Result of FASTA (omim) for
pFN21AE6460
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6460, 469 aa
1>>>pF1KE6460 469 - 469 aa - 469 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8790+/-0.000385; mu= 20.3187+/- 0.024
mean_var=66.8765+/-13.523, 0's: 0 Z-trim(113.0): 59 B-trim: 0 in 0/49
Lambda= 0.156833
statistics sampled from 22115 (22171) to 22115 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.26), width: 16
Scan time: 7.400
The best scores are: opt bits E(85289)
XP_011527450 (OMIM: 211500,211530,613350) PREDICTE ( 469) 3130 717.3 2.2e-206
NP_212134 (OMIM: 211500,211530,613350) solute carr ( 469) 3130 717.3 2.2e-206
XP_005260712 (OMIM: 211500,211530,613350) PREDICTE ( 469) 3130 717.3 2.2e-206
XP_011515602 (OMIM: 607882,614707) PREDICTED: solu ( 357) 544 132.1 2.4e-30
XP_016869309 (OMIM: 607882,614707) PREDICTED: solu ( 445) 544 132.2 2.8e-30
XP_006716722 (OMIM: 607882,614707) PREDICTED: solu ( 445) 544 132.2 2.8e-30
XP_006716723 (OMIM: 607882,614707) PREDICTED: solu ( 445) 544 132.2 2.8e-30
NP_078807 (OMIM: 607882,614707) solute carrier fam ( 445) 544 132.2 2.8e-30
NP_001240745 (OMIM: 607882,614707) solute carrier ( 445) 544 132.2 2.8e-30
XP_016869308 (OMIM: 607882,614707) PREDICTED: solu ( 445) 544 132.2 2.8e-30
XP_006716721 (OMIM: 607882,614707) PREDICTED: solu ( 445) 544 132.2 2.8e-30
NP_001240744 (OMIM: 607882,614707) solute carrier ( 445) 544 132.2 2.8e-30
XP_011522253 (OMIM: 607883,615026) PREDICTED: solu ( 448) 530 129.0 2.6e-29
NP_001098047 (OMIM: 607883,615026) solute carrier ( 448) 530 129.0 2.6e-29
NP_060456 (OMIM: 607883,615026) solute carrier fam ( 448) 530 129.0 2.6e-29
XP_016869310 (OMIM: 607882,614707) PREDICTED: solu ( 281) 523 127.3 5.4e-29
XP_016869311 (OMIM: 607882,614707) PREDICTED: solu ( 281) 523 127.3 5.4e-29
>>XP_011527450 (OMIM: 211500,211530,613350) PREDICTED: s (469 aa)
initn: 3130 init1: 3130 opt: 3130 Z-score: 3826.4 bits: 717.3 E(85289): 2.2e-206
Smith-Waterman score: 3130; 99.4% identity (99.6% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANIGPLLVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANIGPLLVTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LHHFRPSCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLVLTFFLALVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHHFRPSCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLVLTFFLALVDC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTEISDSVPSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTEISDSVPSPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMMACCLVAFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMMACCLVAFFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LQRQPRCWEASVEDLLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYLEEKAAPCCPAHL
:::::::::::::::::::::::::: :::::::::: ::::::::::::::::::::::
XP_011 LQRQPRCWEASVEDLLNDQVTLHSIRPREENDLGPAGTVDSSQGQGYLEEKAAPCCPAHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVANPLASLVSMFLPNRSL
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFIYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVANPLASLVSMFLPNRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVV
370 380 390 400 410 420
430 440 450 460
pF1KE6 LRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNLHCPA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNLHCPA
430 440 450 460
>>NP_212134 (OMIM: 211500,211530,613350) solute carrier (469 aa)
initn: 3130 init1: 3130 opt: 3130 Z-score: 3826.4 bits: 717.3 E(85289): 2.2e-206
Smith-Waterman score: 3130; 99.4% identity (99.6% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANIGPLLVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_212 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANIGPLLVTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LHHFRPSCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLVLTFFLALVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_212 LHHFRPSCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLVLTFFLALVDC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTEISDSVPSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_212 TSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTEISDSVPSPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMMACCLVAFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_212 PTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMMACCLVAFFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LQRQPRCWEASVEDLLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYLEEKAAPCCPAHL
:::::::::::::::::::::::::: :::::::::: ::::::::::::::::::::::
NP_212 LQRQPRCWEASVEDLLNDQVTLHSIRPREENDLGPAGTVDSSQGQGYLEEKAAPCCPAHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVANPLASLVSMFLPNRSL
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_212 AFIYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVANPLASLVSMFLPNRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_212 LFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVV
370 380 390 400 410 420
430 440 450 460
pF1KE6 LRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNLHCPA
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_212 LRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNLHCPA
430 440 450 460
>>XP_005260712 (OMIM: 211500,211530,613350) PREDICTED: s (469 aa)
initn: 3130 init1: 3130 opt: 3130 Z-score: 3826.4 bits: 717.3 E(85289): 2.2e-206
Smith-Waterman score: 3130; 99.4% identity (99.6% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANIGPLLVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANIGPLLVTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LHHFRPSCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLVLTFFLALVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHHFRPSCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLVLTFFLALVDC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTEISDSVPSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTEISDSVPSPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMMACCLVAFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMMACCLVAFFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LQRQPRCWEASVEDLLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYLEEKAAPCCPAHL
:::::::::::::::::::::::::: :::::::::: ::::::::::::::::::::::
XP_005 LQRQPRCWEASVEDLLNDQVTLHSIRPREENDLGPAGTVDSSQGQGYLEEKAAPCCPAHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVANPLASLVSMFLPNRSL
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFIYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVANPLASLVSMFLPNRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVLFSGCLSYVKVMLGVV
370 380 390 400 410 420
430 440 450 460
pF1KE6 LRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNLHCPA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNLHCPA
430 440 450 460
>>XP_011515602 (OMIM: 607882,614707) PREDICTED: solute c (357 aa)
initn: 796 init1: 511 opt: 544 Z-score: 665.8 bits: 132.1 E(85289): 2.4e-30
Smith-Waterman score: 761; 41.0% identity (62.3% similar) in 393 aa overlap (81-467:2-355)
60 70 80 90 100 110
pF1KE6 ANIGPLLVTLLHHFRPSCLSEVPIIFTLLGVGTVTCIIFAFLWNMTSWVLDGHHSIAFLV
:::. ..: ::. .. : ::.:::.
XP_011 MVGTA---LLASLWHHVAPVAGQLHSVAFLA
10 20
120 130 140 150 160 170
pF1KE6 LTFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVT
:.: :::. :.:.::::::.:.:: .: .::.:.:::.::: ..::.:: : :
XP_011 LAFVLALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVGRLEC----
30 40 50 60 70 80
180 190 200 210 220 230
pF1KE6 EISDSVPSPVPTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIM
: :.: ... :: ::. :: :. :: .:: :. .
XP_011 ------P-PAP--------------INGTPG--PPLDFLE-RF-PAS----TFFWALTAL
90 100 110
240 250 260 270 280
pF1KE6 MACCLVAF--FVLQRQPRCWEASVED-LLNDQVTLHSIRLREENDLGPAGMVDSSQGQGY
.. .:: ..: : :: :.. . . . .:: . . . ::. :
XP_011 LVASAAAFQGLLLLLPP---PPSVPTGELGSGLQVGAPGAEEEVEESSPLQEPPSQAAGT
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE6 L---EEKAAPCCPAHLAFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVA
. :: :. : . :.: .::::::.::.::..::: :: .:::::..:. .:
XP_011 TPGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSAA
180 190 200 210 220 230
350 360 370 380 390 400
pF1KE6 NPLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWV
:::: ...: . ::: :: ::.::. ::: ::.::.:::: : : .: ::.: :::
XP_011 NPLACFLAMGVLCRSLAGLGGLSLLGVFCGGYLMALAVLSPCPPLVGTSAGVVLVVLSWV
240 250 260 270 280 290
410 420 430 440 450 460
pF1KE6 LFSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCN
: : .::::: . .:. .: ::: :.:.:.::::::. ::: ... ..: : :
XP_011 LCLGVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCA
300 310 320 330 340 350
pF1KE6 LHCPA
:
XP_011 DPCDS
>>XP_016869309 (OMIM: 607882,614707) PREDICTED: solute c (445 aa)
initn: 1085 init1: 511 opt: 544 Z-score: 664.5 bits: 132.2 E(85289): 2.8e-30
Smith-Waterman score: 1048; 43.2% identity (65.5% similar) in 472 aa overlap (4-467:11-443)
10 20 30 40 50
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANI
: :::: .::::::...::.:::::..: :::::: ::::..:.. :.:.
XP_016 MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYVSVLVALGNL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 GPLLVTLLHHFRPSCLSEVPI-IFTLLG-VGTVTCIIFAFLWNMTSWVLDGHHSIAFLVL
: :.::: ... :. .::: . .:: :::. ..: ::. .. : ::.:::.:
XP_016 GLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTA---LLASLWHHVAPVAGQLHSVAFLAL
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTE
.: :::. :.:.::::::.:.:: .: .::.:.:::.::: ..::.:: : :
XP_016 AFVLALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVGRLEC-----
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ISDSVPSPVPTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMM
: :.: ... :: ::. :: :. :: .:: :. ..
