Result of FASTA (omim) for
pFN21AE6437
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6437, 558 aa
1>>>pF1KE6437 558 - 558 aa - 558 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1689+/-0.000462; mu= 19.4069+/- 0.028
mean_var=74.4199+/-16.168, 0's: 0 Z-trim(110.0): 43 B-trim: 889 in 1/49
Lambda= 0.148672
statistics sampled from 18262 (18305) to 18262 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.215), width: 16
Scan time: 6.750
The best scores are: opt bits E(85289)
NP_002013 (OMIM: 136131) dimethylaniline monooxyge ( 558) 3795 824.1 0
XP_005245102 (OMIM: 136131) PREDICTED: dimethylani ( 508) 3454 750.9 2.1e-216
XP_005245103 (OMIM: 136131) PREDICTED: dimethylani ( 495) 3052 664.7 1.9e-190
XP_011507649 (OMIM: 136131) PREDICTED: dimethylani ( 469) 2810 612.8 7.6e-175
XP_011507650 (OMIM: 136131) PREDICTED: dimethylani ( 415) 2803 611.2 2e-174
NP_001451 (OMIM: 603955) dimethylaniline monooxyge ( 535) 2032 446.0 1.4e-124
NP_001002294 (OMIM: 136132,602079) dimethylaniline ( 532) 2016 442.5 1.6e-123
NP_008825 (OMIM: 136132,602079) dimethylaniline mo ( 532) 2016 442.5 1.6e-123
XP_011507651 (OMIM: 136131) PREDICTED: dimethylani ( 278) 1911 419.8 5.7e-117
XP_005273003 (OMIM: 603957) PREDICTED: dimethylani ( 533) 1908 419.4 1.5e-116
XP_005273005 (OMIM: 603957) PREDICTED: dimethylani ( 533) 1908 419.4 1.5e-116
NP_001452 (OMIM: 603957) dimethylaniline monooxyge ( 533) 1908 419.4 1.5e-116
XP_011507652 (OMIM: 603957) PREDICTED: dimethylani ( 533) 1908 419.4 1.5e-116
XP_005273004 (OMIM: 603957) PREDICTED: dimethylani ( 533) 1908 419.4 1.5e-116
NP_002012 (OMIM: 136130) dimethylaniline monooxyge ( 532) 1884 414.2 5.2e-115
NP_001269622 (OMIM: 136130) dimethylaniline monoox ( 532) 1884 414.2 5.2e-115
NP_001269621 (OMIM: 136130) dimethylaniline monoox ( 536) 1884 414.2 5.2e-115
XP_011507647 (OMIM: 136132,602079) PREDICTED: dime ( 512) 1772 390.2 8.6e-108
NP_001306102 (OMIM: 136132,602079) dimethylaniline ( 512) 1772 390.2 8.6e-108
NP_001138301 (OMIM: 603957) dimethylaniline monoox ( 464) 1631 359.9 1e-98
NP_001306103 (OMIM: 136132,602079) dimethylaniline ( 469) 1559 344.5 4.5e-94
XP_006711305 (OMIM: 136130) PREDICTED: dimethylani ( 418) 1536 339.5 1.3e-92
XP_006711306 (OMIM: 136131) PREDICTED: dimethylani ( 381) 1513 334.5 3.6e-91
XP_005245095 (OMIM: 136130) PREDICTED: dimethylani ( 411) 1506 333.0 1.1e-90
XP_011507653 (OMIM: 603957) PREDICTED: dimethylani ( 470) 1442 319.4 1.6e-86
XP_016856291 (OMIM: 603957) PREDICTED: dimethylani ( 470) 1442 319.4 1.6e-86
XP_016856290 (OMIM: 603957) PREDICTED: dimethylani ( 470) 1442 319.4 1.6e-86
NP_001269623 (OMIM: 136130) dimethylaniline monoox ( 469) 1344 298.3 3.5e-80
XP_005245094 (OMIM: 136130) PREDICTED: dimethylani ( 436) 1334 296.2 1.4e-79
XP_006711304 (OMIM: 136130) PREDICTED: dimethylani ( 497) 1221 272.0 3.2e-72
XP_006711307 (OMIM: 603957) PREDICTED: dimethylani ( 332) 1189 265.0 2.7e-70
XP_006711308 (OMIM: 603957) PREDICTED: dimethylani ( 285) 1183 263.6 5.9e-70
NP_001138302 (OMIM: 603957) dimethylaniline monoox ( 285) 1183 263.6 5.9e-70
XP_005245105 (OMIM: 136131) PREDICTED: dimethylani ( 326) 1148 256.2 1.2e-67
NP_001288276 (OMIM: 603955) dimethylaniline monoox ( 315) 966 217.1 6.5e-56
>>NP_002013 (OMIM: 136131) dimethylaniline monooxygenase (558 aa)
initn: 3795 init1: 3795 opt: 3795 Z-score: 4400.7 bits: 824.1 E(85289): 0
Smith-Waterman score: 3795; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558)
10 20 30 40 50 60
pF1KE6 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 SVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 ERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 GARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLV
490 500 510 520 530 540
550
pF1KE6 RDKLQDRMSPYLVSLWRG
::::::::::::::::::
NP_002 RDKLQDRMSPYLVSLWRG
550
>>XP_005245102 (OMIM: 136131) PREDICTED: dimethylaniline (508 aa)
initn: 3454 init1: 3454 opt: 3454 Z-score: 4006.0 bits: 750.9 E(85289): 2.1e-216
Smith-Waterman score: 3454; 100.0% identity (100.0% similar) in 508 aa overlap (51-558:1-508)
30 40 50 60 70 80
pF1KE6 CVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPN
::::::::::::::::::::::::::::::
XP_005 MTRVYKSLVTNVCKEMSCYSDFPFHEDYPN
10 20 30
90 100 110 120 130 140
pF1KE6 FMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVF
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE6 DAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE6 VELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE6 NKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEEN
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE6 IDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSG
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE6 TELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVFKDTSKDKFDYIAYMDDIAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVFKDTSKDKFDYIAYMDDIAAC
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE6 IGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTR
400 410 420 430 440 450
510 520 530 540 550
pF1KE6 IVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLVRDKLQDRMSPYLVSLWRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLVRDKLQDRMSPYLVSLWRG
460 470 480 490 500
>>XP_005245103 (OMIM: 136131) PREDICTED: dimethylaniline (495 aa)
initn: 3051 init1: 3051 opt: 3052 Z-score: 3540.2 bits: 664.7 E(85289): 1.9e-190
Smith-Waterman score: 3209; 88.7% identity (88.7% similar) in 558 aa overlap (1-558:1-495)
10 20 30 40 50 60
pF1KE6 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFT----------------
10 20 30 40
70 80 90 100 110 120
pF1KE6 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
:::::::::::::
XP_005 -----------------------------------------------TTVCSITKRPDFS
50
130 140 150 160 170 180
pF1KE6 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE6 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE6 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKT
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE6 SVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNL
240 250 260 270 280 290
370 380 390 400 410 420
pF1KE6 ERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVF
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE6 KDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWD
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE6 GARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLV
420 430 440 450 460 470
550
pF1KE6 RDKLQDRMSPYLVSLWRG
::::::::::::::::::
XP_005 RDKLQDRMSPYLVSLWRG
480 490
>>XP_011507649 (OMIM: 136131) PREDICTED: dimethylaniline (469 aa)
initn: 2810 init1: 2810 opt: 2810 Z-score: 3260.0 bits: 612.8 E(85289): 7.6e-175
Smith-Waterman score: 2810; 100.0% identity (100.0% similar) in 416 aa overlap (1-416:1-416)
10 20 30 40 50 60
pF1KE6 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 SVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 ERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKSCSI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 KDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWD
XP_011 WTDQTLFSHQIQELKTLFKVSLEFLRTYNYLWRKSSPRMIFLIDSILVF
430 440 450 460
>>XP_011507650 (OMIM: 136131) PREDICTED: dimethylaniline (415 aa)
initn: 2803 init1: 2803 opt: 2803 Z-score: 3252.6 bits: 611.2 E(85289): 2e-174
Smith-Waterman score: 2803; 100.0% identity (100.0% similar) in 415 aa overlap (144-558:1-415)
