Result of FASTA (omim) for
pFN21AE6516
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6516, 185 aa
1>>>pF1KE6516 185 - 185 aa - 185 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2480+/-0.000295; mu= 14.0622+/- 0.018
mean_var=68.7144+/-13.939, 0's: 0 Z-trim(118.3): 29 B-trim: 0 in 0/54
Lambda= 0.154721
statistics sampled from 31062 (31091) to 31062 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.365), width: 16
Scan time: 5.740
The best scores are: opt bits E(85289)
NP_001180389 (OMIM: 613718,613719) methionine-R-su ( 185) 1277 293.1 1.7e-79
NP_001026849 (OMIM: 613718,613719) methionine-R-su ( 185) 1277 293.1 1.7e-79
NP_001180390 (OMIM: 613718,613719) methionine-R-su ( 185) 1277 293.1 1.7e-79
NP_932346 (OMIM: 613718,613719) methionine-R-sulfo ( 192) 1119 257.9 7.1e-69
NP_036360 (OMIM: 613782) methionine-R-sulfoxide re ( 182) 466 112.1 5.1e-25
NP_057416 (OMIM: 606216) methionine-R-sulfoxide re ( 116) 289 72.5 2.8e-13
XP_011517728 (OMIM: 613782) PREDICTED: methionine- ( 141) 207 54.2 1.1e-07
>>NP_001180389 (OMIM: 613718,613719) methionine-R-sulfox (185 aa)
initn: 1277 init1: 1277 opt: 1277 Z-score: 1548.4 bits: 293.1 E(85289): 1.7e-79
Smith-Waterman score: 1277; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KE6 MSAFNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAFNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFTDDFSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFTDDFSYG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 MHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVASPAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVASPAQA
130 140 150 160 170 180
pF1KE6 DKAEL
:::::
NP_001 DKAEL
>>NP_001026849 (OMIM: 613718,613719) methionine-R-sulfox (185 aa)
initn: 1277 init1: 1277 opt: 1277 Z-score: 1548.4 bits: 293.1 E(85289): 1.7e-79
Smith-Waterman score: 1277; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KE6 MSAFNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAFNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFTDDFSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFTDDFSYG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 MHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVASPAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVASPAQA
130 140 150 160 170 180
pF1KE6 DKAEL
:::::
NP_001 DKAEL
>>NP_001180390 (OMIM: 613718,613719) methionine-R-sulfox (185 aa)
initn: 1277 init1: 1277 opt: 1277 Z-score: 1548.4 bits: 293.1 E(85289): 1.7e-79
Smith-Waterman score: 1277; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KE6 MSAFNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAFNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFTDDFSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFTDDFSYG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 MHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVASPAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVASPAQA
130 140 150 160 170 180
pF1KE6 DKAEL
:::::
NP_001 DKAEL
>>NP_932346 (OMIM: 613718,613719) methionine-R-sulfoxide (192 aa)
initn: 1119 init1: 1119 opt: 1119 Z-score: 1357.5 bits: 257.9 E(85289): 7.1e-69
Smith-Waterman score: 1119; 100.0% identity (100.0% similar) in 161 aa overlap (25-185:32-192)
10 20 30 40 50
pF1KE6 MSAFNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHV
::::::::::::::::::::::::::::::
NP_932 SPRRTLPRPLSLCLSLCLCLCLAAALGSAQSGSCRDKKNCKVVFSQQELRKRLTPLQYHV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 TQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 TQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 DDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 DDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGV
130 140 150 160 170 180
180
pF1KE6 ASPAQADKAEL
:::::::::::
NP_932 ASPAQADKAEL
190
>>NP_036360 (OMIM: 613782) methionine-R-sulfoxide reduct (182 aa)
initn: 454 init1: 247 opt: 466 Z-score: 570.1 bits: 112.1 E(85289): 5.1e-25
Smith-Waterman score: 466; 49.6% identity (74.1% similar) in 135 aa overlap (34-161:45-179)
10 20 30 40 50 60
pF1KE6 FNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESA
:.. ....: .:.::: :..::.:::::
NP_036 TAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTPEQFYVTREKGTEPP
20 30 40 50 60 70
70 80 90 100 110
pF1KE6 FEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSF---HDVINSE----AITFTDD
: : : ..:. :.:.:: : .:::.:: :. ::.::::: : . .:. .: :
NP_036 FSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTSGSDESHTGILRRLD
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE6 FSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVAS
: : :.:. :.:: :::::.: ::: :.:.:.::::.::.: :
NP_036 TSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPRKH
140 150 160 170 180
180
pF1KE6 PAQADKAEL
>>NP_057416 (OMIM: 606216) methionine-R-sulfoxide reduct (116 aa)
initn: 242 init1: 191 opt: 289 Z-score: 359.4 bits: 72.5 E(85289): 2.8e-13
Smith-Waterman score: 289; 36.6% identity (70.5% similar) in 112 aa overlap (62-171:5-115)
40 50 60 70 80 90
pF1KE6 KNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGE-YTHHKDPGIYKCVVCGTPLFKSE
: : :: . .: .::.: :. :: ::.:.
NP_057 MSFCSFFGGEVFQNHFEPGVYVCAKCGYELFSSR
10 20 30
100 110 120 130 140
pF1KE6 TKFDSGSGWPSFHDVINSEAITFTDDFSYGMHRVETSCSQCGAHLGHIF-DDGPRPTGKR
.:. .: ::.: ..:...... . . . . ...::..:: ::: : .:::.: .:
NP_057 SKYAHSSPWPAFTETIHADSVAKRPEHNRS-EALKVSCGKCGNGLGHEFLNDGPKPGQSR
40 50 60 70 80 90
150 160 170 180
pF1KE6 YCINSAALSFTPADSSGTAEGGSGVASPAQADKAEL
.:: :..:.:.: . .: :
NP_057 FCIFSSSLKFVPKGKETSASQGH
100 110
>>XP_011517728 (OMIM: 613782) PREDICTED: methionine-R-su (141 aa)
initn: 177 init1: 177 opt: 207 Z-score: 259.3 bits: 54.2 E(85289): 1.1e-07
Smith-Waterman score: 207; 48.2% identity (80.4% similar) in 56 aa overlap (34-89:45-100)
10 20 30 40 50 60
pF1KE6 FNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESA
:.. ....: .:.::: :..::.:::::
XP_011 TAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTPEQFYVTREKGTEPP
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE6 FEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVINSEAITFTDDFSYGMHR
: : : ..:. :.:.:: : .:::.:
XP_011 FSGIYLNNKEAGMYHCVCCDSPLFRSLLDIQKEVFSIKGSRSPSTSRGNGFDSEGAVRTI
80 90 100 110 120 130
185 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:01:02 2016 done: Tue Nov 8 14:01:02 2016
Total Scan time: 5.740 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]