Result of FASTA (omim) for
pFN21AE6753
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6753, 669 aa
1>>>pF1KE6753 669 - 669 aa - 669 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5409+/-0.000423; mu= 17.7701+/- 0.026
mean_var=68.4640+/-13.156, 0's: 0 Z-trim(111.5): 126 B-trim: 0 in 0/50
Lambda= 0.155004
statistics sampled from 20012 (20139) to 20012 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.236), width: 16
Scan time: 10.320
The best scores are: opt bits E(85289)
XP_011531462 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 4578 1033.4 0
XP_011531461 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 4578 1033.4 0
XP_011531463 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 4578 1033.4 0
NP_653176 (OMIM: 610228) calpain-13 [Homo sapiens] ( 669) 4578 1033.4 0
XP_016860754 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 4578 1033.4 0
XP_016860753 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 4578 1033.4 0
XP_016860755 (OMIM: 610228) PREDICTED: calpain-13 ( 665) 4535 1023.8 0
XP_011531465 (OMIM: 610228) PREDICTED: calpain-13 ( 433) 2876 652.7 8.1e-187
XP_011531165 (OMIM: 610229) PREDICTED: calpain-14 ( 684) 1179 273.3 2.1e-72
NP_001138594 (OMIM: 610229) calpain-14 isoform 1 [ ( 684) 1179 273.3 2.1e-72
XP_011531167 (OMIM: 610229) PREDICTED: calpain-14 ( 684) 1179 273.3 2.1e-72
XP_011531166 (OMIM: 610229) PREDICTED: calpain-14 ( 684) 1179 273.3 2.1e-72
XP_006715050 (OMIM: 604822) PREDICTED: calpain-11 ( 650) 964 225.2 5.9e-58
XP_006715048 (OMIM: 604822) PREDICTED: calpain-11 ( 724) 964 225.2 6.5e-58
NP_008989 (OMIM: 604822) calpain-11 [Homo sapiens] ( 739) 964 225.2 6.6e-58
XP_006715047 (OMIM: 604822) PREDICTED: calpain-11 ( 740) 964 225.2 6.6e-58
XP_011512577 (OMIM: 604822) PREDICTED: calpain-11 ( 743) 964 225.2 6.6e-58
XP_011512576 (OMIM: 604822) PREDICTED: calpain-11 ( 744) 964 225.2 6.6e-58
XP_011543594 (OMIM: 114220,616907) PREDICTED: calp ( 714) 937 219.2 4.2e-56
NP_001185798 (OMIM: 114220,616907) calpain-1 catal ( 714) 937 219.2 4.2e-56
NP_005177 (OMIM: 114220,616907) calpain-1 catalyti ( 714) 937 219.2 4.2e-56
XP_006718761 (OMIM: 114220,616907) PREDICTED: calp ( 714) 937 219.2 4.2e-56
NP_001185797 (OMIM: 114220,616907) calpain-1 catal ( 714) 937 219.2 4.2e-56
NP_006606 (OMIM: 606401) calpain-9 isoform 1 [Homo ( 690) 928 217.2 1.6e-55
XP_011542319 (OMIM: 606401) PREDICTED: calpain-9 i ( 721) 928 217.2 1.7e-55
XP_011542588 (OMIM: 114230) PREDICTED: calpain-2 c ( 447) 917 214.6 6.2e-55
NP_001739 (OMIM: 114230) calpain-2 catalytic subun ( 700) 917 214.7 9.2e-55
XP_016881854 (OMIM: 608839) PREDICTED: calpain-12 ( 503) 839 197.2 1.2e-49
XP_016881852 (OMIM: 608839) PREDICTED: calpain-12 ( 565) 839 197.2 1.4e-49
XP_016881851 (OMIM: 608839) PREDICTED: calpain-12 ( 590) 839 197.2 1.4e-49
XP_016881850 (OMIM: 608839) PREDICTED: calpain-12 ( 604) 839 197.3 1.4e-49
XP_016881849 (OMIM: 608839) PREDICTED: calpain-12 ( 652) 839 197.3 1.5e-49
XP_016881848 (OMIM: 608839) PREDICTED: calpain-12 ( 676) 839 197.3 1.6e-49
XP_016881847 (OMIM: 608839) PREDICTED: calpain-12 ( 698) 839 197.3 1.6e-49
XP_016881846 (OMIM: 608839) PREDICTED: calpain-12 ( 699) 839 197.3 1.6e-49
