Result of FASTA (ccds) for
pFN21AE6650
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6650, 234 aa
1>>>pF1KE6650 234 - 234 aa - 234 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6668+/-0.000847; mu= 11.8201+/- 0.051
mean_var=60.5410+/-12.406, 0's: 0 Z-trim(105.8): 25 B-trim: 454 in 1/50
Lambda= 0.164835
statistics sampled from 8577 (8600) to 8577 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.264), width: 16
Scan time: 1.280
The best scores are: opt bits E(32554)
CCDS41999.1 INF2 gene_id:64423|Hs108|chr14 ( 234) 1503 365.8 1.4e-101
CCDS45173.1 INF2 gene_id:64423|Hs108|chr14 (1240) 1503 365.9 6.7e-101
CCDS9989.2 INF2 gene_id:64423|Hs108|chr14 (1249) 1503 365.9 6.7e-101
CCDS46429.1 FMNL2 gene_id:114793|Hs108|chr2 (1092) 293 78.2 2.5e-14
CCDS58323.1 DAAM1 gene_id:23002|Hs108|chr14 (1068) 292 77.9 2.9e-14
CCDS9737.1 DAAM1 gene_id:23002|Hs108|chr14 (1078) 292 77.9 2.9e-14
CCDS41780.1 FMNL3 gene_id:91010|Hs108|chr12 ( 976) 291 77.7 3.1e-14
CCDS44874.1 FMNL3 gene_id:91010|Hs108|chr12 (1027) 285 76.2 8.7e-14
CCDS11497.1 FMNL1 gene_id:752|Hs108|chr17 (1100) 285 76.3 9.3e-14
CCDS54999.1 DAAM2 gene_id:23500|Hs108|chr6 (1067) 282 75.5 1.5e-13
CCDS56426.1 DAAM2 gene_id:23500|Hs108|chr6 (1068) 282 75.5 1.5e-13
CCDS58297.1 DIAPH3 gene_id:81624|Hs108|chr13 (1112) 251 68.2 2.6e-11
CCDS58294.1 DIAPH3 gene_id:81624|Hs108|chr13 (1123) 251 68.2 2.6e-11
CCDS58295.1 DIAPH3 gene_id:81624|Hs108|chr13 (1147) 251 68.2 2.6e-11
CCDS58296.1 DIAPH3 gene_id:81624|Hs108|chr13 (1182) 251 68.2 2.7e-11
CCDS41898.1 DIAPH3 gene_id:81624|Hs108|chr13 (1193) 251 68.2 2.7e-11
>>CCDS41999.1 INF2 gene_id:64423|Hs108|chr14 (234 aa)
initn: 1503 init1: 1503 opt: 1503 Z-score: 1937.1 bits: 365.8 E(32554): 1.4e-101
Smith-Waterman score: 1503; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234)
10 20 30 40 50 60
pF1KE6 MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 NQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSI
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 VMNELSGSDNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 VMNELSGSDNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLR
190 200 210 220 230
>>CCDS45173.1 INF2 gene_id:64423|Hs108|chr14 (1240 aa)
initn: 1503 init1: 1503 opt: 1503 Z-score: 1925.0 bits: 365.9 E(32554): 6.7e-101
Smith-Waterman score: 1503; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234)
10 20 30 40 50 60
pF1KE6 MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 NQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSI
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 VMNELSGSDNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VMNELSGSDNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLRDLEDAD
190 200 210 220 230 240
CCDS45 LLIQLEAFEEAKAEDEEELLRVSGGVDMSSHQEVFASLFHKVSCSPVSAQLLSVLQGLLH
250 260 270 280 290 300
>>CCDS9989.2 INF2 gene_id:64423|Hs108|chr14 (1249 aa)
initn: 1503 init1: 1503 opt: 1503 Z-score: 1924.9 bits: 365.9 E(32554): 6.7e-101
Smith-Waterman score: 1503; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234)
10 20 30 40 50 60
pF1KE6 MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 DGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 NQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSI
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 VMNELSGSDNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 VMNELSGSDNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLRDLEDAD
190 200 210 220 230 240
CCDS99 LLIQLEAFEEAKAEDEEELLRVSGGVDMSSHQEVFASLFHKVSCSPVSAQLLSVLQGLLH
250 260 270 280 290 300
>>CCDS46429.1 FMNL2 gene_id:114793|Hs108|chr2 (1092 aa)
initn: 286 init1: 177 opt: 293 Z-score: 370.8 bits: 78.2 E(32554): 2.5e-14
Smith-Waterman score: 293; 34.1% identity (70.4% similar) in 135 aa overlap (101-234:224-357)
80 90 100 110 120 130
pF1KE6 QSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQ
:. :.::.:: . :.....:. : ...
