Result of FASTA (omim) for
pFN21AE6577
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6577, 71 aa
1>>>pF1KE6577 71 - 71 aa - 71 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5197+/-0.000241; mu= 11.4294+/- 0.015
mean_var=51.6292+/-10.318, 0's: 0 Z-trim(122.0): 10 B-trim: 446 in 1/52
Lambda= 0.178495
statistics sampled from 39338 (39348) to 39338 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.842), E-opt: 0.2 (0.461), width: 16
Scan time: 2.320
The best scores are: opt bits E(85289)
NP_001161407 (OMIM: 603284,607929) cerebral cavern ( 353) 441 120.4 1.3e-27
NP_113631 (OMIM: 603284,607929) cerebral cavernous ( 444) 441 120.4 1.5e-27
XP_011513864 (OMIM: 603284,607929) PREDICTED: cere ( 485) 441 120.4 1.6e-27
XP_016868160 (OMIM: 603284,607929) PREDICTED: cere ( 318) 377 103.8 1.1e-22
XP_006715849 (OMIM: 603284,607929) PREDICTED: cere ( 374) 377 103.9 1.2e-22
NP_001025006 (OMIM: 603284,607929) cerebral cavern ( 465) 377 104.0 1.4e-22
XP_011513863 (OMIM: 603284,607929) PREDICTED: cere ( 506) 377 104.0 1.5e-22
>>NP_001161407 (OMIM: 603284,607929) cerebral cavernous (353 aa)
initn: 441 init1: 441 opt: 441 Z-score: 617.0 bits: 120.4 E(85289): 1.3e-27
Smith-Waterman score: 441; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:1-68)
10 20 30 40 50 60
pF1KE6 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLS
10 20 30 40 50 60
70
pF1KE6 DYIEKEVKGSH
::::::::
NP_001 DYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNV
70 80 90 100 110 120
>>NP_113631 (OMIM: 603284,607929) cerebral cavernous mal (444 aa)
initn: 441 init1: 441 opt: 441 Z-score: 615.5 bits: 120.4 E(85289): 1.5e-27
Smith-Waterman score: 441; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:1-68)
10 20 30 40 50 60
pF1KE6 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLS
10 20 30 40 50 60
70
pF1KE6 DYIEKEVKGSH
::::::::
NP_113 DYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNV
70 80 90 100 110 120
>>XP_011513864 (OMIM: 603284,607929) PREDICTED: cerebral (485 aa)
initn: 441 init1: 441 opt: 441 Z-score: 615.0 bits: 120.4 E(85289): 1.6e-27
Smith-Waterman score: 441; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:1-68)
10 20 30 40 50 60
pF1KE6 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPERVEPDRLLS
10 20 30 40 50 60
70
pF1KE6 DYIEKEVKGSH
::::::::
XP_011 DYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNV
70 80 90 100 110 120
>>XP_016868160 (OMIM: 603284,607929) PREDICTED: cerebral (318 aa)
initn: 377 init1: 377 opt: 377 Z-score: 528.6 bits: 103.8 E(85289): 1.1e-22
Smith-Waterman score: 377; 98.3% identity (100.0% similar) in 59 aa overlap (10-68:31-89)
10 20 30
pF1KE6 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTER
.:::::::::::::::::::::::::::::
XP_016 MHSSCRQRRNQNLSKEIPQTEFHTGYSMENEPGIVSPFKRVFLKGEKSRDKKAHEKVTER
10 20 30 40 50 60
40 50 60 70
pF1KE6 RPLHTVVLSLPERVEPDRLLSDYIEKEVKGSH
:::::::::::::::::::::::::::::
XP_016 RPLHTVVLSLPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAH
70 80 90 100 110 120
>>XP_006715849 (OMIM: 603284,607929) PREDICTED: cerebral (374 aa)
initn: 377 init1: 377 opt: 377 Z-score: 527.5 bits: 103.9 E(85289): 1.2e-22
Smith-Waterman score: 377; 98.3% identity (100.0% similar) in 59 aa overlap (10-68:31-89)
10 20 30
pF1KE6 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTER
.:::::::::::::::::::::::::::::
XP_006 MHSSCRQRRNQNLSKEIPQTEFHTGYSMENEPGIVSPFKRVFLKGEKSRDKKAHEKVTER
10 20 30 40 50 60
40 50 60 70
pF1KE6 RPLHTVVLSLPERVEPDRLLSDYIEKEVKGSH
:::::::::::::::::::::::::::::
XP_006 RPLHTVVLSLPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAH
70 80 90 100 110 120
>>NP_001025006 (OMIM: 603284,607929) cerebral cavernous (465 aa)
initn: 377 init1: 377 opt: 377 Z-score: 526.2 bits: 104.0 E(85289): 1.4e-22
Smith-Waterman score: 377; 98.3% identity (100.0% similar) in 59 aa overlap (10-68:31-89)
10 20 30
pF1KE6 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTER
.:::::::::::::::::::::::::::::
NP_001 MHSSCRQRRNQNLSKEIPQTEFHTGYSMENEPGIVSPFKRVFLKGEKSRDKKAHEKVTER
10 20 30 40 50 60
40 50 60 70
pF1KE6 RPLHTVVLSLPERVEPDRLLSDYIEKEVKGSH
:::::::::::::::::::::::::::::
NP_001 RPLHTVVLSLPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAH
70 80 90 100 110 120
>>XP_011513863 (OMIM: 603284,607929) PREDICTED: cerebral (506 aa)
initn: 377 init1: 377 opt: 377 Z-score: 525.6 bits: 104.0 E(85289): 1.5e-22
Smith-Waterman score: 377; 98.3% identity (100.0% similar) in 59 aa overlap (10-68:31-89)
10 20 30
pF1KE6 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTER
.:::::::::::::::::::::::::::::
XP_011 MHSSCRQRRNQNLSKEIPQTEFHTGYSMENEPGIVSPFKRVFLKGEKSRDKKAHEKVTER
10 20 30 40 50 60
40 50 60 70
pF1KE6 RPLHTVVLSLPERVEPDRLLSDYIEKEVKGSH
:::::::::::::::::::::::::::::
XP_011 RPLHTVVLSLPERVEPDRLLSDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAH
70 80 90 100 110 120
71 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:32:46 2016 done: Tue Nov 8 14:32:46 2016
Total Scan time: 2.320 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]