Result of FASTA (omim) for
pFN21AE9254
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9254, 748 aa
1>>>pF1KE9254 748 - 748 aa - 748 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2967+/-0.000352; mu= 11.9296+/- 0.022
mean_var=128.3554+/-25.693, 0's: 0 Z-trim(118.7): 12 B-trim: 734 in 1/54
Lambda= 0.113205
statistics sampled from 31829 (31841) to 31829 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.373), width: 16
Scan time: 13.580
The best scores are: opt bits E(85289)
NP_060880 (OMIM: 612667) Holliday junction recogni ( 748) 5033 833.5 0
XP_011509739 (OMIM: 612667) PREDICTED: Holliday ju ( 636) 4150 689.3 1.3e-197
NP_001269891 (OMIM: 612667) Holliday junction reco ( 694) 4149 689.1 1.6e-197
NP_001269892 (OMIM: 612667) Holliday junction reco ( 663) 3948 656.3 1.2e-187
>>NP_060880 (OMIM: 612667) Holliday junction recognition (748 aa)
initn: 5033 init1: 5033 opt: 5033 Z-score: 4447.0 bits: 833.5 E(85289): 0
Smith-Waterman score: 5033; 100.0% identity (100.0% similar) in 748 aa overlap (1-748:1-748)
10 20 30 40 50 60
pF1KE9 MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 QGLRIWGGRLIKERNEGEIQDSSMKPADRTDGSVQAAAWGPELPSHRTVLGADSKSGEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QGLRIWGGRLIKERNEGEIQDSSMKPADRTDGSVQAAAWGPELPSHRTVLGADSKSGEVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ATSDQEESVAWALAPAVPQSPLKNELRRKYLTQVDILLQGAEYFECAGNRAGRDVRVTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ATSDQEESVAWALAPAVPQSPLKNELRRKYLTQVDILLQGAEYFECAGNRAGRDVRVTPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 PSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 YKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 EVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 TIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 ETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 DLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 VPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTAIEAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTAIEAPS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 STCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLGASDGVDNTVRPGDQGSSSQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 STCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLGASDGVDNTVRPGDQGSSSQPN
670 680 690 700 710 720
730 740
pF1KE9 SEERGENTSYRMEEKSDFMLEKLETKSV
::::::::::::::::::::::::::::
NP_060 SEERGENTSYRMEEKSDFMLEKLETKSV
730 740
>>XP_011509739 (OMIM: 612667) PREDICTED: Holliday juncti (636 aa)
initn: 4148 init1: 4148 opt: 4150 Z-score: 3668.6 bits: 689.3 E(85289): 1.3e-197
Smith-Waterman score: 4150; 99.4% identity (99.5% similar) in 619 aa overlap (130-748:19-636)
100 110 120 130 140 150
pF1KE9 GPELPSHRTVLGADSKSGEVDATSDQEESVAWALAPAVPQSPLKNELRRKYLTQVDILLQ
.: :::::::::::::::::::::::::
XP_011 MAPCKLQPGVLSFPRTAQSWE-PPAVPQSPLKNELRRKYLTQVDILLQ
10 20 30 40
160 170 180 190 200 210
pF1KE9 GAEYFECAGNRAGRDVRVTPLPSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAEYFECAGNRAGRDVRVTPLPSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLH
50 60 70 80 90 100
220 230 240 250 260 270
pF1KE9 PSSTDMALVPRNDSLSLQETSSSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSTDMALVPRNDSLSLQETSSSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKP
110 120 130 140 150 160
280 290 300 310 320 330
pF1KE9 SSIISTKTFIMQNWNSRRRHRYKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIISTKTFIMQNWNSRRRHRYKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRD
170 180 190 200 210 220
340 350 360 370 380 390
pF1KE9 CKNVLDVSCRKTGLKLEKAFLEVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKNVLDVSCRKTGLKLEKAFLEVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLD
230 240 250 260 270 280
400 410 420 430 440 450
pF1KE9 EENRFRTLKWLISPVKIVSRPTIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENRFRTLKWLISPVKIVSRPTIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLP
290 300 310 320 330 340
460 470 480 490 500 510
pF1KE9 DSWAMNMYRGGPASPGGLQGLETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSWAMNMYRGGPASPGGLQGLETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSD
350 360 370 380 390 400
520 530 540 550 560 570
pF1KE9 SSSSLPKTNPTHSATRPQQTSDLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSSLPKTNPTHSATRPQQTSDLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDE
410 420 430 440 450 460
580 590 600 610 620 630
pF1KE9 IKEEFDKLHQKYCLKSPGQMTVPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKEEFDKLHQKYCLKSPGQMTVPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKL
470 480 490 500 510 520
640 650 660 670 680 690
pF1KE9 PSSPLGCRKSLLGSTAIEAPSSTCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSPLGCRKSLLGSTAIEAPSSTCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLG
530 540 550 560 570 580
700 710 720 730 740
pF1KE9 ASDGVDNTVRPGDQGSSSQPNSEERGENTSYRMEEKSDFMLEKLETKSV
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASDGVDNTVRPGDQGSSSQPNSEERGENTSYRMEEKSDFMLEKLETKSV
590 600 610 620 630
>>NP_001269891 (OMIM: 612667) Holliday junction recognit (694 aa)
initn: 4149 init1: 4149 opt: 4149 Z-score: 3667.2 bits: 689.1 E(85289): 1.6e-197
Smith-Waterman score: 4559; 92.8% identity (92.8% similar) in 748 aa overlap (1-748:1-694)
10 20 30 40 50 60
pF1KE9 MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 QGLRIWGGRLIKERNEGEIQDSSMKPADRTDGSVQAAAWGPELPSHRTVLGADSKSGEVD
::::::::::::::::::::
NP_001 QGLRIWGGRLIKERNEGEIQ----------------------------------------
70 80
130 140 150 160 170 180
pF1KE9 ATSDQEESVAWALAPAVPQSPLKNELRRKYLTQVDILLQGAEYFECAGNRAGRDVRVTPL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------PAVPQSPLKNELRRKYLTQVDILLQGAEYFECAGNRAGRDVRVTPL
90 100 110 120
190 200 210 220 230 240
pF1KE9 PSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETS
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE9 SSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHR
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE9 YKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE9 EVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRP
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE9 TIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGL
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE9 ETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTS
430 440 450 460 470 480
550 560 570 580 590 600
pF1KE9 DLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMT
490 500 510 520 530 540
610 620 630 640 650 660
pF1KE9 VPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTAIEAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTAIEAPS
550 560 570 580 590 600
670 680 690 700 710 720
pF1KE9 STCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLGASDGVDNTVRPGDQGSSSQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLGASDGVDNTVRPGDQGSSSQPN
610 620 630 640 650 660
730 740
pF1KE9 SEERGENTSYRMEEKSDFMLEKLETKSV
::::::::::::::::::::::::::::
NP_001 SEERGENTSYRMEEKSDFMLEKLETKSV
670 680 690
>>NP_001269892 (OMIM: 612667) Holliday junction recognit (663 aa)
initn: 3948 init1: 3948 opt: 3948 Z-score: 3490.0 bits: 656.3 E(85289): 1.2e-187
Smith-Waterman score: 4295; 88.6% identity (88.6% similar) in 748 aa overlap (1-748:1-663)
10 20 30 40 50 60
pF1KE9 MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 QGLRIWGGRLIKERNEGEIQDSSMKPADRTDGSVQAAAWGPELPSHRTVLGADSKSGEVD
::::::::::::::::::::
NP_001 QGLRIWGGRLIKERNEGEIQ----------------------------------------
70 80
130 140 150 160 170 180
pF1KE9 ATSDQEESVAWALAPAVPQSPLKNELRRKYLTQVDILLQGAEYFECAGNRAGRDVRVTPL
:::::::::::::::
NP_001 ---------------------------------------------CAGNRAGRDVRVTPL
90
190 200 210 220 230 240
pF1KE9 PSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE9 SSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHR
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE9 YKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFL
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE9 EVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRP
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE9 TIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGL
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE9 ETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTS
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE9 DLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMT
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE9 VPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTAIEAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTAIEAPS
520 530 540 550 560 570
670 680 690 700 710 720
pF1KE9 STCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLGASDGVDNTVRPGDQGSSSQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLGASDGVDNTVRPGDQGSSSQPN
580 590 600 610 620 630
730 740
pF1KE9 SEERGENTSYRMEEKSDFMLEKLETKSV
::::::::::::::::::::::::::::
NP_001 SEERGENTSYRMEEKSDFMLEKLETKSV
640 650 660
748 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:05:09 2016 done: Sun Nov 6 12:05:11 2016
Total Scan time: 13.580 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]