CCDS46 RHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIAL
200 210 220 230 240 250
140 150 160 170 180 190
pF1KE6 ALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGSDN
.:...: .: :.:::::.:. :: . :.:.:..: ::... :: .:... . ::
CCDS46 SLNNKNPRTKALVLELLAAVCLVRG-GHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDN
260 270 280 290 300 310
200 210 220 230
pF1KE6 -VPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLR
. ..:. .. :: :. . ::. :..:. :: : : . : .:.
CCDS46 NIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYL
320 330 340 350 360 370
CCDS46 DNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNK
380 390 400 410 420 430
>>CCDS58323.1 DAAM1 gene_id:23002|Hs108|chr14 (1068 aa)
initn: 116 init1: 78 opt: 292 Z-score: 369.7 bits: 77.9 E(32554): 2.9e-14
Smith-Waterman score: 292; 30.0% identity (65.3% similar) in 190 aa overlap (53-234:137-321)
30 40 50 60 70 80
pF1KE6 SDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALA
:. :. . ....:.. .::. .:. :
CCDS58 IDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLK
110 120 130 140 150 160
90 100 110 120 130 140
pF1KE6 RLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQ
.. . :.. .. . ..:..:.::. :: ..:... . ..:.:.: :. .:
CCDS58 TMD----YETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVA
170 180 190 200 210 220
150 160 170 180 190
pF1KE6 VFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGS-----DNVPYVVTL
:.:.:.:.:. : :: .:.:. ::. :.. ::. ..:.:. : :.: ...
CCDS58 VLEILGAVCLV-PGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAI
230 240 250 260 270 280
200 210 220 230
pF1KE6 LSVINAVI---LGPEDLRARTQLRNEFIGLQLLDVLARLR
.: ::::. : :.: : .:: ::. : . :. .::
CCDS58 MSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNE
290 300 310 320 330 340
CCDS58 DELEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQY
350 360 370 380 390 400
>>CCDS9737.1 DAAM1 gene_id:23002|Hs108|chr14 (1078 aa)
initn: 116 init1: 78 opt: 292 Z-score: 369.6 bits: 77.9 E(32554): 2.9e-14
Smith-Waterman score: 292; 30.0% identity (65.3% similar) in 190 aa overlap (53-234:137-321)
30 40 50 60 70 80
pF1KE6 SDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALA
:. :. . ....:.. .::. .:. :
CCDS97 IDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLK
110 120 130 140 150 160
90 100 110 120 130 140
pF1KE6 RLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQ
.. . :.. .. . ..:..:.::. :: ..:... . ..:.:.: :. .:
CCDS97 TMD----YETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVA
170 180 190 200 210 220
150 160 170 180 190
pF1KE6 VFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGS-----DNVPYVVTL
:.:.:.:.:. : :: .:.:. ::. :.. ::. ..:.:. : :.: ...
CCDS97 VLEILGAVCLV-PGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAI
230 240 250 260 270 280
200 210 220 230
pF1KE6 LSVINAVI---LGPEDLRARTQLRNEFIGLQLLDVLARLR
.: ::::. : :.: : .:: ::. : . :. .::
CCDS97 MSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNE
290 300 310 320 330 340
CCDS97 DELEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQY
350 360 370 380 390 400
>>CCDS41780.1 FMNL3 gene_id:91010|Hs108|chr12 (976 aa)
initn: 235 init1: 161 opt: 291 Z-score: 369.1 bits: 77.7 E(32554): 3.1e-14
Smith-Waterman score: 320; 28.0% identity (59.2% similar) in 250 aa overlap (8-234:61-309)
10 20 30
pF1KE6 MSVKEGAQRKWAALKEKLGPQDSDPTEANLESA----
..:: . .. : ..: .. ...
CCDS41 PCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFL
40 50 60 70 80 90
40 50 60 70 80
pF1KE6 DPELCIRLLQMPSVVNYSGLRK---RLEGSDGGWMVQFL--EQSGLDLLLEALA------
:: . . .. . . ::. :. . ::. .:: :..:::.:.. :.
CCDS41 DPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSV
100 110 120 130 140 150
90 100 110 120 130
pF1KE6 ---RLSGRGVARISDALLQL----TCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTS
: :: . . : . : .:. :.::.:: . :.. ..:. : ... .:...
