Result of FASTA (omim) for
pFN21AE6494
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6494, 617 aa
1>>>pF1KE6494 617 - 617 aa - 617 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8152+/-0.00042; mu= 22.3335+/- 0.026
mean_var=74.2980+/-16.812, 0's: 0 Z-trim(110.5): 197 B-trim: 929 in 1/52
Lambda= 0.148794
statistics sampled from 18612 (18840) to 18612 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.221), width: 16
Scan time: 7.550
The best scores are: opt bits E(85289)
NP_660159 (OMIM: 610372) solute carrier family 2, ( 617) 3962 860.6 0
XP_016865800 (OMIM: 610372) PREDICTED: solute carr ( 502) 3061 667.1 4e-191
XP_006715412 (OMIM: 610372) PREDICTED: solute carr ( 538) 3052 665.2 1.6e-190
NP_443117 (OMIM: 611036) proton myo-inositol cotra ( 648) 834 189.2 3.9e-47
XP_011536152 (OMIM: 611036) PREDICTED: proton myo- ( 445) 619 142.9 2.3e-33
XP_011536151 (OMIM: 611036) PREDICTED: proton myo- ( 451) 619 142.9 2.3e-33
XP_011536149 (OMIM: 611036) PREDICTED: proton myo- ( 606) 619 143.0 2.9e-33
XP_016874254 (OMIM: 611036) PREDICTED: proton myo- ( 459) 568 131.9 4.7e-30
XP_016874253 (OMIM: 611036) PREDICTED: proton myo- ( 459) 568 131.9 4.7e-30
XP_011527363 (OMIM: 208050,606145) PREDICTED: solu ( 544) 539 125.8 4e-28
XP_016883576 (OMIM: 208050,606145) PREDICTED: solu ( 473) 536 125.1 5.6e-28
XP_011527367 (OMIM: 208050,606145) PREDICTED: solu ( 494) 536 125.1 5.8e-28
XP_011527366 (OMIM: 208050,606145) PREDICTED: solu ( 507) 536 125.1 5.9e-28
XP_011527365 (OMIM: 208050,606145) PREDICTED: solu ( 532) 536 125.1 6.1e-28
XP_011527364 (OMIM: 208050,606145) PREDICTED: solu ( 533) 536 125.1 6.1e-28
NP_110404 (OMIM: 208050,606145) solute carrier fam ( 541) 536 125.1 6.2e-28
XP_011527362 (OMIM: 208050,606145) PREDICTED: solu ( 562) 536 125.1 6.3e-28
XP_016874255 (OMIM: 611036) PREDICTED: proton myo- ( 408) 451 106.8 1.6e-22
NP_001033 (OMIM: 138190) solute carrier family 2, ( 509) 444 105.3 5.2e-22
XP_011539127 (OMIM: 610371) PREDICTED: solute carr ( 383) 424 100.9 8.3e-21
NP_997303 (OMIM: 610371) solute carrier family 2, ( 512) 424 101.1 1e-20
XP_011539126 (OMIM: 610371) PREDICTED: solute carr ( 517) 424 101.1 1e-20
NP_001315549 (OMIM: 138230) solute carrier family ( 457) 402 96.3 2.5e-19
XP_016857625 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
XP_016857622 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
XP_016857626 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
NP_003030 (OMIM: 138230) solute carrier family 2, ( 501) 402 96.3 2.7e-19
XP_016857623 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
XP_016857624 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
XP_016857630 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
NP_001315548 (OMIM: 138230) solute carrier family ( 501) 402 96.3 2.7e-19
XP_005263548 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
XP_016857629 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
XP_016857627 (OMIM: 138230) PREDICTED: solute carr ( 501) 402 96.3 2.7e-19
XP_016857631 (OMIM: 138230) PREDICTED: solute carr ( 442) 349 84.9 6.5e-16
