Result of FASTA (omim) for
pFN21AE6602
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6602, 238 aa
1>>>pF1KE6602 238 - 238 aa - 238 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8156+/-0.000292; mu= 17.1661+/- 0.018
mean_var=58.9631+/-11.475, 0's: 0 Z-trim(117.1): 21 B-trim: 0 in 0/54
Lambda= 0.167026
statistics sampled from 28746 (28767) to 28746 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.337), width: 16
Scan time: 4.370
The best scores are: opt bits E(85289)
NP_001186481 (OMIM: 612120,615238) cell death acti ( 238) 1574 387.0 1.5e-107
NP_001308071 (OMIM: 612120,615238) cell death acti ( 238) 1574 387.0 1.5e-107
NP_071377 (OMIM: 612120,615238) cell death activat ( 238) 1574 387.0 1.5e-107
NP_001186552 (OMIM: 612120,615238) cell death acti ( 251) 1574 387.0 1.6e-107
NP_001186480 (OMIM: 612120,615238) cell death acti ( 248) 1142 282.9 3.5e-76
NP_001308073 (OMIM: 612120,615238) cell death acti ( 164) 1111 275.3 4.4e-74
NP_001308072 (OMIM: 612120,615238) cell death acti ( 164) 1111 275.3 4.4e-74
NP_001270 (OMIM: 604440) cell death activator CIDE ( 219) 597 151.5 1.1e-36
NP_001305312 (OMIM: 604440) cell death activator C ( 253) 597 151.6 1.2e-36
NP_001305736 (OMIM: 604441) cell death activator C ( 219) 545 139.0 6.3e-33
XP_011534961 (OMIM: 604441) PREDICTED: cell death ( 219) 545 139.0 6.3e-33
NP_055245 (OMIM: 604441) cell death activator CIDE ( 219) 545 139.0 6.3e-33
XP_016876710 (OMIM: 604441) PREDICTED: cell death ( 219) 545 139.0 6.3e-33
NP_998731 (OMIM: 601882) DNA fragmentation factor ( 268) 162 46.8 4.5e-05
NP_004392 (OMIM: 601882) DNA fragmentation factor ( 331) 162 46.8 5.4e-05
>>NP_001186481 (OMIM: 612120,615238) cell death activato (238 aa)
initn: 1574 init1: 1574 opt: 1574 Z-score: 2051.6 bits: 387.0 E(85289): 1.5e-107
Smith-Waterman score: 1574; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238)
10 20 30 40 50 60
pF1KE6 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCGA
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 KRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
190 200 210 220 230
>>NP_001308071 (OMIM: 612120,615238) cell death activato (238 aa)
initn: 1574 init1: 1574 opt: 1574 Z-score: 2051.6 bits: 387.0 E(85289): 1.5e-107
Smith-Waterman score: 1574; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238)
10 20 30 40 50 60
pF1KE6 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCGA
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 KRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
190 200 210 220 230
>>NP_071377 (OMIM: 612120,615238) cell death activator C (238 aa)
initn: 1574 init1: 1574 opt: 1574 Z-score: 2051.6 bits: 387.0 E(85289): 1.5e-107
Smith-Waterman score: 1574; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:1-238)
10 20 30 40 50 60
pF1KE6 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCGA
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 KRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 KRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
190 200 210 220 230
>>NP_001186552 (OMIM: 612120,615238) cell death activato (251 aa)
initn: 1574 init1: 1574 opt: 1574 Z-score: 2051.3 bits: 387.0 E(85289): 1.6e-107
Smith-Waterman score: 1574; 100.0% identity (100.0% similar) in 238 aa overlap (1-238:14-251)
10 20 30 40
pF1KE6 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRV
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRNMESNAVQLTRMEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 STADRSVRKGIMAYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STADRSVRKGIMAYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 MVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE6 TYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKAS
190 200 210 220 230 240
230
pF1KE6 SLIPTCLKILQ
:::::::::::
NP_001 SLIPTCLKILQ
250
>>NP_001186480 (OMIM: 612120,615238) cell death activato (248 aa)
initn: 1142 init1: 1142 opt: 1142 Z-score: 1488.8 bits: 282.9 E(85289): 3.5e-76
Smith-Waterman score: 1544; 96.0% identity (96.0% similar) in 248 aa overlap (1-238:1-248)
10 20 30 40 50 60
pF1KE6 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMA
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 YSLEDLLLK----------VRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVL
::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 YSLEDLLLKTRNPEARSQEVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 QKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLI
190 200 210 220 230 240
pF1KE6 PTCLKILQ
::::::::
NP_001 PTCLKILQ
>>NP_001308073 (OMIM: 612120,615238) cell death activato (164 aa)
initn: 1111 init1: 1111 opt: 1111 Z-score: 1451.0 bits: 275.3 E(85289): 4.4e-74
Smith-Waterman score: 1111; 100.0% identity (100.0% similar) in 164 aa overlap (75-238:1-164)
50 60 70 80 90 100
pF1KE6 CRVSTADRSVRKGIMAYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGD
::::::::::::::::::::::::::::::
NP_001 MLADKPFFLVLEEDGTTVETEEYFQALAGD
10 20 30
110 120 130 140 150 160
pF1KE6 TVFMVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVFMVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKAT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 FYDTYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYDTYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKG
100 110 120 130 140 150
230
pF1KE6 KASSLIPTCLKILQ
::::::::::::::
NP_001 KASSLIPTCLKILQ
160
>>NP_001308072 (OMIM: 612120,615238) cell death activato (164 aa)
initn: 1111 init1: 1111 opt: 1111 Z-score: 1451.0 bits: 275.3 E(85289): 4.4e-74
Smith-Waterman score: 1111; 100.0% identity (100.0% similar) in 164 aa overlap (75-238:1-164)
50 60 70 80 90 100
pF1KE6 CRVSTADRSVRKGIMAYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGD
::::::::::::::::::::::::::::::
NP_001 MLADKPFFLVLEEDGTTVETEEYFQALAGD
10 20 30
110 120 130 140 150 160
pF1KE6 TVFMVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVFMVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKAT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 FYDTYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYDTYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKG
100 110 120 130 140 150
230
pF1KE6 KASSLIPTCLKILQ
::::::::::::::
NP_001 KASSLIPTCLKILQ
160
>>NP_001270 (OMIM: 604440) cell death activator CIDE-A i (219 aa)
initn: 595 init1: 310 opt: 597 Z-score: 779.8 bits: 151.5 E(85289): 1.1e-36
Smith-Waterman score: 597; 48.5% identity (74.2% similar) in 198 aa overlap (36-233:28-218)
10 20 30 40 50 60
pF1KE6 KSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRARPCRVSTADRSVRKGIMAYSLED
.: ::: :::. ::: :.:.:: ::..
