Result of FASTA (omim) for
pFN21AE9282
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9282, 1249 aa
1>>>pF1KE9282 1249 - 1249 aa - 1249 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3427+/-0.000461; mu= 17.8029+/- 0.029
mean_var=86.7443+/-17.485, 0's: 0 Z-trim(110.9): 59 B-trim: 579 in 1/48
Lambda= 0.137706
statistics sampled from 19296 (19355) to 19296 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.227), width: 16
Scan time: 11.560
The best scores are: opt bits E(85289)
NP_114432 (OMIM: 114480,189960,605882,609054) Fanc (1249) 8292 1658.4 0
XP_011523637 (OMIM: 114480,189960,605882,609054) P (1249) 8128 1625.8 0
XP_016880689 (OMIM: 114480,189960,605882,609054) P (1088) 7152 1431.9 0
XP_011523642 (OMIM: 114480,189960,605882,609054) P ( 853) 4328 870.8 0
XP_011523641 (OMIM: 114480,189960,605882,609054) P ( 872) 4328 870.8 0
XP_011523643 (OMIM: 114480,189960,605882,609054) P ( 657) 4324 869.9 0
XP_011523636 (OMIM: 114480,189960,605882,609054) P (1269) 4328 870.9 0
XP_011523634 (OMIM: 114480,189960,605882,609054) P (1269) 4328 870.9 0
XP_011523635 (OMIM: 114480,189960,605882,609054) P (1269) 4328 870.9 0
XP_011523638 (OMIM: 114480,189960,605882,609054) P (1229) 4324 870.1 0
XP_011523639 (OMIM: 114480,189960,605882,609054) P (1202) 4041 813.8 0
XP_016880690 (OMIM: 114480,189960,605882,609054) P (1088) 3997 805.1 0
XP_011523640 (OMIM: 114480,189960,605882,609054) P (1108) 3997 805.1 0
XP_016880691 (OMIM: 114480,189960,605882,609054) P ( 631) 3968 799.2 0
XP_016880692 (OMIM: 114480,189960,605882,609054) P ( 631) 3968 799.2 0
NP_057518 (OMIM: 608833,615190,616373) regulator o (1219) 940 197.8 3.8e-49
NP_001269938 (OMIM: 608833,615190,616373) regulato (1300) 940 197.8 4e-49
NP_116575 (OMIM: 608833,615190,616373) regulator o (1243) 853 180.5 6.2e-44
NP_001269939 (OMIM: 608833,615190,616373) regulato ( 996) 838 177.5 4e-43
XP_016881956 (OMIM: 126340,278730,601675,610756) P ( 719) 589 127.9 2.3e-28
XP_011524913 (OMIM: 126340,278730,601675,610756) P ( 734) 589 127.9 2.4e-28
NP_000391 (OMIM: 126340,278730,601675,610756) TFII ( 760) 589 127.9 2.5e-28
XP_016874428 (OMIM: 601150,613398) PREDICTED: prob ( 743) 388 88.0 2.5e-16
XP_016874427 (OMIM: 601150,613398) PREDICTED: prob ( 746) 388 88.0 2.5e-16
XP_011518897 (OMIM: 601150,613398) PREDICTED: prob ( 892) 380 86.5 9e-16
XP_005253390 (OMIM: 601150,613398) PREDICTED: prob ( 942) 380 86.5 9.4e-16
XP_006719113 (OMIM: 601150,613398) PREDICTED: prob ( 967) 380 86.5 9.6e-16
XP_005253388 (OMIM: 601150,613398) PREDICTED: prob (1006) 380 86.5 9.9e-16
XP_011518894 (OMIM: 601150,613398) PREDICTED: prob (1031) 380 86.5 1e-15
XP_016874423 (OMIM: 601150,613398) PREDICTED: prob ( 831) 378 86.0 1.1e-15
NP_004390 (OMIM: 601150,613398) probable ATP-depen ( 856) 378 86.1 1.1e-15
XP_016874421 (OMIM: 601150,613398) PREDICTED: prob ( 906) 378 86.1 1.2e-15
NP_085911 (OMIM: 601150,613398) probable ATP-depen ( 906) 378 86.1 1.2e-15
XP_016874420 (OMIM: 601150,613398) PREDICTED: prob ( 931) 378 86.1 1.2e-15
NP_689651 (OMIM: 601150,613398) probable ATP-depen ( 970) 378 86.1 1.3e-15
NP_001244073 (OMIM: 601150,613398) probable ATP-de ( 970) 378 86.1 1.3e-15