XP_006714032 (OMIM: 606142,612076) PREDICTED: solu ( 423) 314 77.4 1.1e-13
XP_011512168 (OMIM: 606142,612076) PREDICTED: solu ( 445) 314 77.4 1.2e-13
XP_011512167 (OMIM: 606142,612076) PREDICTED: solu ( 452) 314 77.4 1.2e-13
XP_011512163 (OMIM: 606142,612076) PREDICTED: solu ( 486) 314 77.4 1.3e-13
XP_016863947 (OMIM: 606142,612076) PREDICTED: solu ( 487) 314 77.4 1.3e-13
NP_001001290 (OMIM: 606142,612076) solute carrier ( 511) 314 77.4 1.3e-13
XP_011512162 (OMIM: 606142,612076) PREDICTED: solu ( 537) 314 77.5 1.4e-13
XP_011512161 (OMIM: 606142,612076) PREDICTED: solu ( 538) 314 77.5 1.4e-13
NP_064425 (OMIM: 606142,612076) solute carrier fam ( 540) 314 77.5 1.4e-13
XP_006714031 (OMIM: 606142,612076) PREDICTED: solu ( 563) 314 77.5 1.4e-13
XP_011512160 (OMIM: 606142,612076) PREDICTED: solu ( 586) 314 77.5 1.4e-13
XP_011512159 (OMIM: 606142,612076) PREDICTED: solu ( 586) 314 77.5 1.4e-13
XP_016863946 (OMIM: 606142,612076) PREDICTED: solu ( 609) 314 77.5 1.5e-13
XP_011512158 (OMIM: 606142,612076) PREDICTED: solu ( 615) 314 77.5 1.5e-13
NP_001020109 (OMIM: 610367) solute carrier family ( 496) 307 75.9 3.6e-13
>>NP_660159 (OMIM: 610372) solute carrier family 2, faci (617 aa)
initn: 3962 init1: 3962 opt: 3962 Z-score: 4596.5 bits: 860.6 E(85289): 0
Smith-Waterman score: 3962; 100.0% identity (100.0% similar) in 617 aa overlap (1-617:1-617)
10 20 30 40 50 60
pF1KE6 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 PMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 PMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 SLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 SLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLE
550 560 570 580 590 600
610
pF1KE6 CNKLCGRGQSRQLSPET
:::::::::::::::::
NP_660 CNKLCGRGQSRQLSPET
610
>>XP_016865800 (OMIM: 610372) PREDICTED: solute carrier (502 aa)
initn: 3043 init1: 3043 opt: 3061 Z-score: 3552.3 bits: 667.1 E(85289): 4e-191
Smith-Waterman score: 3061; 96.8% identity (98.0% similar) in 504 aa overlap (1-503:1-500)
10 20 30 40 50 60
pF1KE6 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 PMPWLVLSEIFPGGIR-GRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSL
: . ::: .:. :. .::.
XP_016 PS----IESIFPENIKIGEILALSCF
490 500
>>XP_006715412 (OMIM: 610372) PREDICTED: solute carrier (538 aa)
initn: 3043 init1: 3043 opt: 3052 Z-score: 3541.5 bits: 665.2 E(85289): 1.6e-190
Smith-Waterman score: 3052; 95.3% identity (98.0% similar) in 508 aa overlap (1-506:1-508)
10 20 30 40 50 60
pF1KE6 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 PMPWLVL--SEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMS
: . . : .:.. .: ........
XP_006 PRDVIFIGQSTNLPSAPEGDTISISKTIYYAAYNKAIIQTALERQPRAKTVSAFSHKT
490 500 510 520 530
>>NP_443117 (OMIM: 611036) proton myo-inositol cotranspo (648 aa)
initn: 743 init1: 369 opt: 834 Z-score: 967.3 bits: 189.2 E(85289): 3.9e-47
Smith-Waterman score: 837; 31.2% identity (65.5% similar) in 536 aa overlap (39-560:80-605)
10 20 30 40 50 60
pF1KE6 GPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQI
:... .: .:..:.: ::. :..:::.: .
