Result of FASTA (omim) for
pFN21AE9523
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9523, 461 aa
1>>>pF1KE9523 461 - 461 aa - 461 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3097+/-0.000495; mu= 17.3467+/- 0.030
mean_var=68.7328+/-14.659, 0's: 0 Z-trim(108.7): 262 B-trim: 661 in 1/49
Lambda= 0.154701
statistics sampled from 16532 (16848) to 16532 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.545), E-opt: 0.2 (0.198), width: 16
Scan time: 6.900
The best scores are: opt bits E(85289)
NP_001258680 (OMIM: 114190) calcitonin gene-relate ( 461) 3157 714.3 1.7e-205
NP_005786 (OMIM: 114190) calcitonin gene-related p ( 461) 3157 714.3 1.7e-205
XP_005246289 (OMIM: 114190) PREDICTED: calcitonin ( 472) 3157 714.3 1.7e-205
XP_005246288 (OMIM: 114190) PREDICTED: calcitonin ( 472) 3157 714.3 1.7e-205
XP_005246291 (OMIM: 114190) PREDICTED: calcitonin ( 472) 3157 714.3 1.7e-205
XP_016858640 (OMIM: 114190) PREDICTED: calcitonin ( 472) 3157 714.3 1.7e-205
NP_001158210 (OMIM: 114131,166710) calcitonin rece ( 474) 1872 427.5 3.7e-119
NP_001733 (OMIM: 114131,166710) calcitonin recepto ( 474) 1872 427.5 3.7e-119
NP_001158209 (OMIM: 114131,166710) calcitonin rece ( 508) 1209 279.6 1.4e-74
NP_001189411 (OMIM: 602034) corticotropin-releasin ( 410) 729 172.4 2e-42
NP_001189404 (OMIM: 602034) corticotropin-releasin ( 438) 723 171.1 5.4e-42
NP_001874 (OMIM: 602034) corticotropin-releasing f ( 411) 722 170.8 6e-42
XP_016867241 (OMIM: 602034) PREDICTED: corticotrop ( 397) 721 170.6 6.8e-42
NP_001189410 (OMIM: 602034) corticotropin-releasin ( 397) 721 170.6 6.8e-42
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447) 710 168.2 4.1e-41
XP_005265494 (OMIM: 192321) PREDICTED: vasoactive ( 456) 709 168.0 4.9e-41
NP_001238811 (OMIM: 192321) vasoactive intestinal ( 416) 703 166.6 1.2e-40
XP_011532381 (OMIM: 192321) PREDICTED: vasoactive ( 416) 703 166.6 1.2e-40
XP_005265495 (OMIM: 192321) PREDICTED: vasoactive ( 416) 703 166.6 1.2e-40
NP_001238814 (OMIM: 192321) vasoactive intestinal ( 430) 703 166.6 1.2e-40
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457) 703 166.6 1.2e-40
NP_001238813 (OMIM: 192321) vasoactive intestinal ( 409) 698 165.5 2.5e-40
XP_005265496 (OMIM: 192321) PREDICTED: vasoactive ( 410) 692 164.1 6.2e-40
XP_011513430 (OMIM: 602034) PREDICTED: corticotrop ( 370) 685 162.6 1.7e-39
NP_001189412 (OMIM: 602034) corticotropin-releasin ( 387) 685 162.6 1.8e-39
XP_011513431 (OMIM: 602034) PREDICTED: corticotrop ( 387) 685 162.6 1.8e-39
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440) 682 161.9 3.1e-39
NP_004373 (OMIM: 122561) corticotropin-releasing f ( 415) 672 159.7 1.4e-38
XP_016860159 (OMIM: 182098) PREDICTED: secretin re ( 435) 656 156.1 1.7e-37
XP_011509923 (OMIM: 182098) PREDICTED: secretin re ( 445) 656 156.1 1.7e-37
XP_016860161 (OMIM: 182098) PREDICTED: secretin re ( 377) 643 153.2 1.1e-36
XP_005249675 (OMIM: 102981) PREDICTED: pituitary a ( 411) 640 152.5 1.9e-36
NP_001138619 (OMIM: 122561) corticotropin-releasin ( 375) 626 149.4 1.6e-35
NP_000155 (OMIM: 137241) gastric inhibitory polype ( 466) 626 149.4 1.9e-35
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468) 625 149.2 2.2e-35
XP_016860160 (OMIM: 182098) PREDICTED: secretin re ( 409) 600 143.6 9.4e-34
NP_001289949 (OMIM: 122561) corticotropin-releasin ( 314) 585 140.2 7.7e-33
NP_001138620 (OMIM: 122561) corticotropin-releasin ( 401) 575 138.0 4.4e-32
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438) 574 137.8 5.6e-32
XP_005249618 (OMIM: 601970) PREDICTED: vasoactive ( 463) 574 137.8 5.8e-32
NP_001295347 (OMIM: 137241) gastric inhibitory pol ( 430) 562 135.1 3.5e-31
XP_006716170 (OMIM: 601970) PREDICTED: vasoactive ( 455) 560 134.7 5e-31
NP_001138618 (OMIM: 122561) corticotropin-releasin ( 444) 532 128.5 3.7e-29
NP_000814 (OMIM: 139191,612781) growth hormone-rel ( 423) 527 127.3 7.8e-29
XP_016867240 (OMIM: 602034) PREDICTED: corticotrop ( 558) 524 126.7 1.6e-28
XP_005263787 (OMIM: 182098) PREDICTED: secretin re ( 262) 518 125.2 2.1e-28
XP_005265401 (OMIM: 125350,156400,168468,215045,60 ( 562) 521 126.1 2.5e-28
NP_000307 (OMIM: 125350,156400,168468,215045,60000 ( 593) 521 126.1 2.6e-28
XP_016862422 (OMIM: 125350,156400,168468,215045,60 ( 593) 521 126.1 2.6e-28