XP_016881845 (OMIM: 608839) PREDICTED: calpain-12 ( 702) 839 197.3 1.6e-49
NP_653292 (OMIM: 608839) calpain-12 [Homo sapiens] ( 719) 839 197.3 1.7e-49
XP_016881844 (OMIM: 608839) PREDICTED: calpain-12 ( 723) 839 197.3 1.7e-49
NP_775110 (OMIM: 114240,253600) calpain-3 isoform ( 729) 835 196.4 3.1e-49
NP_001139540 (OMIM: 114230) calpain-2 catalytic su ( 622) 779 183.8 1.6e-45
NP_057536 (OMIM: 606401) calpain-9 isoform 2 [Homo ( 664) 709 168.2 8.8e-41
XP_011542320 (OMIM: 606401) PREDICTED: calpain-9 i ( 695) 709 168.2 9.2e-41
NP_001306605 (OMIM: 606401) calpain-9 isoform 3 [H ( 627) 647 154.3 1.3e-36
XP_011542321 (OMIM: 606401) PREDICTED: calpain-9 i ( 658) 647 154.3 1.3e-36
NP_077320 (OMIM: 114240,253600) calpain-3 isoform ( 815) 576 138.5 9.4e-32
NP_000061 (OMIM: 114240,253600) calpain-3 isoform ( 821) 576 138.5 9.5e-32
XP_016855587 (OMIM: 606401) PREDICTED: calpain-9 i ( 693) 567 136.5 3.3e-31
NP_075573 (OMIM: 601283,605286) calpain-10 isoform ( 517) 524 126.8 2e-28
NP_075571 (OMIM: 601283,605286) calpain-10 isoform ( 672) 524 126.8 2.5e-28
NP_004046 (OMIM: 193235,602537) calpain-5 [Homo sa ( 640) 520 125.9 4.5e-28
>>XP_011531462 (OMIM: 610228) PREDICTED: calpain-13 isof (669 aa)
initn: 4578 init1: 4578 opt: 4578 Z-score: 5529.0 bits: 1033.4 E(85289): 0
Smith-Waterman score: 4578; 99.9% identity (100.0% similar) in 669 aa overlap (1-669:1-669)
10 20 30 40 50 60
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDGSQEWEETCDPR
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
610 620 630 640 650 660
pF1KE6 EWMSLVMYN
:::::::::
XP_011 EWMSLVMYN
>>XP_011531461 (OMIM: 610228) PREDICTED: calpain-13 isof (669 aa)
initn: 4578 init1: 4578 opt: 4578 Z-score: 5529.0 bits: 1033.4 E(85289): 0
Smith-Waterman score: 4578; 99.9% identity (100.0% similar) in 669 aa overlap (1-669:1-669)
10 20 30 40 50 60
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDGSQEWEETCDPR
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
610 620 630 640 650 660
pF1KE6 EWMSLVMYN
:::::::::
XP_011 EWMSLVMYN
>>XP_011531463 (OMIM: 610228) PREDICTED: calpain-13 isof (669 aa)
initn: 4578 init1: 4578 opt: 4578 Z-score: 5529.0 bits: 1033.4 E(85289): 0
Smith-Waterman score: 4578; 99.9% identity (100.0% similar) in 669 aa overlap (1-669:1-669)
10 20 30 40 50 60
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDGSQEWEETCDPR
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
610 620 630 640 650 660
pF1KE6 EWMSLVMYN
:::::::::
XP_011 EWMSLVMYN
>>NP_653176 (OMIM: 610228) calpain-13 [Homo sapiens] (669 aa)
initn: 4578 init1: 4578 opt: 4578 Z-score: 5529.0 bits: 1033.4 E(85289): 0
Smith-Waterman score: 4578; 99.9% identity (100.0% similar) in 669 aa overlap (1-669:1-669)
10 20 30 40 50 60
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDGSQEWEETCDPR
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_653 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
610 620 630 640 650 660
pF1KE6 EWMSLVMYN
:::::::::
NP_653 EWMSLVMYN
>>XP_016860754 (OMIM: 610228) PREDICTED: calpain-13 isof (669 aa)
initn: 4578 init1: 4578 opt: 4578 Z-score: 5529.0 bits: 1033.4 E(85289): 0
Smith-Waterman score: 4578; 99.9% identity (100.0% similar) in 669 aa overlap (1-669:1-669)