XP_016 -----P-PAP--------------INGTPG--PPLDFLE-RF-PAS----TFFWALTALL
180 190 200
240 250 260 270 280
pF1KE6 ACCLVAF--FVLQRQPRCWEASVED-LLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYL
. .:: ..: : :: :.. . . . .:: . . . ::. :
XP_016 VASAAAFQGLLLLLPP---PPSVPTGELGSGLQVGAPGAEEEVEESSPLQEPPSQAAGTT
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE6 ---EEKAAPCCPAHLAFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVAN
. :: :. : . :.: .::::::.::.::..::: :: .:::::..:. .::
XP_016 PGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSAAN
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE6 PLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVL
::: ...: . ::: :: ::.::. ::: ::.::.:::: : : .: ::.: ::::
XP_016 PLACFLAMGVLCRSLAGLGGLSLLGVFCGGYLMALAVLSPCPPLVGTSAGVVLVVLSWVL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE6 FSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNL
: .::::: . .:. .: ::: :.:.:.::::::. ::: ... ..: : :
XP_016 CLGVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCAD
390 400 410 420 430 440
pF1KE6 HCPA
:
XP_016 PCDS
>>XP_006716722 (OMIM: 607882,614707) PREDICTED: solute c (445 aa)
initn: 1085 init1: 511 opt: 544 Z-score: 664.5 bits: 132.2 E(85289): 2.8e-30
Smith-Waterman score: 1048; 43.2% identity (65.5% similar) in 472 aa overlap (4-467:11-443)
10 20 30 40 50
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANI
: :::: .::::::...::.:::::..: :::::: ::::..:.. :.:.
XP_006 MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYVSVLVALGNL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 GPLLVTLLHHFRPSCLSEVPI-IFTLLG-VGTVTCIIFAFLWNMTSWVLDGHHSIAFLVL
: :.::: ... :. .::: . .:: :::. ..: ::. .. : ::.:::.:
XP_006 GLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTA---LLASLWHHVAPVAGQLHSVAFLAL
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTE
.: :::. :.:.::::::.:.:: .: .::.:.:::.::: ..::.:: : :
XP_006 AFVLALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVGRLEC-----
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ISDSVPSPVPTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMM
: :.: ... :: ::. :: :. :: .:: :. ..
XP_006 -----P-PAP--------------INGTPG--PPLDFLE-RF-PAS----TFFWALTALL
180 190 200
240 250 260 270 280
pF1KE6 ACCLVAF--FVLQRQPRCWEASVED-LLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYL
. .:: ..: : :: :.. . . . .:: . . . ::. :
XP_006 VASAAAFQGLLLLLPP---PPSVPTGELGSGLQVGAPGAEEEVEESSPLQEPPSQAAGTT
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE6 ---EEKAAPCCPAHLAFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVAN
. :: :. : . :.: .::::::.::.::..::: :: .:::::..:. .::
XP_006 PGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSAAN
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE6 PLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVL
::: ...: . ::: :: ::.::. ::: ::.::.:::: : : .: ::.: ::::
XP_006 PLACFLAMGVLCRSLAGLGGLSLLGVFCGGYLMALAVLSPCPPLVGTSAGVVLVVLSWVL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE6 FSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNL
: .::::: . .:. .: ::: :.:.:.::::::. ::: ... ..: : :
XP_006 CLGVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCAD
390 400 410 420 430 440
pF1KE6 HCPA
:
XP_006 PCDS
>>XP_006716723 (OMIM: 607882,614707) PREDICTED: solute c (445 aa)
initn: 1085 init1: 511 opt: 544 Z-score: 664.5 bits: 132.2 E(85289): 2.8e-30
Smith-Waterman score: 1048; 43.2% identity (65.5% similar) in 472 aa overlap (4-467:11-443)
10 20 30 40 50
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANI
: :::: .::::::...::.:::::..: :::::: ::::..:.. :.:.
XP_006 MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYVSVLVALGNL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 GPLLVTLLHHFRPSCLSEVPI-IFTLLG-VGTVTCIIFAFLWNMTSWVLDGHHSIAFLVL
: :.::: ... :. .::: . .:: :::. ..: ::. .. : ::.:::.:
XP_006 GLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTA---LLASLWHHVAPVAGQLHSVAFLAL
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTE
.: :::. :.:.::::::.:.:: .: .::.:.:::.::: ..::.:: : :
XP_006 AFVLALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVGRLEC-----
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ISDSVPSPVPTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMM
: :.: ... :: ::. :: :. :: .:: :. ..
