Result of FASTA (omim) for
pFN21AE6467
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6467, 515 aa
1>>>pF1KE6467 515 - 515 aa - 515 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9434+/-0.000397; mu= 19.8644+/- 0.025
mean_var=60.7523+/-12.992, 0's: 0 Z-trim(111.3): 25 B-trim: 1285 in 1/54
Lambda= 0.164548
statistics sampled from 19786 (19803) to 19786 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.588), E-opt: 0.2 (0.232), width: 16
Scan time: 5.950
The best scores are: opt bits E(85289)
NP_631912 (OMIM: 611527) sodium/hydrogen exchanger ( 515) 3346 803.2 0
XP_006714156 (OMIM: 611527) PREDICTED: sodium/hydr ( 515) 3337 801.1 0
XP_011529925 (OMIM: 611527) PREDICTED: sodium/hydr ( 515) 3337 801.1 0
XP_011529924 (OMIM: 611527) PREDICTED: sodium/hydr ( 515) 3337 801.1 0
NP_001094344 (OMIM: 611527) sodium/hydrogen exchan ( 475) 2893 695.7 8e-200
XP_006714148 (OMIM: 611789) PREDICTED: mitochondri ( 537) 1887 456.9 6.9e-128
NP_849155 (OMIM: 611789) mitochondrial sodium/hydr ( 537) 1887 456.9 6.9e-128
NP_001287683 (OMIM: 611789) mitochondrial sodium/h ( 480) 1570 381.6 2.8e-105
XP_006714149 (OMIM: 611789) PREDICTED: mitochondri ( 480) 1570 381.6 2.8e-105
NP_001287685 (OMIM: 611789) mitochondrial sodium/h ( 417) 1171 286.8 8.2e-77
>>NP_631912 (OMIM: 611527) sodium/hydrogen exchanger 9B1 (515 aa)
initn: 3346 init1: 3346 opt: 3346 Z-score: 4289.1 bits: 803.2 E(85289): 0
Smith-Waterman score: 3346; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515)
10 20 30 40 50 60
pF1KE6 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
430 440 450 460 470 480
490 500 510
pF1KE6 APNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
:::::::::::::::::::::::::::::::::::
NP_631 APNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
490 500 510
>>XP_006714156 (OMIM: 611527) PREDICTED: sodium/hydrogen (515 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 4277.6 bits: 801.1 E(85289): 0
Smith-Waterman score: 3337; 99.8% identity (100.0% similar) in 515 aa overlap (1-515:1-515)
10 20 30 40 50 60
pF1KE6 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPL
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_006 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAQEETKTVLSDTEEIKPQTKKETYISCPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
430 440 450 460 470 480
490 500 510
pF1KE6 APNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
:::::::::::::::::::::::::::::::::::
XP_006 APNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
490 500 510
>>XP_011529925 (OMIM: 611527) PREDICTED: sodium/hydrogen (515 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 4277.6 bits: 801.1 E(85289): 0
Smith-Waterman score: 3337; 99.8% identity (100.0% similar) in 515 aa overlap (1-515:1-515)
10 20 30 40 50 60
pF1KE6 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPL
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_011 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAQEETKTVLSDTEEIKPQTKKETYISCPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
430 440 450 460 470 480
490 500 510
pF1KE6 APNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
:::::::::::::::::::::::::::::::::::
XP_011 APNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
490 500 510
>>XP_011529924 (OMIM: 611527) PREDICTED: sodium/hydrogen (515 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 4277.6 bits: 801.1 E(85289): 0
Smith-Waterman score: 3337; 99.8% identity (100.0% similar) in 515 aa overlap (1-515:1-515)
10 20 30 40 50 60
pF1KE6 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPL
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_011 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAQEETKTVLSDTEEIKPQTKKETYISCPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
430 440 450 460 470 480
490 500 510
pF1KE6 APNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
:::::::::::::::::::::::::::::::::::
XP_011 APNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
490 500 510
>>NP_001094344 (OMIM: 611527) sodium/hydrogen exchanger (475 aa)
