Result of FASTA (ccds) for
pFN21AE6518
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6518, 195 aa
1>>>pF1KE6518 195 - 195 aa - 195 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2508+/-0.000695; mu= 7.4637+/- 0.043
mean_var=146.9134+/-29.488, 0's: 0 Z-trim(115.6): 39 B-trim: 0 in 0/54
Lambda= 0.105814
statistics sampled from 16100 (16139) to 16100 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.496), width: 16
Scan time: 2.050
The best scores are: opt bits E(32554)
CCDS2746.1 MYL3 gene_id:4634|Hs108|chr3 ( 195) 1301 208.7 1.9e-54
CCDS11510.1 MYL4 gene_id:4635|Hs108|chr17 ( 197) 1051 170.5 5.8e-43
CCDS2390.1 MYL1 gene_id:4632|Hs108|chr2 ( 194) 885 145.2 2.4e-35
CCDS8905.1 MYL6B gene_id:140465|Hs108|chr12 ( 208) 808 133.5 8.9e-32
CCDS8906.1 MYL6 gene_id:4637|Hs108|chr12 ( 151) 752 124.8 2.6e-29
CCDS2391.1 MYL1 gene_id:4632|Hs108|chr2 ( 150) 735 122.2 1.6e-28
CCDS31834.1 MYL6 gene_id:4637|Hs108|chr12 ( 151) 723 120.4 5.6e-28
CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 ( 149) 387 69.1 1.5e-12
CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 ( 149) 382 68.3 2.6e-12
CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 ( 149) 382 68.3 2.6e-12
CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 ( 149) 382 68.3 2.6e-12
>>CCDS2746.1 MYL3 gene_id:4634|Hs108|chr3 (195 aa)
initn: 1301 init1: 1301 opt: 1301 Z-score: 1091.1 bits: 208.7 E(32554): 1.9e-54
Smith-Waterman score: 1301; 99.5% identity (100.0% similar) in 195 aa overlap (1-195:1-195)
10 20 30 40 50 60
pF1KE6 MAPEKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFML
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFML
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 FDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN
130 140 150 160 170 180
190
pF1KE6 GCINYEAFVKHIMSS
:::::::::::::::
CCDS27 GCINYEAFVKHIMSS
190
>>CCDS11510.1 MYL4 gene_id:4635|Hs108|chr17 (197 aa)
initn: 987 init1: 987 opt: 1051 Z-score: 884.8 bits: 170.5 E(32554): 5.8e-43
Smith-Waterman score: 1051; 80.1% identity (90.8% similar) in 196 aa overlap (1-194:1-196)
10 20 30 40 50
pF1KE6 MAPEKPEPKKDDAKAAPKAAPAPAP-P-PEPERPKEVEFDASKIKIEFTPEQIEEFKEAF
:::.::::::. :: :: :::::: : : :: ::: :: ...::.:: .:::::::::
CCDS11 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 MLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPML
:::::: :::::::::::::::::::::.::::::::::. ::.:.::.:::::::.:
CCDS11 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 QHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQED
::::.::. ::::::::::::::::.::::::::::::::::::..:: :::.:.:::::
CCDS11 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
130 140 150 160 170 180
180 190
pF1KE6 SNGCINYEAFVKHIMSS
.:::::::::::::::
CCDS11 ANGCINYEAFVKHIMSG
190
>>CCDS2390.1 MYL1 gene_id:4632|Hs108|chr2 (194 aa)
initn: 706 init1: 706 opt: 885 Z-score: 748.0 bits: 145.2 E(32554): 2.4e-35
Smith-Waterman score: 885; 71.8% identity (83.1% similar) in 195 aa overlap (1-194:1-193)
10 20 30 40 50
pF1KE6 MAPEKPEPKK-DDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFM
:::.: : : ::: :::::: : : .::: ..: : :::::. :: .::::::.
