Result of FASTA (omim) for
pFN21AE9403
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9403, 494 aa
1>>>pF1KE9403 494 - 494 aa - 494 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6231+/-0.000345; mu= 15.5180+/- 0.022
mean_var=236.3158+/-54.834, 0's: 0 Z-trim(121.3): 229 B-trim: 1969 in 1/55
Lambda= 0.083431
statistics sampled from 37454 (37786) to 37454 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.443), width: 16
Scan time: 11.440
The best scores are: opt bits E(85289)
XP_016877085 (OMIM: 607970) PREDICTED: probable G- ( 494) 3288 408.9 1.7e-113
XP_016877086 (OMIM: 607970) PREDICTED: probable G- ( 494) 3288 408.9 1.7e-113
XP_016877087 (OMIM: 607970) PREDICTED: probable G- ( 494) 3288 408.9 1.7e-113
NP_072093 (OMIM: 607970) probable G-protein couple ( 494) 3288 408.9 1.7e-113
XP_016877088 (OMIM: 607970) PREDICTED: probable G- ( 494) 3288 408.9 1.7e-113
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 353 55.6 3.8e-07
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 353 55.6 4.1e-07
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 335 53.3 1.6e-06
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 328 52.5 2.9e-06
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269) 319 51.1 4.7e-06
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 318 51.3 7e-06
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 318 51.4 7.4e-06
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 316 51.0 7.8e-06
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 310 50.3 1.3e-05
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 304 49.6 2.1e-05
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 295 48.5 4.5e-05
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 295 48.5 4.5e-05
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 295 48.6 5e-05
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 288 47.6 7.6e-05
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 288 47.6 7.6e-05
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 288 47.6 7.6e-05
NP_000530 (OMIM: 136880,180380,610445,613731) rhod ( 348) 287 47.4 7.8e-05
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 285 47.3 0.0001
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 273 45.7 0.00024
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 263 44.6 0.00063
NP_009154 (OMIM: 612183) probable G-protein couple ( 515) 263 44.8 0.00072
XP_016857927 (OMIM: 606916) PREDICTED: probable G- ( 451) 261 44.4 0.00079
NP_114142 (OMIM: 606916) probable G-protein couple ( 451) 261 44.4 0.00079
NP_001258784 (OMIM: 612183) probable G-protein cou ( 470) 253 43.5 0.0016
NP_001041695 (OMIM: 102775) adenosine receptor A1 ( 326) 249 42.8 0.0018
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326) 249 42.8 0.0018
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 249 42.8 0.0019
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 249 42.9 0.002
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 249 42.9 0.002
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 248 42.8 0.0022
NP_997055 (OMIM: 608584,608595) neuropeptide S rec ( 371) 246 42.5 0.0025
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 246 42.5 0.0025
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 246 42.5 0.0025
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 246 42.5 0.0025
NP_997056 (OMIM: 608584,608595) neuropeptide S rec ( 377) 243 42.2 0.0032
NP_001287864 (OMIM: 608584,608595) neuropeptide S ( 390) 243 42.2 0.0033
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 240 41.8 0.0042
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 239 41.7 0.0045
XP_016877362 (OMIM: 612183) PREDICTED: probable G- ( 483) 240 42.0 0.0047
XP_011519469 (OMIM: 612183) PREDICTED: probable G- ( 483) 240 42.0 0.0047
XP_011519470 (OMIM: 612183) PREDICTED: probable G- ( 483) 240 42.0 0.0047
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 237 41.5 0.0058
XP_016873266 (OMIM: 125853,600804) PREDICTED: mela ( 320) 233 40.9 0.0068
NP_005288 (OMIM: 601751) melanin-concentrating hor ( 422) 234 41.2 0.0073
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 233 41.0 0.0076
>>XP_016877085 (OMIM: 607970) PREDICTED: probable G-prot (494 aa)
initn: 3288 init1: 3288 opt: 3288 Z-score: 2158.4 bits: 408.9 E(85289): 1.7e-113
Smith-Waterman score: 3288; 100.0% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KE9 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
430 440 450 460 470 480
490
pF1KE9 VTKQPKSEAGDTSL
::::::::::::::
XP_016 VTKQPKSEAGDTSL
490
>>XP_016877086 (OMIM: 607970) PREDICTED: probable G-prot (494 aa)
initn: 3288 init1: 3288 opt: 3288 Z-score: 2158.4 bits: 408.9 E(85289): 1.7e-113
