Result of FASTA (ccds) for
pFN21AE9440
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9440, 345 aa
1>>>pF1KE9440 345 - 345 aa - 345 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2052+/-0.000888; mu= 17.4584+/- 0.053
mean_var=77.0495+/-16.183, 0's: 0 Z-trim(106.7): 31 B-trim: 1124 in 2/47
Lambda= 0.146113
statistics sampled from 9096 (9116) to 9096 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.28), width: 16
Scan time: 2.610
The best scores are: opt bits E(32554)
CCDS8658.1 GPRC5D gene_id:55507|Hs108|chr12 ( 345) 2348 504.4 5.7e-143
CCDS8657.1 GPRC5A gene_id:9052|Hs108|chr12 ( 357) 957 211.2 1.1e-54
CCDS10581.1 GPRC5B gene_id:51704|Hs108|chr16 ( 403) 671 150.9 1.7e-36
CCDS42378.1 GPRC5C gene_id:55890|Hs108|chr17 ( 453) 369 87.3 2.6e-17
CCDS11699.1 GPRC5C gene_id:55890|Hs108|chr17 ( 486) 369 87.3 2.8e-17
>>CCDS8658.1 GPRC5D gene_id:55507|Hs108|chr12 (345 aa)
initn: 2348 init1: 2348 opt: 2348 Z-score: 2680.3 bits: 504.4 E(32554): 5.7e-143
Smith-Waterman score: 2348; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345)
10 20 30 40 50 60
pF1KE9 MYKDCIESTGDYFLLCDAEGPWGIILESLAILGIVVTILLLLAFLFLMRKIQDCSQWNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 MYKDCIESTGDYFLLCDAEGPWGIILESLAILGIVVTILLLLAFLFLMRKIQDCSQWNVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PTQLLFLLSVLGLFGLAFAFIIELNQQTAPVRYFLFGVLFALCFSCLLAHASNLVKLVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 PTQLLFLLSVLGLFGLAFAFIIELNQQTAPVRYFLFGVLFALCFSCLLAHASNLVKLVRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 CVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRGMMFVNMTPCQLNVDFVVLLVYVLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 CVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRGMMFVNMTPCQLNVDFVVLLVYVLFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 MALTFFVSKATFCGPCENWKQHGRLIFITVLFSIIIWVVWISMLLRGNPQFQRQPQWDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 MALTFFVSKATFCGPCENWKQHGRLIFITVLFSIIIWVVWISMLLRGNPQFQRQPQWDDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 VVCIALVTNAWVFLLLYIVPELCILYRSCRQECPLQGNACPVTAYQHSFQVENQELSRAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS86 VVCIALVTNAWVFLLLYIVPELCILYRSCRQECPLQGNACPVTAYQHSFQVENQELSRAR
250 260 270 280 290 300
310 320 330 340
pF1KE9 DSDGAEEDVALTSYGTPIQPQTVDPTQECFIPQAKLSPQQDAGGV
:::::::::::::::::::::::::::::::::::::::::::::
CCDS86 DSDGAEEDVALTSYGTPIQPQTVDPTQECFIPQAKLSPQQDAGGV
310 320 330 340
>>CCDS8657.1 GPRC5A gene_id:9052|Hs108|chr12 (357 aa)
initn: 865 init1: 507 opt: 957 Z-score: 1095.4 bits: 211.2 E(32554): 1.1e-54
Smith-Waterman score: 957; 45.7% identity (74.2% similar) in 337 aa overlap (12-341:17-349)
10 20 30 40 50
pF1KE9 MYKDCIESTGDYFLLCDAEGPWGIILESLAILGIVVTILLLLAFLFLMRKIQDCS
:. ::: :::.::..: :.:... ..:.. .:. :.:: .
CCDS86 MATTVPDGCRNGLKSKYYRLCDKAEAWGIVLETVATAGVVTSVAFMLTLPILVCKVQDSN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 QWNVLPTQLLFLLSVLGLFGLAFAFIIELNQQTAPVRYFLFGVLFALCFSCLLAHASNLV
. ..::::.::::.:::.:::.::::: :. .:.:.:.::::.::..::::::::: .:.