CCDS23 MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 LFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQ
::::: . ::: .: :::::::: :::.::: .:::.: .::::.: ..:: ::::.:
CCDS23 LFDRTG--DSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQ
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 HISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDS
::.::: .::::::::::::::::::::::::::::::::::.. :.::: ::::::::
CCDS23 AISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDS
120 130 140 150 160 170
180 190
pF1KE6 NGCINYEAFVKHIMSS
:::::::::::::::
CCDS23 NGCINYEAFVKHIMSI
180 190
>>CCDS8905.1 MYL6B gene_id:140465|Hs108|chr12 (208 aa)
initn: 864 init1: 647 opt: 808 Z-score: 684.0 bits: 133.5 E(32554): 8.9e-32
Smith-Waterman score: 808; 63.4% identity (82.7% similar) in 191 aa overlap (5-194:19-207)
10 20 30 40
pF1KE6 MAPEKPEPKKDDAKAAP-KAAPAPAPPPEPERPKEVEFDASKIKIE
:: : : : : :. :: : :.. .: : ::. ::
CCDS89 MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN
:. .:.::::::: ::::. . :: :.:::::.::::::::.::::.:::.:...::.
CCDS89 FNKDQLEEFKEAFELFDRVG--DGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELK
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT
.. .:::::::::: ..::. :::::..::.::::::::: ::::::::::.::::..:
CCDS89 SRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMT
120 130 140 150 160 170
170 180 190
pF1KE6 EDEVEKLMAGQEDSNGCINYEAFVKHIMSS
:.::: ..::.::::::::::::.:::.:
CCDS89 EEEVETVLAGHEDSNGCINYEAFLKHILSV
180 190 200
>>CCDS8906.1 MYL6 gene_id:4637|Hs108|chr12 (151 aa)
initn: 841 init1: 676 opt: 752 Z-score: 639.7 bits: 124.8 E(32554): 2.6e-29
Smith-Waterman score: 752; 73.3% identity (92.0% similar) in 150 aa overlap (45-194:3-150)
20 30 40 50 60 70
pF1KE6 AAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYG
.:: .: ::::::.::::: . :: :.
CCDS89 MCDFTEDQTAEFKEAFQLFDRTG--DGKILYS
10 20 30
80 90 100 110 120 130
pF1KE6 QCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFV
:::::.::::::::.::::.:::.:...:.:.:..::: :::::: ..:::: :::::.:
CCDS89 QCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYV
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE6 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMS
::::::::::::::::::.::::.::::..::.::: :.::.:::::::::::::.::.:
CCDS89 EGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILS
100 110 120 130 140 150
pF1KE6 S
CCDS89 G
>>CCDS2391.1 MYL1 gene_id:4632|Hs108|chr2 (150 aa)
initn: 653 init1: 653 opt: 735 Z-score: 625.7 bits: 122.2 E(32554): 1.6e-28
Smith-Waterman score: 735; 75.5% identity (88.1% similar) in 151 aa overlap (44-194:1-149)
20 30 40 50 60 70
pF1KE6 KAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITY
. :. .:: ::::::.::::: . :::
CCDS23 MSFSADQIAEFKEAFLLFDRTG--DSKITL
10 20
80 90 100 110 120 130
pF1KE6 GQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDF
.: :::::::: :::.::: .:::.: .::::.: ..:: ::::.: ::.::: .:::::
CCDS23 SQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDF
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE6 VEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIM
:::::::::::::::::::::::::::::.. :.::: ::::::::::::::::::::::
CCDS23 VEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIM
90 100 110 120 130 140
pF1KE6 SS
:
CCDS23 SI
150
>>CCDS31834.1 MYL6 gene_id:4637|Hs108|chr12 (151 aa)
initn: 812 init1: 647 opt: 723 Z-score: 615.8 bits: 120.4 E(32554): 5.6e-28
Smith-Waterman score: 723; 70.0% identity (90.7% similar) in 150 aa overlap (45-194:3-150)
20 30 40 50 60 70
pF1KE6 AAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYG
.:: .: ::::::.::::: . :: :.