NP_443 SLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLL
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE6 KTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL
: :.:. ::..::: : .: ...:.::.: .:::.::.:.: :. :: :: .
NP_443 KRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN
110 120 130 140 150 160
130 140 150 160 170 180
pF1KE6 SYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYA
. .:..::...:..:...:... :::::..: . :: ::..: :.:. : . : . . :
NP_443 NKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGA
170 180 190 200 210 220
190 200 210 220 230 240
pF1KE6 FANVFH-GWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTT
:. . . ::.::.::. .:.: ... ::: :::.:..::: : ..:...:. .
NP_443 FSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTID
230 240 250 260 270 280
250 260 270 280 290 300
pF1KE6 EELTVIKSSLKDEYQY--SFWDLF-R--SKDNMRTRIMIGLTLVFFVQITGQPNILFYAS
:: ::.....: . : .. : : : ...: : .: :..: .:..:..
NP_443 EEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSA
290 300 310 320 330 340
310 320 330 340 350 360
pF1KE6 TVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSK--TFLCIGSSVMAASLVT
:.:. : .... : .. .. .. : :. .. ::..:: . :: ......: ...
NP_443 TILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILA
350 360 370 380 390 400
370 380 390 400 410
pF1KE6 MGIV---NLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRS
.:.: ... ...: : : .. . . : :. . : :. . .
NP_443 LGFVLSAQVSPRITFKPIAPSGQNATCT----------RYSYCNECMLDPDCGFCYKMNK
410 420 430 440 450
420 430 440 450 460 470
pF1KE6 SLMPLRNDVDKRGETTSASLLNAGLSHTEYQ---IVTDPGDVPAFLKWLSLASLLVYVAA
: . . : .:. . . ..:... : . :. .: .: .:..:..
NP_443 STVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVF
460 470 480 490 500 510
480 490 500 510 520 530
pF1KE6 FSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIY
:. :.::::: : :::.: :. . : .:..:: .:.:.::::: ... . . :.:
NP_443 FAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLY
520 530 540 550 560 570
540 550 560 570 580 590
pF1KE6 TIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKP
. .. ..:::. .::::: .::.:
NP_443 AGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSNYHL
580 590 600 610 620 630
>>XP_011536152 (OMIM: 611036) PREDICTED: proton myo-inos (445 aa)
initn: 500 init1: 334 opt: 619 Z-score: 719.9 bits: 142.9 E(85289): 2.3e-33
Smith-Waterman score: 619; 33.8% identity (70.7% similar) in 334 aa overlap (39-364:80-413)
10 20 30 40 50 60
pF1KE6 GPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQI
:... .: .:..:.: ::. :..:::.: .
XP_011 SLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLL
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE6 KTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL
: :.:. ::..::: : .: ...:.::.: .:::.::.:.: :. :: :: .
XP_011 KRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN
110 120 130 140 150 160
130 140 150 160 170 180
pF1KE6 SYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYA
. .:..::...:..:...:... :::::..: . :: ::..: :.:. : . : . . :
XP_011 NKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGA
170 180 190 200 210 220
190 200 210 220 230 240
pF1KE6 FANVFH-GWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTT
:. . . ::.::.::. .:.: ... ::: :::.:..::: : ..:...:. .
XP_011 FSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTID
230 240 250 260 270 280
250 260 270 280 290 300
pF1KE6 EELTVIKSSLKDEYQY--SFWDLF-R--SKDNMRTRIMIGLTLVFFVQITGQPNILFYAS
:: ::.....: . : .. : : : ...: : .: :..: .:..:..
XP_011 EEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSA
290 300 310 320 330 340
310 320 330 340 350 360
pF1KE6 TVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSK--TFLCIGSSVMAASLVT
:.:. : .... : .. .. .. : :. .. ::..:: . :: ......: ...
