FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6554, 152 aa
  1>>>pF1KE6554 152 - 152 aa - 152 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3745+/-0.00028; mu= 12.5945+/- 0.018
 mean_var=64.9762+/-13.347, 0's: 0 Z-trim(120.0): 22  B-trim: 566 in 1/52
 Lambda= 0.159110
 statistics sampled from 34692 (34714) to 34692 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.407), width:  16
 Scan time:  4.170

The best scores are:                                      opt bits E(85289)
NP_004139 (OMIM: 602062) ninjurin-1 [Homo sapiens] ( 152)  993 235.5 2.6e-62
XP_011517018 (OMIM: 602062) PREDICTED: ninjurin-1  ( 102)  632 152.5 1.6e-37
NP_001281274 (OMIM: 607297) ninjurin-2 isoform 2 [ ( 135)  431 106.4 1.6e-23
NP_057617 (OMIM: 607297) ninjurin-2 isoform 1 [Hom ( 188)  431 106.5 2.1e-23
NP_001281275 (OMIM: 607297) ninjurin-2 isoform 3 [ ( 106)  333 83.9 7.6e-17


>>NP_004139 (OMIM: 602062) ninjurin-1 [Homo sapiens]      (152 aa)
 initn: 993 init1: 993 opt: 993  Z-score: 1239.8  bits: 235.5 E(85289): 2.6e-62
Smith-Waterman score: 993; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)

               10        20        30        40        50        60
pF1KE6 MDSGTEEYELNGGLPPGTPGSPDASPARWGWRHGPINVNHYASKKSAAESMLDIALLMAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDSGTEEYELNGGLPPGTPGSPDASPARWGWRHGPINVNHYASKKSAAESMLDIALLMAN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 ASQLKAVVEQGPSFAFYVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASQLKAVVEQGPSFAFYVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNN
               70        80        90       100       110       120

              130       140       150  
pF1KE6 LATGLVFIIVVVNIFITAFGVQKPLMDMAPQQ
       ::::::::::::::::::::::::::::::::
NP_004 LATGLVFIIVVVNIFITAFGVQKPLMDMAPQQ
              130       140       150  

>>XP_011517018 (OMIM: 602062) PREDICTED: ninjurin-1 isof  (102 aa)
 initn: 632 init1: 632 opt: 632  Z-score: 794.6  bits: 152.5 E(85289): 1.6e-37
Smith-Waterman score: 632; 100.0% identity (100.0% similar) in 102 aa overlap (51-152:1-102)

               30        40        50        60        70        80
pF1KE6 SPDASPARWGWRHGPINVNHYASKKSAAESMLDIALLMANASQLKAVVEQGPSFAFYVPL
                                     ::::::::::::::::::::::::::::::
XP_011                               MLDIALLMANASQLKAVVEQGPSFAFYVPL
                                             10        20        30

               90       100       110       120       130       140
pF1KE6 VVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFG
               40        50        60        70        80        90

              150  
pF1KE6 VQKPLMDMAPQQ
       ::::::::::::
XP_011 VQKPLMDMAPQQ
              100  

>>NP_001281274 (OMIM: 607297) ninjurin-2 isoform 2 [Homo  (135 aa)
 initn: 455 init1: 421 opt: 431  Z-score: 543.4  bits: 106.4 E(85289): 1.6e-23
Smith-Waterman score: 431; 57.6% identity (80.8% similar) in 125 aa overlap (19-143:5-122)

               10        20        30        40        50        60
pF1KE6 MDSGTEEYELNGGLPPGTPGSPDASPARWGWRHGPINVNHYASKKSAAESMLDIALLMAN
                         ::: :  :     :  :::.::::.:::.::::::.::.:.:
NP_001               MMYMPGSSD--P-----RSQPINLNHYATKKSVAESMLDVALFMSN
                               10             20        30         

               70        80        90       100       110       120
pF1KE6 ASQLKAVVEQGPSFAFYVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNN
       : .::::.:::::  .:. ::.:::.::.::. .::::. ... .::.  :. .:. :::
NP_001 AMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNN
      40        50        60        70        80        90         

              130       140       150      
pF1KE6 LATGLVFIIVVVNIFITAFGVQKPLMDMAPQQ    
        :: :::. ::.:.::::::..:             
NP_001 AATILVFFTVVINVFITAFGAHKTGFLAARASRNPL
     100       110       120       130     

>>NP_057617 (OMIM: 607297) ninjurin-2 isoform 1 [Homo sa  (188 aa)
 initn: 455 init1: 421 opt: 431  Z-score: 541.2  bits: 106.5 E(85289): 2.1e-23
Smith-Waterman score: 432; 53.1% identity (76.9% similar) in 143 aa overlap (1-143:47-175)

                                             10        20        30
pF1KE6                               MDSGTEEYELNGGLPPGTPGSPDASPARWG
                                     :.:. :. .:.       ::: :  :    
NP_057 AAETQTAEPGGAHAVCSRHPVRVKGLEGSEMESARENIDLQ-------PGSSD--P----
         20        30        40        50               60         

               40        50        60        70        80        90
pF1KE6 WRHGPINVNHYASKKSAAESMLDIALLMANASQLKAVVEQGPSFAFYVPLVVLISISLVL
        :  :::.::::.:::.::::::.::.:.:: .::::.:::::  .:. ::.:::.::.:
NP_057 -RSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLL
             70        80        90       100       110       120  

              100       110       120       130       140       150
pF1KE6 QIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFGVQKPLMDMAP
       :. .::::. ... .::.  :. .:. ::: :: :::. ::.:.::::::..:       
NP_057 QVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAAR
            130       140       150       160       170       180  

             
pF1KE6 QQ    
             
NP_057 ASRNPL
             

>>NP_001281275 (OMIM: 607297) ninjurin-2 isoform 3 [Homo  (106 aa)
 initn: 351 init1: 333 opt: 333  Z-score: 423.4  bits: 83.9 E(85289): 7.6e-17
Smith-Waterman score: 333; 57.0% identity (84.9% similar) in 93 aa overlap (51-143:1-93)

               30        40        50        60        70        80
pF1KE6 SPDASPARWGWRHGPINVNHYASKKSAAESMLDIALLMANASQLKAVVEQGPSFAFYVPL
                                     :::.::.:.:: .::::.:::::  .:. :
NP_001                               MLDVALFMSNAMRLKAVLEQGPSSHYYTTL
                                             10        20        30

               90       100       110       120       130       140
pF1KE6 VVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFG
       :.:::.::.::. .::::. ... .::.  :. .:. ::: :: :::. ::.:.::::::
NP_001 VTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFG
               40        50        60        70        80        90

              150      
pF1KE6 VQKPLMDMAPQQ    
       ..:             
NP_001 AHKTGFLAARASRNPL
              100      




152 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 14:22:02 2016 done: Tue Nov  8 14:22:02 2016
 Total Scan time:  4.170 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]