Result of FASTA (omim) for
pFN21AE6446
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6446, 505 aa
1>>>pF1KE6446 505 - 505 aa - 505 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8018+/-0.000294; mu= 16.9480+/- 0.019
mean_var=80.9361+/-16.017, 0's: 0 Z-trim(118.4): 76 B-trim: 0 in 0/53
Lambda= 0.142562
statistics sampled from 31309 (31388) to 31309 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.368), width: 16
Scan time: 8.390
The best scores are: opt bits E(85289)
NP_004686 (OMIM: 603879) monocarboxylate transport ( 505) 3436 716.0 6.2e-206
NP_001258694 (OMIM: 603879) monocarboxylate transp ( 505) 3436 716.0 6.2e-206
XP_005257847 (OMIM: 603879) PREDICTED: monocarboxy ( 545) 3436 716.0 6.7e-206
XP_011523764 (OMIM: 603879) PREDICTED: monocarboxy ( 532) 2608 545.7 1.2e-154
XP_016880782 (OMIM: 603879) PREDICTED: monocarboxy ( 435) 2305 483.4 5.8e-136
XP_005269288 (OMIM: 603654) PREDICTED: monocarboxy ( 478) 1005 216.0 1.9e-55
NP_001257551 (OMIM: 603654) monocarboxylate transp ( 478) 1005 216.0 1.9e-55
NP_001257552 (OMIM: 603654) monocarboxylate transp ( 478) 1005 216.0 1.9e-55
NP_004722 (OMIM: 603654) monocarboxylate transport ( 478) 1005 216.0 1.9e-55
XP_011537293 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 827 179.4 2.1e-44
XP_011537291 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 827 179.4 2.1e-44
XP_011537292 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 827 179.4 2.1e-44
XP_011537294 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 827 179.4 2.1e-44
XP_011537295 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 734 160.2 9.6e-39
XP_016875714 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 734 160.2 9.6e-39
XP_016875715 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 734 160.2 9.6e-39
XP_011537297 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 734 160.2 9.6e-39
XP_016875713 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 734 160.2 9.6e-39
XP_016875716 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 734 160.2 9.6e-39
NP_001035887 (OMIM: 603877) monocarboxylate transp ( 465) 659 144.8 5e-34
NP_004198 (OMIM: 603877) monocarboxylate transport ( 465) 659 144.8 5e-34
NP_001193879 (OMIM: 603877) monocarboxylate transp ( 465) 659 144.8 5e-34
NP_001193881 (OMIM: 603877) monocarboxylate transp ( 465) 659 144.8 5e-34
XP_011521909 (OMIM: 603877) PREDICTED: monocarboxy ( 465) 659 144.8 5e-34
NP_001193880 (OMIM: 603877) monocarboxylate transp ( 465) 659 144.8 5e-34
NP_001035888 (OMIM: 603877) monocarboxylate transp ( 465) 659 144.8 5e-34
NP_037488 (OMIM: 610409) monocarboxylate transport ( 504) 658 144.7 6.2e-34
XP_016884174 (OMIM: 610409) PREDICTED: monocarboxy ( 504) 658 144.7 6.2e-34
NP_003042 (OMIM: 245340,600682,610021,616095) mono ( 500) 578 128.2 5.5e-29
XP_011540328 (OMIM: 245340,600682,610021,616095) P ( 500) 578 128.2 5.5e-29
NP_001159968 (OMIM: 245340,600682,610021,616095) m ( 500) 578 128.2 5.5e-29
XP_011540329 (OMIM: 245340,600682,610021,616095) P ( 500) 578 128.2 5.5e-29
NP_061063 (OMIM: 607550) monocarboxylate transport ( 515) 537 119.8 2e-26
XP_016871728 (OMIM: 611910,612018) PREDICTED: mono ( 516) 510 114.2 9.2e-25
NP_998771 (OMIM: 611910,612018) monocarboxylate tr ( 516) 510 114.2 9.2e-25
XP_016871727 (OMIM: 611910,612018) PREDICTED: mono ( 516) 510 114.2 9.2e-25
XP_016871726 (OMIM: 611910,612018) PREDICTED: mono ( 516) 510 114.2 9.2e-25
NP_004685 (OMIM: 603880) monocarboxylate transport ( 523) 501 112.4 3.4e-24
XP_016880780 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 501 112.4 3.4e-24
NP_001167637 (OMIM: 603880) monocarboxylate transp ( 523) 501 112.4 3.4e-24
XP_011523763 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 501 112.4 3.4e-24
XP_016880781 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 501 112.4 3.4e-24
XP_005257846 (OMIM: 603880) PREDICTED: monocarboxy ( 527) 501 112.4 3.4e-24
NP_699188 (OMIM: 615765) monocarboxylate transport ( 471) 500 112.1 3.5e-24
XP_016879770 (OMIM: 615765) PREDICTED: monocarboxy ( 511) 500 112.2 3.8e-24
XP_005256545 (OMIM: 615765) PREDICTED: monocarboxy ( 566) 500 112.2 4.1e-24
NP_919274 (OMIM: 614242) monocarboxylate transport ( 509) 450 101.9 4.7e-21
NP_001310910 (OMIM: 614242) monocarboxylate transp ( 509) 450 101.9 4.7e-21
XP_016871373 (OMIM: 614242) PREDICTED: monocarboxy ( 509) 450 101.9 4.7e-21
XP_016871372 (OMIM: 614242) PREDICTED: monocarboxy ( 551) 450 101.9 5e-21
>>NP_004686 (OMIM: 603879) monocarboxylate transporter 6 (505 aa)
initn: 3436 init1: 3436 opt: 3436 Z-score: 3818.1 bits: 716.0 E(85289): 6.2e-206
Smith-Waterman score: 3436; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505)
10 20 30 40 50 60
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 AVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 ASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 QFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRT
430 440 450 460 470 480
490 500
pF1KE6 SHEWLLWPKAVLQAKQTALGWNSPT
:::::::::::::::::::::::::
