Result of FASTA (omim) for
pFN21AE9448
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9448, 478 aa
1>>>pF1KE9448 478 - 478 aa - 478 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6876+/-0.000357; mu= 12.6542+/- 0.023
mean_var=136.7593+/-29.209, 0's: 0 Z-trim(118.9): 657 B-trim: 3078 in 2/51
Lambda= 0.109672
statistics sampled from 31488 (32291) to 31488 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.379), width: 16
Scan time: 8.250
The best scores are: opt bits E(85289)
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 3243 524.6 2.3e-148
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 3167 512.6 1e-144
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 2599 422.7 1.1e-117
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 2568 417.8 2.9e-116
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 2523 410.7 4.9e-114
NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] ( 354) 547 97.9 4.8e-20
XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 iso ( 408) 547 98.0 5.3e-20
XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 iso ( 298) 514 92.7 1.6e-18
NP_006574 (OMIM: 605224) visual pigment-like recep ( 337) 452 82.9 1.5e-15
NP_000530 (OMIM: 136880,180380,610445,613731) rhod ( 348) 411 76.4 1.4e-13
NP_001699 (OMIM: 190900,613522) short-wave-sensiti ( 348) 395 73.9 8.2e-13
XP_016856350 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
XP_016856351 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
XP_005245114 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
NP_001254539 (OMIM: 612250) G-protein coupled rece ( 529) 396 74.2 9.9e-13
XP_005245113 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
XP_011507678 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
XP_011507677 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
XP_011507679 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
XP_011507680 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
NP_722561 (OMIM: 612250) G-protein coupled recepto ( 529) 396 74.2 9.9e-13
XP_016856349 (OMIM: 612250) PREDICTED: G-protein c ( 529) 396 74.2 9.9e-13
NP_001254540 (OMIM: 612250) G-protein coupled rece ( 546) 396 74.2 1e-12
XP_005245112 (OMIM: 612250) PREDICTED: G-protein c ( 549) 396 74.2 1e-12
XP_016856348 (OMIM: 612250) PREDICTED: G-protein c ( 549) 396 74.2 1e-12
NP_001254538 (OMIM: 612250) G-protein coupled rece ( 549) 396 74.2 1e-12
XP_011507675 (OMIM: 612250) PREDICTED: G-protein c ( 552) 396 74.2 1e-12
XP_011507672 (OMIM: 612250) PREDICTED: G-protein c ( 552) 396 74.2 1e-12
XP_016856347 (OMIM: 612250) PREDICTED: G-protein c ( 552) 396 74.2 1e-12
XP_006711314 (OMIM: 612250) PREDICTED: G-protein c ( 552) 396 74.2 1e-12
XP_011507673 (OMIM: 612250) PREDICTED: G-protein c ( 552) 396 74.2 1e-12
XP_011507674 (OMIM: 612250) PREDICTED: G-protein c ( 552) 396 74.2 1e-12
XP_006711316 (OMIM: 612250) PREDICTED: G-protein c ( 609) 396 74.3 1.1e-12
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] ( 402) 389 73.0 1.8e-12
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 387 72.6 1.9e-12
NP_000504 (OMIM: 300821,303700,303800) medium-wave ( 364) 382 71.8 3.5e-12
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 382 71.9 3.6e-12
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 377 71.1 6.5e-12
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 377 71.1 6.9e-12
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 377 71.1 7e-12
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 377 71.2 7.4e-12
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 374 70.6 8.1e-12
NP_064445 (OMIM: 300822,303700,303900) long-wave-s ( 364) 373 70.4 9.4e-12
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 369 69.7 1.3e-11
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 366 69.3 2e-11
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 364 69.1 2.9e-11
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 361 68.5 3.3e-11
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 361 68.5 3.3e-11
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 361 68.5 3.5e-11
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389) 361 68.5 3.7e-11
>>NP_150598 (OMIM: 606665) melanopsin isoform 1 [Homo sa (478 aa)
initn: 3243 init1: 3243 opt: 3243 Z-score: 2784.6 bits: 524.6 E(85289): 2.3e-148
Smith-Waterman score: 3243; 99.8% identity (99.8% similar) in 478 aa overlap (1-478:1-478)
10 20 30 40 50 60
pF1KE9 MNPPSGPRVLPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 FTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 CFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 CFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 VILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 VILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 IAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 IAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGW
370 380 390 400 410 420
430 440 450 460 470
pF1KE9 THMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKGLIPSQDPRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_150 THMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKGLIPSQDPRM
430 440 450 460 470
>>XP_016872445 (OMIM: 606665) PREDICTED: melanopsin isof (528 aa)
initn: 3191 init1: 3167 opt: 3167 Z-score: 2719.0 bits: 512.6 E(85289): 1e-144
Smith-Waterman score: 3167; 99.4% identity (99.6% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KE9 MNPPSGPRVLPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 CFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 VILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 IAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGW
