Result of FASTA (ccds) for
pFN21AE6758
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6758, 583 aa
1>>>pF1KE6758 583 - 583 aa - 583 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5263+/-0.000756; mu= 13.8596+/- 0.045
mean_var=100.1070+/-19.927, 0's: 0 Z-trim(111.2): 16 B-trim: 514 in 2/52
Lambda= 0.128186
statistics sampled from 12221 (12230) to 12221 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.376), width: 16
Scan time: 3.270
The best scores are: opt bits E(32554)
CCDS54141.1 EME1 gene_id:146956|Hs108|chr17 ( 583) 3867 725.5 4.4e-209
CCDS11565.1 EME1 gene_id:146956|Hs108|chr17 ( 570) 2476 468.3 1.2e-131
CCDS58404.1 EME2 gene_id:197342|Hs108|chr16 ( 379) 508 104.2 3.1e-22
>>CCDS54141.1 EME1 gene_id:146956|Hs108|chr17 (583 aa)
initn: 3867 init1: 3867 opt: 3867 Z-score: 3867.2 bits: 725.5 E(32554): 4.4e-209
Smith-Waterman score: 3867; 99.8% identity (100.0% similar) in 583 aa overlap (1-583:1-583)
10 20 30 40 50 60
pF1KE6 MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELFSPPVPDIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVK
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ELFSPPVPEIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SVLDHQNNEGASCDWKKPFPKIPEVPLHDTPERSAADNKDLILDPCCQLPAYLSTCPGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVLDHQNNEGASCDWKKPFPKIPEVPLHDTPERSAADNKDLILDPCCQLPAYLSTCPGQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVTRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVTRM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRRRAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRRRAGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 EDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVIVDQEKCFSLELLFFDFLPCTSAQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LVIVDQEKCFSLELLFFDFLPCTSAQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 AEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 AEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 GVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLL
490 500 510 520 530 540
550 560 570 580
pF1KE6 ADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD
:::::::::::::::::::::::::::::::::::::::::::
CCDS54 ADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD
550 560 570 580
>>CCDS11565.1 EME1 gene_id:146956|Hs108|chr17 (570 aa)
initn: 2476 init1: 2476 opt: 2476 Z-score: 2477.1 bits: 468.3 E(32554): 1.2e-131
Smith-Waterman score: 3740; 97.6% identity (97.8% similar) in 583 aa overlap (1-583:1-570)
10 20 30 40 50 60
pF1KE6 MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELFSPPVPDIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVK
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ELFSPPVPEIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SVLDHQNNEGASCDWKKPFPKIPEVPLHDTPERSAADNKDLILDPCCQLPAYLSTCPGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SVLDHQNNEGASCDWKKPFPKIPEVPLHDTPERSAADNKDLILDPCCQLPAYLSTCPGQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVTRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVTRM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRRRAGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRRRAGPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 EDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVIVDQEKCFSLELLFFDFLPCTSAQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVD
::::::::::: ::::::::::::::::::::::::::::::::::::
CCDS11 LVIVDQEKCFS-------------AQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVD
370 380 390 400
430 440 450 460 470 480
pF1KE6 AEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAG
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE6 GVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLL
470 480 490 500 510 520
550 560 570 580
pF1KE6 ADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD
:::::::::::::::::::::::::::::::::::::::::::
CCDS11 ADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD
530 540 550 560 570
>>CCDS58404.1 EME2 gene_id:197342|Hs108|chr16 (379 aa)
initn: 598 init1: 413 opt: 508 Z-score: 512.8 bits: 104.2 E(32554): 3.1e-22
Smith-Waterman score: 606; 35.3% identity (59.1% similar) in 394 aa overlap (194-580:28-376)
170 180 190 200 210 220
pF1KE6 DPCCQLPAYLSTCPGQSSSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKE
:: . . :. .. :: . :: ..
CCDS58 MARVGPGRAGVSCQGRGRGRGGSGQRRPPTWEISDSDAEDSAGS-----EAAARARD
10 20 30 40 50
230 240 250 260 270 280
pF1KE6 STLRRQERKNAALVTRMKAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIE
. ::. :: . :. :::. ::.. : .: ..:. :. :. ::... :.: ::
CCDS58 PA---GERRAAAEALRL--LRPEQVLKRLAVCVDTAILEDAGADVLMEALEALGCECRIE
60 70 80 90 100
290 300 310 320 330
pF1KE6 AQAVPCSVTWRRRAGP-----SEDREDWVE-EPTVLVLLRAEAFVSMIDNGKQGSLDSTM
: :. : : :.: : : :. : .:.::. : :.. . . : .
CCDS58 PQRPARSLRWTR-ASPDPCPRSLPPEVWAAGEQELLLLLEPEEFLQGVATLTQ------I
110 120 130 140 150 160
340 350 360 370 380 390
pF1KE6 KGKETLQGFVTDITAKTAGKALSLVIVDQEKCFSLELLFFDFLPCTSAQNPPRRGKQGAN
.: ... : :: :... .: .: ..: ..
CCDS58 SGPTHWVPWISPET--TARPHLAVIGLDA------------YL----------WSRQHVS
170 180 190
400 410 420 430 440 450
pF1KE6 KQTKKQQQRQPE-ASIGSMVSRVDAEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAV
. : :: ..:. :. :: ..::::: ::: .. .. .: ::.::. .:: :::.
CCDS58 RGT--QQPESPKVAGAEVAVSWPEVEEALVLLQLWANLDVLLVASWQELSRHVCAVTKAL
200 210 220 230 240 250
460 470 480 490 500 510
pF1KE6 AEAPFKKLRDETTFSFCLESDWAGGVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNA
:. :.:. :. .:::: . ::.: : : :: .:::::.:..::: .:.:::.:
CCDS58 AQYPLKQYRESQAFSFCTAGRWAAGEPVARDGAGLQAAWRRQIRQFSRVSPAVADAVVTA
260 270 280 290 300 310
520 530 540 550 560 570
pF1KE6 YPSPQLLVQAYQQCFSDKERQNLLADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPH
.:::.:: :: . : ...::..::::. : .:: . ::.::.::::: : .:: .:
CCDS58 FPSPRLLQQALEACSTERERMGLLADLPVPPSEG--GRPRRVGPDLSRRICLFLTTANPD
320 330 340 350 360 370
580
pF1KE6 LSLDSAD
: ::
CCDS58 LLLDLGS
583 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:05:51 2016 done: Tue Nov 8 16:05:52 2016
Total Scan time: 3.270 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]