Result of FASTA (omim) for
pFN21AE9461
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9461, 481 aa
1>>>pF1KE9461 481 - 481 aa - 481 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4217+/-0.000359; mu= 19.4215+/- 0.023
mean_var=119.4877+/-25.141, 0's: 0 Z-trim(117.8): 321 B-trim: 2952 in 2/49
Lambda= 0.117331
statistics sampled from 29688 (30105) to 29688 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.353), width: 16
Scan time: 10.470
The best scores are: opt bits E(85289)
NP_005293 (OMIM: 602583) prosaposin receptor GPR37 ( 613) 1420 251.7 4.3e-66
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 465 89.8 1.6e-17
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 459 88.9 3.2e-17
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 459 88.9 3.2e-17
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 459 88.9 3.7e-17
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 417 81.7 4.4e-15
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 345 69.5 1.9e-11
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 333 67.5 8e-11
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 319 65.1 4e-10
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 319 65.1 4e-10
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 319 65.1 4e-10
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 307 63.1 1.7e-09
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 262 55.3 2.9e-07
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 262 55.4 3e-07
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 262 55.4 3.1e-07
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389) 262 55.4 3.3e-07
XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B ad ( 402) 262 55.5 3.3e-07
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520) 262 55.6 3.9e-07
XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B ad ( 556) 262 55.6 4.1e-07
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 259 55.0 5e-07
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 252 53.8 1.2e-06
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 252 53.8 1.2e-06
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 244 52.4 2.7e-06
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 242 52.1 3.4e-06
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 242 52.1 3.6e-06
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 242 52.1 3.6e-06
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 242 52.1 3.6e-06
NP_009158 (OMIM: 604838) probable G-protein couple ( 372) 238 51.4 5.3e-06
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 238 51.4 5.5e-06
XP_016864182 (OMIM: 606925) PREDICTED: pyroglutamy ( 190) 233 50.2 6.2e-06
NP_004113 (OMIM: 601898) growth hormone secretagog ( 289) 235 50.7 6.4e-06
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 237 51.3 7e-06
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 237 51.4 7.5e-06
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 232 50.3 1.1e-05
NP_001243212 (OMIM: 131243,157300,616367) endothel ( 202) 226 49.0 1.5e-05
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 228 49.7 1.7e-05
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 228 49.7 1.7e-05
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 228 49.7 1.7e-05
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 228 49.7 1.7e-05
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 228 49.7 1.7e-05
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 228 49.7 1.7e-05
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 226 49.4 2.3e-05
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 226 49.4 2.4e-05
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 224 49.0 2.9e-05
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 224 49.1 3e-05
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 222 48.6 3.4e-05
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 222 48.6 3.4e-05
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 220 48.3 4.5e-05
XP_005263095 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 220 48.4 4.9e-05
NP_001304020 (OMIM: 602001) neuropeptide Y recepto ( 445) 220 48.4 4.9e-05
>>NP_005293 (OMIM: 602583) prosaposin receptor GPR37 pre (613 aa)
initn: 1557 init1: 686 opt: 1420 Z-score: 1307.6 bits: 251.7 E(85289): 4.3e-66
Smith-Waterman score: 1420; 51.1% identity (78.0% similar) in 405 aa overlap (81-481:215-613)
60 70 80 90 100 110
pF1KE9 EEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPDKDGGTPDSGQELRGNLTGAP
: : . : . : . : ::: :.
NP_005 RAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTN--
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE9 GQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILA
.:....::.::.:. ::.:::.: :..:.:..::.:::.::::: :.::..: ::.::
NP_005 -RRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLA
250 260 270 280 290 300
180 190 200 210 220 230
pF1KE9 SLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFH
.::.::::..:::::.:::.:.::. :: : ::. ::..::.:::::::.:::: ::::.
NP_005 NLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFR
310 320 330 340 350 360
240 250 260 270 280
pF1KE9 VATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTL--DSCIM
.::.. . :: :.: :::::::::.. ::.::..: ::..: : . ::.
NP_005 AATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCII
370 380 390 400 410 420
290 300 310 320 330 340
pF1KE9 KPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWR-VRGPPGRKSECRA
: : .::...: :..::..::.::::::::::: :::.::.::: : .: ..:. :.