XP_011518899 (OMIM: 601150,613398) PREDICTED: prob ( 672) 370 84.4 2.8e-15
XP_016874419 (OMIM: 601150,613398) PREDICTED: prob (1002) 364 83.3 9e-15
XP_016874418 (OMIM: 601150,613398) PREDICTED: prob (1014) 364 83.3 9.1e-15
XP_016874417 (OMIM: 601150,613398) PREDICTED: prob (1027) 364 83.3 9.2e-15
XP_016874416 (OMIM: 601150,613398) PREDICTED: prob (1041) 364 83.3 9.3e-15
XP_016874415 (OMIM: 601150,613398) PREDICTED: prob (1044) 364 83.3 9.3e-15
XP_016874410 (OMIM: 601150,613398) PREDICTED: prob (1066) 364 83.3 9.5e-15
XP_016874409 (OMIM: 601150,613398) PREDICTED: prob (1078) 364 83.3 9.6e-15
XP_016874407 (OMIM: 601150,613398) PREDICTED: prob (1091) 364 83.3 9.7e-15
XP_016874408 (OMIM: 601150,613398) PREDICTED: prob (1091) 364 83.3 9.7e-15
XP_016874413 (OMIM: 601150,613398) PREDICTED: prob (1055) 362 82.9 1.2e-14
XP_016874412 (OMIM: 601150,613398) PREDICTED: prob (1055) 362 82.9 1.2e-14
XP_016874414 (OMIM: 601150,613398) PREDICTED: prob (1055) 362 82.9 1.2e-14
XP_016874411 (OMIM: 601150,613398) PREDICTED: prob (1055) 362 82.9 1.2e-14
>>NP_114432 (OMIM: 114480,189960,605882,609054) Fanconi (1249 aa)
initn: 8292 init1: 8292 opt: 8292 Z-score: 8896.9 bits: 1658.4 E(85289): 0
Smith-Waterman score: 8292; 99.9% identity (99.9% similar) in 1249 aa overlap (1-1249:1-1249)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 CATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 CATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 KTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 KTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 TIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 TIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 ALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 ALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 NIQDNESTLEVTSLKYSTPPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPS
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_114 NIQDNESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 SIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 SIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKAT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 PELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 PELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKID
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 ATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 ATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 DTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 DTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240
pF1KE9 IEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSKNKGMFPGFK
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 IEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSKNKGMFPGFK
1210 1220 1230 1240
>>XP_011523637 (OMIM: 114480,189960,605882,609054) PREDI (1249 aa)
initn: 8128 init1: 8128 opt: 8128 Z-score: 8720.9 bits: 1625.8 E(85289): 0
Smith-Waterman score: 8128; 98.3% identity (99.0% similar) in 1249 aa overlap (1-1249:1-1249)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNL
:::::::::::::::::::::::::::::::::::::::::::::. . . .