370 380 390 400 410 420
430 440 450 460 470
pF1KE9 THMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKGLIPSQDPRM
::::::::::::::::::::::::::::::::::::::::::::::. :
XP_016 THMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKVTGPGTCQSTKGWG
430 440 450 460 470 480
XP_016 LGASSPGRGQERETCSHGQGRYPPGITCSQHLPAFPCLPGVLCDSEML
490 500 510 520
>>NP_001025186 (OMIM: 606665) melanopsin isoform 2 [Homo (489 aa)
initn: 2567 init1: 2567 opt: 2599 Z-score: 2233.8 bits: 422.7 E(85289): 1.1e-117
Smith-Waterman score: 3211; 97.5% identity (97.5% similar) in 489 aa overlap (1-478:1-489)
10 20 30 40 50 60
pF1KE9 MNPPSGPRVLPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
10 20 30 40 50 60
70 80 90 100
pF1KE9 PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCR-----------SRSLRTPANMFI
::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE9 YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE9 ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG
430 440 450 460 470 480
470
pF1KE9 LIPSQDPRM
:::::::::
NP_001 LIPSQDPRM
>>XP_016872446 (OMIM: 606665) PREDICTED: melanopsin isof (405 aa)
initn: 2567 init1: 2567 opt: 2568 Z-score: 2208.3 bits: 417.8 E(85289): 2.9e-116
Smith-Waterman score: 2622; 97.3% identity (97.3% similar) in 405 aa overlap (85-478:1-405)
60 70 80 90 100
pF1KE9 AAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCR-----------SRSLRT
::::::::::::: ::::::
XP_016 MLGNLTVIYTFCRAVLRGVTVMMQSRSLRT
10 20 30
110 120 130 140 150 160
pF1KE9 PANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTA
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE9 IALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSW
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE9 DYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLW
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE9 QRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASA
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE9 IHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWI
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE9 SIRRRQESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIRRRQESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAET
340 350 360 370 380 390
470
pF1KE9 PGKTKGLIPSQDPRM
:::::::::::::::
XP_016 PGKTKGLIPSQDPRM
400
>>XP_016872444 (OMIM: 606665) PREDICTED: melanopsin isof (539 aa)
initn: 3178 init1: 2490 opt: 2523 Z-score: 2168.2 bits: 410.7 E(85289): 4.9e-114
Smith-Waterman score: 3135; 97.1% identity (97.3% similar) in 480 aa overlap (1-469:1-480)
10 20 30 40 50 60
pF1KE9 MNPPSGPRVLPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
10 20 30 40 50 60
70 80 90 100
pF1KE9 PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCR-----------SRSLRTPANMFI
::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE9 YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE9 ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::. :
XP_016 ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKVTG
430 440 450 460 470 480
470
pF1KE9 LIPSQDPRM
XP_016 PGTCQSTKGWGLGASSPGRGQERETCSHGQGRYPPGITCSQHLPAFPCLPGVLCDSEML
490 500 510 520 530
>>NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] (354 aa)
initn: 418 init1: 229 opt: 547 Z-score: 480.9 bits: 97.9 E(85289): 4.8e-20
Smith-Waterman score: 547; 30.8% identity (62.0% similar) in 292 aa overlap (69-357:32-313)
40 50 60 70 80 90
pF1KE9 LGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRS
: . : . ..:. . .:: :.: :
NP_859 ALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRR
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE9 RSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSM
.. ::... ::::: :. .: . : . : . ..:.:: ::..:.. : .:: .:.
NP_859 KKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSL
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE9 ITLTAIALDRYLVITRPLATFGVASKRRAAFVLLG-VWLYALAWSLPPFFGWSAYVPEGL
::.::..::::: : ..:: ::. :.. :. .: :: :. :. : . :::: .
NP_859 ITMTAVSLDRYLKICY--LSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPF
130 140 150 160 170
220 230 240 250 260 270
pF1KE9 LTSCSWDYMSFTPAV--RAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGAC
:::. :. .: ... . . : ..:: .:.. :. :. .. ... . : .
NP_859 GTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSR
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE9 KGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVP
... : : :..:. .:. :...: ::..:.. . : . .: ::
NP_859 IHSSHVL--------EMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVP
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE9 AVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTS
...::..:..::::: . :.
NP_859 TLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHE
300 310 320 330 340 350
>>XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 isoform (408 aa)
initn: 418 init1: 229 opt: 547 Z-score: 480.1 bits: 98.0 E(85289): 5.3e-20
Smith-Waterman score: 547; 30.8% identity (62.0% similar) in 292 aa overlap (69-357:32-313)
40 50 60 70 80 90
pF1KE9 LGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRS
: . : . ..:. . .:: :.: :
XP_016 ALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRR
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE9 RSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSM
.. ::... ::::: :. .: . : . : . ..:.:: ::..:.. : .:: .:.
XP_016 KKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSL
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE9 ITLTAIALDRYLVITRPLATFGVASKRRAAFVLLG-VWLYALAWSLPPFFGWSAYVPEGL
::.::..::::: : ..:: ::. :.. :. .: :: :. :. : . :::: .
