Result of FASTA (omim) for
pFN21AE6580
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6580, 131 aa
1>>>pF1KE6580 131 - 131 aa - 131 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8980+/-0.000321; mu= 13.0596+/- 0.020
mean_var=59.7271+/-11.958, 0's: 0 Z-trim(115.0): 81 B-trim: 484 in 1/52
Lambda= 0.165954
statistics sampled from 25082 (25163) to 25082 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.295), width: 16
Scan time: 3.890
The best scores are: opt bits E(85289)
NP_001135917 (OMIM: 182900,612641) ankyrin-1 isofo ( 156) 788 196.5 1.2e-50
NP_065211 (OMIM: 182900,612641) ankyrin-1 isoform ( 155) 787 196.3 1.4e-50
NP_065213 (OMIM: 182900,612641) ankyrin-1 isoform ( 109) 654 164.3 4.1e-41
NP_065208 (OMIM: 182900,612641) ankyrin-1 isoform (1856) 384 100.5 1.2e-20
XP_011542804 (OMIM: 182900,612641) PREDICTED: anky (1889) 384 100.5 1.2e-20
NP_001135918 (OMIM: 182900,612641) ankyrin-1 isofo (1897) 384 100.5 1.2e-20
XP_011542798 (OMIM: 182900,612641) PREDICTED: anky (1944) 384 100.5 1.2e-20
NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform (1719) 325 86.3 2e-16
XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752) 325 86.3 2e-16
XP_016868817 (OMIM: 182900,612641) PREDICTED: anky (1792) 325 86.3 2.1e-16
XP_016868816 (OMIM: 182900,612641) PREDICTED: anky (1807) 325 86.3 2.1e-16
NP_065209 (OMIM: 182900,612641) ankyrin-1 isoform (1881) 325 86.3 2.1e-16
XP_016868814 (OMIM: 182900,612641) PREDICTED: anky (1908) 325 86.4 2.2e-16
XP_011542802 (OMIM: 182900,612641) PREDICTED: anky (1914) 325 86.4 2.2e-16
XP_016868813 (OMIM: 182900,612641) PREDICTED: anky (1922) 325 86.4 2.2e-16
XP_016868812 (OMIM: 182900,612641) PREDICTED: anky (1936) 325 86.4 2.2e-16
XP_016868811 (OMIM: 182900,612641) PREDICTED: anky (1937) 325 86.4 2.2e-16
XP_016868810 (OMIM: 182900,612641) PREDICTED: anky (1940) 325 86.4 2.2e-16
XP_011542796 (OMIM: 182900,612641) PREDICTED: anky (1954) 325 86.4 2.2e-16
XP_016868808 (OMIM: 182900,612641) PREDICTED: anky (1961) 325 86.4 2.2e-16
XP_011542792 (OMIM: 182900,612641) PREDICTED: anky (1969) 325 86.4 2.2e-16
XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751) 324 86.1 2.4e-16
XP_016868818 (OMIM: 182900,612641) PREDICTED: anky (1759) 324 86.1 2.4e-16
XP_011542805 (OMIM: 182900,612641) PREDICTED: anky (1791) 324 86.1 2.4e-16
NP_000028 (OMIM: 182900,612641) ankyrin-1 isoform (1880) 324 86.1 2.5e-16
XP_016868815 (OMIM: 182900,612641) PREDICTED: anky (1892) 324 86.1 2.5e-16
XP_011542803 (OMIM: 182900,612641) PREDICTED: anky (1913) 324 86.1 2.6e-16
XP_005273533 (OMIM: 182900,612641) PREDICTED: anky (1921) 324 86.1 2.6e-16
XP_011542797 (OMIM: 182900,612641) PREDICTED: anky (1953) 324 86.1 2.6e-16
XP_011542793 (OMIM: 182900,612641) PREDICTED: anky (1968) 324 86.1 2.6e-16
XP_016863582 (OMIM: 106410,600919) PREDICTED: anky (1881) 246 67.4 1.1e-10
XP_016863581 (OMIM: 106410,600919) PREDICTED: anky (1882) 246 67.4 1.1e-10
XP_016863577 (OMIM: 106410,600919) PREDICTED: anky (1893) 246 67.4 1.1e-10
XP_016863574 (OMIM: 106410,600919) PREDICTED: anky (1902) 246 67.4 1.1e-10
XP_016863573 (OMIM: 106410,600919) PREDICTED: anky (1915) 246 67.4 1.1e-10
XP_016863572 (OMIM: 106410,600919) PREDICTED: anky (1917) 246 67.4 1.1e-10
XP_016863570 (OMIM: 106410,600919) PREDICTED: anky (1931) 246 67.4 1.1e-10
XP_016863568 (OMIM: 106410,600919) PREDICTED: anky (2006) 246 67.5 1.1e-10
XP_016863566 (OMIM: 106410,600919) PREDICTED: anky (4074) 246 67.6 2e-10
