Result of FASTA (omim) for
pFN21AE6581
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6581, 132 aa
1>>>pF1KE6581 132 - 132 aa - 132 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3966+/-0.000468; mu= 9.8666+/- 0.029
mean_var=56.3210+/-11.543, 0's: 0 Z-trim(107.1): 29 B-trim: 5 in 1/50
Lambda= 0.170899
statistics sampled from 15154 (15181) to 15154 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.541), E-opt: 0.2 (0.178), width: 16
Scan time: 2.600
The best scores are: opt bits E(85289)
NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 843 216.3 1.1e-56
NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 280 77.5 6.9e-15
NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 264 73.6 1.1e-13
NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 258 72.1 3.6e-13
XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 251 70.4 9.3e-13
NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 248 69.6 1.6e-12
NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 238 67.2 9e-12
NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 236 66.7 1.3e-11
NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 227 64.5 6.1e-11
XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 227 64.5 6.1e-11
NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 227 64.5 6.1e-11
NP_001305971 (OMIM: 602965) fatty acid-binding pro ( 128) 206 59.3 2.1e-09
NP_001305970 (OMIM: 602965) fatty acid-binding pro ( 97) 194 56.3 1.2e-08
NP_001307925 (OMIM: 134651) fatty acid-binding pro ( 144) 195 56.6 1.5e-08
NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 192 55.9 3.4e-08
NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 185 54.1 7.8e-08
NP_001435 (OMIM: 605168) fatty acid-binding protei ( 135) 179 52.6 2.2e-07
NP_001436 (OMIM: 600422) gastrotropin isoform 2 [H ( 128) 171 50.6 8.2e-07
NP_001124430 (OMIM: 600422) gastrotropin isoform 1 ( 177) 171 50.7 1.1e-06
NP_001035532 (OMIM: 600422) gastrotropin isoform 1 ( 177) 171 50.7 1.1e-06
NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 159 47.7 6.7e-06
NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 143 43.8 0.00012
NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 137 42.3 0.00027
NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 138 42.5 0.00028
NP_113679 (OMIM: 611866) retinol-binding protein 5 ( 135) 127 39.8 0.0016
>>NP_000125 (OMIM: 134640) fatty acid-binding protein, i (132 aa)
initn: 843 init1: 843 opt: 843 Z-score: 1138.5 bits: 216.3 E(85289): 1.1e-56
Smith-Waterman score: 843; 99.2% identity (100.0% similar) in 132 aa overlap (1-132:1-132)
10 20 30 40 50 60
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_000 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSTFRNIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVY
70 80 90 100 110 120
130
pF1KE6 EGVEAKRIFKKD
::::::::::::
NP_000 EGVEAKRIFKKD
130
>>NP_001437 (OMIM: 602965) fatty acid-binding protein, b (132 aa)
initn: 270 init1: 227 opt: 280 Z-score: 388.3 bits: 77.5 E(85289): 6.9e-15
Smith-Waterman score: 280; 35.4% identity (70.8% similar) in 130 aa overlap (2-131:4-131)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRN
:: .:::. :.:.:..:. .::... :... . . :.:::.: ... :.:.:
NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTY
:. :.:: :. . :: . ... ::.:.::. .... : :.: : :::: ..:.:
NP_001 TEISFQLGEEFDETTADDRNCKSVVSLDGDKLV-HIQKWD-GKETNFVREIKDGKMVMTL
70 80 90 100 110
120 130
pF1KE6 VYEGVEAKRIFKKD
.. : : : ..:
NP_001 TFGDVVAVRHYEKA
120 130
>>NP_004093 (OMIM: 134651) fatty acid-binding protein, h (133 aa)
initn: 264 init1: 219 opt: 264 Z-score: 366.9 bits: 73.6 E(85289): 1.1e-13
Smith-Waterman score: 264; 32.8% identity (70.2% similar) in 131 aa overlap (2-132:4-132)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRN
:: .:::. :.:.: .:...::... :..:. . : ..:. .:.: :.:.:
NP_004 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTY
:. :.::: :. . :: .... .:.:.::. .... : :.: . :::.: .:. :
NP_004 TEISFKLGVEFDETTADDRKVKSIVTLDGGKLV-HLQKWD-GQETTLVRELIDGKLILTL
70 80 90 100 110
120 130
pF1KE6 VYEGVEAKRIFKKD
.. . : ..:.
NP_004 THGTAVCTRTYEKEA
120 130
>>NP_001305968 (OMIM: 602965) fatty acid-binding protein (166 aa)
initn: 270 init1: 227 opt: 258 Z-score: 357.3 bits: 72.1 E(85289): 3.6e-13
Smith-Waterman score: 258; 36.0% identity (71.9% similar) in 114 aa overlap (2-115:4-115)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRN
:: .:::. :.:.:..:. .::... :... . . :.:::.: ... :.:.:
NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTY
:. :.:: :. . :: . ... ::.:.::. .... : :.: : :::: ..:
NP_001 TEISFQLGEEFDETTADDRNCKSVVSLDGDKLV-HIQKWD-GKETNFVREIKDGKMVMVS
70 80 90 100 110
120 130
pF1KE6 VYEGVEAKRIFKKD
NP_001 NDNSPFFLVFFSSPHTSHLLPSSSLLLPFFLLPSFFNNTSLARFFNYM
120 130 140 150 160
>>XP_011539309 (OMIM: 134651) PREDICTED: fatty acid-bind (126 aa)
initn: 260 init1: 219 opt: 251 Z-score: 350.0 bits: 70.4 E(85289): 9.3e-13
Smith-Waterman score: 251; 35.1% identity (72.8% similar) in 114 aa overlap (2-115:4-115)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRN
:: .:::. :.:.: .:...::... :..:. . : ..:. .:.: :.:.:
XP_011 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTY
:. :.::: :. . :: .... .:.:.::. .... : :.: . :::.: .:.
