Result of FASTA (omim) for
pFN21AE6452
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6452, 486 aa
1>>>pF1KE6452 486 - 486 aa - 486 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7481+/-0.000423; mu= 21.2396+/- 0.026
mean_var=71.2092+/-14.781, 0's: 0 Z-trim(110.6): 128 B-trim: 43 in 1/50
Lambda= 0.151987
statistics sampled from 18825 (18964) to 18825 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.222), width: 16
Scan time: 7.000
The best scores are: opt bits E(85289)
XP_016871727 (OMIM: 611910,612018) PREDICTED: mono ( 516) 3250 722.4 7.3e-208
XP_016871726 (OMIM: 611910,612018) PREDICTED: mono ( 516) 3250 722.4 7.3e-208
XP_016871728 (OMIM: 611910,612018) PREDICTED: mono ( 516) 3250 722.4 7.3e-208
NP_998771 (OMIM: 611910,612018) monocarboxylate tr ( 516) 3250 722.4 7.3e-208
NP_001257552 (OMIM: 603654) monocarboxylate transp ( 478) 916 210.6 7.9e-54
XP_005269288 (OMIM: 603654) PREDICTED: monocarboxy ( 478) 916 210.6 7.9e-54
NP_004722 (OMIM: 603654) monocarboxylate transport ( 478) 916 210.6 7.9e-54
NP_001257551 (OMIM: 603654) monocarboxylate transp ( 478) 916 210.6 7.9e-54
XP_016884174 (OMIM: 610409) PREDICTED: monocarboxy ( 504) 856 197.5 7.5e-50
NP_037488 (OMIM: 610409) monocarboxylate transport ( 504) 856 197.5 7.5e-50
XP_011537292 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 742 172.5 2.5e-42
XP_011537293 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 742 172.5 2.5e-42
XP_011537291 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 742 172.5 2.5e-42
XP_011537294 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 742 172.5 2.5e-42
XP_016875714 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 686 160.1 1e-38
XP_016875716 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 686 160.1 1e-38
XP_011537297 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 686 160.1 1e-38
XP_016875713 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 686 160.1 1e-38
XP_011537295 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 686 160.1 1e-38
XP_016875715 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 686 160.1 1e-38
NP_004198 (OMIM: 603877) monocarboxylate transport ( 465) 613 144.1 7.8e-34
NP_001193881 (OMIM: 603877) monocarboxylate transp ( 465) 613 144.1 7.8e-34
NP_001193879 (OMIM: 603877) monocarboxylate transp ( 465) 613 144.1 7.8e-34
NP_001193880 (OMIM: 603877) monocarboxylate transp ( 465) 613 144.1 7.8e-34
NP_001035887 (OMIM: 603877) monocarboxylate transp ( 465) 613 144.1 7.8e-34
NP_001035888 (OMIM: 603877) monocarboxylate transp ( 465) 613 144.1 7.8e-34
XP_011521909 (OMIM: 603877) PREDICTED: monocarboxy ( 465) 613 144.1 7.8e-34
NP_699188 (OMIM: 615765) monocarboxylate transport ( 471) 607 142.8 2e-33
XP_016879770 (OMIM: 615765) PREDICTED: monocarboxy ( 511) 607 142.9 2.1e-33
XP_005256545 (OMIM: 615765) PREDICTED: monocarboxy ( 566) 607 142.9 2.2e-33
NP_003042 (OMIM: 245340,600682,610021,616095) mono ( 500) 578 136.5 1.7e-31
NP_001159968 (OMIM: 245340,600682,610021,616095) m ( 500) 578 136.5 1.7e-31
XP_011540329 (OMIM: 245340,600682,610021,616095) P ( 500) 578 136.5 1.7e-31
XP_011540328 (OMIM: 245340,600682,610021,616095) P ( 500) 578 136.5 1.7e-31
NP_001167637 (OMIM: 603880) monocarboxylate transp ( 523) 517 123.1 1.8e-27
NP_004685 (OMIM: 603880) monocarboxylate transport ( 523) 517 123.1 1.8e-27
XP_011523763 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 517 123.1 1.8e-27
XP_016880781 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 517 123.1 1.8e-27
XP_016880780 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 517 123.1 1.8e-27
XP_005257846 (OMIM: 603880) PREDICTED: monocarboxy ( 527) 517 123.1 1.9e-27
NP_001258694 (OMIM: 603879) monocarboxylate transp ( 505) 510 121.6 5.2e-27
NP_004686 (OMIM: 603879) monocarboxylate transport ( 505) 510 121.6 5.2e-27
XP_011523764 (OMIM: 603879) PREDICTED: monocarboxy ( 532) 510 121.6 5.4e-27
XP_005257847 (OMIM: 603879) PREDICTED: monocarboxy ( 545) 510 121.6 5.5e-27
NP_004687 (OMIM: 603878) monocarboxylate transport ( 487) 494 118.1 5.8e-26
XP_005271374 (OMIM: 603878) PREDICTED: monocarboxy ( 487) 494 118.1 5.8e-26
NP_001310910 (OMIM: 614242) monocarboxylate transp ( 509) 458 110.2 1.4e-23
NP_919274 (OMIM: 614242) monocarboxylate transport ( 509) 458 110.2 1.4e-23
XP_016871373 (OMIM: 614242) PREDICTED: monocarboxy ( 509) 458 110.2 1.4e-23
XP_016871372 (OMIM: 614242) PREDICTED: monocarboxy ( 551) 458 110.2 1.5e-23
>>XP_016871727 (OMIM: 611910,612018) PREDICTED: monocarb (516 aa)
initn: 3250 init1: 3250 opt: 3250 Z-score: 3852.8 bits: 722.4 E(85289): 7.3e-208
Smith-Waterman score: 3250; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:31-516)
10 20 30
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTI
::::::::::::::::::::::::::::::
XP_016 MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 CTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 GGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 SGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNH
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 VCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 FVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE6 GLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE6 PYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDP
430 440 450 460 470 480
460 470 480
pF1KE6 KLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
::::::::::::::::::::::::::::::::::::
XP_016 KLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
490 500 510
>>XP_016871726 (OMIM: 611910,612018) PREDICTED: monocarb (516 aa)
initn: 3250 init1: 3250 opt: 3250 Z-score: 3852.8 bits: 722.4 E(85289): 7.3e-208
Smith-Waterman score: 3250; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:31-516)
10 20 30
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTI
::::::::::::::::::::::::::::::
XP_016 MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 CTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 GGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 SGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNH
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 VCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 FVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE6 GLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE6 PYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDP
430 440 450 460 470 480
460 470 480
pF1KE6 KLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
::::::::::::::::::::::::::::::::::::
XP_016 KLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
490 500 510
>>XP_016871728 (OMIM: 611910,612018) PREDICTED: monocarb (516 aa)
initn: 3250 init1: 3250 opt: 3250 Z-score: 3852.8 bits: 722.4 E(85289): 7.3e-208
Smith-Waterman score: 3250; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:31-516)
10 20 30
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTI
::::::::::::::::::::::::::::::
XP_016 MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 CTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 GGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 SGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNH
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 VCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 FVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE6 GLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE6 PYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDP
430 440 450 460 470 480
460 470 480
pF1KE6 KLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
::::::::::::::::::::::::::::::::::::
XP_016 KLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
490 500 510
>>NP_998771 (OMIM: 611910,612018) monocarboxylate transp (516 aa)
initn: 3250 init1: 3250 opt: 3250 Z-score: 3852.8 bits: 722.4 E(85289): 7.3e-208
Smith-Waterman score: 3250; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:31-516)
10 20 30
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTI
::::::::::::::::::::::::::::::
NP_998 MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 CTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 CTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 GGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 GGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 SGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 SGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNH
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 VCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 VCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 FVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 FVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE6 GLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 GLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE6 PYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 PYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDP
430 440 450 460 470 480
460 470 480
pF1KE6 KLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
::::::::::::::::::::::::::::::::::::
NP_998 KLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
490 500 510
>>NP_001257552 (OMIM: 603654) monocarboxylate transporte (478 aa)
initn: 876 init1: 578 opt: 916 Z-score: 1087.3 bits: 210.6 E(85289): 7.9e-54
Smith-Waterman score: 916; 33.3% identity (65.8% similar) in 447 aa overlap (12-450:13-450)
10 20 30 40 50
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAW
::::::::..:.. :. . : . ...:: :.: : :.. ::
NP_001 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLT
: ::. : . .:..::. :. . . .. :::: :..:.::..:. .::::.: .:
NP_001 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLI
:::.:. .::....:::: :.. .: :.::.:: . ::: : :.. :.:.:..::
NP_001 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKE--WAQTCL
::...:: :: :.::::. .. :. .:.. .:. .. :: . ::. : ..
NP_001 LGSLLLNACVAGSLMRPLGPNQT-TSKSKNKTGKTEDDS----SPKKIKTKKSTWEKVNK
190 200 210 220 230
240 250 260 270 280 290
pF1KE6 CCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGV
..:.. :.. . ..: : ...:.::: . :... .::::.:...