XP_011 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQIMSSKFIIYVVACAR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 CATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELV
....:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLKNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 KTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 TIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 ALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 NIQDNESTLEVTSLKYSTPPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPS
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 NIQDNESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 SIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKAT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 PELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKID
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 ATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 DTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240
pF1KE9 IEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSKNKGMFPGFK
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSKNKGMFPGFK
1210 1220 1230 1240
>>XP_016880689 (OMIM: 114480,189960,605882,609054) PREDI (1088 aa)
initn: 7152 init1: 7152 opt: 7152 Z-score: 7673.9 bits: 1431.9 E(85289): 0
Smith-Waterman score: 7152; 99.8% identity (99.9% similar) in 1081 aa overlap (169-1249:8-1088)
140 150 160 170 180 190
pF1KE9 SAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEVHNLDAKVDSGKTVKLNSP
.:::::::::::::::::::::::::::::
XP_016 MALHQLVKIRKRHCFGTEVHNLDAKVDSGKTVKLNSP
10 20 30
200 210 220 230 240 250
pF1KE9 LEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQ
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE9 ITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHK
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE9 ISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADIIFCPYNYLLDAQIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQDADIIFCPYNYLLDAQIR
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE9 ESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRKKDHEPL
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE9 RAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVL
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE9 QKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRFADDYKIAIQQTYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRFADDYKIAIQQTYSW
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE9 TNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLS
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE9 PMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGA
460 470 480 490 500 510
680 690 700 710 720 730
pF1KE9 LLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDEL
520 530 540 550 560 570
740 750 760 770 780 790
pF1KE9 LQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKR
580 590 600 610 620 630
800 810 820 830 840 850
pF1KE9 QYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYIS
640 650 660 670 680 690
860 870 880 890 900 910
pF1KE9 GLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQDNESTLEVTSLKYST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRTNIQDNESTLEVTSLKYST
700 710 720 730 740 750
920 930 940 950 960 970
pF1KE9 PPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAG
760 770 780 790 800 810
980 990 1000 1010 1020 1030
pF1KE9 KAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKT
820 830 840 850 860 870
1040 1050 1060 1070 1080 1090
pF1KE9 EKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEA
880 890 900 910 920 930
1100 1110 1120 1130 1140 1150
pF1KE9 LDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRL
940 950 960 970 980 990
1160 1170 1180 1190 1200 1210
pF1KE9 ANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILHIEESKIDDIDGNVKTTWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILHIEESKIDDIDGNVKTTWI
1000 1010 1020 1030 1040 1050
1220 1230 1240
pF1KE9 NELELGKTHEIEIKNFKPSPSKNKGMFPGFK
:::::::::::::::::::::::::::::::
XP_016 NELELGKTHEIEIKNFKPSPSKNKGMFPGFK
1060 1070 1080
>>XP_011523642 (OMIM: 114480,189960,605882,609054) PREDI (853 aa)
initn: 4388 init1: 4328 opt: 4328 Z-score: 4643.4 bits: 870.8 E(85289): 0
Smith-Waterman score: 5523; 97.6% identity (97.6% similar) in 851 aa overlap (1-831:1-851)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQ---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQIMSSKFIIYVVACAR
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE9 -----VWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLKVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE9 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE9 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE9 AYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALES
:::::::::::
XP_011 AYRALNQALGRTF
850
>>XP_011523641 (OMIM: 114480,189960,605882,609054) PREDI (872 aa)
initn: 4358 init1: 4328 opt: 4328 Z-score: 4643.3 bits: 870.8 E(85289): 0
Smith-Waterman score: 5262; 97.4% identity (97.5% similar) in 814 aa overlap (1-794:1-814)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQ---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQIMSSKFIIYVVACAR
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE9 -----VWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLKVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE9 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE9 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
:::::::::::::::::::::::::::::::::.
