Result of FASTA (omim) for
pFN21AE9447
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9447, 402 aa
1>>>pF1KE9447 402 - 402 aa - 402 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8128+/-0.000382; mu= 16.2534+/- 0.024
mean_var=125.6370+/-30.633, 0's: 0 Z-trim(115.0): 540 B-trim: 2666 in 2/50
Lambda= 0.114424
statistics sampled from 24557 (25253) to 24557 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.296), width: 16
Scan time: 8.400
The best scores are: opt bits E(85289)
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] ( 402) 2713 459.3 7.5e-129
NP_000530 (OMIM: 136880,180380,610445,613731) rhod ( 348) 596 109.8 1.1e-23
NP_006574 (OMIM: 605224) visual pigment-like recep ( 337) 588 108.4 2.6e-23
NP_001699 (OMIM: 190900,613522) short-wave-sensiti ( 348) 533 99.4 1.5e-20
NP_064445 (OMIM: 300822,303700,303900) long-wave-s ( 364) 523 97.7 4.7e-20
NP_000504 (OMIM: 300821,303700,303800) medium-wave ( 364) 512 95.9 1.7e-19
NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] ( 354) 491 92.4 1.8e-18
XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 iso ( 408) 491 92.5 2e-18
XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 iso ( 298) 472 89.2 1.4e-17
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 404 78.1 4e-14
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 389 75.8 2.6e-13
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 389 75.8 2.8e-13
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 376 73.5 9.9e-13
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 361 71.0 5.6e-12
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 359 70.8 8.1e-12
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 359 70.9 8.6e-12
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 355 70.0 1e-11
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 353 69.8 1.5e-11
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 351 69.4 1.8e-11
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 348 68.9 2.3e-11
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 348 68.9 2.3e-11
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 348 68.9 2.4e-11
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 345 68.3 3e-11
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 339 67.4 7e-11
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 333 66.4 1.3e-10
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 332 66.2 1.5e-10
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 324 64.9 3.7e-10
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 317 63.7 8.1e-10
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 317 63.7 8.1e-10
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 313 63.2 1.5e-09
NP_001012740 (OMIM: 600342,613769) RPE-retinal G p ( 253) 307 61.9 2e-09
NP_001012738 (OMIM: 600342,613769) RPE-retinal G p ( 291) 307 62.0 2.2e-09
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387) 307 62.1 2.7e-09
NP_005949 (OMIM: 600665) melatonin receptor type 1 ( 350) 305 61.7 3.1e-09
NP_002912 (OMIM: 600342,613769) RPE-retinal G prot ( 295) 301 61.0 4.4e-09
XP_016865901 (OMIM: 609042) PREDICTED: opsin-5 iso ( 285) 299 60.6 5.4e-09
XP_016865902 (OMIM: 609042) PREDICTED: opsin-5 iso ( 285) 299 60.6 5.4e-09
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 293 59.8 1.3e-08
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 293 59.8 1.3e-08
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 293 59.8 1.3e-08
NP_001269833 (OMIM: 165196) kappa-type opioid rece ( 291) 289 59.0 1.7e-08
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 288 59.0 2.3e-08
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 288 59.0 2.4e-08
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 288 59.0 2.4e-08
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 288 59.0 2.4e-08
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 288 59.0 2.4e-08
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 288 59.0 2.4e-08
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 288 59.0 2.4e-08
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 288 59.0 2.5e-08
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 288 59.0 2.5e-08
>>NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] (402 aa)
initn: 2713 init1: 2713 opt: 2713 Z-score: 2434.3 bits: 459.3 E(85289): 7.5e-129
Smith-Waterman score: 2713; 100.0% identity (100.0% similar) in 402 aa overlap (1-402:1-402)
10 20 30 40 50 60
pF1KE9 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 GSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 IQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 NTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRP
310 320 330 340 350 360
370 380 390 400
pF1KE9 KKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
::::::::::::::::::::::::::::::::::::::::::
NP_055 KKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
370 380 390 400
>>NP_000530 (OMIM: 136880,180380,610445,613731) rhodopsi (348 aa)
initn: 611 init1: 234 opt: 596 Z-score: 546.4 bits: 109.8 E(85289): 1.1e-23
Smith-Waterman score: 596; 31.6% identity (64.3% similar) in 297 aa overlap (35-325:31-322)
10 20 30 40 50 60
pF1KE9 NRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLV
: : . :: . . .:: :.:.:
NP_000 MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLF
. . ..:::: . .:.:....::.. : : : :. . :.. .:. .:: .:: ..:
NP_000 VTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 GIVSIATLTVLAYERYIRVVHARVINFSW----AWRAITYIWLYSLAWAGAPLLGWNRYI
: ... .:.::: :::. :: . :: . : .... :...:: :. :: ::.:::
NP_000 GEIALWSLVVLAIERYV-VVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYI
130 140 150 160 170
190 200 210 220 230
pF1KE9 LDVHGLGCTVDWKS--KDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDL
. .: .:. . ..:. :::...:. ...:. .: :::.......