XP_006 -----P-PAP--------------INGTPG--PPLDFLE-RF-PAS----TFFWALTALL
180 190 200
240 250 260 270 280
pF1KE6 ACCLVAF--FVLQRQPRCWEASVED-LLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYL
. .:: ..: : :: :.. . . . .:: . . . ::. :
XP_006 VASAAAFQGLLLLLPP---PPSVPTGELGSGLQVGAPGAEEEVEESSPLQEPPSQAAGTT
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE6 ---EEKAAPCCPAHLAFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVAN
. :: :. : . :.: .::::::.::.::..::: :: .:::::..:. .::
XP_006 PGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSAAN
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE6 PLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVL
::: ...: . ::: :: ::.::. ::: ::.::.:::: : : .: ::.: ::::
XP_006 PLACFLAMGVLCRSLAGLGGLSLLGVFCGGYLMALAVLSPCPPLVGTSAGVVLVVLSWVL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE6 FSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNL
: .::::: . .:. .: ::: :.:.:.::::::. ::: ... ..: : :
XP_006 CLGVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCAD
390 400 410 420 430 440
pF1KE6 HCPA
:
XP_006 PCDS
>>NP_078807 (OMIM: 607882,614707) solute carrier family (445 aa)
initn: 1085 init1: 511 opt: 544 Z-score: 664.5 bits: 132.2 E(85289): 2.8e-30
Smith-Waterman score: 1048; 43.2% identity (65.5% similar) in 472 aa overlap (4-467:11-443)
10 20 30 40 50
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANI
: :::: .::::::...::.:::::..: :::::: ::::..:.. :.:.
NP_078 MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYVSVLVALGNL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 GPLLVTLLHHFRPSCLSEVPI-IFTLLG-VGTVTCIIFAFLWNMTSWVLDGHHSIAFLVL
: :.::: ... :. .::: . .:: :::. ..: ::. .. : ::.:::.:
NP_078 GLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTA---LLASLWHHVAPVAGQLHSVAFLAL
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTE
.: :::. :.:.::::::.:.:: .: .::.:.:::.::: ..::.:: : :
NP_078 AFVLALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVGRLEC-----
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ISDSVPSPVPTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMM
: :.: ... :: ::. :: :. :: .:: :. ..
NP_078 -----P-PAP--------------INGTPG--PPLDFLE-RF-PAS----TFFWALTALL
180 190 200
240 250 260 270 280
pF1KE6 ACCLVAF--FVLQRQPRCWEASVED-LLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYL
. .:: ..: : :: :.. . . . .:: . . . ::. :
NP_078 VASAAAFQGLLLLLPP---PPSVPTGELGSGLQVGAPGAEEEVEESSPLQEPPSQAAGTT
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE6 ---EEKAAPCCPAHLAFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVAN
. :: :. : . :.: .::::::.::.::..::: :: .:::::..:. .::
NP_078 PGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSAAN
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE6 PLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVL
::: ...: . ::: :: ::.::. ::: ::.::.:::: : : .: ::.: ::::
NP_078 PLACFLAMGVLCRSLAGLGGLSLLGVFCGGYLMALAVLSPCPPLVGTSAGVVLVVLSWVL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE6 FSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNL
: .::::: . .:. .: ::: :.:.:.::::::. ::: ... ..: : :
NP_078 CLGVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCAD
390 400 410 420 430 440
pF1KE6 HCPA
:
NP_078 PCDS
>>NP_001240745 (OMIM: 607882,614707) solute carrier fami (445 aa)
initn: 1085 init1: 511 opt: 544 Z-score: 664.5 bits: 132.2 E(85289): 2.8e-30
Smith-Waterman score: 1048; 43.2% identity (65.5% similar) in 472 aa overlap (4-467:11-443)
10 20 30 40 50
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANI
: :::: .::::::...::.:::::..: :::::: ::::..:.. :.:.
NP_001 MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYVSVLVALGNL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 GPLLVTLLHHFRPSCLSEVPI-IFTLLG-VGTVTCIIFAFLWNMTSWVLDGHHSIAFLVL
: :.::: ... :. .::: . .:: :::. ..: ::. .. : ::.:::.:
NP_001 GLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTA---LLASLWHHVAPVAGQLHSVAFLAL
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTE
.: :::. :.:.::::::.:.:: .: .::.:.:::.::: ..::.:: : :
NP_001 AFVLALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVGRLEC-----
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ISDSVPSPVPTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMM
: :.: ... :: ::. :: :. :: .:: :. ..