initn: 2893 init1: 2893 opt: 2893 Z-score: 3708.5 bits: 695.7 E(85289): 8e-200
Smith-Waterman score: 2893; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KE6 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 CFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILIT
::::::::::::::::::::::::
NP_001 CFAGFSFKEKIFIALAWMPKATVQINQAILLLFLLREEWTNCKVAKKCEYTKERQ
430 440 450 460 470
>>XP_006714148 (OMIM: 611789) PREDICTED: mitochondrial s (537 aa)
initn: 1883 init1: 1737 opt: 1887 Z-score: 2417.0 bits: 456.9 E(85289): 6.9e-128
Smith-Waterman score: 1887; 59.4% identity (86.0% similar) in 465 aa overlap (35-498:56-519)
10 20 30 40 50 60
pF1KE6 ESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPLRGVL
: : . :: . : .. ...:: .:.:
XP_006 HQEAQEETVMKLKGIDANEPTEGSILLKSSEKKLQETPTEANHVQRLRQ-MLACPPHGLL
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE6 NVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLVPPLP
. .::: .:. ..: ..::: ::: ::::::::..:.:: ::::::.: ::..: .::::
XP_006 DRVITNVTIIVLLWAVVWSITGSECLPGGNLFGIIILFYCAIIGGKLLGLIKLPTLPPLP
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE6 PLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHLKVVC
::::::::: :::.: ::..:.. . ::: ::::::.:::.::::::: .::..:: ::
XP_006 SLLGMLLAGFLIRNIPVINDNVQIKHKWSSSLRSIALSIILVRAGLGLDSKALKKLKGVC
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE6 FRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENGYGVE
::..:::..:: ..:...:... .::::.:.::::::::::::::: :..:: .:::::
XP_006 VRLSMGPCIVEACTSALLAHYLLGLPWQWGFILGFVLGAVSPAVVVPSMLLLQGGGYGVE
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE6 EGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVLGFFV
.:.:::::::.:.:::::::::::::.:.::.:. . :.. .. .: :.. .: :::::.
XP_006 KGVPTLLMAAGSFDDILAITGFNTCLGIAFSTGSTVFNVLRGVLEVVIGVATGSVLGFFI
270 280 290 300 310 320
310 320 330 340 350 360
pF1KE6 RYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQEKMK
.::::.:: ::. :: :::: . : ::..: ..:. :::::::::..:.:: :..:: .
XP_006 QYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHFGFPGSGGLCTLVMAFLAGMGWTSEKAE
330 340 350 360 370 380
370 380 390 400 410 420
pF1KE6 VQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLMCFAG
:.:::...:::::::::::.:::::..::. . ::. :::...:. .:::::.:..::::
XP_006 VEKIIAVAWDIFQPLLFGLIGAEVSIASLRPETVGLCVATVGIAVLIRILTTFLMVCFAG
390 400 410 420 430 440
430 440 450 460 470 480
pF1KE6 FSFKEKIFIALAWMPKATVQAVLGPLALETARVSAP-HLEPYAKDVMTVAFLAILITAPN
:..::::::..::.:::::::..: .::.::: . .:: :. ::.:::::.::::::
XP_006 FNLKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEDYGMDVLTVAFLSILITAPI
450 460 470 480 490 500
490 500 510
pF1KE6 GALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
:.::.:.:::..: .
XP_006 GSLLIGLLGPRLLQKVEHQNKDEEVQGETSVQV
510 520 530
>>NP_849155 (OMIM: 611789) mitochondrial sodium/hydrogen (537 aa)
initn: 1883 init1: 1737 opt: 1887 Z-score: 2417.0 bits: 456.9 E(85289): 6.9e-128
Smith-Waterman score: 1887; 59.4% identity (86.0% similar) in 465 aa overlap (35-498:56-519)
10 20 30 40 50 60
pF1KE6 ESKNEHLEDENFQTSTTPQSLIDPNNTAHEETKTVLSDTEEIKPQTKKETYISCPLRGVL
: : . :: . : .. ...:: .:.:
NP_849 HQEAQEETVMKLKGIDANEPTEGSILLKSSEKKLQETPTEANHVQRLRQ-MLACPPHGLL
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE6 NVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLVPPLP
. .::: .:. ..: ..::: ::: ::::::::..:.:: ::::::.: ::..: .::::
NP_849 DRVITNVTIIVLLWAVVWSITGSECLPGGNLFGIIILFYCAIIGGKLLGLIKLPTLPPLP
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE6 PLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHLKVVC
::::::::: :::.: ::..:.. . ::: ::::::.:::.::::::: .::..:: ::
NP_849 SLLGMLLAGFLIRNIPVINDNVQIKHKWSSSLRSIALSIILVRAGLGLDSKALKKLKGVC
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE6 FRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENGYGVE
::..:::..:: ..:...:... .::::.:.::::::::::::::: :..:: .:::::
NP_849 VRLSMGPCIVEACTSALLAHYLLGLPWQWGFILGFVLGAVSPAVVVPSMLLLQGGGYGVE
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE6 EGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVLGFFV
.:.:::::::.:.:::::::::::::.:.::.:. . :.. .. .: :.. .: :::::.