NP_000 PEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAA----
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 QTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFA
: . : ::....: ..:...::.::.:: . : . . .: : . . .::
NP_000 QQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIFMTIPAFFA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 KSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGD
:: ..::::::..: ..:: .: .:
NP_000 KSAAIYNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTETSQVAPA
300 310 320 330 340
>>NP_006574 (OMIM: 605224) visual pigment-like receptor (337 aa)
initn: 584 init1: 220 opt: 588 Z-score: 539.4 bits: 108.4 E(85289): 2.6e-23
Smith-Waterman score: 592; 32.0% identity (62.5% similar) in 328 aa overlap (35-354:19-329)
10 20 30 40 50 60
pF1KE9 NRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLV
.:: .. .: : :.... .:..::
NP_006 MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLG
10 20 30 40
70 80 90 100 110 120
pF1KE9 LYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGC-VWDGFSGSL
.. :...:::::. ...:....:. :: .: .. .: : ..: . .:: :. :.. .
NP_006 IFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLN-IF
50 60 70 80 90 100
130 140 150 160 170
pF1KE9 FGIVSIATLTVLAYERYIRV----VHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRY
::..::. :::.: .::. . : :. . .. : :. .: :: :..:: :
NP_006 FGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIG-LILGAWINGLFWALMPIIGWASY
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 ILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLR---CVE
: : ::..:...: . :... .. ..::: :. .:: :. ::. :.:
NP_006 APDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE9 DLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYL
.:. .: ..:: .:: ::: : :: ..:. . : . . : ..:.. :
NP_006 SLNRDWSDQI-----DVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 FAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKD
::::.: ::: ::: .::::..: .. .:: . .:... : :. .::
NP_006 FAKSSTFYNPCIYVVANKKFRRAMLAMF-----KCQTH-QTMPVTS----ILPMDVSQNP
290 300 310 320 330
360 370 380 390 400
pF1KE9 GDRPKKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
NP_006 LASGRI
>>NP_001699 (OMIM: 190900,613522) short-wave-sensitive o (348 aa)
initn: 470 init1: 180 opt: 533 Z-score: 490.2 bits: 99.4 E(85289): 1.5e-20
Smith-Waterman score: 533; 31.0% identity (62.6% similar) in 313 aa overlap (23-325:19-319)
10 20 30 40 50 60
pF1KE9 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNL
:: . ::... . : ..:.. :.: :
NP_001 MRKMSEEEFYLFKNISSVGPWDGPQYHIAPVWA---FYLQAAFMGTVFLIGFPLNA
10 20 30 40 50
70 80 90 100 110
pF1KE9 LVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFV-SCLRNGW-VWDTVGCVWDG
.::: ....:: : . .:::.:.. .:. .:.: .:: :: ::. :. :. .:
NP_001 MVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASC--NGYFVFGRHVCALEG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 FSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWR-AITYI---WLYSLAWAGAPLL
: :.. :.:. .:. ::.:::: :. :: .. . :.: . : ... . :..
NP_001 FLGTVAGLVTGWSLAFLAFERYI-VICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 GWNRYILDVHGLGCTV--DWKSKDAN--DSSFVLFLFLGCLVVPLGVIAHCYGHILYSIR
::.:.: . :: :. :: . .. . :.. :::. :..:::..: : ..: :
NP_001 GWSRFIPE--GLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLL---R
180 190 200 210 220
240 250 260 270 280 290
pF1KE9 MLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTI
:. : : . : :.....: .:. .: ::..:: .. . .::...: . .
NP_001 ALKAVAAQQQ-ESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 SIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPI
. .:.:: .:::.:: :: ..:. .....:
NP_001 VTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSSTQ
290 300 310 320 330 340
360 370 380 390 400
pF1KE9 VMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
NP_001 VGPN
>>NP_064445 (OMIM: 300822,303700,303900) long-wave-sensi (364 aa)
initn: 537 init1: 233 opt: 523 Z-score: 481.0 bits: 97.7 E(85289): 4.7e-20
Smith-Waterman score: 523; 31.5% identity (64.0% similar) in 311 aa overlap (23-324:38-337)
10 20 30 40 50
pF1KE9 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIG
:: . . :: . .:. .. . .
