FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6627, 220 aa
  1>>>pF1KE6627 220 - 220 aa - 220 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5527+/-0.000735; mu= 11.9059+/- 0.044
 mean_var=61.6740+/-11.939, 0's: 0 Z-trim(108.5): 7  B-trim: 0 in 0/50
 Lambda= 0.163314
 statistics sampled from 10276 (10282) to 10276 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.316), width:  16
 Scan time:  1.340

The best scores are:                                      opt bits E(32554)
CCDS11758.1 TIMP2 gene_id:7077|Hs108|chr17         ( 220) 1538 370.6 4.4e-103
CCDS2608.1 TIMP4 gene_id:7079|Hs108|chr3           ( 224)  780 192.0 2.6e-49
CCDS13911.1 TIMP3 gene_id:7078|Hs108|chr22         ( 211)  686 169.8 1.1e-42
CCDS14281.1 TIMP1 gene_id:7076|Hs108|chrX          ( 207)  554 138.7 2.6e-33


>>CCDS11758.1 TIMP2 gene_id:7077|Hs108|chr17              (220 aa)
 initn: 1538 init1: 1538 opt: 1538  Z-score: 1964.1  bits: 370.6 E(32554): 4.4e-103
Smith-Waterman score: 1538; 100.0% identity (100.0% similar) in 220 aa overlap (1-220:1-220)

               10        20        30        40        50        60
pF1KE6 MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGND
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 IYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 IYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 KMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTE
              130       140       150       160       170       180

              190       200       210       220
pF1KE6 KNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
       ::::::::::::::::::::::::::::::::::::::::
CCDS11 KNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
              190       200       210       220

>>CCDS2608.1 TIMP4 gene_id:7079|Hs108|chr3                (224 aa)
 initn: 812 init1: 564 opt: 780  Z-score: 998.8  bits: 192.0 E(32554): 2.6e-49
Smith-Waterman score: 780; 50.0% identity (80.2% similar) in 212 aa overlap (14-220:14-224)

               10        20           30        40        50       
pF1KE6 MGAAARTLRLALGLLLLATLLRP---ADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDS
                    :: : .::::   ..::::.:.:::: .:.. .:::::  ::: : .
CCDS26 MPGSPRPAPSWVLLLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVPA
               10        20        30        40        50        60

        60        70        80          90       100       110     
pF1KE6 GNDIYGNPIKRIQYEIKQIKMFKGPEK--DIEFIYTAPSSAVCGVSLDVGGKKEYLIAGK
       . :  ..  : ..::::::::::: ::  :...:::  .:..:::.:.....:.::..:.
CCDS26 SADP-ADTEKMLRYEIKQIKMFKGFEKVKDVQYIYTPFDSSLCGVKLEANSQKQYLLTGQ
                70        80        90       100       110         

         120       130       140       150       160       170     
pF1KE6 AEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWM
       . .:::. : ::..: ::. :: .:..::::.:...: :.:: :  .:: ::.:.:::: 
CCDS26 VLSDGKVFIHLCNYIEPWEDLSLVQRESLNHHYHLNCGCQITTCYTVPCTISAPNECLWT
     120       130       140       150       160       170         

         180       190       200       210       220
pF1KE6 DWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
       ::. :... :.::. ..:.:. ::.:.::::  : ..::.:: .:
CCDS26 DWLLERKLYGYQAQHYVCMKHVDGTCSWYRGHLPLRKEFVDIVQP
     180       190       200       210       220    

>>CCDS13911.1 TIMP3 gene_id:7078|Hs108|chr22              (211 aa)
 initn: 616 init1: 456 opt: 686  Z-score: 879.5  bits: 169.8 E(32554): 1.1e-42
Smith-Waterman score: 686; 45.2% identity (75.4% similar) in 199 aa overlap (24-220:21-211)

               10        20        30        40        50        60
pF1KE6 MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGND
                              :.::.::: :::.::::.:.:::::.:..: :  :  
CCDS13    MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEG--
                  10        20        30        40        50       

               70        80          90       100       110        
pF1KE6 IYGNPIKRIQYEIKQIKMFKGPEK--DIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEG
           :.  . : :::.::..:  :   ...:.:  : ..::..:.:. : .::..:..  
CCDS13 ----PFGTLVYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVN-KYQYLLTGRVY-
              60        70        80        90        100          

      120       130       140       150       160       170        
pF1KE6 DGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWV
       ::::.  ::.:.  :: :. .:.:.::.::..::.:::  : ..::...: .:::: : .
CCDS13 DGKMYTGLCNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDML
     110       120       130       140       150       160         

      180       190       200       210       220
pF1KE6 TEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
       .. .  :.:.: .:::... : :.:::: ::: . ...  ::
CCDS13 SNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP
     170       180       190       200       210 

>>CCDS14281.1 TIMP1 gene_id:7076|Hs108|chrX               (207 aa)
 initn: 547 init1: 199 opt: 554  Z-score: 711.6  bits: 138.7 E(32554): 2.6e-33
Smith-Waterman score: 554; 42.3% identity (67.2% similar) in 201 aa overlap (10-203:7-199)

               10        20        30        40        50        60
pF1KE6 MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGND
                :: :.:::  :. :. ::.: : ::: ::::.:.::::: :.  ::.. . 
CCDS14    MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQ-TT
                  10        20        30        40        50       

               70        80             90       100        110    
pF1KE6 IYGNPIKRIQYEIKQIKMFKGPEK-----DIEFIYTAPSSAVCGVSLDVGGK-KEYLIAG
       .:       .::::. ::.:: .      ::.:.::    .:::      .. .:.::::
CCDS14 LYQ------RYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAG
               60        70        80        90       100       110

          120       130       140       150        160       170   
pF1KE6 KAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCE-CKITRCPMIPCYISSPDECL
       : . :: .::: :.:..::..:: .:...... : .::: : .  :  ::: ..:  .::
CCDS14 KLQ-DGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCL
               120       130       140       150       160         

           180       190       200       210       220
pF1KE6 WMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
       : : . . . .: :.. .::. :  : :.:                 
CCDS14 WTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRSQIA         
     170       180       190       200                




220 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 14:55:04 2016 done: Tue Nov  8 14:55:04 2016
 Total Scan time:  1.340 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]