NP_001 MEAARDYAGALIRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQE
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPPSEQGTR
:. :. :.:..: ::::::::.:.:::.::.:. .: ::.:.:::::.: :..
NP_001 LISKTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMP----GSQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 HPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCGAKRIMK
: . : : :. .::::::::.:::.:::::::::::.:. ::.:::..: : : ...
NP_001 HVPTCS--PPKRSGIARVTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLR
120 130 140 150 160 170
190 200 210 220 230
pF1KE6 EAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
.:. .: :.::. :. . :. ..:: :: ...:.. . ::
NP_001 SLLRFLSYSAQVTGQFLIYLGTYMLRVLDDKEERPSLRSQAKGRF-TCG
180 190 200 210
>>NP_001305312 (OMIM: 604440) cell death activator CIDE- (253 aa)
initn: 595 init1: 310 opt: 597 Z-score: 778.9 bits: 151.6 E(85289): 1.2e-36
Smith-Waterman score: 598; 45.7% identity (71.0% similar) in 221 aa overlap (13-233:42-252)
10 20 30 40
pF1KE6 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQLLSEPSPKAPRA
: :: .. : . . :. .: :
NP_001 NHNGSWAREGPRLGPSWKRGLWSPRGGPNRPAEPSRPLTFMGSQTKRVLF---TPLMHPA
20 30 40 50 60
50 60 70 80 90 100
pF1KE6 RPCRVSTADRSVRKGIMAYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALA
:: :::. ::: :.:.:: ::..:. :. :.:..: ::::::::.:.:::.::.:.
NP_001 RPFRVSNHDRSSRRGVMASSLQELISKTLDALVIATGLVTLVLEEDGTVVDTEEFFQTLG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 GDTVFMVLQKGQKWQPPSEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVK
.: ::.:.:::::.: :..: . : : :. .::::::::.:::.:::::::::
NP_001 DNTHFMILEKGQKWMP----GSQHVPTCS--PPKRSGIARVTFDLYRLNPKDFIGCLNVK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE6 ATFYDTYSLSYDLHCCGAKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPP
::.:. ::.:::..: : : ... .:. .: :.::. :. . :. ..:: ::
NP_001 ATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFLIYLGTYMLRVLDDKEERPSL
190 200 210 220 230 240
230
pF1KE6 KGKASSLIPTCLKILQ
...:.. . ::
NP_001 RSQAKGRF-TCG
250
>>NP_001305736 (OMIM: 604441) cell death activator CIDE- (219 aa)
initn: 532 init1: 261 opt: 545 Z-score: 712.1 bits: 139.0 E(85289): 6.3e-33
Smith-Waterman score: 545; 42.2% identity (68.4% similar) in 225 aa overlap (5-228:1-218)
10 20 30 40 50
pF1KE6 MEYAMKSLSLLYPKSLSRHVSVRTSVVTQQL-LSEPSPKAPRARPCRVSTADRSVRKGIM
:. :: : :..: : :: .: ... : : :. :: :: :..:::.
NP_001 MEYLSALNPSDLLRSVSNISSEFGRRVWTSAPPPQ----RPFRVCDHKRTIRKGLT
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 AYSLEDLLLKVRDTLMLADKPFFLVLEEDGTTVETEEYFQALAGDTVFMVLQKGQKWQPP
: . ..:: :. .::.: . . ::::::::.:..:..:: : :: .::::.::.:.:
NP_001 AATRQELLAKALETLLL-NGVLTLVLEEDGTAVDSEDFFQLLEDDTCLMVLQSGQSWSPT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 SEQGTRHPLSLSHKPAKKIDVARVTFDLYKLNPQDFIGCLNVKATFYDTYSLSYDLHCCG
. :. ..: .. :.:: :::.:: ::.:..: :::::::: ::.: :.. :
NP_001 RSGVLSYGLG-RERPKHSKDIARFTFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGLG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 AKRIMKEAFRWALFSMQATGHVLLGTSCYLQQLLDATEEGQPPKGKASSLIPTCLKILQ
:....: .::. .:. ::.::: : :.. ....:. : ::. :
NP_001 PKKVLRELLRWTSTLLQGLGHMLLGISSTLRHAVEGAEQWQQ-KGRLHSY
180 190 200 210
238 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:41:13 2016 done: Tue Nov 8 14:41:14 2016
Total Scan time: 4.370 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]