NP_004 SHEWLLWPKAVLQAKQTALGWNSPT
490 500
>>NP_001258694 (OMIM: 603879) monocarboxylate transporte (505 aa)
initn: 3436 init1: 3436 opt: 3436 Z-score: 3818.1 bits: 716.0 E(85289): 6.2e-206
Smith-Waterman score: 3436; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505)
10 20 30 40 50 60
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 AVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 ASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 QFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRT
430 440 450 460 470 480
490 500
pF1KE6 SHEWLLWPKAVLQAKQTALGWNSPT
:::::::::::::::::::::::::
NP_001 SHEWLLWPKAVLQAKQTALGWNSPT
490 500
>>XP_005257847 (OMIM: 603879) PREDICTED: monocarboxylate (545 aa)
initn: 3436 init1: 3436 opt: 3436 Z-score: 3817.6 bits: 716.0 E(85289): 6.7e-206
Smith-Waterman score: 3436; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:41-545)
10 20 30
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGF
::::::::::::::::::::::::::::::
XP_005 TSQGWCPSVTPGTWAAATLAVRPWQRRQQRMPQALERADGSWAWVVLLATMVTQGLTLGF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 PTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLA
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 SLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE6 GITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPET
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE6 PALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDE
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE6 QQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWV
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE6 LVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDA
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE6 TNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQR
440 450 460 470 480 490
460 470 480 490 500
pF1KE6 SPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT
500 510 520 530 540
>>XP_011523764 (OMIM: 603879) PREDICTED: monocarboxylate (532 aa)
initn: 2608 init1: 2608 opt: 2608 Z-score: 2897.4 bits: 545.7 E(85289): 1.2e-154
Smith-Waterman score: 2608; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:41-424)
10 20 30
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGF
::::::::::::::::::::::::::::::
XP_011 TSQGWCPSVTPGTWAAATLAVRPWQRRQQRMPQALERADGSWAWVVLLATMVTQGLTLGF
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 PTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLA
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 SLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE6 GITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPET
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE6 PALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDE
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE6 QQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWV
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE6 LVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAASSSSQ
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE6 TNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQR
XP_011 LPSSWVAASTPCRRRSKASRLSRRMPWSGIFSWKPKTVLGSNGPLRSCASLPASHVQLAS
440 450 460 470 480 490
>>XP_016880782 (OMIM: 603879) PREDICTED: monocarboxylate (435 aa)
initn: 2300 init1: 2300 opt: 2305 Z-score: 2561.9 bits: 483.4 E(85289): 5.8e-136
Smith-Waterman score: 2305; 97.7% identity (98.3% similar) in 353 aa overlap (110-459:82-434)
80 90 100 110 120 130
pF1KE6 RVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFIT---GLGMCFSFQSSITVLGFYFVRR
::: . ::::::::::::::::::::::
XP_016 HGGQLLLSQPQPALLHSRIHHRWKAPVRLQAGFPSCPAGLGMCFSFQSSITVLGFYFVRR
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE6 RVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSV
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 APETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQ
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE6 VFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNG
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE6 LTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLA
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE6 FLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALER
360 370 380 390 400 410
440 450 460 470 480 490
pF1KE6 DLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQ
::::::::::::::::::: .:
XP_016 DLFLEAKDGPGKQRSPEIMYVTSV
420 430
>>XP_005269288 (OMIM: 603654) PREDICTED: monocarboxylate (478 aa)
initn: 950 init1: 588 opt: 1005 Z-score: 1116.3 bits: 216.0 E(85289): 1.9e-55
Smith-Waterman score: 1005; 34.0% identity (70.2% similar) in 450 aa overlap (2-443:8-455)
10 20 30 40 50
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSW
: . ::.:.:.:. :.... :.. .:: . .:: :.: :... :: .:
XP_005 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFIT
. ::. ::.. .::. :.::...: : .:. ::.: :::: .::: .. :::.: ::::
XP_005 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLV
:::. :..: ..:..: :: :.: .::.:: : . .. ...::....::.:.::.
