Result of FASTA (omim) for
pFN21AE6553
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6553, 147 aa
1>>>pF1KE6553 147 - 147 aa - 147 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4365+/-0.000278; mu= 17.6138+/- 0.018
mean_var=69.1991+/-13.233, 0's: 0 Z-trim(119.5): 55 B-trim: 105 in 1/53
Lambda= 0.154179
statistics sampled from 33635 (33698) to 33635 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.395), width: 16
Scan time: 4.830
The best scores are: opt bits E(85289)
NP_001614 (OMIM: 601833) allograft inflammatory fa ( 147) 955 220.2 9.8e-58
NP_001305899 (OMIM: 601833) allograft inflammatory ( 93) 599 140.8 4.9e-34
NP_116573 (OMIM: 601833) allograft inflammatory fa ( 93) 599 140.8 4.9e-34
XP_005248927 (OMIM: 601833) PREDICTED: allograft i ( 186) 433 104.1 1e-22
XP_016865821 (OMIM: 601833) PREDICTED: allograft i ( 132) 347 84.9 4.7e-17
XP_005246057 (OMIM: 616450) PREDICTED: EF-hand dom ( 195) 158 43.0 0.00028
NP_077305 (OMIM: 616450) EF-hand domain-containing ( 240) 156 42.7 0.00044
NP_001230181 (OMIM: 611617) EF-hand domain-contain ( 143) 152 41.5 0.00057
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 152 41.7 0.0007
NP_079478 (OMIM: 611617) EF-hand domain-containing ( 239) 150 41.3 0.0011
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 146 40.2 0.0015
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 146 40.2 0.0015
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 146 40.2 0.0015
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 146 40.2 0.0015
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 146 40.2 0.0015
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 146 40.3 0.0016
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 137 38.3 0.0065
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 134 37.5 0.0093
>>NP_001614 (OMIM: 601833) allograft inflammatory factor (147 aa)
initn: 955 init1: 955 opt: 955 Z-score: 1157.5 bits: 220.2 E(85289): 9.8e-58
Smith-Waterman score: 955; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MSQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKM
70 80 90 100 110 120
130 140
pF1KE6 ILMYEEKAREKEKPTGPPAKKAISELP
:::::::::::::::::::::::::::
NP_001 ILMYEEKAREKEKPTGPPAKKAISELP
130 140
>>NP_001305899 (OMIM: 601833) allograft inflammatory fac (93 aa)
initn: 599 init1: 599 opt: 599 Z-score: 732.0 bits: 140.8 E(85289): 4.9e-34
Smith-Waterman score: 599; 100.0% identity (100.0% similar) in 93 aa overlap (55-147:1-93)
30 40 50 60 70 80
pF1KE6 DEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHL
::::::::::::::::::::::::::::::
NP_001 MEFDLNGNGDIDIMSLKRMLEKLGVPKTHL
10 20 30
90 100 110 120 130 140
pF1KE6 ELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAIS
40 50 60 70 80 90
pF1KE6 ELP
:::
NP_001 ELP
>>NP_116573 (OMIM: 601833) allograft inflammatory factor (93 aa)
initn: 599 init1: 599 opt: 599 Z-score: 732.0 bits: 140.8 E(85289): 4.9e-34
Smith-Waterman score: 599; 100.0% identity (100.0% similar) in 93 aa overlap (55-147:1-93)
30 40 50 60 70 80
pF1KE6 DEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHL
::::::::::::::::::::::::::::::
NP_116 MEFDLNGNGDIDIMSLKRMLEKLGVPKTHL
10 20 30
90 100 110 120 130 140
pF1KE6 ELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAIS
40 50 60 70 80 90
pF1KE6 ELP
:::
NP_116 ELP
>>XP_005248927 (OMIM: 601833) PREDICTED: allograft infla (186 aa)
initn: 766 init1: 433 opt: 433 Z-score: 528.7 bits: 104.1 E(85289): 1e-22
Smith-Waterman score: 598; 63.1% identity (63.1% similar) in 179 aa overlap (1-113:1-179)
10 20 30 40 50 60
pF1KE6 MSQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLN
10 20 30 40 50 60
pF1KE6 GNGDI-------------------------------------------------------
:::::
XP_005 GNGDIGEKRVICGGRVVCRPKKTEVSPTCSIPHDLGGGPPTTVGGRRMGMRKWERRERVS
70 80 90 100 110 120
70 80 90 100 110
pF1KE6 -----------DIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKR
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPSPHPHPLPPDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKR
130 140 150 160 170 180
120 130 140
pF1KE6 SAILKMILMYEEKAREKEKPTGPPAKKAISELP
XP_005 SAILKM
>>XP_016865821 (OMIM: 601833) PREDICTED: allograft infla (132 aa)
initn: 410 init1: 347 opt: 347 Z-score: 427.2 bits: 84.9 E(85289): 4.7e-17
Smith-Waterman score: 347; 100.0% identity (100.0% similar) in 55 aa overlap (66-120:78-132)
40 50 60 70 80 90
pF1KE6 KYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSS
::::::::::::::::::::::::::::::
XP_016 TVGGRRMGMRKWERRERVSPPSPHPHPLPPDIMSLKRMLEKLGVPKTHLELKKLIGEVSS
50 60 70 80 90 100
100 110 120 130 140
pF1KE6 GSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAISELP
:::::::::::::::::::::::::
XP_016 GSGETFSYPDFLRMMLGKRSAILKM
110 120 130
>>XP_005246057 (OMIM: 616450) PREDICTED: EF-hand domain- (195 aa)
initn: 121 init1: 121 opt: 158 Z-score: 197.9 bits: 43.0 E(85289): 0.00028
Smith-Waterman score: 158; 29.7% identity (63.4% similar) in 101 aa overlap (46-146:93-190)
20 30 40 50 60 70
pF1KE6 LKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLE
... ... . ..: . .: ::.: :: :.:
XP_005 ADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMME
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE6 KLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPT
:::.:.::: ::..: ::. .:. . . ...: .. . :.. :.:.
