Result of FASTA (omim) for
pFN21AE9531
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9531, 295 aa
1>>>pF1KE9531 295 - 295 aa - 295 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7113+/-0.000422; mu= 18.4253+/- 0.026
mean_var=81.1102+/-20.575, 0's: 0 Z-trim(110.7): 304 B-trim: 2303 in 2/52
Lambda= 0.142409
statistics sampled from 18598 (19064) to 18598 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.578), E-opt: 0.2 (0.224), width: 16
Scan time: 7.180
The best scores are: opt bits E(85289)
NP_002912 (OMIM: 600342,613769) RPE-retinal G prot ( 295) 1973 415.5 6.3e-116
NP_001012738 (OMIM: 600342,613769) RPE-retinal G p ( 291) 1928 406.2 3.8e-113
NP_001012740 (OMIM: 600342,613769) RPE-retinal G p ( 253) 1397 297.1 2.4e-80
NP_006574 (OMIM: 605224) visual pigment-like recep ( 337) 358 83.7 5.3e-16
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 325 77.1 7.4e-14
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 325 77.2 7.9e-14
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] ( 402) 301 72.1 2e-12
NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] ( 354) 295 70.8 4.3e-12
XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 iso ( 408) 295 70.9 4.7e-12
XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 iso ( 298) 288 69.3 1e-11
NP_000530 (OMIM: 136880,180380,610445,613731) rhod ( 348) 269 65.5 1.7e-10
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 258 63.3 9.2e-10
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 258 63.4 1e-09
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 258 63.4 1.1e-09
NP_005949 (OMIM: 600665) melatonin receptor type 1 ( 350) 218 55.0 2.5e-07
XP_011515565 (OMIM: 188545) PREDICTED: thyrotropin ( 398) 209 53.2 9.7e-07
NP_003292 (OMIM: 188545) thyrotropin-releasing hor ( 398) 209 53.2 9.7e-07
NP_004215 (OMIM: 300207) melatonin-related recepto ( 617) 202 52.0 3.5e-06
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 197 50.7 5e-06
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 197 50.7 5e-06
NP_001137391 (OMIM: 601531) leukotriene B4 recepto ( 352) 195 50.3 6.6e-06
NP_858043 (OMIM: 601531) leukotriene B4 receptor 1 ( 352) 195 50.3 6.6e-06
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 195 50.4 7.5e-06
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 195 50.4 7.7e-06
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 195 50.4 8.1e-06
NP_005279 (OMIM: 600752) G-protein coupled recepto ( 334) 189 49.0 1.5e-05
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 190 49.4 1.6e-05
XP_016865901 (OMIM: 609042) PREDICTED: opsin-5 iso ( 285) 185 48.1 2.4e-05
XP_016865902 (OMIM: 609042) PREDICTED: opsin-5 iso ( 285) 185 48.1 2.4e-05
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 186 48.4 2.4e-05
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 186 48.4 2.4e-05
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 186 48.4 2.4e-05
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 186 48.4 2.4e-05
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 186 48.5 2.5e-05
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 186 48.5 2.5e-05
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 186 48.5 2.5e-05
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 186 48.5 2.6e-05
NP_004113 (OMIM: 601898) growth hormone secretagog ( 289) 183 47.7 3.2e-05
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 183 47.8 3.7e-05
XP_016865899 (OMIM: 609042) PREDICTED: opsin-5 iso ( 299) 182 47.5 3.7e-05
NP_001699 (OMIM: 190900,613522) short-wave-sensiti ( 348) 180 47.2 5.5e-05
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 180 47.3 6.8e-05
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 178 46.8 7.8e-05
NP_065103 (OMIM: 606383) G-protein coupled recepto ( 396) 178 46.8 8e-05
XP_011536797 (OMIM: 606383) PREDICTED: G-protein c ( 396) 178 46.8 8e-05
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 178 46.8 8.2e-05
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 178 46.8 8.2e-05
NP_871001 (OMIM: 609043) relaxin-3 receptor 2 [Hom ( 374) 177 46.6 8.9e-05
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 176 46.4 0.00011
NP_005272 (OMIM: 600241) G-protein coupled recepto ( 330) 170 45.1 0.00022
>>NP_002912 (OMIM: 600342,613769) RPE-retinal G protein- (295 aa)