NP_001171673 (OMIM: 125350,156400,168468,215045,60 ( 593) 521 126.1 2.6e-28
>>NP_001258680 (OMIM: 114190) calcitonin gene-related pe (461 aa)
initn: 3157 init1: 3157 opt: 3157 Z-score: 3810.4 bits: 714.3 E(85289): 1.7e-205
Smith-Waterman score: 3157; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)
10 20 30 40 50 60
pF1KE9 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
370 380 390 400 410 420
430 440 450 460
pF1KE9 YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
:::::::::::::::::::::::::::::::::::::::::
NP_001 YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
430 440 450 460
>>NP_005786 (OMIM: 114190) calcitonin gene-related pepti (461 aa)
initn: 3157 init1: 3157 opt: 3157 Z-score: 3810.4 bits: 714.3 E(85289): 1.7e-205
Smith-Waterman score: 3157; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)
10 20 30 40 50 60
pF1KE9 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
370 380 390 400 410 420
430 440 450 460
pF1KE9 YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
:::::::::::::::::::::::::::::::::::::::::
NP_005 YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
430 440 450 460
>>XP_005246289 (OMIM: 114190) PREDICTED: calcitonin gene (472 aa)
initn: 3157 init1: 3157 opt: 3157 Z-score: 3810.3 bits: 714.3 E(85289): 1.7e-205
Smith-Waterman score: 3157; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:12-472)
10 20 30 40
pF1KE9 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECY
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLYSIFHFGLMMEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 QKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 NWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 SCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFW
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 MLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 LLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE9 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE9 FSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
430 440 450 460 470
>>XP_005246288 (OMIM: 114190) PREDICTED: calcitonin gene (472 aa)
initn: 3157 init1: 3157 opt: 3157 Z-score: 3810.3 bits: 714.3 E(85289): 1.7e-205
Smith-Waterman score: 3157; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:12-472)
10 20 30 40
pF1KE9 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECY
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLYSIFHFGLMMEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 QKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 NWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 SCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFW
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 MLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 LLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE9 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE9 FSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
430 440 450 460 470
>>XP_005246291 (OMIM: 114190) PREDICTED: calcitonin gene (472 aa)
initn: 3157 init1: 3157 opt: 3157 Z-score: 3810.3 bits: 714.3 E(85289): 1.7e-205
Smith-Waterman score: 3157; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:12-472)
10 20 30 40
pF1KE9 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECY
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLYSIFHFGLMMEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 QKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 NWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 SCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFW
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 MLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 LLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE9 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE9 FSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
430 440 450 460 470
>>XP_016858640 (OMIM: 114190) PREDICTED: calcitonin gene (472 aa)
initn: 3157 init1: 3157 opt: 3157 Z-score: 3810.3 bits: 714.3 E(85289): 1.7e-205
Smith-Waterman score: 3157; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:12-472)
10 20 30 40
pF1KE9 MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECY
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLYSIFHFGLMMEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 QKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 NWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 SCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFW
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 MLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 LLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE9 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE9 FSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
430 440 450 460 470
>>NP_001158210 (OMIM: 114131,166710) calcitonin receptor (474 aa)
initn: 1851 init1: 1851 opt: 1872 Z-score: 2260.3 bits: 427.5 E(85289): 3.7e-119
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (4-442:8-449)
10 20 30 40 50
pF1KE9 MEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQ
.: ::.: :: : . .: .: . : :.:.: :::.::.
NP_001 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMDAQYKCYD
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 KIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGN
...: : :.:: ::::::::::::.:. ::. :.:.::::: :::::::::: ::. :
NP_001 RMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 WFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLS
::.:: .::::.:::.::. : ::.:.: :.::.:.::.::: .:.:::::: .:.::.
NP_001 WFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 CQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWM
:::.:::::.:.... ::.. ::::. :. : :: .:::::. .:.: :.:.::::::
NP_001 CQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 LCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHL
::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::.: .:::
NP_001 LCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFV
:::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::::::.::
NP_001 LYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 LIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSF
..:::: .:. ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:::... .
NP_001 VFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRW
360 370 380 390 400 410
420 430 440 450 460
pF1KE9 SNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
. . ::: .... : . : .: :
NP_001 GRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
420 430 440 450 460 470
>>NP_001733 (OMIM: 114131,166710) calcitonin receptor is (474 aa)
initn: 1851 init1: 1851 opt: 1872 Z-score: 2260.3 bits: 427.5 E(85289): 3.7e-119
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (4-442:8-449)
10 20 30 40 50
pF1KE9 MEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQ
.: ::.: :: : . .: .: . : :.:.: :::.::.
NP_001 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMDAQYKCYD
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 KIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGN
...: : :.:: ::::::::::::.:. ::. :.:.::::: :::::::::: ::. :
NP_001 RMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 WFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLS
::.:: .::::.:::.::. : ::.:.: :.::.:.::.::: .:.:::::: .:.::.
NP_001 WFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 CQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWM
:::.:::::.:.... ::.. ::::. :. : :: .:::::. .:.: :.:.::::::
NP_001 CQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 LCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHL
::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::.: .:::
NP_001 LCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 LYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFV
:::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::::::.::
NP_001 LYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 LIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSF
..:::: .:. ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:::... .
NP_001 VFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRW
360 370 380 390 400 410
420 430 440 450 460
pF1KE9 SNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
. . ::: .... : . : .: :
NP_001 GRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
420 430 440 450 460 470
>>NP_001158209 (OMIM: 114131,166710) calcitonin receptor (508 aa)
initn: 1201 init1: 1201 opt: 1209 Z-score: 1460.1 bits: 279.6 E(85289): 1.4e-74
Smith-Waterman score: 1830; 55.7% identity (78.7% similar) in 461 aa overlap (4-442:26-483)
10 20 30
pF1KE9 MEKKCTLYFLVL------LPFFMILVTAELEESPEDSI
.: ::.: :: : . .: .: .