NP_849 KGVPTLLMAAGSFDDILAITGFNTCLGIAFSTGSTVFNVLRGVLEVVIGVATGSVLGFFI
270 280 290 300 310 320
310 320 330 340 350 360
pF1KE6 RYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQEKMK
.::::.:: ::. :: :::: . : ::..: ..:. :::::::::..:.:: :..:: .
NP_849 QYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHFGFPGSGGLCTLVMAFLAGMGWTSEKAE
330 340 350 360 370 380
370 380 390 400 410 420
pF1KE6 VQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLMCFAG
:.:::...:::::::::::.:::::..::. . ::. :::...:. .:::::.:..::::
NP_849 VEKIIAVAWDIFQPLLFGLIGAEVSIASLRPETVGLCVATVGIAVLIRILTTFLMVCFAG
390 400 410 420 430 440
430 440 450 460 470 480
pF1KE6 FSFKEKIFIALAWMPKATVQAVLGPLALETARVSAP-HLEPYAKDVMTVAFLAILITAPN
:..::::::..::.:::::::..: .::.::: . .:: :. ::.:::::.::::::
NP_849 FNLKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEDYGMDVLTVAFLSILITAPI
450 460 470 480 490 500
490 500 510
pF1KE6 GALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
:.::.:.:::..: .
NP_849 GSLLIGLLGPRLLQKVEHQNKDEEVQGETSVQV
510 520 530
>>NP_001287683 (OMIM: 611789) mitochondrial sodium/hydro (480 aa)
initn: 1571 init1: 1425 opt: 1570 Z-score: 2011.0 bits: 381.6 E(85289): 2.8e-105
Smith-Waterman score: 1570; 61.6% identity (88.4% similar) in 372 aa overlap (128-498:91-462)
100 110 120 130 140 150
pF1KE6 LFIIFYSAIIGGKILQLIRIPLVPPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILR
::::::: :::.: ::..:.. . ::: ::
NP_001 ETPTEANHVQRLRQMLACPPHGLLDRVITNGMLLAGFLIRNIPVINDNVQIKHKWSSSLR
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE6 SIALTIILIRAGLGLDPQALRHLKVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLL
::::.:::.::::::: .::..:: :: ::..:::..:: ..:...:... .::::.:.:
NP_001 SIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTSALLAHYLLGLPWQWGFIL
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE6 GFVLGAVSPAVVVPYMMVLQENGYGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSG
:::::::::::::: :..:: .:::::.:.:::::::.:.:::::::::::::.:.::.:
NP_001 GFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDDILAITGFNTCLGIAFSTG
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE6 GILNNAIASIRNVCISLLAGIVLGFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRI
. . :.. .. .: :.. .: :::::..::::.:: ::. :: :::: . : ::..: ..
NP_001 STVFNVLRGVLEVVIGVATGSVLGFFIQYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHF
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE6 GLHGSGGLCTLVLSFIAGTKWSQEKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNI
:. :::::::::..:.:: :..:: .:.:::...:::::::::::.:::::..::. .
NP_001 GFPGSGGLCTLVMAFLAGMGWTSEKAEVEKIIAVAWDIFQPLLFGLIGAEVSIASLRPET
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE6 VGISVATLSLALCVRILTTYLLMCFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARV
::. :::...:. .:::::.:..:::::..::::::..::.:::::::..: .::.:::
NP_001 VGLCVATVGIAVLIRILTTFLMVCFAGFNLKEKIFISFAWLPKATVQAAIGSVALDTARS
370 380 390 400 410 420
460 470 480 490 500 510
pF1KE6 SAP-HLEPYAKDVMTVAFLAILITAPNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
. .:: :. ::.:::::.:::::: :.::.:.:::..: .