XP_016863564 (OMIM: 106410,600919) PREDICTED: anky (4115) 246 67.6 2e-10
XP_016863563 (OMIM: 106410,600919) PREDICTED: anky (4127) 246 67.6 2e-10
XP_016863562 (OMIM: 106410,600919) PREDICTED: anky (4136) 246 67.6 2e-10
XP_016863561 (OMIM: 106410,600919) PREDICTED: anky (4137) 246 67.6 2e-10
XP_016863560 (OMIM: 106410,600919) PREDICTED: anky (4145) 246 67.6 2e-10
XP_016863559 (OMIM: 106410,600919) PREDICTED: anky (4163) 246 67.6 2e-10
XP_016863558 (OMIM: 106410,600919) PREDICTED: anky (4175) 246 67.6 2e-10
XP_016863557 (OMIM: 106410,600919) PREDICTED: anky (4181) 246 67.6 2e-10
XP_016863556 (OMIM: 106410,600919) PREDICTED: anky (4183) 246 67.6 2e-10
XP_016863598 (OMIM: 106410,600919) PREDICTED: anky (1770) 211 59.0 3.3e-08
XP_016868809 (OMIM: 182900,612641) PREDICTED: anky (1946) 198 56.0 3.1e-07
>>NP_001135917 (OMIM: 182900,612641) ankyrin-1 isoform 1 (156 aa)
initn: 787 init1: 787 opt: 788 Z-score: 1030.2 bits: 196.5 E(85289): 1.2e-50
Smith-Waterman score: 788; 96.1% identity (96.9% similar) in 129 aa overlap (1-129:1-129)
10 20 30 40 50 60
pF1KE6 MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQE
70 80 90 100 110 120
130
pF1KE6 HEEDHTSTPNP
::: . :
NP_001 HEEVTVEGPLEDPSELEVDIDYFMKHSKDHTSTPNP
130 140 150
>>NP_065211 (OMIM: 182900,612641) ankyrin-1 isoform 5 pr (155 aa)
initn: 787 init1: 787 opt: 787 Z-score: 1029.0 bits: 196.3 E(85289): 1.4e-50
Smith-Waterman score: 787; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:1-123)
10 20 30 40 50 60
pF1KE6 MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQE
70 80 90 100 110 120
130
pF1KE6 HEEDHTSTPNP
:::
NP_065 HEEVELRGSGLQPDLIEGRKGAQIVKRASLKRGKQ
130 140 150
>>NP_065213 (OMIM: 182900,612641) ankyrin-1 isoform 7 pr (109 aa)
initn: 654 init1: 654 opt: 654 Z-score: 859.1 bits: 164.3 E(85289): 4.1e-41
Smith-Waterman score: 660; 83.2% identity (83.2% similar) in 131 aa overlap (1-131:1-109)
10 20 30 40 50 60
pF1KE6 MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQE
:::::::::::::::::::::::::::::::::::::::::
NP_065 ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK-------------------
70 80 90 100
130
pF1KE6 HEEDHTSTPNP
::::::::
NP_065 ---DHTSTPNP
>>NP_065208 (OMIM: 182900,612641) ankyrin-1 isoform 4 [H (1856 aa)
initn: 380 init1: 380 opt: 384 Z-score: 491.8 bits: 100.5 E(85289): 1.2e-20
Smith-Waterman score: 384; 74.4% identity (87.2% similar) in 86 aa overlap (46-131:1778-1856)
20 30 40 50 60 70
pF1KE6 SFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGN
.. :. : ... ..:. :.:: .::
NP_065 QEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTF-TQVV------QGN
1750 1760 1770 1780 1790 1800
80 90 100 110 120 130
pF1KE6 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
1810 1820 1830 1840 1850
>>XP_011542804 (OMIM: 182900,612641) PREDICTED: ankyrin- (1889 aa)
initn: 380 init1: 380 opt: 384 Z-score: 491.7 bits: 100.5 E(85289): 1.2e-20
Smith-Waterman score: 384; 74.4% identity (87.2% similar) in 86 aa overlap (46-131:1811-1889)
20 30 40 50 60 70
pF1KE6 SFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGN
.. :. : ... ..:. :.:: .::
XP_011 QEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTF-TQVV------QGN
1790 1800 1810 1820 1830
80 90 100 110 120 130
pF1KE6 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
1840 1850 1860 1870 1880
>>NP_001135918 (OMIM: 182900,612641) ankyrin-1 isoform 9 (1897 aa)
initn: 380 init1: 380 opt: 384 Z-score: 491.7 bits: 100.5 E(85289): 1.2e-20