XP_005 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 FGGIFLHCCICGAIIRPVA---TSVAPETKECPPPPPETPA-LGCLAACGRTIQRHLAFD
.:...:. :. :...::.. :. ..: .: . . . ....: :.
XP_005 LGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPL
...: :. .:. : . ::: : .::.::: ...:: .::.:.:...: ..: ::
XP_005 LFKHR-GFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPS
250 260 270 280 290
300 310 320 330 340 350
pF1KE6 AGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIF
.::.:. . . .:.::.:...::. .:.: . :. :: : . ............:
XP_005 VGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLF
300 310 320 330 340 350
360 370 380 390 400
pF1KE6 QVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAA-
..:::.: .: :.:: :... :..::::: :.: :....:. ::: .. ::
XP_005 ETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYM-YMSCGAIVVAAS
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE6 --LFMGGSF-YALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAG
:..:... : : ::. .. . . : . . ..:
XP_005 VWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI
420 430 440 450 460 470
470 480 490 500
pF1KE6 VNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT
>>NP_001257551 (OMIM: 603654) monocarboxylate transporte (478 aa)
initn: 950 init1: 588 opt: 1005 Z-score: 1116.3 bits: 216.0 E(85289): 1.9e-55
Smith-Waterman score: 1005; 34.0% identity (70.2% similar) in 450 aa overlap (2-443:8-455)
10 20 30 40 50
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSW
: . ::.:.:.:. :.... :.. .:: . .:: :.: :... :: .:
NP_001 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFIT
. ::. ::.. .::. :.::...: : .:. ::.: :::: .::: .. :::.: ::::
NP_001 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLV
:::. :..: ..:..: :: :.: .::.:: : . .. ...::....::.:.::.
NP_001 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 FGGIFLHCCICGAIIRPVA---TSVAPETKECPPPPPETPA-LGCLAACGRTIQRHLAFD
.:...:. :. :...::.. :. ..: .: . . . ....: :.
NP_001 LGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPL
...: :. .:. : . ::: : .::.::: ...:: .::.:.:...: ..: ::
NP_001 LFKHR-GFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPS
250 260 270 280 290
300 310 320 330 340 350
pF1KE6 AGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIF
.::.:. . . .:.::.:...::. .:.: . :. :: : . ............:
NP_001 VGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLF
300 310 320 330 340 350
360 370 380 390 400
pF1KE6 QVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAA-
..:::.: .: :.:: :... :..::::: :.: :....:. ::: .. ::
NP_001 ETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYM-YMSCGAIVVAAS
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE6 --LFMGGSF-YALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAG
:..:... : : ::. .. . . : . . ..:
NP_001 VWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI
420 430 440 450 460 470
470 480 490 500
pF1KE6 VNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT
>>NP_001257552 (OMIM: 603654) monocarboxylate transporte (478 aa)
initn: 950 init1: 588 opt: 1005 Z-score: 1116.3 bits: 216.0 E(85289): 1.9e-55
Smith-Waterman score: 1005; 34.0% identity (70.2% similar) in 450 aa overlap (2-443:8-455)
10 20 30 40 50
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSW
: . ::.:.:.:. :.... :.. .:: . .:: :.: :... :: .:
NP_001 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFIT
. ::. ::.. .::. :.::...: : .:. ::.: :::: .::: .. :::.: ::::
NP_001 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLV
:::. :..: ..:..: :: :.: .::.:: : . .. ...::....::.:.::.
NP_001 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 FGGIFLHCCICGAIIRPVA---TSVAPETKECPPPPPETPA-LGCLAACGRTIQRHLAFD
.:...:. :. :...::.. :. ..: .: . . . ....: :.