initn: 1973 init1: 1973 opt: 1973 Z-score: 2202.2 bits: 415.5 E(85289): 6.3e-116
Smith-Waterman score: 1973; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KE9 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI
190 200 210 220 230 240
250 260 270 280 290
pF1KE9 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
250 260 270 280 290
>>NP_001012738 (OMIM: 600342,613769) RPE-retinal G prote (291 aa)
initn: 1477 init1: 1477 opt: 1928 Z-score: 2152.3 bits: 406.2 E(85289): 3.8e-113
Smith-Waterman score: 1928; 98.6% identity (98.6% similar) in 295 aa overlap (1-295:1-291)
10 20 30 40 50 60
pF1KE9 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
:::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 ADSGISLNALVAATSSLL----RRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
70 80 90 100 110
130 140 150 160 170 180
pF1KE9 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
240 250 260 270 280 290
>>NP_001012740 (OMIM: 600342,613769) RPE-retinal G prote (253 aa)
initn: 946 init1: 946 opt: 1397 Z-score: 1563.4 bits: 297.1 E(85289): 2.4e-80
Smith-Waterman score: 1600; 85.8% identity (85.8% similar) in 295 aa overlap (1-295:1-253)
10 20 30 40 50 60
pF1KE9 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
:::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 ADSGISLNALVAATSSLL----RRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHH
70 80 90 100 110
130 140 150 160 170 180
pF1KE9 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVI
:::::::::::::::::::::::::::::::::::
NP_001 LFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQV-------------------------
180 190 200 210
250 260 270 280 290
pF1KE9 ADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------PALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
220 230 240 250
>>NP_006574 (OMIM: 605224) visual pigment-like receptor (337 aa)
initn: 307 init1: 183 opt: 358 Z-score: 408.3 bits: 83.7 E(85289): 5.3e-16
Smith-Waterman score: 427; 27.1% identity (59.9% similar) in 299 aa overlap (11-287:20-315)
10 20 30 40 50
pF1KE9 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPC
:.. : :. :.. .. .. : ... : : :::::
NP_006 MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 HLLVLSLALADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSA
. ....::..: :.: . ...: : : : .: :::... .. ..::: .
NP_006 NAIIINLAVTDIGVSSIGYPMSAASDLYGS---WKFGYAGCQVYAGLNIFFGMASIGLLT
70 80 90 100 110
120 130 140 150 160
pF1KE9 AIAWGRYHHYCTRS---QLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTL
..: :: : . ... :. ..:.: .:... ::: .:..::. : .: :. ::.
NP_006 VVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTI
120 130 140 150 160 170
170 180 190 200 210
pF1KE9 DYSKGDRNFTSFLFTMSFFNFAMPLFITITSY------------SLMEQKLGKSGHLQVN
.. :.::.:.:. .:. .:: .:: . . : : ..:... :..
NP_006 NWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQID
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 TTLPARTL----LLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALG
.: . . :..:.::.:. :.: ..: .: : . .. :.:: : :...
NP_006 VTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVA
240 250 260 270 280 290
280 290
pF1KE9 NEMVCRGI---WQCLSPQKREKDRTK
:. :.. ..: . :
NP_006 NKKFRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI
300 310 320 330
>>NP_150598 (OMIM: 606665) melanopsin isoform 1 [Homo sa (478 aa)
initn: 369 init1: 141 opt: 325 Z-score: 369.8 bits: 77.1 E(85289): 7.4e-14
Smith-Waterman score: 368; 29.1% identity (56.1% similar) in 285 aa overlap (19-271:73-352)
10 20 30 40
pF1KE9 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELR
.: :.:. .:.:. : .:..::.. ::
NP_150 PSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLR
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE9 TPCHLLVLSLALADSGISLN-ALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASI
:: ......::..: .:.. : : :::: ...: .: ::. ..: : . ...:.
NP_150 TPANMFIINLAVSDFLMSFTQAPVFFTSSL----YKQWLFGETGCEFYAFCGALFGISSM
110 120 130 140 150
110 120 130 140 150 160
pF1KE9 CSSAAIAWGRYHHYCTRSQLAWNSA----VSLVLF-VWLSSAFWAALPLLGWGHYDYEPL
. .::: :: :: ... : ...::. ::: . :. :..::. : : :
NP_150 ITLTAIALDRYL-VITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGL
160 170 180 190 200 210
170 180 190 200 210
pF1KE9 GTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGH----------
: :. :: . .. . . : : .::.: : : .. . . ..:.