Smith-Waterman score: 384; 74.4% identity (87.2% similar) in 86 aa overlap (46-131:1819-1897)
20 30 40 50 60 70
pF1KE6 SFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGN
.. :. : ... ..:. :.:: .::
NP_001 QEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTF-TQVV------QGN
1790 1800 1810 1820 1830 1840
80 90 100 110 120 130
pF1KE6 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
1850 1860 1870 1880 1890
>>XP_011542798 (OMIM: 182900,612641) PREDICTED: ankyrin- (1944 aa)
initn: 380 init1: 380 opt: 384 Z-score: 491.5 bits: 100.5 E(85289): 1.2e-20
Smith-Waterman score: 384; 74.4% identity (87.2% similar) in 86 aa overlap (46-131:1866-1944)
20 30 40 50 60 70
pF1KE6 SFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGN
.. :. : ... ..:. :.:: .::
XP_011 QEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTF-TQVV------QGN
1840 1850 1860 1870 1880
80 90 100 110 120 130
pF1KE6 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
1890 1900 1910 1920 1930 1940
>>NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform 2 [H (1719 aa)
initn: 320 init1: 320 opt: 325 Z-score: 415.9 bits: 86.3 E(85289): 2e-16
Smith-Waterman score: 325; 67.9% identity (82.1% similar) in 84 aa overlap (46-129:1616-1692)
20 30 40 50 60 70
pF1KE6 SFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGN
.. :. : ... ..:. :.:: .::
NP_065 QEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTF-TQVV------QGN
1590 1600 1610 1620 1630
80 90 100 110 120 130
pF1KE6 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
:::::::::::::::::::::::::::::::::::::::::::::::: . :
NP_065 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEVTVEGPLEDPSE
1640 1650 1660 1670 1680 1690
NP_065 LEVDIDYFMKHSKDHTSTPNP
1700 1710
>>XP_011542806 (OMIM: 182900,612641) PREDICTED: ankyrin- (1752 aa)
initn: 320 init1: 320 opt: 325 Z-score: 415.8 bits: 86.3 E(85289): 2e-16
Smith-Waterman score: 325; 67.9% identity (82.1% similar) in 84 aa overlap (46-129:1649-1725)
20 30 40 50 60 70
pF1KE6 SFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGN
.. :. : ... ..:. :.:: .::
XP_011 QEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTF-TQVV------QGN
1620 1630 1640 1650 1660 1670
80 90 100 110 120 130
pF1KE6 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
:::::::::::::::::::::::::::::::::::::::::::::::: . :
XP_011 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEVTVEGPLEDPSE
1680 1690 1700 1710 1720 1730
XP_011 LEVDIDYFMKHSKDHTSTPNP
1740 1750
>>XP_016868817 (OMIM: 182900,612641) PREDICTED: ankyrin- (1792 aa)
initn: 320 init1: 320 opt: 325 Z-score: 415.7 bits: 86.3 E(85289): 2.1e-16
Smith-Waterman score: 325; 67.9% identity (82.1% similar) in 84 aa overlap (46-129:1689-1765)
20 30 40 50 60 70
pF1KE6 SFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGN
.. :. : ... ..:. :.:: .::
XP_016 QEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTF-TQVV------QGN
1660 1670 1680 1690 1700 1710
80 90 100 110 120 130
pF1KE6 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
:::::::::::::::::::::::::::::::::::::::::::::::: . :
XP_016 EFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEVTVEGPLEDPSE
1720 1730 1740 1750 1760 1770
XP_016 LEVDIDYFMKHSKDHTSTPNP
1780 1790
131 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:34:11 2016 done: Tue Nov 8 14:34:12 2016
Total Scan time: 3.890 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]