CCDS41 MYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNK
160 170 180 190 200 210
140 150 160 170 180 190
pF1KE6 NVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGSD-NVPYV
: .: :.:::::.:. :: . : :.:..: ::.. .:: .:. . . : :. ..
CCDS41 NPRTKALVLELLAAVCLVRG-GHEIILAAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFM
220 230 240 250 260
200 210 220 230
pF1KE6 VTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLR
:. .. :: :. . ::. :..:. :: : : . : . :
CCDS41 VACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFD
270 280 290 300 310 320
CCDS41 VGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESI
330 340 350 360 370 380
>>CCDS44874.1 FMNL3 gene_id:91010|Hs108|chr12 (1027 aa)
initn: 235 init1: 161 opt: 285 Z-score: 361.0 bits: 76.2 E(32554): 8.7e-14
Smith-Waterman score: 285; 34.1% identity (67.4% similar) in 135 aa overlap (101-234:227-360)
80 90 100 110 120 130
pF1KE6 QSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQ
:. :.::.:: . :.. ..:. : ...
CCDS44 RQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIAL
200 210 220 230 240 250
140 150 160 170 180
pF1KE6 ALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGSD-
.:...: .: :.:::::.:. :: . : :.:..: ::.. .:: .:. . . :
CCDS44 SLNNKNPRTKALVLELLAAVCLVRG-GHEIILAAFDNFKEVCKELHRFEKLMEYFRNEDS
260 270 280 290 300 310
190 200 210 220 230
pF1KE6 NVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLR
:. ..:. .. :: :. . ::. :..:. :: : : . : . :
CCDS44 NIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYL
320 330 340 350 360 370
CCDS44 DNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREK
380 390 400 410 420 430
>>CCDS11497.1 FMNL1 gene_id:752|Hs108|chr17 (1100 aa)
initn: 250 init1: 189 opt: 285 Z-score: 360.5 bits: 76.3 E(32554): 9.3e-14
Smith-Waterman score: 285; 34.8% identity (68.1% similar) in 135 aa overlap (101-234:230-363)
80 90 100 110 120 130
pF1KE6 QSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQ
:. :.::.:: ..:. .... . : ...
CCDS11 RHLTIKLTPAHSRKALRNSRIVSQKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIAL
200 210 220 230 240 250
140 150 160 170 180
pF1KE6 ALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGSD-
.:...: .: :.:::::.:. :: . : :.:..: ::..:.:: .:. . . :
CCDS11 SLNNKNPRTKALVLELLAAVCLVRG-GHDIILAAFDNFKEVCGEQHRFEKLMEYFRNEDS
260 270 280 290 300 310
190 200 210 220 230
pF1KE6 NVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLR
:. ..:. .. :: :. . :.. :. :. :: : : : :::
CCDS11 NIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYL
320 330 340 350 360 370
CCDS11 DNIFDVGALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARK
380 390 400 410 420 430
>>CCDS54999.1 DAAM2 gene_id:23500|Hs108|chr6 (1067 aa)
initn: 184 init1: 86 opt: 282 Z-score: 356.8 bits: 75.5 E(32554): 1.5e-13
Smith-Waterman score: 282; 30.0% identity (62.6% similar) in 190 aa overlap (53-234:133-317)
30 40 50 60 70 80
pF1KE6 SDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALA
:. :. . ....:.: :: ::. :
CCDS54 IDRINSMAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLR
110 120 130 140 150 160
90 100 110 120 130 140
pF1KE6 RLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQ
.. .. .. . ..:..:.::. :: ..:.. . ..:.: : : .:
CCDS54 SMDHA----TCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVA
170 180 190 200 210
150 160 170 180 190
pF1KE6 VFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGS-----DNVPYVVTL
:.:.:.:.:. : :: .:.:. ::.. ... ::. ..:::. : :.: ...
CCDS54 VLEILGAVCLV-PGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAI
220 230 240 250 260 270
200 210 220 230
pF1KE6 LSVINAVI---LGPEDLRARTQLRNEFIGLQLLDVLARLR
.: ::::. : ..:. : .:: ::. : . :. .::
CCDS54 MSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNE
280 290 300 310 320 330
CCDS54 DDLELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQ
340 350 360 370 380 390
234 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:07:28 2016 done: Tue Nov 8 15:07:28 2016
Total Scan time: 1.280 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]