NP_005 KISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIR--KAEKACTRG
430 440 450 460 470
350 360 370 380 390 400
pF1KE9 SKHE-QCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTF
.:.. : :::.: :::.::..:.:: .:::.::::.::..: ...::.:::..:.:: :
NP_005 NKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLF
480 490 500 510 520 530
410 420 430 440 450 460
pF1KE9 FKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFH
::. .:::::.:.:.:...::..:::::: ::: : . ... .::. ::. : .
NP_005 FKSCVTPVLLFCLCKPFSRAFMECCCCCC-EECIQKSSTVTSDDNDNEYTTELELSPFST
540 550 560 570 580 590
470 480
pF1KE9 KPRESPPLLPLGTPC
:: . .:: :
NP_005 IRREMSTFASVGTHC
600 610
>>NP_001948 (OMIM: 131243,157300,616367) endothelin-1 re (427 aa)
initn: 465 init1: 115 opt: 465 Z-score: 435.7 bits: 89.8 E(85289): 1.6e-17
Smith-Waterman score: 465; 26.2% identity (61.3% similar) in 328 aa overlap (126-435:76-388)
100 110 120 130 140 150
pF1KE9 PDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIV
.: : ... ..: ::.::: ... :.
NP_001 SFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRII
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE9 WHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEIT-----KQRLLGDVSCRAVPFME
... .... :...::::: :.. . . ::: .:. .. . .: :. ::..
NP_001 YQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQ
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE9 VSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLW
::.:.:...::::..::.. :... .:. : ... ::. :. ::.:: . .
NP_001 KSSVGITVLNLCALSVDRYR-AVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGF
170 180 190 200 210 220
280 290 300 310 320
pF1KE9 QLAQEPAPTMGTLD-SCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFT----
.. : : .:... .... : ::... :: :: :::.:.. :
NP_001 VMV--PFEYRGEQHKTCMLNATSKFME-------FYQDVKDWWLFGFYFCMPLVCTAIFY
230 240 250 260 270
330 340 350 360 370 380
pF1KE9 --VTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVA
.::.... : : . . :.: . . .. .:: :.:..:.: .: .. :.
NP_001 TLMTCEMLNRR-NG----SLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKK
280 290 300 310 320 330
390 400 410 420 430
pF1KE9 YLSTELTRQTLDLLG---LINQFS---TFFKGAITPVLLLCICRPLGQAFLDCCCCCCCE
. .:. .. .::. :.. .. . ... :.:. : . . . . : .: ::::
NP_001 TVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQ
340 350 360 370 380 390
440 450 460 470 480
pF1KE9 ECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
NP_001 SKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
400 410 420
>>NP_000106 (OMIM: 131244,277580,600155,600501) endothel (442 aa)
initn: 459 init1: 236 opt: 459 Z-score: 430.0 bits: 88.9 E(85289): 3.2e-17
Smith-Waterman score: 463; 25.6% identity (56.9% similar) in 445 aa overlap (11-435:13-405)
10 20 30 40 50
pF1KE9 MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQ
.:..:: ::::. : .:: ..: . :
NP_000 MQPPPSLCGRALVALVLACGLSRIWG-------------------EERGFPPDRATPLLQ
10 20 30 40
60 70 80 90 100 110
pF1KE9 ----YVPEEWAEYPRPIHPAGLQPTKPLVATSPNPDKDGGTPDSGQELRGNLTGAPGQRL
..: . .:. . . . : : :. :. .:.: ... :
NP_000 TAEIMTPPTKTLWPKGSNASLARSLAP--AEVPKGDRTAGSPPR------TISPPP----
50 60 70 80
120 130 140 150 160 170
pF1KE9 QIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLAL
:.:. . :. : ... .::..::.:: ... :.... .... : ..:::::
NP_000 -CQGPI-EIKETF--KYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLAL
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE9 WDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATS
:.: . . .:: ... .... .: :. :::.. .:.:.:..:::::.:::.. :..
NP_000 GDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYR-AVA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE9 TLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGT-LDSCIMKPSAS
. ... : . .....::: :..::::: . ... :. : :...: .