XP_011 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQLTSATAEGTNGYAQSWVSYSKMADAAL
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE9 AYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALES
XP_011 TTATDETVDIYPRNLLSPSTALVLHSTEVECY
850 860 870
>>XP_011523643 (OMIM: 114480,189960,605882,609054) PREDI (657 aa)
initn: 4324 init1: 4324 opt: 4324 Z-score: 4640.9 bits: 869.9 E(85289): 0
Smith-Waterman score: 4324; 100.0% identity (100.0% similar) in 645 aa overlap (1-645:1-645)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNL
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQSVPAEKCDYEQQ
610 620 630 640 650
670 680 690 700 710 720
pF1KE9 CATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELV
>>XP_011523636 (OMIM: 114480,189960,605882,609054) PREDI (1269 aa)
initn: 4328 init1: 4328 opt: 4328 Z-score: 4640.7 bits: 870.9 E(85289): 0
Smith-Waterman score: 8242; 98.3% identity (98.3% similar) in 1269 aa overlap (1-1249:1-1269)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQ---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQIMSSKFIIYVVACAR
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE9 -----VWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLKVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE9 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE9 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE9 AYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALES
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE9 LAEFSKKHQKVLNVSIKDRTNIQDNESTLEVTSLKYSTPPYLLEAASHLSPENFVEDEAK
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 LAEFSKKHQKVLNVSIKDRTNIQDNESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAK
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE9 ICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRV
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE9 SWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTV
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE9 NTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRD
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE9 FETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVD
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE9 SAREVKAEDCIDTKLNGILHIEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAREVKAEDCIDTKLNGILHIEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSK
1210 1220 1230 1240 1250 1260
pF1KE9 NKGMFPGFK
:::::::::
XP_011 NKGMFPGFK
>>XP_011523634 (OMIM: 114480,189960,605882,609054) PREDI (1269 aa)
initn: 4328 init1: 4328 opt: 4328 Z-score: 4640.7 bits: 870.9 E(85289): 0
Smith-Waterman score: 8242; 98.3% identity (98.3% similar) in 1269 aa overlap (1-1249:1-1269)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQ---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQIMSSKFIIYVVACAR
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE9 -----VWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLKVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE9 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE9 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE9 AYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALES
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE9 LAEFSKKHQKVLNVSIKDRTNIQDNESTLEVTSLKYSTPPYLLEAASHLSPENFVEDEAK
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 LAEFSKKHQKVLNVSIKDRTNIQDNESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAK
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE9 ICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRV
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE9 SWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTV
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE9 NTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRD
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE9 FETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVD
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE9 SAREVKAEDCIDTKLNGILHIEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAREVKAEDCIDTKLNGILHIEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSK
1210 1220 1230 1240 1250 1260
pF1KE9 NKGMFPGFK
:::::::::
XP_011 NKGMFPGFK
>>XP_011523635 (OMIM: 114480,189960,605882,609054) PREDI (1269 aa)
initn: 4328 init1: 4328 opt: 4328 Z-score: 4640.7 bits: 870.9 E(85289): 0
Smith-Waterman score: 8242; 98.3% identity (98.3% similar) in 1269 aa overlap (1-1249:1-1269)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQ---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQIMSSKFIIYVVACAR
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE9 -----VWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLKVWVGTIGSGPKGRNLCATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE9 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAV
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE9 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQ
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE9 AYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALES
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE9 LAEFSKKHQKVLNVSIKDRTNIQDNESTLEVTSLKYSTPPYLLEAASHLSPENFVEDEAK
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 LAEFSKKHQKVLNVSIKDRTNIQDNESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAK
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE9 ICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICVQELQCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRV
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE9 SWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWSSFNSLGQYFTGKIPKATPELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTV
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE9 NTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTSFGSCPQSETIISSLKIDATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRD
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE9 FETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FETEAEDESIYFTPELYDPEDTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVD
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE9 SAREVKAEDCIDTKLNGILHIEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAREVKAEDCIDTKLNGILHIEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSK
1210 1220 1230 1240 1250 1260
pF1KE9 NKGMFPGFK
:::::::::
XP_011 NKGMFPGFK
>>XP_011523638 (OMIM: 114480,189960,605882,609054) PREDI (1229 aa)
initn: 4324 init1: 4324 opt: 4324 Z-score: 4636.6 bits: 870.1 E(85289): 0
Smith-Waterman score: 8097; 98.3% identity (98.3% similar) in 1249 aa overlap (1-1249:1-1229)
10 20 30 40 50 60
pF1KE9 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNL
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQ---------------
610 620 630 640
670 680 690 700 710 720
pF1KE9 CATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -----NTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELV
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE9 KTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVI
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE9 TIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWG
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE9 ALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRT
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE9 NIQDNESTLEVTSLKYSTPPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPS
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 NIQDNESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPS
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE9 SIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKAT
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE9 PELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKID
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE9 ATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPE
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE9 DTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILH
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240
pF1KE9 IEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSKNKGMFPGFK
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSKNKGMFPGFK
1190 1200 1210 1220
1249 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:19:04 2016 done: Tue Nov 8 10:19:06 2016
Total Scan time: 11.560 Total Display time: 0.520
Function used was FASTA [36.3.4 Apr, 2011]