Smith-Waterman score: 3288; 100.0% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KE9 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
430 440 450 460 470 480
490
pF1KE9 VTKQPKSEAGDTSL
::::::::::::::
XP_016 VTKQPKSEAGDTSL
490
>>XP_016877087 (OMIM: 607970) PREDICTED: probable G-prot (494 aa)
initn: 3288 init1: 3288 opt: 3288 Z-score: 2158.4 bits: 408.9 E(85289): 1.7e-113
Smith-Waterman score: 3288; 100.0% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KE9 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
430 440 450 460 470 480
490
pF1KE9 VTKQPKSEAGDTSL
::::::::::::::
XP_016 VTKQPKSEAGDTSL
490
>>NP_072093 (OMIM: 607970) probable G-protein coupled re (494 aa)
initn: 3288 init1: 3288 opt: 3288 Z-score: 2158.4 bits: 408.9 E(85289): 1.7e-113
Smith-Waterman score: 3288; 100.0% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KE9 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
430 440 450 460 470 480
490
pF1KE9 VTKQPKSEAGDTSL
::::::::::::::
NP_072 VTKQPKSEAGDTSL
490
>>XP_016877088 (OMIM: 607970) PREDICTED: probable G-prot (494 aa)
initn: 3288 init1: 3288 opt: 3288 Z-score: 2158.4 bits: 408.9 E(85289): 1.7e-113
Smith-Waterman score: 3288; 100.0% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KE9 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTA
430 440 450 460 470 480
490
pF1KE9 VTKQPKSEAGDTSL
::::::::::::::
XP_016 VTKQPKSEAGDTSL
490
>>NP_001025186 (OMIM: 606665) melanopsin isoform 2 [Homo (489 aa)
initn: 268 init1: 85 opt: 353 Z-score: 249.2 bits: 55.6 E(85289): 3.8e-07
Smith-Waterman score: 358; 27.5% identity (52.8% similar) in 466 aa overlap (1-436:1-410)
10 20 30 40 50 60
pF1KE9 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
:. :. :: : : .:. . .. .::. .: : :.... :: : . :
NP_001 MNPPSGPRVPPS----PTQEPSCMATPAPPSWWDS-------SQSSISS--LGRLPSIS-
10 20 30 40
70 80 90 100 110 120
pF1KE9 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
.::: . ::. :: .: .: . . :.::. : . ::
NP_001 ---PTAPG------------TWAAAWVPLPTVDVPDHAH----YTLGTVILLVGLTGMLG
50 60 70 80
130 140 150 160
pF1KE9 N-------C-AVM-GVIV--KHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPG
: : ::. :: : . :.::: .: ::..:..::.: .. :. .::
NP_001 NLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPV----FFT---
90 100 110 120 130 140
170 180 190 200 210 220
pF1KE9 GSAPAAAAGPWRGFCAASRFFSSC---FGIVSTLSVALISLDRYCAIVRPPREKIG---R
.. : .. .:.. : ::: : .... :.:::: .:.:: .: .
NP_001 ----SSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRP-LATFGVASK
150 160 170 180 190
230 240 250 260 270 280
pF1KE9 RRALQLLAGAWLTALGFSLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVV
::: .: :.:: ::..::: : .: .: : : : .. : . ..
NP_001 RRAAFVLLGVWLYALAWSLP------PFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTML
200 210 220 230 240
290 300 310 320 330
pF1KE9 AC---YLLPFLLMCFCHYHICKTVRLSDVRVRPVNTYA----------RVLRFFSEVRTA
: ..::.:.. .:. : ...: . : ..:.. . :. :: . :
NP_001 LCCFVFFLPLLIIIYCYIFIFRAIRETG---RALQTFGACKGNGESLWQRQRLQSECKMA
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE9 TTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAVWLTWANGAINPVIYAIR
.:..:.. . :.:: ..:.: : :... .: . :: :: .. :.. ::.::::
NP_001 KIMLLVILLFVLSWAPYSAVALVAFAGYAHVL-TPYMSSVPAV-IAKASAIHNPIIYAIT
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE9 NPNISMLLGRNREEGYRTRNVDAFLPSQGPGLQARSRSRLRNRYANRLGACNRMSSSNPA
.:. . .... .:. :. .. :: : .. .:
NP_001 HPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLG
370 380 390 400 410 420
460 470 480 490
pF1KE9 SGVAGDVAMWARKNPVVLFCREGPPEPVTAVTKQPKSEAGDTSL
NP_001 SESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKGLIPS
430 440 450 460 470 480
>>XP_016872444 (OMIM: 606665) PREDICTED: melanopsin isof (539 aa)
initn: 268 init1: 85 opt: 353 Z-score: 248.8 bits: 55.6 E(85289): 4.1e-07
Smith-Waterman score: 358; 27.5% identity (52.8% similar) in 466 aa overlap (1-436:1-410)
10 20 30 40 50 60
pF1KE9 MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASG
:. :. :: : : .:. . .. .::. .: : :.... :: : . :
XP_016 MNPPSGPRVPPS----PTQEPSCMATPAPPSWWDS-------SQSSISS--LGRLPSIS-
10 20 30 40
70 80 90 100 110 120
pF1KE9 GGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLG
.::: . ::. :: .: .: . . :.::. : . ::
XP_016 ---PTAPG------------TWAAAWVPLPTVDVPDHAH----YTLGTVILLVGLTGMLG
50 60 70 80
130 140 150 160
pF1KE9 N-------C-AVM-GVIV--KHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPG
: : ::. :: : . :.::: .: ::..:..::.: .. :. .::
XP_016 NLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPV----FFT---
90 100 110 120 130 140
170 180 190 200 210 220
pF1KE9 GSAPAAAAGPWRGFCAASRFFSSC---FGIVSTLSVALISLDRYCAIVRPPREKIG---R
.. : .. .:.. : ::: : .... :.:::: .:.:: .: .