10 20 30 40 50 60
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDGSQEWEETCDPR
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
610 620 630 640 650 660
pF1KE6 EWMSLVMYN
:::::::::
XP_016 EWMSLVMYN
>>XP_016860753 (OMIM: 610228) PREDICTED: calpain-13 isof (669 aa)
initn: 4578 init1: 4578 opt: 4578 Z-score: 5529.0 bits: 1033.4 E(85289): 0
Smith-Waterman score: 4578; 99.9% identity (100.0% similar) in 669 aa overlap (1-669:1-669)
10 20 30 40 50 60
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDGSQEWEETCDPR
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
610 620 630 640 650 660
pF1KE6 EWMSLVMYN
:::::::::
XP_016 EWMSLVMYN
>>XP_016860755 (OMIM: 610228) PREDICTED: calpain-13 isof (665 aa)
initn: 2891 init1: 2891 opt: 4535 Z-score: 5477.1 bits: 1023.8 E(85289): 0
Smith-Waterman score: 4535; 99.3% identity (99.4% similar) in 669 aa overlap (1-669:1-665)
10 20 30 40 50 60
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDGSQEWEETCDPR
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVIL----RFRE
370 380 390 400 410
430 440 450 460 470 480
pF1KE6 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE6 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE6 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTD
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE6 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEM
600 610 620 630 640 650
pF1KE6 EWMSLVMYN
:::::::::
XP_016 EWMSLVMYN
660
>>XP_011531465 (OMIM: 610228) PREDICTED: calpain-13 isof (433 aa)
initn: 2909 init1: 2876 opt: 2876 Z-score: 3474.9 bits: 652.7 E(85289): 8.1e-187
Smith-Waterman score: 2876; 99.8% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDGSQEWEETCDPR
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 MENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILHPIDVVSC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDS
XP_011 PSKKHLSAHPSLR
430
>>XP_011531165 (OMIM: 610229) PREDICTED: calpain-14 isof (684 aa)
initn: 1064 init1: 456 opt: 1179 Z-score: 1421.0 bits: 273.3 E(85289): 2.1e-72
Smith-Waterman score: 1319; 36.1% identity (64.0% similar) in 675 aa overlap (19-669:28-684)
10 20 30 40 50
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKL
::: .: .:: : :.: .:::. ::::.
XP_011 MSLWPPFRCRWKLAPRYSRRASPQQPQQDFEALLAECLRNGCLFEDTSFPATLSSIGSGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 LQEKRLSNVIWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQK
: .: . :::: .: ..: .: . .:.:. :: ..:::::::: .:. . . ..
XP_011 LLQKLPPRLQWKRPPELHSNP-QFYFAKAKRLDLCQGIVGDCWFLAALQALALHQDILSR
70 80 90 100 110
120 130 140 150 160
pF1KE6 IL-MVQSFSHQYAGIFRFRFWQCGQWVEVVIDDRLPV-QGDKCLFVRPRHQNQEFWPCLL
.. . :::...::::::: ::. :.:: ::::::::: .. . .:: ..: :: ::
XP_011 VVPLNQSFTEKYAGIFRFWFWHYGNWVPVVIDDRLPVNEAGQLVFVSSTYKNL-FWGALL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 EKAYAKLLGSYSDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCA
::::::: ::: ::. : . .::::.:::: .:.: . .: . :: .:: :
XP_011 EKAYAKLSGSYEDLQSGQVSEALVDFTGGVTMTINLAEAHGNLWDILIEATYNRTLIGCQ
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 TPSGPTDTAQAMENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDG
: :: . .::::: ::::.:: ... .. : ...: :::: ..::.: :::.
