Result of FASTA (omim) for
pFN21AE6509
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6509, 176 aa
1>>>pF1KE6509 176 - 176 aa - 176 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1887+/-0.000345; mu= 12.7876+/- 0.021
mean_var=56.6701+/-11.827, 0's: 0 Z-trim(114.6): 6 B-trim: 886 in 1/49
Lambda= 0.170372
statistics sampled from 24550 (24556) to 24550 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.288), width: 16
Scan time: 4.060
The best scores are: opt bits E(85289)
NP_036541 (OMIM: 604263) prion-like protein doppel ( 176) 1229 309.9 1.4e-84
NP_001073592 (OMIM: 123400,137440,176640,245300,60 ( 253) 151 45.0 0.00011
NP_001073590 (OMIM: 123400,137440,176640,245300,60 ( 253) 151 45.0 0.00011
NP_000302 (OMIM: 123400,137440,176640,245300,60007 ( 253) 151 45.0 0.00011
NP_898902 (OMIM: 123400,137440,176640,245300,60007 ( 253) 151 45.0 0.00011
NP_001073591 (OMIM: 123400,137440,176640,245300,60 ( 253) 151 45.0 0.00011
>>NP_036541 (OMIM: 604263) prion-like protein doppel pre (176 aa)
initn: 1229 init1: 1229 opt: 1229 Z-score: 1639.7 bits: 309.9 E(85289): 1.4e-84
Smith-Waterman score: 1229; 99.4% identity (99.4% similar) in 176 aa overlap (1-176:1-176)
10 20 30 40 50 60
pF1KE6 MRKHLSWWWLATVCMLLFSHLSAVQTRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MRKHLSWWWLATVCMLLFSHLSAVQTRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KQGRKLDIDFGAEGNRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINATQAANQGEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KQGRKLDIDFGAEGNRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINATQAANQGEF
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QKPDNKLHQQVLWRLVQELCSLKHCEFWLERGAGLRVTMHQPVLLCLLALIWLMVK
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_036 QKPDNKLHQQVLWRLVQELCSLKHCEFWLERGAGLRVTMHQPVLLCLLALIWLTVK
130 140 150 160 170
>>NP_001073592 (OMIM: 123400,137440,176640,245300,600072 (253 aa)
initn: 119 init1: 55 opt: 151 Z-score: 205.2 bits: 45.0 E(85289): 0.00011
Smith-Waterman score: 151; 25.9% identity (54.9% similar) in 162 aa overlap (34-175:98-252)
10 20 30 40 50 60
pF1KE6 HLSWWWLATVCMLLFSHLSAVQTRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFIKQ-
.::. . :.: . : .: :: .
NP_001 PHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAA--GAVVGGL
70 80 90 100 110 120
70 80 90 100 110
pF1KE6 -GRKLD-------IDFGAEG-NRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINAT-
: : : ::.. .:::. :. ..:. ..: .: . ... :: :.: :
NP_001 GGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYS-NQNNFVHDCVNITI
130 140 150 160 170 180
120 130 140 150 160
pF1KE6 -----QAANQGE-FQKPDNKLHQQVLWRLVQELCSLKH---CEFWLERGAGLRVTMHQPV
....:: : . : :. . :.:...: .. . . .::... . ::
NP_001 KQHTVTTTTKGENFTETDVKMME----RVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
190 200 210 220 230 240
170
pF1KE6 LLCLLALIWLMVK
.: . ::.:.:
NP_001 ILLISFLIFLIVG
250
>>NP_001073590 (OMIM: 123400,137440,176640,245300,600072 (253 aa)
initn: 119 init1: 55 opt: 151 Z-score: 205.2 bits: 45.0 E(85289): 0.00011
Smith-Waterman score: 151; 25.9% identity (54.9% similar) in 162 aa overlap (34-175:98-252)
10 20 30 40 50 60
pF1KE6 HLSWWWLATVCMLLFSHLSAVQTRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFIKQ-
.::. . :.: . : .: :: .