XP_016 ITMTAVSLDRYLKICY--LSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPF
130 140 150 160 170
220 230 240 250 260 270
pF1KE9 LTSCSWDYMSFTPAV--RAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGAC
:::. :. .: ... . . : ..:: .:.. :. :. .. ... . : .
XP_016 GTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSR
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE9 KGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVP
... : : :..:. .:. :...: ::..:.. . : . .: ::
XP_016 IHSSHVL--------EMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVP
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE9 AVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTS
...::..:..::::: . :.
XP_016 TLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHE
300 310 320 330 340 350
>>XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 isoform (298 aa)
initn: 397 init1: 208 opt: 514 Z-score: 453.7 bits: 92.7 E(85289): 1.6e-18
Smith-Waterman score: 514; 32.2% identity (64.0% similar) in 264 aa overlap (97-357:5-257)
70 80 90 100 110 120
pF1KE9 DHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPV
:...:: ::... ::::: :. .: . :
XP_016 MSSRRKKKLR-PAEIMTINLAVCDLGISVVGKPF
10 20 30
130 140 150 160 170 180
pF1KE9 FFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRR
. : . ..:.:: ::..:.. : .:: .:.::.::..::::: : ..:: ::.
XP_016 TIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKIC--YLSYGVWLKRK
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE9 AAFVLLG-VWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAV--RAYTMLLCCFV
:.. :. .: :: :. :. : . :::: . :::. :. .: ... . . :
XP_016 HAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFC
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE9 FFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVIL
..:: .:.. :. :. .. ... . : . ... : : :..:. .:.
XP_016 LLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVL--------EMKLTKVAMLICA
160 170 180 190 200
310 320 330 340 350 360
pF1KE9 LFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQ
:...: ::..:.. . : . .: ::...::..:..::::: . :.
XP_016 GFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTG
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE9 HLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGWTHM
XP_016 GLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE
270 280 290
>>NP_006574 (OMIM: 605224) visual pigment-like receptor (337 aa)
initn: 498 init1: 225 opt: 452 Z-score: 400.0 bits: 82.9 E(85289): 1.5e-15
Smith-Waterman score: 588; 30.9% identity (66.1% similar) in 298 aa overlap (70-367:25-311)
40 50 60 70 80 90
pF1KE9 GRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSR
: ..: ....:. ....:. :. : . .
NP_006 MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYK
10 20 30 40 50
100 110 120 130 140 150
pF1KE9 SLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMI
::::.: .::::::.:. .: :. .:.:: .: :: .::. :: . .::..:.
NP_006 ELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIG
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE9 TLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLT
::..:.::::.: : . .... ...: :.:. .: :.: :..::..:.:. .
NP_006 LLTVVAVDRYLTICLPDVGRRMTTNTYIGLIL-GAWINGLFWALMPIIGWASYAPDPTGA
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE9 SCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNG
.:. .. . . .::: . . :..:: ...::: . .:.. .: . : .
NP_006 TCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKH-----HTTSDCTESL
180 190 200 210 220
280 290 300 310 320 330
pF1KE9 ESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIA
. :. : ..:. ...: .:...:.::: : : : : . . : :. . ..:
NP_006 NRDWSDQ-----IDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFA
230 240 250 260 270 280
340 350 360 370 380 390
pF1KE9 KASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSN
:.:...:: ::.... :.: :. . :
NP_006 KSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI
290 300 310 320 330
>>NP_000530 (OMIM: 136880,180380,610445,613731) rhodopsi (348 aa)
initn: 518 init1: 208 opt: 411 Z-score: 364.7 bits: 76.4 E(85289): 1.4e-13
Smith-Waterman score: 551; 28.7% identity (67.0% similar) in 300 aa overlap (73-367:40-323)
50 60 70 80 90 100
pF1KE9 PSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLR
:.. ..:. . :. :. ..:. . ..::
NP_000 YVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLR
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE9 TPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLT
:: :....::::.:..: . . .::. ..:: :::.. .: ..: : .. .:.
NP_000 TPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLV
70 80 90 100 110 120
170 180 190 200 210
pF1KE9 AIALDRYLVITRPLATFGVASKRRAAFVLLGV---WLYALAWSLPPFFGWSAYVPEGLLT
..:..::.:. .:...: . .. ...:: :..::: . ::. ::: :.::::
NP_000 VLAIERYVVVCKPMSNFRFGENH----AIMGVAFTWVMALACAAPPLAGWSRYIPEGLQC
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE9 SCSWDYMSFTPAVRAYTMLLCCFV--FFLPLLIIIYCYIFIFRAIRETGRALQTFGACKG
::. ::... : : .... :: : .:..::..:: . ...:.. : .. .
NP_000 SCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQESATTQ-
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE9 NGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAV
..: ........... :.. :.::..::. :. . . : . ..::
NP_000 -----------KAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIFMTIPAF
250 260 270 280 290
340 350 360 370 380 390
pF1KE9 IAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHT
.::..::.::.:: . . ..: . . :
NP_000 FAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTETSQVAPA
300 310 320 330 340
478 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:45:18 2016 done: Sun Nov 6 06:45:20 2016
Total Scan time: 8.250 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]