XP_016 ----SSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRP-LATFGVASK
150 160 170 180 190
230 240 250 260 270 280
pF1KE9 RRALQLLAGAWLTALGFSLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVV
::: .: :.:: ::..::: : .: .: : : : .. : . ..
XP_016 RRAAFVLLGVWLYALAWSLP------PFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTML
200 210 220 230 240
290 300 310 320 330
pF1KE9 AC---YLLPFLLMCFCHYHICKTVRLSDVRVRPVNTYA----------RVLRFFSEVRTA
: ..::.:.. .:. : ...: . : ..:.. . :. :: . :
XP_016 LCCFVFFLPLLIIIYCYIFIFRAIRETG---RALQTFGACKGNGESLWQRQRLQSECKMA
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE9 TTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAVWLTWANGAINPVIYAIR
.:..:.. . :.:: ..:.: : :... .: . :: :: .. :.. ::.::::
XP_016 KIMLLVILLFVLSWAPYSAVALVAFAGYAHVL-TPYMSSVPAV-IAKASAIHNPIIYAIT
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE9 NPNISMLLGRNREEGYRTRNVDAFLPSQGPGLQARSRSRLRNRYANRLGACNRMSSSNPA
.:. . .... .:. :. .. :: : .. .:
XP_016 HPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLG
370 380 390 400 410 420
460 470 480 490
pF1KE9 SGVAGDVAMWARKNPVVLFCREGPPEPVTAVTKQPKSEAGDTSL
XP_016 SESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKVTGPGTC
430 440 450 460 470 480
>>XP_016872446 (OMIM: 606665) PREDICTED: melanopsin isof (405 aa)
initn: 238 init1: 85 opt: 335 Z-score: 238.3 bits: 53.3 E(85289): 1.6e-06
Smith-Waterman score: 335; 27.7% identity (56.2% similar) in 329 aa overlap (127-436:21-326)
100 110 120 130 140 150
pF1KE9 LSHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLC
:... :.::: .: ::..:..::.: ..
XP_016 MLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQ
10 20 30 40 50
160 170 180 190 200 210
pF1KE9 LPAAFLDLFTPPGGSAPAAAAGPWRGFCAASRFFSSC---FGIVSTLSVALISLDRYCAI
:. .:: .. : .. .:.. : ::: : .... :.:::: .:
XP_016 APV----FFT-------SSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVI
60 70 80 90
220 230 240 250 260 270
pF1KE9 VRPPREKIG---RRRALQLLAGAWLTALGFSLPWELLGAPRELAAAQSFHGCLYRTSPDP
.:: .: .::: .: :.:: ::..::: : .: .: : : :
XP_016 TRP-LATFGVASKRRAAFVLLGVWLYALAWSLP------PFFGWSAYVPEGLLTSCSWDY
100 110 120 130 140 150
280 290 300 310
pF1KE9 AQLGAAFSVGLVVAC---YLLPFLLMCFCHYHICKTVRLSDVRVRPVNTYA---------
.. : . .. : ..::.:.. .:. : ...: . : ..:..
XP_016 MSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETG---RALQTFGACKGNGESL
160 170 180 190 200
320 330 340 350 360 370
pF1KE9 -RVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAVWLTW
. :. :: . : .:..:.. . :.:: ..:.: : :... .: . :: :: ..
