FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6662, 276 aa
  1>>>pF1KE6662 276 - 276 aa - 276 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9851+/-0.000361; mu= 16.6535+/- 0.022
 mean_var=61.5850+/-12.248, 0's: 0 Z-trim(112.6): 20  B-trim: 0 in 0/55
 Lambda= 0.163432
 statistics sampled from 21625 (21636) to 21625 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.254), width:  16
 Scan time:  6.460

The best scores are:                                      opt bits E(85289)
NP_689945 (OMIM: 612648,612650) radial spoke head  ( 276) 1809 435.0 7.2e-122
XP_005248958 (OMIM: 612648,612650) PREDICTED: radi ( 321) 1460 352.8 4.8e-97
XP_016865915 (OMIM: 612648,612650) PREDICTED: radi ( 179) 1136 276.2   3e-74
NP_001180270 (OMIM: 612648,612650) radial spoke he ( 306)  854 209.9 4.8e-54
XP_006715077 (OMIM: 612648,612650) PREDICTED: radi ( 140)  480 121.5 8.8e-28


>>NP_689945 (OMIM: 612648,612650) radial spoke head prot  (276 aa)
 initn: 1809 init1: 1809 opt: 1809  Z-score: 2308.9  bits: 435.0 E(85289): 7.2e-122
Smith-Waterman score: 1809; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:1-276)

               10        20        30        40        50        60
pF1KE6 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 EGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 EGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 AKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQMERGNALVVLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 AKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQMERGNALVVLR
              190       200       210       220       230       240

              250       260       270      
pF1KE6 SLLWPGLTFYHAPRTKNYGYVYVGTGEKNMDLPFML
       ::::::::::::::::::::::::::::::::::::
NP_689 SLLWPGLTFYHAPRTKNYGYVYVGTGEKNMDLPFML
              250       260       270      

>>XP_005248958 (OMIM: 612648,612650) PREDICTED: radial s  (321 aa)
 initn: 1460 init1: 1460 opt: 1460  Z-score: 1863.3  bits: 352.8 E(85289): 4.8e-97
Smith-Waterman score: 1460; 93.1% identity (95.9% similar) in 245 aa overlap (1-245:1-245)

               10        20        30        40        50        60
pF1KE6 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 EGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 AKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQMERGNALVVLR
       ::::::::::::::::::::::::::::::::::::::::::::: .. .   . :.   
XP_005 AKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSEAVVQGDFTWLLSRC
              190       200       210       220       230       240

              250       260       270                              
pF1KE6 SLLWPGLTFYHAPRTKNYGYVYVGTGEKNMDLPFML                        
       .. ::                                                       
XP_005 GFGWPCSWDSCSVSMRVLEHPDGEGQCPGGAAQPALAGPHLLPCSPHQELWLRLRGHWRE
              250       260       270       280       290       300

>>XP_016865915 (OMIM: 612648,612650) PREDICTED: radial s  (179 aa)
 initn: 1136 init1: 1136 opt: 1136  Z-score: 1454.1  bits: 276.2 E(85289): 3e-74
Smith-Waterman score: 1136; 98.9% identity (98.9% similar) in 179 aa overlap (1-179:1-179)

               10        20        30        40        50        60
pF1KE6 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 EGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSE
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::  :: 
XP_016 EGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGSLLS 
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KE6 AKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQMERGNALVVLR

>>NP_001180270 (OMIM: 612648,612650) radial spoke head p  (306 aa)
 initn: 854 init1: 854 opt: 854  Z-score: 1091.3  bits: 209.9 E(85289): 4.8e-54
Smith-Waterman score: 1333; 86.9% identity (89.8% similar) in 245 aa overlap (1-245:1-230)

               10        20        30        40        50        60
pF1KE6 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 EGEKVFEEEIVVQIKEETRLVSVIDQIDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSE
       :::::::::::               ::::::::::::::::::::::::::::::::::
NP_001 EGEKVFEEEIV---------------IDKAVAIIPRGALFKTPFGPTHVNRTFEGLSLSE
              130                      140       150       160     

              190       200       210       220       230       240
pF1KE6 AKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSWSIQMERGNALVVLR
       ::::::::::::::::::::::::::::::::::::::::::::: .. .   . :.   
NP_001 AKKLSSYFHFREPVELKNKTLLEKADLDPSLDFMDSLEHDIPKGSEAVVQGDFTWLLSRC
         170       180       190       200       210       220     

              250       260       270                              
pF1KE6 SLLWPGLTFYHAPRTKNYGYVYVGTGEKNMDLPFML                        
       .. ::                                                       
NP_001 GFGWPCSWDSCSVSMRVLEHPDGEGQCPGGAAQPALAGPHLLPCSPHQELWLRLRGHWRE
         230       240       250       260       270       280     

>>XP_006715077 (OMIM: 612648,612650) PREDICTED: radial s  (140 aa)
 initn: 496 init1: 480 opt: 480  Z-score: 619.7  bits: 121.5 E(85289): 8.8e-28
Smith-Waterman score: 480; 100.0% identity (100.0% similar) in 75 aa overlap (1-75:1-75)

               10        20        30        40        50        60
pF1KE6 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDADSLLLSLELASGSGQGLSPDRRASLLTSLMLVKRDYRYDRVLFWGRILGLVADYYIA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QGLSEDQLAPRKTLYSLNCTEWSLLPPATEEMVAQSSVVKGRFMGDPSYEYEHTELQKVN
       :::::::::::::::                                             
XP_006 QGLSEDQLAPRKTLYRSRSRKRPAWCLSLTRLTRLWPSSPEAPSSRPLLDPPMSIGPLKD
               70        80        90       100       110       120




276 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 15:12:49 2016 done: Tue Nov  8 15:12:50 2016
 Total Scan time:  6.460 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]