XP_011 TILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILA
350 360 370 380 390 400
370 380 390 400 410 420
pF1KE6 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
.:.:
XP_011 LGFVLSAQVSPRITFKPIAPSGQNATCTRYSLQAPY
410 420 430 440
>>XP_011536151 (OMIM: 611036) PREDICTED: proton myo-inos (451 aa)
initn: 500 init1: 334 opt: 619 Z-score: 719.9 bits: 142.9 E(85289): 2.3e-33
Smith-Waterman score: 619; 33.8% identity (70.7% similar) in 334 aa overlap (39-364:80-413)
10 20 30 40 50 60
pF1KE6 GPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQI
:... .: .:..:.: ::. :..:::.: .
XP_011 SLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLL
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE6 KTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL
: :.:. ::..::: : .: ...:.::.: .:::.::.:.: :. :: :: .
XP_011 KRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN
110 120 130 140 150 160
130 140 150 160 170 180
pF1KE6 SYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYA
. .:..::...:..:...:... :::::..: . :: ::..: :.:. : . : . . :
XP_011 NKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGA
170 180 190 200 210 220
190 200 210 220 230 240
pF1KE6 FANVFH-GWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTT
:. . . ::.::.::. .:.: ... ::: :::.:..::: : ..:...:. .
XP_011 FSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTID
230 240 250 260 270 280
250 260 270 280 290 300
pF1KE6 EELTVIKSSLKDEYQY--SFWDLF-R--SKDNMRTRIMIGLTLVFFVQITGQPNILFYAS
:: ::.....: . : .. : : : ...: : .: :..: .:..:..
XP_011 EEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSA
290 300 310 320 330 340
310 320 330 340 350 360
pF1KE6 TVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSK--TFLCIGSSVMAASLVT
:.:. : .... : .. .. .. : :. .. ::..:: . :: ......: ...
XP_011 TILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILA
350 360 370 380 390 400
370 380 390 400 410 420
pF1KE6 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
.:.:
XP_011 LGFVLSAQVSPRITFKPIAPSGQNATCTRYSGQPHQDSGMLF
410 420 430 440 450
>>XP_011536149 (OMIM: 611036) PREDICTED: proton myo-inos (606 aa)
initn: 708 init1: 334 opt: 619 Z-score: 718.2 bits: 143.0 E(85289): 2.9e-33
Smith-Waterman score: 798; 31.1% identity (63.6% similar) in 528 aa overlap (39-560:80-563)
10 20 30 40 50 60
pF1KE6 GPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQI
:... .: .:..:.: ::. :..:::.: .
XP_011 SLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLL
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE6 KTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL
: :.:. ::..::: : .: ...:.::.: .:::.::.:.: :. :: :: .
XP_011 KRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAAN
110 120 130 140 150 160
130 140 150 160 170 180
pF1KE6 SYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYA
. .:..::...:..:...:... :::::..: . :: ::..: :.:. : . : . . :
XP_011 NKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGA
170 180 190 200 210 220
190 200 210 220 230 240
pF1KE6 FANVFH-GWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTT
:. . . ::.::.::. .:.: ... ::: :::.:..::: : ..:...:. .
XP_011 FSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTID
230 240 250 260 270 280
250 260 270 280 290 300
pF1KE6 EELTVIKSSLKDEYQY--SFWDLF-R--SKDNMRTRIMIGLTLVFFVQITGQPNILFYAS
:: ::.....: . : .. : : : ...: : .: :..: .:..:..
XP_011 EEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSA
290 300 310 320 330 340
310 320 330 340 350 360
pF1KE6 TVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMG
:.:. : .... : .. .. .. : :. .. ::..:: . : .:: .:.. :..