NP_001 LGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPL
...: :. .:. : . ::: : .::.::: ...:: .::.:.:...: ..: ::
NP_001 LFKHR-GFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPS
250 260 270 280 290
300 310 320 330 340 350
pF1KE6 AGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIF
.::.:. . . .:.::.:...::. .:.: . :. :: : . ............:
NP_001 VGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLF
300 310 320 330 340 350
360 370 380 390 400
pF1KE6 QVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAA-
..:::.: .: :.:: :... :..::::: :.: :....:. ::: .. ::
NP_001 ETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYM-YMSCGAIVVAAS
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE6 --LFMGGSF-YALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAG
:..:... : : ::. .. . . : . . ..:
NP_001 VWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI
420 430 440 450 460 470
470 480 490 500
pF1KE6 VNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT
>>NP_004722 (OMIM: 603654) monocarboxylate transporter 2 (478 aa)
initn: 950 init1: 588 opt: 1005 Z-score: 1116.3 bits: 216.0 E(85289): 1.9e-55
Smith-Waterman score: 1005; 34.0% identity (70.2% similar) in 450 aa overlap (2-443:8-455)
10 20 30 40 50
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSW
: . ::.:.:.:. :.... :.. .:: . .:: :.: :... :: .:
NP_004 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFIT
. ::. ::.. .::. :.::...: : .:. ::.: :::: .::: .. :::.: ::::
NP_004 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLV
:::. :..: ..:..: :: :.: .::.:: : . .. ...::....::.:.::.
NP_004 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 FGGIFLHCCICGAIIRPVA---TSVAPETKECPPPPPETPA-LGCLAACGRTIQRHLAFD
.:...:. :. :...::.. :. ..: .: . . . ....: :.
NP_004 LGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPL
...: :. .:. : . ::: : .::.::: ...:: .::.:.:...: ..: ::
NP_004 LFKHR-GFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPS
250 260 270 280 290
300 310 320 330 340 350
pF1KE6 AGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIF
.::.:. . . .:.::.:...::. .:.: . :. :: : . ............:
NP_004 VGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLF
300 310 320 330 340 350
360 370 380 390 400
pF1KE6 QVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAA-
..:::.: .: :.:: :... :..::::: :.: :....:. ::: .. ::
NP_004 ETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYM-YMSCGAIVVAAS
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE6 --LFMGGSF-YALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAG
:..:... : : ::. .. . . : . . ..:
NP_004 VWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI
420 430 440 450 460 470
470 480 490 500
pF1KE6 VNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT
>>XP_011537293 (OMIM: 603654) PREDICTED: monocarboxylate (504 aa)
initn: 773 init1: 411 opt: 827 Z-score: 918.1 bits: 179.4 E(85289): 2.1e-44
Smith-Waterman score: 943; 32.1% identity (66.4% similar) in 476 aa overlap (2-443:8-481)
10 20 30 40 50
pF1KE6 MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSW
: . ::.:.:.:. :.... :.. .:: . .:: :.: :... :: .:
XP_011 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80
pF1KE6 FPSILTAVLHMAG--------------------------PLCSILVGRFGCRVTVMLGGV
. ::. ::.. .: :. :.::...: : .:. ::.
XP_011 ISSIMLAVMYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE6 LASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGV
: :::: .::: .. :::.: :::::::. :..: ..:..: :: :.: .::.:: :
XP_011 LCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE6 SLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVA---TSVAPETKECPP
. .. ...::....::.:.::..:...:. :. :...::.. :. ..:
XP_011 PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKT
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE6 PPPETPA-LGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAM
.: . . . ....: :....: :. .:. : . ::: : .::.:::
XP_011 EDDSSPKKIKTKKSTWEKVNKYLDFSLFKHR-GFLIYLSGNVIMFLGFFAPIIFLAPYAK
250 260 270 280 290
270 280 290 300 310 320
pF1KE6 WHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAA
...:: .::.:.:...: ..: :: .::.:. . . .:.::.:...::. .:.:
XP_011 DQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPL
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE6 SGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLA
. :. :: : . ............:..:::.: .: :.:: :... :..::::
XP_011 AQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLA
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE6 GLLLDATNNFSYVFYMSSFFLISAA---LFMGGSF-YALQKKEQGKQAVAADALERDLFL
: :.: :....:. ::: .. :: :..:... : : ::. .. . . : . .
XP_011 GKLVDLTGEYKYM-YMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLS
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE6 EAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALG
..:
XP_011 KSKHSEDVNVKVSNAQSVTSERETNI
480 490 500
505 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:23:01 2016 done: Tue Nov 8 13:23:02 2016
Total Scan time: 8.390 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]