XP_016 WQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVL-TPYMSSVPAV-IAK
210 220 230 240 250 260
380 390 400 410 420 430
pF1KE9 ANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGPGLQARSRSRLRNRYANR
:.. ::.:::: .:. . .... .:. :. .. :: : .. .:
XP_016 ASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNL
270 280 290 300 310 320
440 450 460 470 480 490
pF1KE9 LGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTAVTKQPKSEAGDTSL
XP_016 SWISIRRRQESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHE
330 340 350 360 370 380
>>NP_071429 (OMIM: 607448) neuropeptide FF receptor 1 [H (430 aa)
initn: 314 init1: 173 opt: 328 Z-score: 233.5 bits: 52.5 E(85289): 2.9e-06
Smith-Waterman score: 328; 28.1% identity (55.9% similar) in 399 aa overlap (99-474:38-416)
70 80 90 100 110 120
pF1KE9 GGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLL-LIFLLSSLGNCAVMGV
: . :::. .: ::::: .:: : .
NP_071 PPNSSWPLSQNGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFI
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE9 IVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLD-LFTP-PGGSAPAAAAGPWRGFCA
..:.:...:::: :::.:..::::....:.:....: :.: : .: .: .:. .
NP_071 VLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSV
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE9 ASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPWE
.. : : .:. :...:. ::.: :::. :.:: .: : :: . :
NP_071 SA----SVFTLVA------IAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSA
130 140 150 160 170
250 260 270 280 290
pF1KE9 L-LGAPRE----LAAAQS----FHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFC
. : . :: .. :.. ...: ... :. . . .... : :: :. :.
NP_071 VTLTVTREEHHFMVDARNRSYPLYSC-WEAWPEKG-MRRVYTTVLFSHIYLAPLALIVVM
180 190 200 210 220 230
300 310 320 330 340 350
pF1KE9 HYHICKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMI-VFVICCWGPYCFLVLLAA
. .: . . . . : . : : . .. .:.:. .: : : :.::
NP_071 YARIARKLCQAPGPA-PGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLID
240 250 260 270 280 290
360 370 380 390 400
pF1KE9 ARQAQTMQAPSL--LSVVAV----WLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTR
: ..::.: ..: : ::.. :.. ::.::. : :. :. . ..:.:
NP_071 YGQ---LSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFR----RGFQAAFRAR
300 310 320 330 340
410 420 430 440 450 460
pF1KE9 NVDAFLPSQGPGLQARSRSRLRNRY--ANRLGACNRMSSSNPASGVAGDVAMWARKNPVV
:. . . : . :. : . : . . : :.:.::. . :.. :.
NP_071 LCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSDSGLPSESGPSSGAPRPGRLPLRNGRVA
350 360 370 380 390 400
470 480 490
pF1KE9 L--FCREGPPEPVTAVTKQPKSEAGDTSL
. ::::
NP_071 HHGLPREGPGCSHLPLTIPAWDI
410 420 430
>>XP_016881180 (OMIM: 600377) PREDICTED: galanin recepto (269 aa)
initn: 214 init1: 95 opt: 319 Z-score: 229.7 bits: 51.1 E(85289): 4.7e-06
Smith-Waterman score: 319; 32.8% identity (58.6% similar) in 232 aa overlap (76-300:6-223)
50 60 70 80 90 100
pF1KE9 TVATAALGNLSDASGGGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAA
: :..:. .: .:: .::.. :. .
XP_016 MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFV
10 20 30
110 120 130 140 150 160
pF1KE9 QALVLLLIFLLSSLGNCAVMGVIVKHR--QLRTVTNAFILSLSLSDLLTALLCLPAAFLD
.:. ::: :. ::: :. :... . . :..:: :::.::..:: :.:.:
XP_016 TLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIP-----
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE9 LFTPPGGSAPAAAAGPWRGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGR
: . :. . : . .: ..: . .:: ...: .:.::: :::. : . :
XP_016 -FQATVYALPTWVLGAF--ICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLR
100 110 120 130 140
230 240 250 260 270
pF1KE9 --RRALQLLAGAWLTALGFSLPWEL---LGAPRELAAAQSFHGCLYRTSPDPAQLGAAFS
: :: .. : ..... : : :: :. :.: : .. ::: . :.
XP_016 VSRNALLGVGCIWALSIAMASPVAYHQGLFHPR--ASNQTF--C-WEQWPDPRH-KKAYV
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE9 VGLVVACYLLPFLLMCFCHYHICKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIV
: : ::::.::.:::. ..
XP_016 VCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKVQGASFGWIYHSGVWRM
210 220 230 240 250 260
494 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:54:15 2016 done: Mon Nov 7 03:54:17 2016
Total Scan time: 11.440 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]