NP_150 LTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKG
220 230 240 250 260 270
220 230 240 250
pF1KE9 ----------LQVNTTLPARTLL------LGWGPYAILYLYAVIADVTSISPKLQMVPAL
:: . . :: :.:.::. . : : . . ..: .. :::.
NP_150 NGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAV
280 290 300 310 320 330
260 270 280 290
pF1KE9 IAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
::: : : ::.
NP_150 IAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHT
340 350 360 370 380 390
>>XP_016872445 (OMIM: 606665) PREDICTED: melanopsin isof (528 aa)
initn: 369 init1: 141 opt: 325 Z-score: 369.3 bits: 77.2 E(85289): 7.9e-14
Smith-Waterman score: 368; 29.1% identity (56.1% similar) in 285 aa overlap (19-271:73-352)
10 20 30 40
pF1KE9 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELR
.: :.:. .:.:. : .:..::.. ::
XP_016 PSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLR
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE9 TPCHLLVLSLALADSGISLN-ALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASI
:: ......::..: .:.. : : :::: ...: .: ::. ..: : . ...:.
XP_016 TPANMFIINLAVSDFLMSFTQAPVFFTSSL----YKQWLFGETGCEFYAFCGALFGISSM
110 120 130 140 150
110 120 130 140 150 160
pF1KE9 CSSAAIAWGRYHHYCTRSQLAWNSA----VSLVLF-VWLSSAFWAALPLLGWGHYDYEPL
. .::: :: :: ... : ...::. ::: . :. :..::. : : :
XP_016 ITLTAIALDRYL-VITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGL
160 170 180 190 200 210
170 180 190 200 210
pF1KE9 GTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGH----------
: :. :: . .. . . : : .::.: : : .. . . ..:.
XP_016 LTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKG
220 230 240 250 260 270
220 230 240 250
pF1KE9 ----------LQVNTTLPARTLL------LGWGPYAILYLYAVIADVTSISPKLQMVPAL
:: . . :: :.:.::. . : : . . ..: .. :::.
XP_016 NGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAV
280 290 300 310 320 330
260 270 280 290
pF1KE9 IAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
::: : : ::.
XP_016 IAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHT
340 350 360 370 380 390
>>NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] (402 aa)
initn: 320 init1: 215 opt: 301 Z-score: 344.1 bits: 72.1 E(85289): 2e-12
Smith-Waterman score: 333; 26.1% identity (54.8% similar) in 303 aa overlap (12-288:39-336)
10 20 30 40
pF1KE9 MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSF
: : :: ..: .: :.. : :.. .
NP_055 GHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLA--LLLGSIGLLGVGNNLLVLVLY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 CKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFV
: .:::: :::.....:.: .:: ... . : :: . : . . :: ::.: .
NP_055 YKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNG---WVWDTVGCVWDGFSGSL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 TALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEP
...:: . ...:. :: . . .. : . ..:: : ::. :::::..: .
NP_055 FGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYILDV
130 140 150 160 170 180
170 180 190 200 210
pF1KE9 LGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYS--LMEQKLGKSGH----LQV
: ::.:... : : .::.. . . ...:: . :. :. .. . . .::
NP_055 HGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQTIQV
190 200 210 220 230 240
220 230 240 250 260
pF1KE9 NTTLPAR------------TLLLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPT
: . :.:. : :: .. . .: . ..: ...: :.:: .
NP_055 IKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTV
250 260 270 280 290 300
270 280 290
pF1KE9 INAINYALGN--------EMVCRGIWQCLSPQKREKDRTK
: . :.. ...: . .: : :
NP_055 YNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRPKKK
310 320 330 340 350 360
NP_055 VTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
370 380 390 400
>>NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] (354 aa)
initn: 296 init1: 135 opt: 295 Z-score: 338.1 bits: 70.8 E(85289): 4.3e-12
Smith-Waterman score: 350; 26.6% identity (58.7% similar) in 286 aa overlap (17-277:34-315)
10 20 30 40
pF1KE9 MAETSALPTGFGELEVLAVGMVL-LVEALSGLSLNTLTIFSFCKTP
:..:. : .. :: .. . . .: .
