Result of FASTA (omim) for
pFN21AE6786
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6786, 629 aa
1>>>pF1KE6786 629 - 629 aa - 629 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4617+/-0.00037; mu= 10.3572+/- 0.023
mean_var=132.8836+/-26.482, 0's: 0 Z-trim(117.0): 5 B-trim: 336 in 1/55
Lambda= 0.111260
statistics sampled from 28669 (28674) to 28669 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.336), width: 16
Scan time: 9.960
The best scores are: opt bits E(85289)
NP_001155048 (OMIM: 610747) protein Smaug homolog ( 630) 4204 686.4 7.9e-197
NP_056404 (OMIM: 610747) protein Smaug homolog 1 i ( 718) 2605 429.8 1.6e-119
NP_001155049 (OMIM: 610747) protein Smaug homolog ( 345) 1837 306.3 1.1e-82
>>NP_001155048 (OMIM: 610747) protein Smaug homolog 1 is (630 aa)
initn: 4204 init1: 4204 opt: 4204 Z-score: 3654.7 bits: 686.4 E(85289): 7.9e-197
Smith-Waterman score: 4204; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:2-630)
10 20 30 40 50
pF1KE6 MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLER
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLER
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 EANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 ESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESRQLLSYALIHPATSLEDRSALAMWLNHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 QNSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNSDDKLNGWQNSRDSGICINASNWQDKSMGCENGHVPLYSSSSVPTTINTIGTSTSTNV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 PAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLLK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 SLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQSP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 DCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 LVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGYR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE6 QQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNTT
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE6 ATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPVT
550 560 570 580 590 600
600 610 620
pF1KE6 EPDINNRLESLCLSMTEHALGDGVDRTSTI
::::::::::::::::::::::::::::::
NP_001 EPDINNRLESLCLSMTEHALGDGVDRTSTI
610 620 630
>>NP_056404 (OMIM: 610747) protein Smaug homolog 1 isofo (718 aa)
initn: 2602 init1: 2602 opt: 2605 Z-score: 2266.8 bits: 429.8 E(85289): 1.6e-119
Smith-Waterman score: 3629; 86.5% identity (86.7% similar) in 661 aa overlap (57-629:58-718)
30 40 50 60 70 80
pF1KE6 SLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKDKVISLLLTHL
::::::::::::::::::::::::::::::
NP_056 SLLKRVSQTQARFLQLCLEHSLADCAELHVLEREANSPGIINQWQQESKDKVISLLLTHL
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE6 PLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALIHPATSLEDRSALAMWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIEESRQLLSYALIHPATSLEDRSALAMWL
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE6 NHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQNSDDKLNGWQNSRDSGICINASNWQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NHLEDRTSTSFGGQNRGRSDSVDYGQTHYYHQRQNSDDKLNGWQNSRDSGICINASNWQD
150 160 170 180 190 200
210 220 230
pF1KE6 KSMGCENGHVPLYSSSSVPTTINTIGTSTST-----------------------------
:::::::::::::::::::::::::::::::
NP_056 KSMGCENGHVPLYSSSSVPTTINTIGTSTSTILSGQAHHSPLKRSVSLTPPMNVPNQPLG
210 220 230 240 250 260
pF1KE6 -----------------------------------------------------------N
.
NP_056 HGWMSHEDLRARGPQCLPSDHAPLSPQSSVASSGSGGSEHLEDQTTARNTFQEEGSGMKD
270 280 290 300 310 320
240 250 260 270 280 290
pF1KE6 VPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VPAWLKSLRLHKYAALFSQMTYEEMMALTECQLEAQNVTKGARHKIVISIQKLKERQNLL
330 340 350 360 370 380
300 310 320 330 340 350
pF1KE6 KSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPSLMGPESQS
390 400 410 420 430 440
360 370 380 390 400 410
pF1KE6 PDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTRVMGKVCTQ
450 460 470 480 490 500
420 430 440 450 460 470
pF1KE6 LLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRKTLLDISGY
510 520 530 540 550 560
480 490 500 510 520 530
pF1KE6 RQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGFVSSNQRNT
570 580 590 600 610 620
540 550 560 570 580 590
pF1KE6 TATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQQPEFQLPV
630 640 650 660 670 680
600 610 620
pF1KE6 TEPDINNRLESLCLSMTEHALGDGVDRTSTI
:::::::::::::::::::::::::::::::
NP_056 TEPDINNRLESLCLSMTEHALGDGVDRTSTI
690 700 710
>--
initn: 384 init1: 384 opt: 384 Z-score: 340.1 bits: 73.3 E(85289): 3.3e-12
Smith-Waterman score: 384; 100.0% identity (100.0% similar) in 56 aa overlap (1-56:2-57)
10 20 30 40 50
pF1KE6 MFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MMFRDQVGVLAGWFKGWNECEQTVALLSLLKRVSQTQARFLQLCLEHSLADCAELHVLER
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 EANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIE
NP_056 EANSPGIINQWQQESKDKVISLLLTHLPLLKPGNLDAKVEYMKLLPKILAHSIEHNQHIE
70 80 90 100 110 120
>>NP_001155049 (OMIM: 610747) protein Smaug homolog 1 is (345 aa)
initn: 1835 init1: 1835 opt: 1837 Z-score: 1605.3 bits: 306.3 E(85289): 1.1e-82
Smith-Waterman score: 1975; 89.4% identity (89.4% similar) in 341 aa overlap (321-625:1-341)
300 310 320 330 340 350
pF1KE6 LKERQNLLKSLERDIIEGGSLRIPLQELHQMILTPIKAYSSPSTTPEARRREPQAPRQPS
::::::::::::::::::::::::::::::
NP_001 MILTPIKAYSSPSTTPEARRREPQAPRQPS
10 20 30
360 370 380 390 400 410
pF1KE6 LMGPESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMGPESQSPDCKDGAAATGATATPSAGASGGLQPHQLSSCDGELAVAPLPEGDLPGQFTR
40 50 60 70 80 90
420 430 440 450 460 470
pF1KE6 VMGKVCTQLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMGKVCTQLLVSRPDEENISSYLQLIDKCLIHEAFTETQKKRLLSWKQQVQKLFRSFPRK
100 110 120 130 140 150
480 490 500 510 520 530
pF1KE6 TLLDISGYRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLDISGYRQQRNRGFGQSNSLPTAGSVGGGMGRRNPRQYQIPSRNVPSARLGLLGTSGF
160 170 180 190 200 210
540 550 560 570 580 590
pF1KE6 VSSNQRNTTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSNQRNTTATPTIMKQGRQNLWFANPGGSNSMPSRTHSSVQRTRSLPVHTSPQNMLMFQ
220 230 240 250 260 270
600 610
pF1KE6 QP------------------------------------EFQLPVTEPDINNRLESLCLSM
:: ::::::::::::::::::::::
NP_001 QPGSQVHSGLCLTDLRGWLSLSGAPSMPALTVPKSSQGEFQLPVTEPDINNRLESLCLSM
280 290 300 310 320 330
620
pF1KE6 TEHALGDGVDRTSTI
:::::::::::
NP_001 TEHALGDGVDRTSTI
340
629 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:20:35 2016 done: Tue Nov 8 16:20:36 2016
Total Scan time: 9.960 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]