XP_011 THSGE----KILENGLVEGHAYTLTGIRKVTCKHRPEYLVKLRNPWG--KVEWKGDWSDS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 SQEWEETCDPRKSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQ
:..:: .: : .: .::::::. :::. .:. . ::. : :.. . . :.
XP_011 SSKWELLSPKEKILLLRKDNDGEFWMTLQDFKTHFVLLVICKLTPGLLSQEAA--QKWTY
300 310 320 330 340 350
350 360 370 380 390
pF1KE6 IMFRKQVILGNTAGGPRN--------DAQFNFSVQEPMEGTNVV----VCVTVAVTPSNL
: . . .:::: :. . :: .:: .: :: . : :.. : .
XP_011 TMREGRWEKRSTAGGQRQLLQDTFWKNPQFLLSVWRPEEGRRSLRPCSVLVSLLQKPRH-
360 370 380 390 400
400 410 420 430 440 450
pF1KE6 KAEDAKFPLDFQVILAGSQRFRE---KFPPVFFSSFRNTVQSSNNKF--RRNFTMTYHLS
. . : : . : ..... ..:: ::. ::: :. ..: ... .. :
XP_011 RCRKRKPLLAIGFYLYRMNKYHDDQRRLPPEFFQ--RNTPLSQPDRFLKEKEVSQELCLE
410 420 430 440 450 460
460 470 480 490 500
pF1KE6 PGNYVVVA---QTRRKSAEFLLRIFLKMPDSDRHLSSHFNLRMKGSPSEHGSQQSIFNRY
::.:..: ....:: ::.::.: . . :. . : ... :. .:...
XP_011 PGTYLIVPCILEAHQKS-EFVLRVFSRKHIFYEIGSNSGVVFSKEIEDQNERQDEFFTKF
470 480 490 500 510 520
510 520 530 540 550 560
pF1KE6 AQQRLDIDATQLQGLLNQELLT--GPPGDMFSLDECRSLVALMELKVNGRLDQEEFARLW
... .:.:.:::.:::: . : .:::. :....::..:...: .. .:: ::
XP_011 FEKHPEINAVQLQNLLNQMTWSSLGSRQPFFSLEACQGILALLDLNASGTMSIQEFRDLW
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE6 KRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTDFLRGIFISRELLHLVTLRYSDSVGRVS
:.: :.::.: . . : : :. .. . ::..: .. .:. .::. ...
XP_011 KQLKLSQKVFHKQDRGSGYLN----WEQLHAAMREAGIMLSDDVCQLMLIRYGGPRLQMD
590 600 610 620 630 640
630 640 650 660
pF1KE6 FPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEMEWMSLVMYN
: :.. ...:.: : .:.::..::::.:: . ::: ...:.
XP_011 FVSFIHLMLRVENMEDVFQNLTQDGKGIYLQKPEWMMMALYS
650 660 670 680
>>NP_001138594 (OMIM: 610229) calpain-14 isoform 1 [Homo (684 aa)
initn: 1064 init1: 456 opt: 1179 Z-score: 1421.0 bits: 273.3 E(85289): 2.1e-72
Smith-Waterman score: 1319; 36.1% identity (64.0% similar) in 675 aa overlap (19-669:28-684)
10 20 30 40 50
pF1KE6 MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKL
::: .: .:: : :.: .:::. ::::.
NP_001 MSLWPPFRCRWKLAPRYSRRASPQQPQQDFEALLAECLRNGCLFEDTSFPATLSSIGSGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 LQEKRLSNVIWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQK
: .: . :::: .: ..: .: . .:.:. :: ..:::::::: .:. . . ..