NP_859 NHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 ELRTPCHLLVLSLALADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALA
.:: : ......::. : :::. :. ... .:: .: ::. .:. :: . .
NP_859 KLR-PAEIMTINLAVCDLGISV---VGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCG
70 80 90 100 110
110 120 130 140 150 160
pF1KE9 SICSSAAIAWGRYHHYCTRSQLAW---NSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPL
:. . .:.. :: . : : .: . : . .: ..::...::.: : : ::.
NP_859 SLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPF
120 130 140 150 160 170
170 180 190 200 210
pF1KE9 GTCCTLDY--SKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGH--------
:: ::::. .... . :.... :: . .: . . :: . :. .:..
NP_859 GTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSR
180 190 200 210 220 230
220 230 240 250 260
pF1KE9 ------LQVNTTLPARTL----LLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVP
:... : : . :..: :::.. ...... :: .:..::.:.:: .
NP_859 IHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAA
240 250 260 270 280 290
270 280 290
pF1KE9 TINAINY-ALGNEMVCRGIWQCLSPQKREKDRTK
: : : .. ...:
NP_859 MYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE
300 310 320 330 340 350
>>XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 isoform (408 aa)
initn: 296 init1: 135 opt: 295 Z-score: 337.3 bits: 70.9 E(85289): 4.7e-12
Smith-Waterman score: 350; 26.6% identity (58.7% similar) in 286 aa overlap (17-277:34-315)
10 20 30 40
pF1KE9 MAETSALPTGFGELEVLAVGMVL-LVEALSGLSLNTLTIFSFCKTP
:..:. : .. :: .. . . .: .
XP_016 NHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 ELRTPCHLLVLSLALADSGISLNALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALA
.:: : ......::. : :::. :. ... .:: .: ::. .:. :: . .
XP_016 KLR-PAEIMTINLAVCDLGISV---VGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCG
70 80 90 100 110
110 120 130 140 150 160
pF1KE9 SICSSAAIAWGRYHHYCTRSQLAW---NSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPL
:. . .:.. :: . : : .: . : . .: ..::...::.: : : ::.
XP_016 SLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPF
120 130 140 150 160 170
170 180 190 200 210
pF1KE9 GTCCTLDY--SKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGH--------
:: ::::. .... . :.... :: . .: . . :: . :. .:..
XP_016 GTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSR
180 190 200 210 220 230
220 230 240 250 260
pF1KE9 ------LQVNTTLPARTL----LLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVP
:... : : . :..: :::.. ...... :: .:..::.:.:: .
XP_016 IHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAA
240 250 260 270 280 290
270 280 290
pF1KE9 TINAINY-ALGNEMVCRGIWQCLSPQKREKDRTK
: : : .. ...:
XP_016 MYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEDKGRLWH
300 310 320 330 340 350
>>XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 isoform (298 aa)
initn: 332 init1: 135 opt: 288 Z-score: 331.2 bits: 69.3 E(85289): 1e-11
Smith-Waterman score: 343; 27.0% identity (58.7% similar) in 259 aa overlap (43-277:5-259)
20 30 40 50 60 70
pF1KE9 ELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVA
. .:: : ......::. : :::. :.
XP_016 MSSRRKKKLR-PAEIMTINLAVCDLGISV---VG
10 20 30
80 90 100 110 120
pF1KE9 ATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAW---
... .:: .: ::. .:. :: . .:. . .:.. :: . : : .:
XP_016 KPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE9 NSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFF
. : . .: ..::...::.: : : ::.:: ::::. .... . :.... ::
XP_016 KHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFF
100 110 120 130 140 150
190 200 210 220
pF1KE9 NFAMPLFITITSYSLMEQKLGKSGH--------------LQVNTTLPARTL----LLGWG
. .: . . :: . :. .:.. :... : : . :..:
XP_016 CLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWI
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE9 PYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINY-ALGNEMVCRGIWQCLSPQK
:::.. ...... :: .:..::.:.:: . : : : .. ...:
XP_016 PYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKK
220 230 240 250 260 270
290
pF1KE9 REKDRTK
XP_016 KSLEGFRLHTVTTVRKSSAVLEIHEEWE
280 290
295 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:51:48 2016 done: Mon Nov 7 01:51:49 2016
Total Scan time: 7.180 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]