NP_000 SWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDII--TMDYKGSYLRICLLHPVQK
210 220 230 240 250 260
300 310 320 330 340
pF1KE9 LPESLYSLVMTYQNARMWWYFGCYFCLPILFT------VTCQLVTWRVRGPPGRKSECRA
.... :..:. :: :. :::::. .: .::.. .: : .
NP_000 T-----AFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM----LRKKSGMQIAL--
270 280 290 300 310
350 360 370 380 390
pF1KE9 SKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIV--VAYLSTELTR-------QTLDLLG
. : . . .. .:: :..:.:.: :: .. :. . : ... .: .:: .:
NP_000 NDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIG
320 330 340 350 360 370
400 410 420 430 440 450
pF1KE9 LINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTE
::. : ... :.:. : . . . . : .: :: :
NP_000 -INMAS--LNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDH
380 390 400 410 420
460 470 480
pF1KE9 VSSSIYFHKPRESPPLLPLGTPC
NP_000 GYDNFRSSNKYSSS
430 440
>>NP_001116131 (OMIM: 131244,277580,600155,600501) endot (442 aa)
initn: 459 init1: 236 opt: 459 Z-score: 430.0 bits: 88.9 E(85289): 3.2e-17
Smith-Waterman score: 463; 25.6% identity (56.9% similar) in 445 aa overlap (11-435:13-405)
10 20 30 40 50
pF1KE9 MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQ
.:..:: ::::. : .:: ..: . :
NP_001 MQPPPSLCGRALVALVLACGLSRIWG-------------------EERGFPPDRATPLLQ
10 20 30 40
60 70 80 90 100 110
pF1KE9 ----YVPEEWAEYPRPIHPAGLQPTKPLVATSPNPDKDGGTPDSGQELRGNLTGAPGQRL
..: . .:. . . . : : :. :. .:.: ... :
NP_001 TAEIMTPPTKTLWPKGSNASLARSLAP--AEVPKGDRTAGSPPR------TISPPP----
50 60 70 80
120 130 140 150 160 170
pF1KE9 QIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLAL
:.:. . :. : ... .::..::.:: ... :.... .... : ..:::::
NP_001 -CQGPI-EIKETF--KYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLAL
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE9 WDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATS
:.: . . .:: ... .... .: :. :::.. .:.:.:..:::::.:::.. :..
NP_001 GDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYR-AVA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE9 TLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGT-LDSCIMKPSAS
. ... : . .....::: :..::::: . ... :. : :...: .
NP_001 SWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDII--TMDYKGSYLRICLLHPVQK
210 220 230 240 250 260
300 310 320 330 340
pF1KE9 LPESLYSLVMTYQNARMWWYFGCYFCLPILFT------VTCQLVTWRVRGPPGRKSECRA
.... :..:. :: :. :::::. .: .::.. .: : .
NP_001 T-----AFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM----LRKKSGMQIAL--
270 280 290 300 310
350 360 370 380 390
pF1KE9 SKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIV--VAYLSTELTR-------QTLDLLG
. : . . .. .:: :..:.:.: :: .. :. . : ... .: .:: .:
NP_001 NDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIG
320 330 340 350 360 370
400 410 420 430 440 450
pF1KE9 LINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTE
::. : ... :.:. : . . . . : .: :: :
NP_001 -INMAS--LNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDH
380 390 400 410 420
460 470 480
pF1KE9 VSSSIYFHKPRESPPLLPLGTPC
NP_001 GYDNFRSSNKYSSS
430 440
>>NP_001188326 (OMIM: 131244,277580,600155,600501) endot (532 aa)
initn: 459 init1: 236 opt: 459 Z-score: 429.1 bits: 88.9 E(85289): 3.7e-17
Smith-Waterman score: 463; 25.6% identity (56.9% similar) in 445 aa overlap (11-435:103-495)
10 20 30 40
pF1KE9 MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQ
.:..:: ::::. :
NP_001 EALKLRSGHRTPSGAGSSMQPPPSLCGRALVALVLACGLSRIWG----------------
80 90 100 110
50 60 70 80 90
pF1KE9 QSRSKRGTEDEEAKGVQQ----YVPEEWAEYPRPIHPAGLQPTKPLVATSPNPDKDGGTP
.:: ..: . : ..: . .:. . . . : : :. :. .:.:
NP_001 ---EERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNASLARSLAP--AEVPKGDRTAGSP
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE9 DSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVW
... : :.:. . :. : ... .::..::.:: ... :..