CCDS31 MCDFTEDQTAEFKEAFQLFDRTG--DGKILYS
10 20 30
80 90 100 110 120 130
pF1KE6 QCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFV
:::::.::::::::.::::.:::.:...:.:.:..::: :::::: ..:::: :::::.:
CCDS31 QCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYV
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE6 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMS
::::::::::::::::::.::::.::::..::.::: :.::.:::::::::: .:. ...
CCDS31 EGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEELVRMVLN
100 110 120 130 140 150
pF1KE6 S
CCDS31 G
>>CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 (149 aa)
initn: 415 init1: 180 opt: 387 Z-score: 338.7 bits: 69.1 E(32554): 1.5e-12
Smith-Waterman score: 387; 44.7% identity (73.7% similar) in 152 aa overlap (45-194:4-148)
20 30 40 50 60 70
pF1KE6 AAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPK-CEMKITY
..: ::. :::::: :::. : ::
CCDS70 MADQLTEEQVTEFKEAFSLFDKDGDGC---ITT
10 20 30
80 90 100 110 120 130
pF1KE6 GQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDF
. : :.:.::::::.::. .... .. .: .:: :: :. . : ::: . :..
CCDS70 RELGTVMRSLGQNPTEAELRDMMSEIDRDGNGT--VDFPEFLGMMAR--KMKDTDNEEEI
40 50 60 70 80
140 150 160 170 180 190
pF1KE6 VEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEAFVKHI
:..:::::.::: : .::::::.. :::.:...::.... :.. :..: .::: ::. .
CCDS70 REAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVL
90 100 110 120 130 140
pF1KE6 MSS
.:
CCDS70 VSK
>>CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 (149 aa)
initn: 421 init1: 185 opt: 382 Z-score: 334.5 bits: 68.3 E(32554): 2.6e-12
Smith-Waterman score: 382; 44.3% identity (72.5% similar) in 149 aa overlap (45-192:4-146)
20 30 40 50 60 70
pF1KE6 AAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYG
..: ::: :::::: :::. . ::
CCDS18 MADQLTEEQIAEFKEAFSLFDKDG--DGTITTK
10 20 30
80 90 100 110 120 130
pF1KE6 QCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFV
. : :.:.::::::.::. .... . .: .:: :: :. . : ::: . :..
CCDS18 ELGTVMRSLGQNPTEAELQDMINEVDADGNGT--IDFPEFLTMMAR--KMKDTDSEEEIR
40 50 60 70 80
140 150 160 170 180 190
pF1KE6 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIM
:..:::::.::: . .::::::...:::.::..::.... . :..: .::: ::. .
CCDS18 EAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT
90 100 110 120 130 140
pF1KE6 SS
CCDS18 AK
>>CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 (149 aa)
initn: 421 init1: 185 opt: 382 Z-score: 334.5 bits: 68.3 E(32554): 2.6e-12
Smith-Waterman score: 382; 44.3% identity (72.5% similar) in 149 aa overlap (45-192:4-146)
20 30 40 50 60 70
pF1KE6 AAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYG
..: ::: :::::: :::. . ::
CCDS33 MADQLTEEQIAEFKEAFSLFDKDG--DGTITTK
10 20 30
80 90 100 110 120 130
pF1KE6 QCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFV
. : :.:.::::::.::. .... . .: .:: :: :. . : ::: . :..
CCDS33 ELGTVMRSLGQNPTEAELQDMINEVDADGNGT--IDFPEFLTMMAR--KMKDTDSEEEIR
40 50 60 70 80
140 150 160 170 180 190
pF1KE6 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIM
:..:::::.::: . .::::::...:::.::..::.... . :..: .::: ::. .
CCDS33 EAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT
90 100 110 120 130 140
pF1KE6 SS
CCDS33 AK
195 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:02:20 2016 done: Tue Nov 8 14:02:20 2016
Total Scan time: 2.050 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]