XP_005 KLGAPQTHLGLKNMIKEVDEDFDSKLSFREVQAINVSSR---FEEEIKAEQEERKKQAEE
130 140 150 160 170
140
pF1KE6 GPPAKKAISELP
: :..::
XP_005 MKQRKAAFKELQSTFK
180 190
>>NP_077305 (OMIM: 616450) EF-hand domain-containing pro (240 aa)
initn: 135 init1: 135 opt: 156 Z-score: 194.4 bits: 42.7 E(85289): 0.00044
Smith-Waterman score: 156; 36.6% identity (71.8% similar) in 71 aa overlap (46-116:93-162)
20 30 40 50 60 70
pF1KE6 LKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLE
... ... . ..: . .: ::.: :: :.:
NP_077 ADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMME
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE6 KLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPT
:::.:.::: ::..: ::. .:. .:: ... : .:
NP_077 KLGAPQTHLGLKNMIKEVDEDFDSKLSFREFL-LIFRKAAAGELQEDSGLCVLARLSEID
130 140 150 160 170 180
140
pF1KE6 GPPAKKAISELP
NP_077 VSSEGVKGAKSFFEAKVQAINVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQSTFK
190 200 210 220 230 240
>>NP_001230181 (OMIM: 611617) EF-hand domain-containing (143 aa)
initn: 133 init1: 133 opt: 152 Z-score: 192.3 bits: 41.5 E(85289): 0.00057
Smith-Waterman score: 152; 41.9% identity (72.6% similar) in 62 aa overlap (55-116:4-64)
30 40 50 60 70 80
pF1KE6 DEINKQFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHL
...: . .: ::.: :: :.::::.:.:::
NP_001 MGELQYDAGRDGFIDLMELKLMMEKLGAPQTHL
10 20 30
90 100 110 120 130 140
pF1KE6 ELKKLIGEVSSGSGETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAIS
::..: ::. .:. .:: ... : .:
NP_001 GLKSMIKEVDEDFDGKLSFREFL-LIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGA
40 50 60 70 80 90
pF1KE6 ELP
NP_001 KNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
100 110 120 130 140
>>NP_001292553 (OMIM: 114182,616249) calmodulin isoform (197 aa)
initn: 246 init1: 141 opt: 152 Z-score: 190.6 bits: 41.7 E(85289): 0.0007
Smith-Waterman score: 152; 32.2% identity (64.4% similar) in 87 aa overlap (27-113:39-124)
10 20 30 40 50
pF1KE6 MSQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFKEKYME
: ..: ..: ..:. .. ::: .
NP_001 RISPSGESELSGCVVASRKPVALAAWLALYIASHFAQQPC-KADQLTEEQIAEFKEAFSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMMLGKRSA
:: .:.: : : ....:: :. ::. .:.::.. .. :...:.:: :: :
NP_001 FDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKD
70 80 90 100 110 120
120 130 140
pF1KE6 ILKMILMYEEKAREKEKPTGPPAKKAISELP
NP_001 TDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNY
130 140 150 160 170 180
>>NP_079478 (OMIM: 611617) EF-hand domain-containing pro (239 aa)
initn: 153 init1: 133 opt: 150 Z-score: 187.2 bits: 41.3 E(85289): 0.0011
Smith-Waterman score: 150; 33.9% identity (62.4% similar) in 109 aa overlap (16-116:55-160)
10 20 30 40
pF1KE6 MSQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPK----YSSDE
:.:: .::: ::. :. ..
NP_079 QLAPLGAPAPEPKPEPEPPARAPTASADAELSAQLSRRLD-INEG-AARPRRCRVFNPYT
30 40 50 60 70 80
50 60 70 80 90
pF1KE6 DLP--SK--LEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGS
..: :. .. .. . .: . .: ::.: :: :.::::.:.::: ::..: ::.
NP_079 EFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDF
90 100 110 120 130 140
100 110 120 130 140
pF1KE6 GETFSYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAISELP
.:. .:: ... : .:
NP_079 DGKLSFREFL-LIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSS
150 160 170 180 190 200
147 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:21:34 2016 done: Tue Nov 8 14:21:35 2016
Total Scan time: 4.830 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]