NP_001 PR------TISPPP-----CQGPI-EIKETF--KYINTVVSCLVFVLGIIGNSTLLRIIY
180 190 200 210
160 170 180 190 200 210
pF1KE9 HSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGV
.. .... : ..::::: :.: . . .:: ... .... .: :. :::.. .:.:.
NP_001 KNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGI
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE9 TTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEP
:..:::::.:::.. :... ... : . .....::: :..::::: . ...
NP_001 TVLSLCALSIDRYR-AVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDII--T
280 290 300 310 320 330
280 290 300 310 320
pF1KE9 APTMGT-LDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFT------VTCQ
:. : :...: . .... :..:. :: :. :::::. .: .::.
NP_001 MDYKGSYLRICLLHPVQKT-----AFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCE
340 350 360 370 380
330 340 350 360 370 380
pF1KE9 LVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIV--VAYLST
. .: : . . : . . .. .:: :..:.:.: :: .. :. . : ..
NP_001 M----LRKKSGMQIAL--NDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE9 ELTR-------QTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECG
. .: .:: .: ::. : ... :.:. : . . . . : .: :: :
NP_001 DPNRCELLSFLLVLDYIG-INMAS--LNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEE
450 460 470 480 490 500
450 460 470 480
pF1KE9 GASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
NP_001 KQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
510 520 530
>>NP_003982 (OMIM: 131244,277580,600155,600501) endothel (436 aa)
initn: 433 init1: 236 opt: 417 Z-score: 391.7 bits: 81.7 E(85289): 4.4e-15
Smith-Waterman score: 421; 24.9% identity (56.1% similar) in 437 aa overlap (11-427:13-397)
10 20 30 40 50
pF1KE9 MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQ
.:..:: ::::. : .:: ..: . :
NP_003 MQPPPSLCGRALVALVLACGLSRIWG-------------------EERGFPPDRATPLLQ
10 20 30 40
60 70 80 90 100 110
pF1KE9 ----YVPEEWAEYPRPIHPAGLQPTKPLVATSPNPDKDGGTPDSGQELRGNLTGAPGQRL
..: . .:. . . . : : :. :. .:.: ... : :
NP_003 TAEIMTPPTKTLWPKGSNASLARSLAP--AEVPKGDRTAGSPPR------TISPPPCQG-
50 60 70 80 90
120 130 140 150 160 170
pF1KE9 QIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLAL
:. . : ... .::..::.:: ... :.... .... : ..:::::
NP_003 -------PIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLAL
100 110 120 130 140
180 190 200 210 220 230
pF1KE9 WDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATS
:.: . . .:: ... .... .: :. :::.. .:.:.:..:::::.:::.. :..
NP_003 GDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYR-AVA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE9 TLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGT-LDSCIMKPSAS
. ... : . .....::: :..::::: . ... :. : :...: .
NP_003 SWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIIT--MDYKGSYLRICLLHPVQK
210 220 230 240 250 260
300 310 320 330 340
pF1KE9 LPESLYSLVMTYQNARMWWYFGCYFCLPILFT------VTCQLVTWRVRGPPGRKSECRA
.... :..:. :: :. :::::. .: .::... : : .