NP_001 MQFSGEKISGQRDLQKSKMRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE9 QLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYF
: :.:.: :::.::....: : :.:: ::::::::::::.:. ::. :.:.:::::
NP_001 ---VGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYF
70 80 90 100 110
100 110 120 130 140 150
pF1KE9 QDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLS
:::::::::: ::. : ::.:: .::::.:::.::. : ::.:.: :.::.:.::.::
NP_001 PDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLS
120 130 140 150 160 170
160 170 180 190
pF1KE9 IASLLISLGIFFYFK----------------SLSCQRITLHKNLFFSFVCNSVVTIIHLT
: .:.:::::: .:. ::.:::.:::::.:.... ::.. ::::.
NP_001 IFTLVISLGIFVFFRKLTTIFPLNWKYRKALSLGCQRVTLHKNMFLTYILNSMIIIIHLV
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE9 AVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYY
:. : :: .:::::. .:.: :.:.::::::::::::::::::::::.:::.: :::
NP_001 EVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYY
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE9 FLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVL
.:::::::.:. ::::.:..:.:::::.: .::::::::::. :::.::.::::::::::
NP_001 LLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVL
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE9 ITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQ
.::.. ::.:::..:.:::.::.::::::::.::..:::: .:. ..:::.:: :.:::
NP_001 VTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQ
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE9 GLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSHDC
:..:.::.:: :.:::. ..:.: :.:::... .. . ::: .... : . :
NP_001 GFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYIC
420 430 440 450 460 470
440 450 460
pF1KE9 PSEHLNGKSIHDIENVLLKPENLYN
.: :
NP_001 HQELRNEPANNQGEESAEIIPLNIIEQESSA
480 490 500
>>NP_001189411 (OMIM: 602034) corticotropin-releasing fa (410 aa)
initn: 568 init1: 218 opt: 729 Z-score: 882.5 bits: 172.4 E(85289): 2e-42
Smith-Waterman score: 729; 34.8% identity (65.2% similar) in 359 aa overlap (56-403:29-377)
30 40 50 60 70 80
pF1KE9 ESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQAEG--VYCNRTWDGW-LCWNDVAAGT
: . :: ::: : : :: :::.
NP_001 MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGA
10 20 30 40 50
90 100 110 120 130 140
pF1KE9 ESMQLCPDYFQD--FDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALN
. ::.::. .. .... . : ..:.: ::. ::.::. .: : :.
NP_001 LVERPCPEYFNGVKYNTTRNAYRECLENGTW----ASK---INYSQCEPILDDKRKYDLH
60 70 80 90 100 110
150 160 170 180 190
pF1KE9 L---FYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTA
. .. .:: .:.:.:. .. .:. ..:. : : ..: ::. .:. .:. .. :
NP_001 YRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFL-LQL
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE9 VANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYF
: .. . .: : :. : :.. :.:::. :: :::: ::.. .:. . . :
NP_001 V--DHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLF
180 190 200 210 220
260 270 280 290 300 310
pF1KE9 LGWGFPLIPACIHAIARSLYYNDNCWISSDTHLL--YIIHGPICAALLVNLFFLLNIVRV
.:: .:. ::.. : :..::.... : :: .::: .::.:. ::.::::.
NP_001 IGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRI
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE9 LITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRP-EGKIAEEVYDYIMHILMH
:.:::... .:. : :::.:::.:.::::: ..:. : : ... .. :. .:.
NP_001 LMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE9 FQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSH
:::..::...:::::::.. .:. :....
NP_001 FQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTA
350 360 370 380 390 400
461 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:10:36 2016 done: Sun Nov 6 18:10:38 2016
Total Scan time: 6.900 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]