identity (77.9% similar) in 371 aa overlap (9-379:8-372)
10 20 30 40 50 60
pF1KE9 MGTCDIVTEANISSGPESNTTGTTAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
....: . .::. . : .:.::..:::.:: ..:...:.::..:.:::::
NP_001 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILA
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
:.:::::::::.::::.:. :::::.. ::.:: :: ::.: .: :.:.:::.:.:.:
NP_001 HKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
::::::.: ::::::.::.:::::: .::.:: ::..:: :: :: .:::. . .
NP_001 IYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
:.. ::: . .::. : .::::::: :. ::.:.:.::: .:: .. . .
NP_001 CMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYH-E
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 HLQAKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
...::.: :: :..:: ::::::::.:..:.: .. :.: .:::::::::..:::::::
NP_001 QVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSST
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
::::::::::: ::: ::. ::::::... . ::. : :.:. . ....
NP_001 MYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRL----
300 310 320 330 340 350
370 380 390
pF1KE9 GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
.:. : ..... .:.::
NP_001 -ETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS
360 370 380 390 400
>>NP_056542 (OMIM: 162323) substance-P receptor isoform (311 aa)
initn: 1186 init1: 840 opt: 1192 Z-score: 1178.6 bits: 226.6 E(85289): 6.5e-59
Smith-Waterman score: 1192; 55.4% identity (81.0% similar) in 305 aa overlap (9-313:8-311)
10 20 30 40 50 60
pF1KE9 MGTCDIVTEANISSGPESNTTGTTAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
....: . .::. . : .:.::..:::.:: ..:...:.::..:.:::::
NP_056 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILA
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
:.:::::::::.::::.:. :::::.. ::.:: :: ::.: .: :.:.:::.:.:.:
NP_056 HKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
::::::.: ::::::.::.:::::: .::.:: ::..:: :: :: .:::. . .
NP_056 IYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
:.. ::: . .::. : .::::::: :. ::.:.:.::: .:: .. . .
NP_056 CMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYH-E
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 HLQAKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
...::.: :: :..:: ::::::::.:..:.: .. :.: .:::::::::..:::::::
NP_056 QVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSST
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
::::::::::: :
NP_056 MYNPIIYCCLNDR
300 310
>>NP_057624 (OMIM: 605569) probable G-protein coupled re (423 aa)
initn: 370 init1: 370 opt: 581 Z-score: 580.8 bits: 116.4 E(85289): 1.3e-25
Smith-Waterman score: 581; 31.3% identity (61.2% similar) in 345 aa overlap (34-372:72-410)
10 20 30 40 50 60
pF1KE9 CDIVTEANISSGPESNTTGTTAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRR
:: .:: ... .. ::..: .:. ..:
NP_057 FSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQR
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE9 MRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYS
:...:. ::::::.::. .. .:. :..: .. : ::...:. . . .. :: .
NP_057 MHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALT
110 120 130 140 150 160
130 140 150 160 170
pF1KE9 MTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQ--C---FYSTVTMDQGA
.::::.::...:.::..::.: . :: :: .: .. :. : : . :
NP_057 LTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVR
170 180 190 200 210 220
180 190 200 210 220 230
pF1KE9 TKCVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGAN
. :. .:: . : :... :.:.::: .. :::. .. :: . : .
NP_057 SLCLPDFPEPADLFWKYL-DLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQY
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE9 LRHLQAKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMS
. . ::: .: ..:::. ::.::.: . : .: : . . . .:.:. :.:::
NP_057 FALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLLLSSK----VIRTNNALYFAFHWFAMS
290 300 310 320 330
300 310 320 330 340 350
pF1KE9 STMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLF
:: :::.::: ::. :: .. . : .::. .:. :. . .. . .
NP_057 STCYNPFIYCWLNENFRIELKALLSMCQRPPKPQEDR-PPSPVPSFRVAWTEKNDGQRAP
340 350 360 370 380 390
360 370 380 390
pF1KE9 MAGDTAP-SEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
.:.. : :. ::.
NP_057 LANNLLPTSQLQSGKTDLSSVEPIVTMS
400 410 420
>>NP_000901 (OMIM: 162642) neuropeptide Y receptor type (381 aa)
initn: 518 init1: 272 opt: 508 Z-score: 510.1 bits: 103.2 E(85289): 1.1e-21
Smith-Waterman score: 508; 30.9% identity (61.9% similar) in 291 aa overlap (39-324:56-342)
10 20 30 40 50 60
pF1KE9 EANISSGPESNTTGTTAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVT
:: ...:..: ::..:: ... . :::::
NP_000 TTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVT
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE9 NYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIA
:.::.:::.::: . .. :...:. . : .: ..:.. :. :: ..:.::
NP_000 NFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIA
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE9 ADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCF---YSTVTM--DQGATKCVV
::. ::. .. ..: . .:. : .. :::: . :: . . : . :.
NP_000 LDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTE
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE9 AWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQ
:: . . .: : . ..: :::... .:. : : .. :: .:: .. :
NP_000 KWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPG----AANDHYHQ
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE9 AKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYN
..: .: .: ::..::. ::: : . . ... .. : . .. .. .:: ::. :
NP_000 RRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFAN
270 280 290 300 310 320
310 320 330 340 350 360
pF1KE9 PIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMAGDT
:..: .: .:..: ::::
NP_000 PLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
330 340 350 360 370 380
>>XP_005263090 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 518 init1: 272 opt: 508 Z-score: 510.1 bits: 103.2 E(85289): 1.1e-21
Smith-Waterman score: 508; 30.9% identity (61.9% similar) in 291 aa overlap (39-324:56-342)
10 20 30 40 50 60
pF1KE9 EANISSGPESNTTGTTAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVT
:: ...:..: ::..:: ... . :::::
XP_005 TTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVT
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE9 NYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIA
:.::.:::.::: . .. :...:. . : .: ..:.. :. :: ..:.::
XP_005 NFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIA
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE9 ADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCF---YSTVTM--DQGATKCVV
::. ::. .. ..: . .:. : .. :::: . :: . . : . :.