XP_011 TEISFKLGVEFDETTADDRKVKSIVTLDGGKLV-HLQKWD-GQETTLVRELIDGKLILME
70 80 90 100 110
120 130
pF1KE6 VYEGVEAKRIFKKD
XP_011 KLQLRNVK
120
>>NP_001433 (OMIM: 600434) fatty acid-binding protein, a (132 aa)
initn: 240 init1: 214 opt: 248 Z-score: 345.7 bits: 69.6 E(85289): 1.6e-12
Smith-Waterman score: 248; 33.1% identity (67.7% similar) in 130 aa overlap (2-131:4-131)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRN
:: .:::. :::.: .:...::... ::.:. . .. :. .:. .:.: :.:.:
NP_001 MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTY
:. : :: :. :: ....: .:.:. :. : ... .. :: :.::
NP_001 TEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKRE--DDKLVVEC
70 80 90 100 110
120 130
pF1KE6 VYEGVEAKRIFKKD
:..:: . :....
NP_001 VMKGVTSTRVYERA
120 130
>>NP_002668 (OMIM: 170715) myelin P2 protein [Homo sapie (132 aa)
initn: 224 init1: 188 opt: 238 Z-score: 332.3 bits: 67.2 E(85289): 9e-12
Smith-Waterman score: 238; 31.0% identity (68.2% similar) in 129 aa overlap (3-131:5-131)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRN
: .:::. :::.: .:. .::... :::. . . :...:. .:.. :.:.:
NP_002 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTY
:. :.:: :. . ::. . .. .:. ..: .. .: : :.: . :.... ..:
NP_002 TEISFKLGQEFEETTADNRKTKSIVTLQRGSL-NQVQRWD-GKETTIKRKLVNGKMVAEC
70 80 90 100 110
120 130
pF1KE6 VYEGVEAKRIFKKD
..:: ::..:
NP_002 KMKGVVCTRIYEKV
120 130
>>NP_004369 (OMIM: 180230) cellular retinoic acid-bindin (137 aa)
initn: 168 init1: 98 opt: 236 Z-score: 329.4 bits: 66.7 E(85289): 1.3e-11
Smith-Waterman score: 236; 31.3% identity (63.4% similar) in 134 aa overlap (3-132:4-137)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLA--AHDNLKLTITQEGNKFTVKESSAFR
: .:::. :::.:.... .::: . ::.: : .. .. : :.:..: .: :.. :
NP_004 MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 NIEVVFELGVTFNYNLADGTELRG--TWSLEGNKLIGKFKRTDNGNELNTVREIIGDELV
. :. :..: :. . .:: . :. :: :.. . .: . .::. .:::.
NP_004 TTEINFKVGEGFEEETVDGRKCRSLATWENENKIHCTQTLLEGDGPKTYWTRELANDELI
70 80 90 100 110 120
120 130
pF1KE6 QTYVYEGVEAKRIFKKD
:. . : ::. ..
NP_004 LTFGADDVVCTRIYVRE
130
>>NP_001869 (OMIM: 180231) cellular retinoic acid-bindin (138 aa)
initn: 185 init1: 100 opt: 227 Z-score: 317.4 bits: 64.5 E(85289): 6.1e-11
Smith-Waterman score: 227; 30.9% identity (64.7% similar) in 136 aa overlap (3-132:4-138)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLK--LTITQEGNKFTVKESSAFR
:...::. ::::...... .:::.. ::.:. : . : :::. : .: :.. :
NP_001 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 NIEVVFELGVTFNYNLADGTELRGT--WSLEGNKLIGKFKRTDN-GNELNTVREIIGD-E
. :. :..: :. . .:: .. : : ::.. . : . : . . .::. .: :
NP_001 TTEINFKVGEEFEEQTVDGRPCKSLVKWESE-NKMVCEQKLLKGEGPKTSWTRELTNDGE
70 80 90 100 110
120 130
pF1KE6 LVQTYVYEGVEAKRIFKKD
:. :.. . : :.. ..
NP_001 LILTMTADDVVCTRVYVRE
120 130
>>XP_016855832 (OMIM: 180231) PREDICTED: cellular retino (138 aa)
initn: 185 init1: 100 opt: 227 Z-score: 317.4 bits: 64.5 E(85289): 6.1e-11
Smith-Waterman score: 227; 30.9% identity (64.7% similar) in 136 aa overlap (3-132:4-138)
10 20 30 40 50
pF1KE6 MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLK--LTITQEGNKFTVKESSAFR
:...::. ::::...... .:::.. ::.:. : . : :::. : .: :.. :
XP_016 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 NIEVVFELGVTFNYNLADGTELRGT--WSLEGNKLIGKFKRTDN-GNELNTVREIIGD-E
. :. :..: :. . .:: .. : : ::.. . : . : . . .::. .: :
XP_016 TTEINFKVGEEFEEQTVDGRPCKSLVKWESE-NKMVCEQKLLKGEGPKTSWTRELTNDGE
70 80 90 100 110
120 130
pF1KE6 LVQTYVYEGVEAKRIFKKD
:. :.. . : :.. ..
XP_016 LILTMTADDVVCTRVYVRE
120 130
132 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:34:39 2016 done: Tue Nov 8 14:34:40 2016
Total Scan time: 2.600 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]