CCDS86 RRKMLPTQFLFLLGVLGIFGLTFAFIIGLDGSTGPTRFFLFGILFSICFSCLLAHAVSLT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 KLVRGCVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRGMM--FVNMTPCQLNVDFVVL
::::: .: .:: .:.: ::.: .:: ::..: :.: . : ... . : :::.:
CCDS86 KLVRGRKPLSLLVILGLAVGFSLVQDVIAIEYIVLTMNRTNVNVFSELSAPRRNEDFVLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE9 LVYVLFLMALTFFVSKATFCGPCENWKQHGRLIFITVLFSIIIWVVWISMLLRGNPQFQR
:.::::::::::..:. :::: .::.:: :..:.:.:: :::.::..:. :.:.:
CCDS86 LTYVLFLMALTFLMSSFTFCGSFTGWKRHGAHIYLTMLLSIAIWVAWITLLML--PDFDR
190 200 210 220 230
240 250 260 270 280 290
pF1KE9 QPQWDDPVVCIALVTNAWVFLLLYIVPELCILYRSCR-QECPLQGNACPVTAYQHSFQVE
. ::: .. ::..:.::::: :. ::. .: .. .. :.. : ..:. ::
CCDS86 R--WDDTILSSALAANGWVFLLAYVSPEFWLLTKQRNPMDYPVEDAFCKPQLVKKSYGVE
240 250 260 270 280 290
300 310 320 330 340
pF1KE9 NQELSRARDSDGAEE--DVALTSYGTPIQPQTVDPTQECFIPQAKL--SPQQDAGGV
:. :. . ..: :: :. . :.: .: :. : .: ::.:. :: .:
CCDS86 NRAYSQEEITQGFEETGDTLYAPYSTHFQLQNQPPQKEFSIPRAHAWPSPYKDYEVKKEG
300 310 320 330 340 350
CCDS86 S
>>CCDS10581.1 GPRC5B gene_id:51704|Hs108|chr16 (403 aa)
initn: 659 init1: 360 opt: 671 Z-score: 768.9 bits: 150.9 E(32554): 1.7e-36
Smith-Waterman score: 671; 35.2% identity (67.3% similar) in 324 aa overlap (3-317:35-351)
10 20 30
pF1KE9 MYKDC-IESTGDYFLLCDAEGPWGIILESLAI
. : .. .: ::: .. :::..:..:
CCDS10 SERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE9 LGIVVTILLLLAFLFLMRKIQDCSQWNVLPTQLLFLLSVLGLFGLAFAFIIELNQQTAPV
: ..:.::.: .: . :.. . . . ..::::..::::::.:::::. .. :
CCDS10 AGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE9 RYFLFGVLFALCFSCLLAHASNLVKLVR-GCVSFSWTTILCIAIGCSLLQIIIATEYVTL
: ::.::::::::::::..: . .::: : .: . .:. :.:.:::.:...:
CCDS10 RRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLV-GLALCLMLVQVIIAVEWLVL
130 140 150 160 170 180
160 170 180 190 200
pF1KE9 IMTRGMMFVNMTP-CQLN-VDFVVLLVYVLFLMALTFFVSKATFCGPCENWKQHGRLIFI
. : . : : . .:::. :.: . :...:. .. :.:: . :: .: ...:
CCDS10 TVLR-----DTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLI
190 200 210 220 230
210 220 230 240 250 260
pF1KE9 TVLFSIIIWVVWISMLLRGNPQFQRQPQWDDPVVCIALVTNAWVFLLLYIVPEL-CILYR
:...:..:::.:..: : :: ..:. :.::.. :.:....:::.... .::. : :
CCDS10 TAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE9 SCRQECPLQGNACPVTAYQHSFQVENQELSRARDSDGA----EEDVALTSYGTPIQPQTV
. ... : .. . .:. :. .: :: . : :...:: . : :
CCDS10 ALQENTPNYFDTSQPRMRETAFE-EDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGK
300 310 320 330 340 350
330 340
pF1KE9 DPTQECFIPQAKLSPQQDAGGV
CCDS10 RPSGSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW
360 370 380 390 400
>>CCDS42378.1 GPRC5C gene_id:55890|Hs108|chr17 (453 aa)
initn: 663 init1: 369 opt: 369 Z-score: 424.1 bits: 87.3 E(32554): 2.6e-17
Smith-Waterman score: 686; 37.2% identity (67.2% similar) in 296 aa overlap (12-295:51-344)
10 20 30 40
pF1KE9 MYKDCIESTGDYFLLCDAEGPWGIILESLAILGIVVTILLL
:. ::: : :::.::..: :::.:..:
CCDS42 MCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLT
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE9 LAFLFLMRKIQDCSQWNVLPTQLLFLLSVLGLFGLAFAFIIELNQQTAPVRYFLFGVLFA
. .. . .:: .. ..: ::..:::..:::: :.:: ... . .: : ::::::::
CCDS42 IILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFA
90 100 110 120 130 140
110 120 130 140 150
pF1KE9 LCFSCLLAHASNLVKLVRGCVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRG------
.::::: ::. : :.: . .:. .:. .:...:: ::.. . ..::
CCDS42 ICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGP
150 160 170 180 190 200
160 170 180 190 200
pF1KE9 -----MMFVNMTPCQL-NVDFVVLLVYVLFLMALTFFVSKATFCGPCENWKQHGRLIFIT
.. .:: . :.:::. :.::..:. .:. . ..:: . :..:: ....:
CCDS42 QGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLT
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE9 VLFSIIIWVVWISMLLRGNPQFQRQPQWDDPVVCIALVTNAWVFLLLYIVPELCILYRSC
. :. :::::: : :: : . .: ::::.. :::..:::.:.:.:..::. . .:
CCDS42 TATSVAIWVVWIVMYTYGNKQ-HNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSS
270 280 290 300 310
270 280 290 300 310 320
pF1KE9 RQECPLQGNACPVTAYQHSFQVENQELSRARDSDGAEEDVALTSYGTPIQPQTVDPTQEC
: ::. :. . . ...:.
CCDS42 -PEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLL
320 330 340 350 360 370
>>CCDS11699.1 GPRC5C gene_id:55890|Hs108|chr17 (486 aa)
initn: 663 init1: 369 opt: 369 Z-score: 423.7 bits: 87.3 E(32554): 2.8e-17
Smith-Waterman score: 686; 37.2% identity (67.2% similar) in 296 aa overlap (12-295:84-377)
10 20 30 40
pF1KE9 MYKDCIESTGDYFLLCDAEGPWGIILESLAILGIVVTILLL
:. ::: : :::.::..: :::.:..:
CCDS11 MCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLT
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE9 LAFLFLMRKIQDCSQWNVLPTQLLFLLSVLGLFGLAFAFIIELNQQTAPVRYFLFGVLFA
. .. . .:: .. ..: ::..:::..:::: :.:: ... . .: : ::::::::
CCDS11 IILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFA
120 130 140 150 160 170
110 120 130 140 150
pF1KE9 LCFSCLLAHASNLVKLVRGCVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRG------
.::::: ::. : :.: . .:. .:. .:...:: ::.. . ..::
CCDS11 ICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGP
180 190 200 210 220 230
160 170 180 190 200
pF1KE9 -----MMFVNMTPCQL-NVDFVVLLVYVLFLMALTFFVSKATFCGPCENWKQHGRLIFIT
.. .:: . :.:::. :.::..:. .:. . ..:: . :..:: ....:
CCDS11 QGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLT
240 250 260 270 280 290
210 220 230 240 250 260
pF1KE9 VLFSIIIWVVWISMLLRGNPQFQRQPQWDDPVVCIALVTNAWVFLLLYIVPELCILYRSC
. :. :::::: : :: : . .: ::::.. :::..:::.:.:.:..::. . .:
CCDS11 TATSVAIWVVWIVMYTYGNKQ-HNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSS
300 310 320 330 340 350
270 280 290 300 310 320
pF1KE9 RQECPLQGNACPVTAYQHSFQVENQELSRARDSDGAEEDVALTSYGTPIQPQTVDPTQEC
: ::. :. . . ...:.
CCDS11 -PEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLL
360 370 380 390 400 410
345 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:55:25 2016 done: Sun Nov 6 14:55:25 2016
Total Scan time: 2.610 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]