XP_005 LDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTE
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE9 AWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQ
:: . . .: : . ..: :::... .:. : : .. :: .:: .. :
XP_005 KWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPG----AANDHYHQ
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE9 AKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYN
..: .: .: ::..::. ::: : . . ... .. : . .. .. .:: ::. :
XP_005 RRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFAN
270 280 290 300 310 320
310 320 330 340 350 360
pF1KE9 PIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMAGDT
:..: .: .:..: ::::
XP_005 PLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
330 340 350 360 370 380
>>XP_005263091 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 518 init1: 272 opt: 508 Z-score: 510.1 bits: 103.2 E(85289): 1.1e-21
Smith-Waterman score: 508; 30.9% identity (61.9% similar) in 291 aa overlap (39-324:56-342)
10 20 30 40 50 60
pF1KE9 EANISSGPESNTTGTTAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVT
:: ...:..: ::..:: ... . :::::
XP_005 TTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVT
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE9 NYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIA
:.::.:::.::: . .. :...:. . : .: ..:.. :. :: ..:.::
XP_005 NFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIA
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE9 ADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCF---YSTVTM--DQGATKCVV
::. ::. .. ..: . .:. : .. :::: . :: . . : . :.
XP_005 LDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTE
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE9 AWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQ
:: . . .: : . ..: :::... .:. : : .. :: .:: .. :
XP_005 KWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPG----AANDHYHQ
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE9 AKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYN
..: .: .: ::..::. ::: : . . ... .. : . .. .. .:: ::. :
XP_005 RRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFAN
270 280 290 300 310 320
310 320 330 340 350 360
pF1KE9 PIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMAGDT
:..: .: .:..: ::::
XP_005 PLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
330 340 350 360 370 380
>>NP_004239 (OMIM: 600895) prolactin-releasing peptide r (370 aa)
initn: 492 init1: 357 opt: 503 Z-score: 505.3 bits: 102.2 E(85289): 2.1e-21
Smith-Waterman score: 503; 30.0% identity (64.4% similar) in 323 aa overlap (9-319:31-347)
10 20 30
pF1KE9 MGTCDIVTEANISSGPESNTTGTTAFSMPSWQLA----
::. ..: ... . .. . : ::.
NP_004 MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE9 -LWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVY
: . : ..:.:...:: ... .: ::...:::..: ::::.:. : . . ....:
NP_004 GLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE9 ASH-NIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVI
: . : :: ..:.. .. ....::....:.::.:::...:::.. :.: . ..
NP_004 AFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE9 AGIWLVALALASPQCFYST-VTMDQGATK-CVVAWPEDSGGKTLLLYHLVVIALIYFLPL
.:: .. .:: : .. : . .. : : . . : . :.... :.:::
NP_004 LAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVT--YLLPL
190 200 210 220 230
220 230 240 250 260
pF1KE9 AVMFVAYSVIGLTLWRRAVPGHQAHG-ANLRHLQAKKKFVKTMVLVVLTFAICWLPYHLY
:....: ... : :.::: ... :. . . .. : .:.::..::.:::: :..
NP_004 LVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFC-LLVVVVVVFAVCWLPLHVF
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE9 FILGSFQE---DIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCP
.: ... : : ..: : ::::::. :::.:: :. :: .:
NP_004 NLLRDLDPHAIDPYAFGLVQ---LLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWP
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE9 WVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMAGDTAPSEATSGEAGRPQDGSGLWFGY
NP_004 RKIAPHGQNMTVSVVI
360 370
>>NP_000900 (OMIM: 162641) neuropeptide Y receptor type (384 aa)
initn: 457 init1: 282 opt: 489 Z-score: 491.5 bits: 99.7 E(85289): 1.2e-20
Smith-Waterman score: 503; 30.5% identity (60.1% similar) in 341 aa overlap (28-355:35-366)
10 20 30 40 50
pF1KE9 MGTCDIVTEANISSGPESNTTGTTAFSMPSWQLALWATAYLALVLVAVTGNAIVIWI
.: .. : :: :.....:.:: .: :
NP_000 LFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIII
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 ILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAM
:: ...::.::: .::::...:: .: . :.:::. . : ::.:.: .. . ...
NP_000 ILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 FVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYST------
:::.:.. ::..:.. :..: : . . . :: ::..:.: . : .:..
NP_000 TVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPF
130 140 150 160 170 180
180 190 200 210 220
pF1KE9 --VTMDQGATK--CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRR
::.: : : .: :: : : ....: :: :: .:. : : . : ::
NP_000 QNVTLDAYKDKYVCFDQFPSDSHR---LSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 AVPGHQAHGANLRHLQAKKKFVKTMVL-VVLTFAICWLPYHLYFILGSFQEDIY--CHKF
. . . : ..:. .. :.: .:..::.:::: .. . .....: :..
NP_000 NNMMDKMRDNKYRSSETKR--INIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHN
250 260 270 280 290
290 300 310 320 330 340
pF1KE9 IQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSL
. ..: :: :: :::.: ::. :. ... : : . . ..: : ...
NP_000 L--LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRS--RDDDYETIAMSTM
300 310 320 330 340 350
350 360 370 380 390
pF1KE9 STRVNRCHTKETLFMAGDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
: :.. :.
NP_000 HTDVSKTSLKQASPVAFKKINNNDDNEKI
360 370 380
398 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:26:19 2016 done: Sun Nov 6 15:26:20 2016
Total Scan time: 7.830 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]