NP_064 QRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRW---VYHLTSVWMIFVV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV
.: .: :::. .::..:: : . .:::....:: .... :...:. . . .:
NP_064 TASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHP
70 80 90 100 110 120
120 130 140 150 160
pF1KE9 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHAR-VINFS--WAWRAITYIWLYSLAWA
:: .:.. :: ::... .:.....::.. : . . :. : .:.. :... .:.
NP_064 MCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 GAPLLGWNRYILDVHGL--GCTVDWKSKDANDS--SFVLFLFLGCLVVPLGVIAHCYGHI
. :..::.:: ::: .: : : .. . :... :.. : ..::..: :: ..
NP_064 APPIFGWSRYW--PHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 LYSIRML-RCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVI-CFLVVNGHG
.:: . . .. .. : : ::....: .:::.. ::: :: . :: ..: :
NP_064 WLAIRAVAKQQKESESTQ-----KAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANP-G
250 260 270 280 290
290 300 310 320 330 340
pF1KE9 HLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGS
. : .. . :::: :.::::::::: :.:: .:::.
NP_064 YAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVS
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE9 EMQIRPIVMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
NP_064 SVSSVSPA
360
>>NP_000504 (OMIM: 300821,303700,303800) medium-wave-sen (364 aa)
initn: 523 init1: 223 opt: 512 Z-score: 471.2 bits: 95.9 E(85289): 1.7e-19
Smith-Waterman score: 512; 30.9% identity (64.3% similar) in 311 aa overlap (23-324:38-337)
10 20 30 40 50
pF1KE9 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIG
:: . . :: . .:. .. . .
NP_000 QRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRW---VYHLTSVWMIFVV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV
. .: .: :::. .::..:: : . .:::....:: .... :.. :. . . .:
NP_000 IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHP
70 80 90 100 110 120
120 130 140 150 160
pF1KE9 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHAR-VINFS--WAWRAITYIWLYSLAWA
:: .:.. :: ::... .:.....::.. : . . :. : .:.. :... .:.
NP_000 MCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 GAPLLGWNRYILDVHGL--GCTVDWKSKDANDS--SFVLFLFLGCLVVPLGVIAHCYGHI
. :..::.:: ::: .: : : .. . :... :.. : ..::..:. :: ..
NP_000 APPIFGWSRYW--PHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 LYSIRML-RCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVI-CFLVVNGHG
.:: . . .. .. : : ::....: .:...: :: :: . :: ..: :
NP_000 WLAIRAVAKQQKESESTQ-----KAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANP-G
250 260 270 280 290
290 300 310 320 330 340
pF1KE9 HLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGS
. : .. . .:::: :.::::::::: :.:: .:::.
NP_000 YPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVS
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE9 EMQIRPIVMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
NP_000 SVSSVSPA
360
>>NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] (354 aa)
initn: 492 init1: 228 opt: 491 Z-score: 452.6 bits: 92.4 E(85289): 1.8e-18
Smith-Waterman score: 491; 30.4% identity (63.0% similar) in 276 aa overlap (51-316:43-313)
30 40 50 60 70 80
pF1KE9 AEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLL
::.:.. .: :: . . .. :....
NP_859 RLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMT
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE9 VNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERY
.:... :: .:. : ::..::. . ::. .:: : :..: .:: :. :.:... .::
NP_859 INLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRY
80 90 100 110 120 130
150 160 170 180 190
pF1KE9 IRVVHARVINFS-WAWRAITYI-----WLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKS
... . .... : : .:: : :. :. ::.: . :. . : .::.::
NP_859 LKICY---LSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWL
140 150 160 170 180
200 210 220 230 240 250
pF1KE9 KDAN--DSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML-RCVEDLQT-IQVIKILKYE
.:. . :.: ... ::..: .::. : .:. ... . : ... :. ..: :
NP_859 AQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVL--E
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE9 KKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYV
::.:. .:. ::. :.:: :. . :. . .:.: :.::: ..:::.::
NP_859 MKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQ
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE9 FMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRPKKKVTFNSSS
. ::
NP_859 VIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE
310 320 330 340 350
>>XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 isoform (408 aa)
initn: 492 init1: 228 opt: 491 Z-score: 451.9 bits: 92.5 E(85289): 2e-18
Smith-Waterman score: 491; 30.4% identity (63.0% similar) in 276 aa overlap (51-316:43-313)
30 40 50 60 70 80
pF1KE9 AEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLL
::.:.. .: :: . . .. :....