XP_011 TILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRK-LTFGS--LAGTTVALI
350 360 370 380 390 400
370 380 390 400 410 420
pF1KE6 IVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPL
:. :.. .. ... . . : : .: :
XP_011 ILALGF------------VLSAQVSPRITFKPIAPSGQNATCT-----------------
410 420 430
430 440 450 460 470 480
pF1KE6 RNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPM
: ... . . ... : :.. : .: .: .:..:.. :. :.:::
XP_011 RYRCENETKFKTEDIFWA------YNFCPTP------YSWTALLGLILYLVFFAPGMGPM
440 450 460 470 480
490 500 510 520 530 540
pF1KE6 PWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASL
:: : :::.: :. . : .:..:: .:.:.::::: ... . . :.:. .. ..:
XP_011 PWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 LFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLECN
::. .::::: .::.:
XP_011 LFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSNYHLSDNDASDV
550 560 570 580 590 600
>>XP_016874254 (OMIM: 611036) PREDICTED: proton myo-inos (459 aa)
initn: 474 init1: 222 opt: 568 Z-score: 660.6 bits: 131.9 E(85289): 4.7e-30
Smith-Waterman score: 568; 29.1% identity (62.3% similar) in 422 aa overlap (153-560:5-416)
130 140 150 160 170 180
pF1KE6 VLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSA
:::::..: . :: ::..: :.:. : . :
XP_016 MTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFA
10 20 30
190 200 210 220 230 240
pF1KE6 YISNYAFANVFH-GWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLR
. . ::. . . ::.::.::. .:.: ... ::: :::.:..::: : ..:...:
XP_016 SVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMR
40 50 60 70 80 90
250 260 270 280 290
pF1KE6 ALSDTTEELTVIKSSLKDEYQY--SFWDLF-R--SKDNMRTRIMIGLTLVFFVQITGQPN
. . :: ::.....: . : .. : : : ...: : .: :..: .
XP_016 GNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINT
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE6 ILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSK--TFLCIGSSVM
:..:..:.:. : .... : .. .. .. : :. .. ::..:: . :: ......
XP_016 IMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTV
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE6 AASLVTMGIV---NLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGI
: ....:.: ... ...: : : .. . . : :. . : :.
XP_016 ALIILALGFVLSAQVSPRITFKPIAPSGQNATCT----------RYSYCNECMLDPDCGF
220 230 240 250 260
420 430 440 450 460
pF1KE6 SSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQ---IVTDPGDVPAFLKWLSLASL
. .: . . : .:. . . ..:... : . :. .: .: .:
XP_016 CYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGL
270 280 290 300 310 320
470 480 490 500 510 520
pF1KE6 LVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLP
..:.. :. :.::::: : :::.: :. . : .:..:: .:.:.::::: ... .
XP_016 ILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYY
330 340 350 360 370 380
530 540 550 560 570 580
pF1KE6 WVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQ
. :.:. .. ..:::. .::::: .::.:
XP_016 GAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVK
390 400 410 420 430 440
590 600 610
pF1KE6 PQKRKPQEQLLECNKLCGRGQSRQLSPET
XP_016 GSNYHLSDNDASDVE
450
>>XP_016874253 (OMIM: 611036) PREDICTED: proton myo-inos (459 aa)
initn: 474 init1: 222 opt: 568 Z-score: 660.6 bits: 131.9 E(85289): 4.7e-30
Smith-Waterman score: 568; 29.1% identity (62.3% similar) in 422 aa overlap (153-560:5-416)
130 140 150 160 170 180
pF1KE6 VLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSA
:::::..: . :: ::..: :.:. : . :
XP_016 MTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFA
10 20 30
190 200 210 220 230 240
pF1KE6 YISNYAFANVFH-GWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLR
. . ::. . . ::.::.::. .:.: ... ::: :::.:..::: : ..:...:
XP_016 SVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMR
40 50 60 70 80 90
250 260 270 280 290
pF1KE6 ALSDTTEELTVIKSSLKDEYQY--SFWDLF-R--SKDNMRTRIMIGLTLVFFVQITGQPN
. . :: ::.....: . : .. : : : ...: : .: :..: .