NP_001 ----YLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 IDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFD
.:... . : ... . .. . ::. ..:.:.: :. :. :: .. ::
NP_001 VDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 GAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCG
:. ... . ..::. .:::.:.: ... : :..::.::.::: :: : .. ::
NP_001 GSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCG
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 FSMIFSSV--LLGFA---RLIKRMRKTQ-LQFIAKESDPKLQLWTNGSVAYSVARELDQK
.. .:: :.: : ::. . :: . . ..::.:
NP_001 AIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVT
420 430 440 450 460 470
480
pF1KE6 HGEPVATAVPGYSLT
NP_001 SERETNI
>>XP_005269288 (OMIM: 603654) PREDICTED: monocarboxylate (478 aa)
initn: 876 init1: 578 opt: 916 Z-score: 1087.3 bits: 210.6 E(85289): 7.9e-54
Smith-Waterman score: 916; 33.3% identity (65.8% similar) in 447 aa overlap (12-450:13-450)
10 20 30 40 50
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAW
::::::::..:.. :. . : . ...:: :.: : :.. ::
XP_005 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLT
: ::. : . .:..::. :. . . .. :::: :..:.::..:. .::::.: .:
XP_005 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLI
:::.:. .::....:::: :.. .: :.::.:: . ::: : :.. :.:.:..::
XP_005 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKE--WAQTCL
::...:: :: :.::::. .. :. .:.. .:. .. :: . ::. : ..
XP_005 LGSLLLNACVAGSLMRPLGPNQT-TSKSKNKTGKTEDDS----SPKKIKTKKSTWEKVNK
190 200 210 220 230
240 250 260 270 280 290
pF1KE6 CCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGV
..:.. :.. . ..: : ...:.::: . :... .::::.:...
XP_005 ----YLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 IDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFD
.:... . : ... . .. . ::. ..:.:.: :. :. :: .. ::
XP_005 VDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 GAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCG
:. ... . ..::. .:::.:.: ... : :..::.::.::: :: : .. ::
XP_005 GSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCG
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 FSMIFSSV--LLGFA---RLIKRMRKTQ-LQFIAKESDPKLQLWTNGSVAYSVARELDQK
.. .:: :.: : ::. . :: . . ..::.:
XP_005 AIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVT
420 430 440 450 460 470
480
pF1KE6 HGEPVATAVPGYSLT
XP_005 SERETNI
>>NP_004722 (OMIM: 603654) monocarboxylate transporter 2 (478 aa)
initn: 876 init1: 578 opt: 916 Z-score: 1087.3 bits: 210.6 E(85289): 7.9e-54
Smith-Waterman score: 916; 33.3% identity (65.8% similar) in 447 aa overlap (12-450:13-450)
10 20 30 40 50
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAW
::::::::..:.. :. . : . ...:: :.: : :.. ::
NP_004 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLT
: ::. : . .:..::. :. . . .. :::: :..:.::..:. .::::.: .:
NP_004 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLI
:::.:. .::....:::: :.. .: :.::.:: . ::: : :.. :.:.:..::
NP_004 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKE--WAQTCL
::...:: :: :.::::. .. :. .:.. .:. .. :: . ::. : ..
NP_004 LGSLLLNACVAGSLMRPLGPNQT-TSKSKNKTGKTEDDS----SPKKIKTKKSTWEKVNK
190 200 210 220 230
240 250 260 270 280 290
pF1KE6 CCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGV
..:.. :.. . ..: : ...:.::: . :... .::::.:...
NP_004 ----YLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 IDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFD
.:... . : ... . .. . ::. ..:.:.: :. :. :: .. ::
NP_004 VDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 GAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCG
:. ... . ..::. .:::.:.: ... : :..::.::.::: :: : .. ::
NP_004 GSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCG
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 FSMIFSSV--LLGFA---RLIKRMRKTQ-LQFIAKESDPKLQLWTNGSVAYSVARELDQK
.. .:: :.: : ::. . :: . . ..::.:
NP_004 AIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVT
420 430 440 450 460 470
480
pF1KE6 HGEPVATAVPGYSLT
NP_004 SERETNI
>>NP_001257551 (OMIM: 603654) monocarboxylate transporte (478 aa)
initn: 876 init1: 578 opt: 916 Z-score: 1087.3 bits: 210.6 E(85289): 7.9e-54
Smith-Waterman score: 916; 33.3% identity (65.8% similar) in 447 aa overlap (12-450:13-450)
10 20 30 40 50
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAW
::::::::..:.. :. . : . ...:: :.: : :.. ::
NP_001 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 IHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLT
: ::. : . .:..::. :. . . .. :::: :..:.::..:. .::::.: .:
NP_001 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLI
:::.:. .::....:::: :.. .: :.::.:: . ::: : :.. :.:.:..::
NP_001 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKE--WAQTCL
::...:: :: :.::::. .. :. .:.. .:. .. :: . ::. : ..