NP_001 LLQKLPPRLQWKRPPELHSNP-QFYFAKAKRLDLCQGIVGDCWFLAALQALALHQDILSR
70 80 90 100 110
120 130 140 150 160
pF1KE6 IL-MVQSFSHQYAGIFRFRFWQCGQWVEVVIDDRLPV-QGDKCLFVRPRHQNQEFWPCLL
.. . :::...::::::: ::. :.:: ::::::::: .. . .:: ..: :: ::
NP_001 VVPLNQSFTEKYAGIFRFWFWHYGNWVPVVIDDRLPVNEAGQLVFVSSTYKNL-FWGALL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 EKAYAKLLGSYSDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCA
::::::: ::: ::. : . .::::.:::: .:.: . .: . :: .:: :
NP_001 EKAYAKLSGSYEDLQSGQVSEALVDFTGGVTMTINLAEAHGNLWDILIEATYNRTLIGCQ
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 TPSGPTDTAQAMENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSDG
: :: . .::::: ::::.:: ... .. : ...: :::: ..::.: :::.
NP_001 THSGE----KILENGLVEGHAYTLTGIRKVTCKHRPEYLVKLRNPWG--KVEWKGDWSDS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 SQEWEETCDPRKSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQ
:..:: .: : .: .::::::. :::. .:. . ::. : :.. . . :.
NP_001 SSKWELLSPKEKILLLRKDNDGEFWMTLQDFKTHFVLLVICKLTPGLLSQEAA--QKWTY
300 310 320 330 340 350
350 360 370 380 390
pF1KE6 IMFRKQVILGNTAGGPRN--------DAQFNFSVQEPMEGTNVV----VCVTVAVTPSNL
: . . .:::: :. . :: .:: .: :: . : :.. : .
NP_001 TMREGRWEKRSTAGGQRQLLQDTFWKNPQFLLSVWRPEEGRRSLRPCSVLVSLLQKPRH-
360 370 380 390 400
400 410 420 430 440 450
pF1KE6 KAEDAKFPLDFQVILAGSQRFRE---KFPPVFFSSFRNTVQSSNNKF--RRNFTMTYHLS
. . : : . : ..... ..:: ::. ::: :. ..: ... .. :
NP_001 RCRKRKPLLAIGFYLYRMNKYHDDQRRLPPEFFQ--RNTPLSQPDRFLKEKEVSQELCLE
410 420 430 440 450 460
460 470 480 490 500
pF1KE6 PGNYVVVA---QTRRKSAEFLLRIFLKMPDSDRHLSSHFNLRMKGSPSEHGSQQSIFNRY
::.:..: ....:: ::.::.: . . :. . : ... :. .:...
NP_001 PGTYLIVPCILEAHQKS-EFVLRVFSRKHIFYEIGSNSGVVFSKEIEDQNERQDEFFTKF
470 480 490 500 510 520
510 520 530 540 550 560
pF1KE6 AQQRLDIDATQLQGLLNQELLT--GPPGDMFSLDECRSLVALMELKVNGRLDQEEFARLW
... .:.:.:::.:::: . : .:::. :....::..:...: .. .:: ::
NP_001 FEKHPEINAVQLQNLLNQMTWSSLGSRQPFFSLEACQGILALLDLNASGTMSIQEFRDLW
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE6 KRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTDFLRGIFISRELLHLVTLRYSDSVGRVS
:.: :.::.: . . : : :. .. . ::..: .. .:. .::. ...
NP_001 KQLKLSQKVFHKQDRGSGYLN----WEQLHAAMREAGIMLSDDVCQLMLIRYGGPRLQMD
590 600 610 620 630 640
630 640 650 660
pF1KE6 FPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEMEWMSLVMYN
: :.. ...:.: : .:.::..::::.:: . ::: ...:.
NP_001 FVSFIHLMLRVENMEDVFQNLTQDGKGIYLQKPEWMMMALYS
650 660 670 680
669 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:02:34 2016 done: Tue Nov 8 16:02:35 2016
Total Scan time: 10.320 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]