NP_003 T-----AFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEML----RKKSGMQIA--L
270 280 290 300 310
350 360 370 380 390
pF1KE9 SKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIV--VAYLSTELTR-------QTLDLLG
. : . . .. .:: :..:.:.: :: .. :. . : ... .: .:: .:
NP_003 NDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIG
320 330 340 350 360 370
400 410 420 430 440 450
pF1KE9 LINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTE
::. : ... :.:. : . . . . :
NP_003 -INMAS--LNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSVNIECDGTVNQNPTMW
380 390 400 410 420
>>NP_005305 (OMIM: 305670) gastrin-releasing peptide rec (384 aa)
initn: 321 init1: 215 opt: 345 Z-score: 326.5 bits: 69.5 E(85289): 1.9e-11
Smith-Waterman score: 348; 24.8% identity (58.2% similar) in 311 aa overlap (131-434:41-340)
110 120 130 140 150 160
pF1KE9 ELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYY
:.: . :.. .:..::.... :
NP_005 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKS
20 30 40 50 60 70
170 180 190 200 210 220
pF1KE9 LKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFS
.... : ...:::: :.:.:. : :. .. . :.: ..:. .::....:.::..:.
NP_005 MRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFT
80 90 100 110 120 130
230 240 250 260 270
pF1KE9 LCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQ-EPAPT
: ::. ::... . . .. . ..: : : ::. :: ::.:: .. .: . :
NP_005 LTALSADRYKAIVRPMD-IQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEEST
140 150 160 170 180
280 290 300 310 320 330
pF1KE9 MGTLDSCIMKP-SASLPESLYSLVMTYQNARMWWYFGCYFCLPI-LFTVTCQLVTWR-VR
:. :: : : : ...:.. : .. .:. ...: ... ..
NP_005 NQTFISCAPYPHSNELHPKIHSMAS----------FLVFYVIPLSIISVYYYFIAKNLIQ
190 200 210 220 230
340 350 360 370 380 390
pF1KE9 GPPGRKSECRASKHEQCESQ--LNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTL
. . : ..: ::. : .::. .. ..::: ::..: . .: .:. . :
NP_005 SAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSML
240 250 260 270 280 290
400 410 420 430 440 450
pF1KE9 DLLGLI-NQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDN
.. : .. .: .. ..: : . . . . : ::
NP_005 HFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMT
300 310 320 330 340 350
460 470 480
pF1KE9 KLKTEVSSSIYFHKPRESPPLLPLGTPC
NP_005 SLKSTNPSVATFSLINGNICHERYV
360 370 380
>>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [ (399 aa)
initn: 215 init1: 215 opt: 333 Z-score: 315.3 bits: 67.5 E(85289): 8e-11
Smith-Waterman score: 336; 23.2% identity (62.5% similar) in 315 aa overlap (132-437:49-351)
110 120 130 140 150 160
pF1KE9 LRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYL
::.. :...:::.:: .. . ... .
NP_001 DTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSM
20 30 40 50 60 70
170 180 190 200 210 220
pF1KE9 KSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSL
... : ...:::. :.:.:. :.:. . ... :.: ..:... :....:.::..:.:
NP_001 QTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTL
80 90 100 110 120 130
230 240 250 260 270
pF1KE9 CALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLA--QEPAPT
:. ::...... : . .: . . .: . .:. :: .:.:: .. .. ..: .
NP_001 TILSADRYKAVVKPLER-QPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKN
140 150 160 170 180 190
280 290 300 310 320 330
pF1KE9 MGTLDSCIMKP-SASLPESLYSLVMTYQNARMWWYFGCYFCLPI-LFTVTCQLVTWRV-R
: :..:: : : .: . ..::. : .. .:. ...: .:.. . .
NP_001 M-TFESCTSYPVSKKLLQEIHSLLC----------FLVFYIIPLSIISVYYSLIARTLYK
200 210 220 230 240
340 350 360 370 380 390
pF1KE9 GPPGRKSECRASKHEQCESQ--LNSTVVGLTVVYAFCTLPENVCNIVVAYLS-TELTRQT
. . .: .. ..: ::. . ::. :....:.: ::... . .. : : . ..
NP_001 STLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSA
250 260 270 280 290 300
400 410 420 430 440 450
pF1KE9 LDLLGLI-NQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSD
. .. : .. .: .. ..: : . . . . : :: :
NP_001 MHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTTLA
310 320 330 340 350 360
460 470 480
pF1KE9 NKLKTEVSSSIYFHKPRESPPLLPLGTPC
NP_001 VMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
370 380 390
>>NP_000900 (OMIM: 162641) neuropeptide Y receptor type (384 aa)
initn: 231 init1: 161 opt: 319 Z-score: 302.7 bits: 65.1 E(85289): 4e-10
Smith-Waterman score: 319; 24.4% identity (59.7% similar) in 315 aa overlap (133-431:40-338)
110 120 130 140 150
pF1KE9 RGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAV---GIVGNLSVMCIVWHSY
:. :::. :: :. :::... :. ..