NP_001 PHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAA--GAVVGGL
70 80 90 100 110 120
70 80 90 100 110
pF1KE6 -GRKLD-------IDFGAEG-NRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINAT-
: : : ::.. .:::. :. ..:. ..: .: . ... :: :.: :
NP_001 GGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYS-NQNNFVHDCVNITI
130 140 150 160 170 180
120 130 140 150 160
pF1KE6 -----QAANQGE-FQKPDNKLHQQVLWRLVQELCSLKH---CEFWLERGAGLRVTMHQPV
....:: : . : :. . :.:...: .. . . .::... . ::
NP_001 KQHTVTTTTKGENFTETDVKMME----RVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
190 200 210 220 230 240
170
pF1KE6 LLCLLALIWLMVK
.: . ::.:.:
NP_001 ILLISFLIFLIVG
250
>>NP_000302 (OMIM: 123400,137440,176640,245300,600072,60 (253 aa)
initn: 119 init1: 55 opt: 151 Z-score: 205.2 bits: 45.0 E(85289): 0.00011
Smith-Waterman score: 151; 25.9% identity (54.9% similar) in 162 aa overlap (34-175:98-252)
10 20 30 40 50 60
pF1KE6 HLSWWWLATVCMLLFSHLSAVQTRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFIKQ-
.::. . :.: . : .: :: .
NP_000 PHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAA--GAVVGGL
70 80 90 100 110 120
70 80 90 100 110
pF1KE6 -GRKLD-------IDFGAEG-NRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINAT-
: : : ::.. .:::. :. ..:. ..: .: . ... :: :.: :
NP_000 GGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYS-NQNNFVHDCVNITI
130 140 150 160 170 180
120 130 140 150 160
pF1KE6 -----QAANQGE-FQKPDNKLHQQVLWRLVQELCSLKH---CEFWLERGAGLRVTMHQPV
....:: : . : :. . :.:...: .. . . .::... . ::
NP_000 KQHTVTTTTKGENFTETDVKMME----RVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
190 200 210 220 230 240
170
pF1KE6 LLCLLALIWLMVK
.: . ::.:.:
NP_000 ILLISFLIFLIVG
250
>>NP_898902 (OMIM: 123400,137440,176640,245300,600072,60 (253 aa)
initn: 119 init1: 55 opt: 151 Z-score: 205.2 bits: 45.0 E(85289): 0.00011
Smith-Waterman score: 151; 25.9% identity (54.9% similar) in 162 aa overlap (34-175:98-252)
10 20 30 40 50 60
pF1KE6 HLSWWWLATVCMLLFSHLSAVQTRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFIKQ-
.::. . :.: . : .: :: .
NP_898 PHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAA--GAVVGGL
70 80 90 100 110 120
70 80 90 100 110
pF1KE6 -GRKLD-------IDFGAEG-NRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINAT-
: : : ::.. .:::. :. ..:. ..: .: . ... :: :.: :
NP_898 GGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYS-NQNNFVHDCVNITI
130 140 150 160 170 180
120 130 140 150 160
pF1KE6 -----QAANQGE-FQKPDNKLHQQVLWRLVQELCSLKH---CEFWLERGAGLRVTMHQPV
....:: : . : :. . :.:...: .. . . .::... . ::
NP_898 KQHTVTTTTKGENFTETDVKMME----RVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
190 200 210 220 230 240
170
pF1KE6 LLCLLALIWLMVK
.: . ::.:.:
NP_898 ILLISFLIFLIVG
250
>>NP_001073591 (OMIM: 123400,137440,176640,245300,600072 (253 aa)
initn: 119 init1: 55 opt: 151 Z-score: 205.2 bits: 45.0 E(85289): 0.00011
Smith-Waterman score: 151; 25.9% identity (54.9% similar) in 162 aa overlap (34-175:98-252)
10 20 30 40 50 60
pF1KE6 HLSWWWLATVCMLLFSHLSAVQTRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFIKQ-
.::. . :.: . : .: :: .
NP_001 PHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAA--GAVVGGL
70 80 90 100 110 120
70 80 90 100 110
pF1KE6 -GRKLD-------IDFGAEG-NRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINAT-
: : : ::.. .:::. :. ..:. ..: .: . ... :: :.: :
NP_001 GGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYS-NQNNFVHDCVNITI
130 140 150 160 170 180
120 130 140 150 160
pF1KE6 -----QAANQGE-FQKPDNKLHQQVLWRLVQELCSLKH---CEFWLERGAGLRVTMHQPV
....:: : . : :. . :.:...: .. . . .::... . ::
NP_001 KQHTVTTTTKGENFTETDVKMME----RVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
190 200 210 220 230 240
170
pF1KE6 LLCLLALIWLMVK
.: . ::.:.:
NP_001 ILLISFLIFLIVG
250
176 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:57:05 2016 done: Tue Nov 8 13:57:05 2016
Total Scan time: 4.060 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]