NP_001 -----P-PAP--------------INGTPG--PPLDFLE-RF-PAS----TFFWALTALL
180 190 200
240 250 260 270 280
pF1KE6 ACCLVAF--FVLQRQPRCWEASVED-LLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYL
. .:: ..: : :: :.. . . . .:: . . . ::. :
NP_001 VASAAAFQGLLLLLPP---PPSVPTGELGSGLQVGAPGAEEEVEESSPLQEPPSQAAGTT
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE6 ---EEKAAPCCPAHLAFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVAN
. :: :. : . :.: .::::::.::.::..::: :: .:::::..:. .::
NP_001 PGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSAAN
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE6 PLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVL
::: ...: . ::: :: ::.::. ::: ::.::.:::: : : .: ::.: ::::
NP_001 PLACFLAMGVLCRSLAGLGGLSLLGVFCGGYLMALAVLSPCPPLVGTSAGVVLVVLSWVL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE6 FSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNL
: .::::: . .:. .: ::: :.:.:.::::::. ::: ... ..: : :
NP_001 CLGVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCAD
390 400 410 420 430 440
pF1KE6 HCPA
:
NP_001 PCDS
>>XP_016869308 (OMIM: 607882,614707) PREDICTED: solute c (445 aa)
initn: 1085 init1: 511 opt: 544 Z-score: 664.5 bits: 132.2 E(85289): 2.8e-30
Smith-Waterman score: 1048; 43.2% identity (65.5% similar) in 472 aa overlap (4-467:11-443)
10 20 30 40 50
pF1KE6 MAFLMHLLVCVFGMGSWVTINGLWVELPLLVMELPEGWYLPSYLTVVIQLANI
: :::: .::::::...::.:::::..: :::::: ::::..:.. :.:.
XP_016 MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYVSVLVALGNL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 GPLLVTLLHHFRPSCLSEVPI-IFTLLG-VGTVTCIIFAFLWNMTSWVLDGHHSIAFLVL
: :.::: ... :. .::: . .:: :::. ..: ::. .. : ::.:::.:
XP_016 GLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTA---LLASLWHHVAPVAGQLHSVAFLAL
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TFFLALVDCTSSVTFLPFMSRLPTYYLTTFFVGEGLSGLLPALVALAQGSGLTTCVNVTE
.: :::. :.:.::::::.:.:: .: .::.:.:::.::: ..::.:: : :
XP_016 AFVLALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVGRLEC-----
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ISDSVPSPVPTRETDIAQGVPRALVSALPGMEAPLSHLESRYLPAHFSPLVFFLLLSIMM
: :.: ... :: ::. :: :. :: .:: :. ..
XP_016 -----P-PAP--------------INGTPG--PPLDFLE-RF-PAS----TFFWALTALL
180 190 200
240 250 260 270 280
pF1KE6 ACCLVAF--FVLQRQPRCWEASVED-LLNDQVTLHSIRLREENDLGPAGMVDSSQGQGYL
. .:: ..: : :: :.. . . . .:: . . . ::. :
XP_016 VASAAAFQGLLLLLPP---PPSVPTGELGSGLQVGAPGAEEEVEESSPLQEPPSQAAGTT
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE6 ---EEKAAPCCPAHLAFVYTLVAFVNALTNGMLPSVQTYSCLSYGPVAYHLAATLSIVAN
. :: :. : . :.: .::::::.::.::..::: :: .:::::..:. .::
XP_016 PGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSAAN
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE6 PLASLVSMFLPNRSLLFLGVLSVLGTCFGGYNMAMAVMSPCPLLQGHWGGEVLIVASWVL
::: ...: . ::: :: ::.::. ::: ::.::.:::: : : .: ::.: ::::
XP_016 PLACFLAMGVLCRSLAGLGGLSLLGVFCGGYLMALAVLSPCPPLVGTSAGVVLVVLSWVL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE6 FSGCLSYVKVMLGVVLRDLSRSALLWCGAAVQLGSLLGALLMFPLVNVLRLFSSADFCNL
: .::::: . .:. .: ::: :.:.:.::::::. ::: ... ..: : :
XP_016 CLGVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCAD
390 400 410 420 430 440
pF1KE6 HCPA
:
XP_016 PCDS
469 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:30:33 2016 done: Tue Nov 8 13:30:34 2016
Total Scan time: 7.400 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]