NP_000 ENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQK
10 20 30 40 50 60
160 170 180 190 200 210
pF1KE9 YLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTF
.... : ....:.. :.:: ..:::... . . ..:.. :. ::.. :. :. :
NP_000 EMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIF
70 80 90 100 110 120
220 230 240 250 260 270
pF1KE9 SLCALGIDRFHVATSTLPK-VRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAP
:: ....: .. . :. :: .: . .::::: ... ..: :. ...::
NP_000 SLVLIAVERHQLIIN--PRGWRPNNRHAYV--GIAVIWVLAVASSLPFLIYQVMTDEPFQ
130 140 150 160 170 180
280 290 300 310 320 330
pF1KE9 TMGTLDS------CIMK-PSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQL-
.. :::. :. . :: : : .:... : ::: :. : : .
NP_000 NV-TLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQ------YFG-----PLCFIFICYFK
190 200 210 220 230
340 350 360 370 380
pF1KE9 VTWRVRGPPGRKSECRASKHEQCESQ-LNSTVVGLTVVYAFCTLPENVCNIVVAYLSTEL
. :.. . .. : .:... :.. .: .....:..: : :: .. : : . .
NP_000 IYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQII
240 250 260 270 280 290
390 400 410 420 430 440
pF1KE9 TRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLG---QAFLDCCCCCCCEECGGASEAS
. . .:: :. ....... ..:.. . . . : :.. :
NP_000 ATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMS
300 310 320 330 340 350
450 460 470 480
pF1KE9 AANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
NP_000 TMHTDVSKTSLKQASPVAFKKINNNDDNEKI
360 370 380
>>XP_005263088 (OMIM: 162641) PREDICTED: neuropeptide Y (384 aa)
initn: 231 init1: 161 opt: 319 Z-score: 302.7 bits: 65.1 E(85289): 4e-10
Smith-Waterman score: 319; 24.4% identity (59.7% similar) in 315 aa overlap (133-431:40-338)
110 120 130 140 150
pF1KE9 RGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAV---GIVGNLSVMCIVWHSY
:. :::. :: :. :::... :. ..
XP_005 ENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQK
10 20 30 40 50 60
160 170 180 190 200 210
pF1KE9 YLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTF
.... : ....:.. :.:: ..:::... . . ..:.. :. ::.. :. :. :
XP_005 EMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIF
70 80 90 100 110 120
220 230 240 250 260 270
pF1KE9 SLCALGIDRFHVATSTLPK-VRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAP
:: ....: .. . :. :: .: . .::::: ... ..: :. ...::
XP_005 SLVLIAVERHQLIIN--PRGWRPNNRHAYV--GIAVIWVLAVASSLPFLIYQVMTDEPFQ
130 140 150 160 170 180
280 290 300 310 320 330
pF1KE9 TMGTLDS------CIMK-PSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQL-
.. :::. :. . :: : : .:... : ::: :. : : .
XP_005 NV-TLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQ------YFG-----PLCFIFICYFK
190 200 210 220 230
340 350 360 370 380
pF1KE9 VTWRVRGPPGRKSECRASKHEQCESQ-LNSTVVGLTVVYAFCTLPENVCNIVVAYLSTEL
. :.. . .. : .:... :.. .: .....:..: : :: .. : : . .
XP_005 IYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQII
240 250 260 270 280 290
390 400 410 420 430 440
pF1KE9 TRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLG---QAFLDCCCCCCCEECGGASEAS
. . .:: :. ....... ..:.. . . . : :.. :
XP_005 ATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMS
300 310 320 330 340 350
450 460 470 480
pF1KE9 AANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
XP_005 TMHTDVSKTSLKQASPVAFKKINNNDDNEKI
360 370 380
481 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:43:35 2016 done: Sun Nov 6 18:43:37 2016
Total Scan time: 10.470 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]