XP_016 RLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMT
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE9 VNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERY
.:... :: .:. : ::..::. . ::. .:: : :..: .:: :. :.:... .::
XP_016 INLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRY
80 90 100 110 120 130
150 160 170 180 190
pF1KE9 IRVVHARVINFS-WAWRAITYI-----WLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKS
... . .... : : .:: : :. :. ::.: . :. . : .::.::
XP_016 LKICY---LSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWL
140 150 160 170 180
200 210 220 230 240 250
pF1KE9 KDAN--DSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML-RCVEDLQT-IQVIKILKYE
.:. . :.: ... ::..: .::. : .:. ... . : ... :. ..: :
XP_016 AQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVL--E
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE9 KKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYV
::.:. .:. ::. :.:: :. . :. . .:.: :.::: ..:::.::
XP_016 MKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQ
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE9 FMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRPKKKVTFNSSS
. ::
XP_016 VIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEDKGRLWHQLSCGENS
310 320 330 340 350 360
>>XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 isoform (298 aa)
initn: 468 init1: 204 opt: 472 Z-score: 436.5 bits: 89.2 E(85289): 1.4e-17
Smith-Waterman score: 472; 31.1% identity (63.8% similar) in 257 aa overlap (70-316:7-257)
40 50 60 70 80 90
pF1KE9 TYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTF
..:: :.... .:... :: .:. : ::.
XP_016 MSSRRKKKLR-PAEIMTINLAVCDLGISVVGKPFTI
10 20 30
100 110 120 130 140 150
pF1KE9 VSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFS-WAWRAI
.::. . ::. .:: : :..: .:: :. :.:... .::... . .... : :
XP_016 ISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICY---LSYGVWLKRKH
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE9 TYI-----WLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDAN--DSSFVLFLFLGCL
.:: : :. :. ::.: . :. . : .::.:: .:. . :.: ... ::
XP_016 AYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCL
100 110 120 130 140 150
220 230 240 250 260
pF1KE9 VVPLGVIAHCYGHILYSIRML-RCVEDLQT-IQVIKILKYEKKLAKMCFLMIFTFLVCWM
..: .::. : .:. ... . : ... :. ..: : ::.:. .:. ::. :.
XP_016 LLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVL--EMKLTKVAMLICAGFLIAWI
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE9 PYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLL
:: :. . :. . .:.: :.::: ..:::.:: . ::
XP_016 PYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE9 RCQRPAKDLPAAGSEMQIRPIVMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVDDSDKT
XP_016 KSLEGFRLHTVTTVRKSSAVLEIHEEWE
280 290
>>NP_001040 (OMIM: 182451) somatostatin receptor type 1 (391 aa)
initn: 285 init1: 105 opt: 404 Z-score: 374.5 bits: 78.1 E(85289): 4e-14
Smith-Waterman score: 404; 26.7% identity (58.8% similar) in 330 aa overlap (4-326:26-340)
10 20 30
pF1KE9 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSP
:.:. : : :: : .. . :::: .
NP_001 MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPG-RNASQNGTLSEGQ----
10 20 30 40 50
40 50 60 70 80 90
pF1KE9 GTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFT
:. .... . . :.:. .: .:. . .. ...: :.. ..:....: :. ...: :
NP_001 GSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELL-MLSVPFL
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE9 FVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVH----ARVINFSWA
.: : : . .. : .. ..:: ::::. .::. ::: :: . :
NP_001 VTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 WRAITYIWLYSLAWAGAPLLGWNRYILDVHG-LGCTVDWKSKDAND--SSFVLFLFLGCL
. .:. :: :.. ..: . : ..:.. . :. .:::. :: .
NP_001 KVVNLGVWVLSLLVI-LPIVVFSRTAANSDGTVACNM-LMPEPAQRWLVGFVLYTFLMGF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 VVPLGVIAHCYGHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPY
..:.:.: :: :. ..::. : . . :.:.. : ......:..::::.
NP_001 LLPVGAICLCYVLIIAKMRMVALKAGWQQRK-----RSERKITLMVMMVVMVFVICWMPF
240 250 260 270 280
280 290 300 310 320 330
pF1KE9 IVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRC
:. .:: .. :.: .: ... .:. ::..: :. .:.::. ..:::
NP_001 YVV--QLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDN
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE9 QRPAKDLPAAGSEMQIRPIVMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVDDSDKTNG
NP_001 AAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
350 360 370 380 390
402 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:38:09 2016 done: Sun Nov 6 12:38:10 2016
Total Scan time: 8.400 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]