Result of FASTA (ccds) for
pFN21AE9507
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9507, 325 aa
1>>>pF1KE9507 325 - 325 aa - 325 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5954+/-0.00113; mu= 14.2223+/- 0.066
mean_var=244.7591+/-105.257, 0's: 0 Z-trim(103.4): 273 B-trim: 881 in 2/44
Lambda= 0.081979
statistics sampled from 6959 (7417) to 6959 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.228), width: 16
Scan time: 2.070
The best scores are: opt bits E(32554)
CCDS11868.1 MC5R gene_id:4161|Hs108|chr18 ( 325) 2154 268.9 3.9e-72
CCDS13449.2 MC3R gene_id:4159|Hs108|chr20 ( 323) 1325 170.9 1.3e-42
CCDS11976.1 MC4R gene_id:4160|Hs108|chr18 ( 332) 1318 170.0 2.3e-42
CCDS11869.1 MC2R gene_id:4158|Hs108|chr18 ( 297) 942 125.5 5.3e-29
CCDS56011.1 MC1R gene_id:4157|Hs108|chr16 ( 317) 921 123.1 3e-28
>>CCDS11868.1 MC5R gene_id:4161|Hs108|chr18 (325 aa)
initn: 2154 init1: 2154 opt: 2154 Z-score: 1408.6 bits: 268.9 E(32554): 3.9e-72
Smith-Waterman score: 2154; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KE9 MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ
250 260 270 280 290 300
310 320
pF1KE9 EMRKTFKEIICCRGFRIACSFPRRD
:::::::::::::::::::::::::
CCDS11 EMRKTFKEIICCRGFRIACSFPRRD
310 320
>>CCDS13449.2 MC3R gene_id:4159|Hs108|chr20 (323 aa)
initn: 1280 init1: 891 opt: 1325 Z-score: 878.7 bits: 170.9 E(32554): 1.3e-42
Smith-Waterman score: 1325; 61.2% identity (84.5% similar) in 322 aa overlap (1-317:1-322)
10 20 30 40 50
pF1KE9 MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSP--CEDMGIAVEVFLTLGVISLLENILVI
::.: : .. .: .:..: .:.:: ::.. : ::::.::..:::::::::
CCDS13 MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 GAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVF
:.:.: :::::::::.:::::::::::.:.: ::: : .... .:.. : :..:.::.:
CCDS13 LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 DSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFI
:::::::.:::.:.::::::::::::::::::: :::.:.. ..:..::. : ::.:::
CCDS13 DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE9 LYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSA--RQRTSMQG
.:::: .::.:::.:::::..:. .::.::::.:: ::::::::: :... .:.. :.:
CCDS13 VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE9 AVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYA
:::.:.::::: :::::::::.:...:: : :: . .::: ::.:::::::.::::::
CCDS13 AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
250 260 270 280 290 300
300 310 320
pF1KE9 FRSQEMRKTFKEIIC-CRGFRIACSFPRRD
::: :.:.::.::.: : :. .
CCDS13 FRSLELRNTFREILCGCNGMNLG
310 320
>>CCDS11976.1 MC4R gene_id:4160|Hs108|chr18 (332 aa)
initn: 1297 init1: 1010 opt: 1318 Z-score: 874.1 bits: 170.0 E(32554): 2.3e-42
Smith-Waterman score: 1318; 62.2% identity (84.5% similar) in 328 aa overlap (1-324:9-331)
10 20 30 40
pF1KE9 MNSSFHL---HFLDLNLNATEGNLSGPNVKNKSSPC-EDMGIAVEVFLTLGV
:..:.:: :. ::.:. .: . .. : :.. .. :::.::::
CCDS11 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYS----DGGCYEQLFVSPEVFVTLGV
10 20 30 40 50
50 60 70 80 90 100
pF1KE9 ISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIAD
:::::::::: ::.::::::::::::.:::::::::::.:.. :::.: :::. . :.
CCDS11 ISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTD-TDAQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE9 AFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWA
.:. .::::.::.:: :..::.::::.:::::: ::::::.::.:::..: : ::. :::
CCDS11 SFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE9 FCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSA
:: ::.::.::.:. ::.:::.:::.:: :..:::.::::.:: :.::::.:::...
CCDS11 ACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE9 RQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNS
:: ..:.::.:.:.:.:::.:::::::::: ...::::: :: ::::::.:::::::::
CCDS11 RQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNS
240 250 260 270 280 290
290 300 310 320
pF1KE9 VMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
..::::::.::::.:::::::::: . :.. :
CCDS11 IIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
300 310 320 330
>>CCDS11869.1 MC2R gene_id:4158|Hs108|chr18 (297 aa)
initn: 930 init1: 559 opt: 942 Z-score: 634.2 bits: 125.5 E(32554): 5.3e-29
Smith-Waterman score: 942; 46.5% identity (77.8% similar) in 288 aa overlap (25-312:13-293)
10 20 30 40 50 60
pF1KE9 MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA
:. ..: : . . :.:.:......:::..:. :
CCDS11 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLA
10 20 30 40
70 80 90 100 110 120
pF1KE9 IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS
. :::::..:::::.::::..::: :. . :.: : : : .: .: :...::
CCDS11 VFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY
.. .:...:. :: .::.:::.:::.::::: :.: ::. .... ::.:::: ::.....
CCDS11 LFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIF
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV
:. . ... . :.: :: ... ::.:::::::.:...:..:: :..:.::.:.
CCDS11 SHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLP-------RANMKGAITL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ
:.::::: ::::: ::. :: ::.: ::. .:: :.. .:::::.:.::.::::::
CCDS11 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
230 240 250 260 270 280
310 320
pF1KE9 EMRKTFKEIICCRGFRIACSFPRRD
:.: .::..: :
CCDS11 ELRDAFKKMIFCSRYW
290
>>CCDS56011.1 MC1R gene_id:4157|Hs108|chr16 (317 aa)
initn: 904 init1: 563 opt: 921 Z-score: 620.5 bits: 123.1 E(32554): 3e-28
Smith-Waterman score: 921; 45.9% identity (76.9% similar) in 303 aa overlap (13-312:13-315)
10 20 30 40 50
pF1KE9 MNSSFHLHFLDLNLNATEGNLS--GPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVI
.::.: . : ... .. : ...:. .::.::..::.:: ::.
CCDS56 MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 GAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVF
..:.::.::::::: :.: ::..:.::: :.. :: .: ::. :: : ....:::.
CCDS56 ATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 DSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFI
: . : :...:.: : :::::::..:::::::: :.: :. .:.::. . . .::
CCDS56 DVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE9 LYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASS-ARQRTSMQGA
: . . :.:::. .:.::: :.. ::.::. : :.. :: : . ..: ...::
CCDS56 AYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE9 VTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF
::.:.:::.: .::.::::::::.. ::.. :. ....::..: ::.::...:::::::
CCDS56 VTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF
250 260 270 280 290 300
300 310 320
pF1KE9 RSQEMRKTFKEIICCRGFRIACSFPRRD
.:::.:.:.::.. :
CCDS56 HSQELRRTLKEVLTCSW
310
325 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:44:10 2016 done: Sun Nov 6 13:44:10 2016
Total Scan time: 2.070 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]