XP_016 GNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINT
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE6 ILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSK--TFLCIGSSVM
:..:..:.:. : .... : .. .. .. : :. .. ::..:: . :: ......
XP_016 IMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTV
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE6 AASLVTMGIV---NLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGI
: ....:.: ... ...: : : .. . . : :. . : :.
XP_016 ALIILALGFVLSAQVSPRITFKPIAPSGQNATCT----------RYSYCNECMLDPDCGF
220 230 240 250 260
420 430 440 450 460
pF1KE6 SSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQ---IVTDPGDVPAFLKWLSLASL
. .: . . : .:. . . ..:... : . :. .: .: .:
XP_016 CYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGL
270 280 290 300 310 320
470 480 490 500 510 520
pF1KE6 LVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLP
..:.. :. :.::::: : :::.: :. . : .:..:: .:.:.::::: ... .
XP_016 ILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYY
330 340 350 360 370 380
530 540 550 560 570 580
pF1KE6 WVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQ
. :.:. .. ..:::. .::::: .::.:
XP_016 GAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVK
390 400 410 420 430 440
590 600 610
pF1KE6 PQKRKPQEQLLECNKLCGRGQSRQLSPET
XP_016 GSNYHLSDNDASDVE
450
>>XP_011527363 (OMIM: 208050,606145) PREDICTED: solute c (544 aa)
initn: 1197 init1: 536 opt: 539 Z-score: 626.0 bits: 125.8 E(85289): 4e-28
Smith-Waterman score: 1191; 40.7% identity (67.8% similar) in 543 aa overlap (27-566:5-517)
10 20 30 40 50 60
pF1KE6 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI
:. :: :. ..:. :: ::::..
XP_011 MKAYSHSPPVLPLCASVSLLG-------GLTFGYELAV
10 20 30
70 80 90 100 110 120
pF1KE6 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG
:::::: .. ..::: :::..:.::..:::::::.:: ::: :::. ::. :. .: :
XP_011 ISGALLPLQLDFGLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL
::.: :. : . :..:: ..: .:::::.: :.:..:.. ..::.:::: : :..:::
XP_011 SLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGIL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL
.: :::.:.. ::..::: . .:::.... ::: . .: :. : : :
XP_011 LSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFLPAGT-------DETATHKDLIPL
160 170 180 190 200
250 260 270 280 290 300
pF1KE6 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY
.. . .: . .::: ::::..:::: : .:: ::.: :.:::::.: :
XP_011 QG--GEAPKLGPGRP------RYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCY
210 220 230 240 250
310 320 330 340 350 360
pF1KE6 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT
:::...::::... .: :::.:.:.::: .:. : :::..: ...: : ..:: :.
XP_011 ASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSG
260 270 280 290 300 310
370 380 390 400 410
pF1KE6 MGIVNLNIHMNFTHICRS-HNSINQSL--DESVIYGPGNLSTNNNTLRDHFKGISSHSRS
.:.:.. . :. : . :. .:. .: . ..: : .:. . : : ...
XP_011 IGLVSFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQREPILSTAKK
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE6 SLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSI
. : . : . : :...: :. :.:.: .: :.:.:.:::.
XP_011 T-KPHPRSGDPSAPPRLA--LSSALPGPPL-----PARGHALLRWTALLCLMVFVSAFSF
380 390 400 410 420
480 490 500 510 520 530
pF1KE6 GLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIM
:.::. :::::::.: :::::.:. .:.::. ::.:::.:: . ::: :. ..: .
XP_011 GFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLT
430 440 450 460 470 480
540 550 560 570 580 590
pF1KE6 SLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQ
.. .: :. .:.::::: :: .:.... :
XP_011 AVLGLGFIYLFVPETKGQSLAEIDQQFQKRRFTLSFGHRQNSTGIPYSRIEISAAS
490 500 510 520 530 540
617 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:51:35 2016 done: Tue Nov 8 13:51:36 2016
Total Scan time: 7.550 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]