NP_001 HGEKQLEDYGMDVLTVAFLSILITAPIGSLLIGLLGPRLLQKVEHQNKDEEVQGETSVQV
430 440 450 460 470 480
>>XP_006714149 (OMIM: 611789) PREDICTED: mitochondrial s (480 aa)
initn: 1571 init1: 1425 opt: 1570 Z-score: 2011.0 bits: 381.6 E(85289): 2.8e-105
Smith-Waterman score: 1570; 61.6% identity (88.4% similar) in 372 aa overlap (128-498:91-462)
100 110 120 130 140 150
pF1KE6 LFIIFYSAIIGGKILQLIRIPLVPPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILR
::::::: :::.: ::..:.. . ::: ::
XP_006 ETPTEANHVQRLRQMLACPPHGLLDRVITNGMLLAGFLIRNIPVINDNVQIKHKWSSSLR
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE6 SIALTIILIRAGLGLDPQALRHLKVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLL
::::.:::.::::::: .::..:: :: ::..:::..:: ..:...:... .::::.:.:
XP_006 SIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTSALLAHYLLGLPWQWGFIL
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE6 GFVLGAVSPAVVVPYMMVLQENGYGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSG
:::::::::::::: :..:: .:::::.:.:::::::.:.:::::::::::::.:.::.:
XP_006 GFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDDILAITGFNTCLGIAFSTG
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE6 GILNNAIASIRNVCISLLAGIVLGFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRI
. . :.. .. .: :.. .: :::::..::::.:: ::. :: :::: . : ::..: ..
XP_006 STVFNVLRGVLEVVIGVATGSVLGFFIQYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHF
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE6 GLHGSGGLCTLVLSFIAGTKWSQEKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNI
:. :::::::::..:.:: :..:: .:.:::...:::::::::::.:::::..::. .
XP_006 GFPGSGGLCTLVMAFLAGMGWTSEKAEVEKIIAVAWDIFQPLLFGLIGAEVSIASLRPET
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE6 VGISVATLSLALCVRILTTYLLMCFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARV
::. :::...:. .:::::.:..:::::..::::::..::.:::::::..: .::.:::
XP_006 VGLCVATVGIAVLIRILTTFLMVCFAGFNLKEKIFISFAWLPKATVQAAIGSVALDTARS
370 380 390 400 410 420
460 470 480 490 500 510
pF1KE6 SAP-HLEPYAKDVMTVAFLAILITAPNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
. .:: :. ::.:::::.:::::: :.::.:.:::..: .
XP_006 HGEKQLEDYGMDVLTVAFLSILITAPIGSLLIGLLGPRLLQKVEHQNKDEEVQGETSVQV
430 440 450 460 470 480
>>NP_001287685 (OMIM: 611789) mitochondrial sodium/hydro (417 aa)
initn: 1171 init1: 1171 opt: 1171 Z-score: 1500.0 bits: 286.8 E(85289): 8.2e-77
Smith-Waterman score: 1171; 62.1% identity (88.2% similar) in 272 aa overlap (128-399:91-362)
100 110 120 130 140 150
pF1KE6 LFIIFYSAIIGGKILQLIRIPLVPPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILR
::::::: :::.: ::..:.. . ::: ::
NP_001 ETPTEANHVQRLRQMLACPPHGLLDRVITNGMLLAGFLIRNIPVINDNVQIKHKWSSSLR
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE6 SIALTIILIRAGLGLDPQALRHLKVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLL
::::.:::.::::::: .::..:: :: ::..:::..:: ..:...:... .::::.:.:
NP_001 SIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTSALLAHYLLGLPWQWGFIL
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE6 GFVLGAVSPAVVVPYMMVLQENGYGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSG
:::::::::::::: :..:: .:::::.:.:::::::.:.:::::::::::::.:.::.:
NP_001 GFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDDILAITGFNTCLGIAFSTG
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE6 GILNNAIASIRNVCISLLAGIVLGFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRI
. . :.. .. .: :.. .: :::::..::::.:: ::. :: :::: . : ::..: ..
NP_001 STVFNVLRGVLEVVIGVATGSVLGFFIQYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHF
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE6 GLHGSGGLCTLVLSFIAGTKWSQEKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNI
:. :::::::::..:.:: :..:: .:.:::...:::::::::::.:::::..::. .
NP_001 GFPGSGGLCTLVMAFLAGMGWTSEKAEVEKIIAVAWDIFQPLLFGLIGAEVSIASLRPET
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE6 VGISVATLSLALCVRILTTYLLMCFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARV
::
NP_001 VGCNRICGFGHSKVTWRETIRRLWNGCVDSGIFVHPHHSPNWKSAYWFTGPQASAES
370 380 390 400 410
515 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:34:55 2016 done: Tue Nov 8 13:34:56 2016
Total Scan time: 5.950 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]