NP_001 LGSLLLNACVAGSLMRPLGPNQT-TSKSKNKTGKTEDDS----SPKKIKTKKSTWEKVNK
190 200 210 220 230
240 250 260 270 280 290
pF1KE6 CCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGV
..:.. :.. . ..: : ...:.::: . :... .::::.:...
NP_001 ----YLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 IDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFD
.:... . : ... . .. . ::. ..:.:.: :. :. :: .. ::
NP_001 VDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 GAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCG
:. ... . ..::. .:::.:.: ... : :..::.::.::: :: : .. ::
NP_001 GSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCG
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 FSMIFSSV--LLGFA---RLIKRMRKTQ-LQFIAKESDPKLQLWTNGSVAYSVARELDQK
.. .:: :.: : ::. . :: . . ..::.:
NP_001 AIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVT
420 430 440 450 460 470
480
pF1KE6 HGEPVATAVPGYSLT
NP_001 SERETNI
>>XP_016884174 (OMIM: 610409) PREDICTED: monocarboxylate (504 aa)
initn: 864 init1: 836 opt: 856 Z-score: 1015.9 bits: 197.5 E(85289): 7.5e-50
Smith-Waterman score: 865; 36.1% identity (63.4% similar) in 435 aa overlap (8-430:8-430)
10 20 30 40 50 60
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWI
:. .::::::::.....::.:: . . . .:.:: .. : :..:::.
XP_016 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTG
::. . . .:..:.. ....:. .. ::::::.:.::.:::: : .:::: :::::
XP_016 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLIL
::.:: ..:.. :.: :: ::. :: :.: .:: . :.:. : :.:.:.:::..:.:
XP_016 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 GGFVLNLCVCGALMRPITL-----KEDHTTPEQNHVCRTQKED-----IKRVSPYSSLTK
::..:. :.:::.::: ..: . . . . . : ....:: .
XP_016 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 EWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAF
. . : : .. :.: ::. ..:: : . :: :: ..:: .:::
XP_016 RLLD--LAVCTDRA--------FAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAF
250 260 270 280 290
300 310 320 330 340
pF1KE6 LMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGM--DGLCYLCLPMLQSLPLLVP
:.::.: .::.. . : :. :. .: :::.... .:: : .: ::
XP_016 LLSIVGFVDIVARPACGALAGLARLR--PHVPYLFSLALLANGLTDLSSARARSYGALVA
300 310 320 330 340
350 360 370 380 390 400
pF1KE6 FSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGS
: .:: : .: : ::. . ::::.: ...:. :..:: ::::::. .
XP_016 FCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKN
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE6 YTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVAREL
: : : : . ...:... :
XP_016 YEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPV
410 420 430 440 450 460
>>NP_037488 (OMIM: 610409) monocarboxylate transporter 3 (504 aa)
initn: 864 init1: 836 opt: 856 Z-score: 1015.9 bits: 197.5 E(85289): 7.5e-50
Smith-Waterman score: 865; 36.1% identity (63.4% similar) in 435 aa overlap (8-430:8-430)
10 20 30 40 50 60
pF1KE6 MAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWI
:. .::::::::.....::.:: . . . .:.:: .. : :..:::.
NP_037 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTG
::. . . .:..:.. ....:. .. ::::::.:.::.:::: : .:::: :::::
NP_037 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLIL
::.:: ..:.. :.: :: ::. :: :.: .:: . :.:. : :.:.:.:::..:.:
NP_037 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 GGFVLNLCVCGALMRPITL-----KEDHTTPEQNHVCRTQKED-----IKRVSPYSSLTK
::..:. :.:::.::: ..: . . . . . : ....:: .
NP_037 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 EWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAF
. . : : .. :.: ::. ..:: : . :: :: ..:: .:::
NP_037 RLLD--LAVCTDRA--------FAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAF
250 260 270 280 290
300 310 320 330 340
pF1KE6 LMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGM--DGLCYLCLPMLQSLPLLVP
:.::.: .::.. . : :. :. .: :::.... .:: : .: ::
NP_037 LLSIVGFVDIVARPACGALAGLARLR--PHVPYLFSLALLANGLTDLSSARARSYGALVA
300 310 320 330 340
350 360 370 380 390 400
pF1KE6 FSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGS
: .:: : .: : ::. . ::::.: ...:. :..:: ::::::. .
NP_037 FCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKN
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE6 YTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVAREL
: : : : . ...:... :
NP_037 YEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPV
410 420 430 440 450 460
486 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:26:56 2016 done: Tue Nov 8 13:26:57 2016
Total Scan time: 7.000 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]