120 130 140 150 160 170
pF1KE6 TKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHS
::::::::::::::::::::::::::::::
XP_011 MVCTGHFLNPHLPLEAFPGIHKFKGQILHS
10 20 30
180 190 200 210 220 230
pF1KE6 QEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNM
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE6 MVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILC
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE6 GAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYK
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE6 QVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQ
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE6 LIKRGVFKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKRGVFKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRL
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE6 MGPGKWDGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGPGKWDGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKS
340 350 360 370 380 390
540 550
pF1KE6 SLFLKLVRDKLQDRMSPYLVSLWRG
:::::::::::::::::::::::::
XP_011 SLFLKLVRDKLQDRMSPYLVSLWRG
400 410
>>NP_001451 (OMIM: 603955) dimethylaniline monooxygenase (535 aa)
initn: 1995 init1: 1209 opt: 2032 Z-score: 2357.3 bits: 446.0 E(85289): 1.4e-124
Smith-Waterman score: 2032; 55.5% identity (82.1% similar) in 537 aa overlap (1-532:1-531)
10 20 30 40 50 60
pF1KE6 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
::::::::::::::: :.:::::: ::::::::..::::.:.: :. .:: . .:.:.::
NP_001 MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
:. :::::.::::. ::.:::... :. .:.. ::..:::::::::.::: :. : ::::
NP_001 NTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
.::: :::...::.. :::::::::.:: . ::.::..:::...:::: .::..:: :.
NP_001 SSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
::.:::.::::.::.:.:::::::..::::..::: ::::..: :. :::.. . :
NP_001 GFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFR
190 200 210 220 230 240
250 260 270 280 290
pF1KE6 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKF-IVNDELPNCILCGAITMK
:.. .::: ..:. :...:. ::::.::: . : ..::..:. .::::: .:
NP_001 SMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 TSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLN
..: :.:::::.::::::::::::.::.:::.:::::.:. : .. .. . ::: .:: .
NP_001 STVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAH
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 LERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKR-G
:...::: :::: :::. .:::::::::::::::..: . .::. .... ::
NP_001 LDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNE--KRID
370 380 390 400 410
420 430 440 450 460 470
pF1KE6 VFKDTSKDKF--DYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGP
.: ..... . .:. :.:..: ::.::.. :..:::.:: ...::::. :::::.::
NP_001 LFGESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSYQYRLVGP
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 GKWDGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLL-LICKSSL
:.:.::::::.:: .: ::::::: . :::. :.: :: : ::: .. ..:.
NP_001 GQWEGARNAIFTQKQRILKPLKTRALKDSSN-FSVSFLLKILG---LLAVVVAFFCQLQW
480 490 500 510 520 530
540 550
pF1KE6 FLKLVRDKLQDRMSPYLVSLWRG
NP_001 S
>>NP_001002294 (OMIM: 136132,602079) dimethylaniline mon (532 aa)
initn: 1891 init1: 1472 opt: 2016 Z-score: 2338.8 bits: 442.5 E(85289): 1.6e-123
Smith-Waterman score: 2016; 52.5% identity (80.6% similar) in 531 aa overlap (1-530:1-530)
10 20 30 40 50 60
pF1KE6 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
:.::::.::::::::.::. :..: :::::::.:.::::::::.. ...: . .:::. .
NP_001 MGKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
: ::: :. :::: .:.::::.. :. .:. ::.. .::::::::: : :..:.:::.
NP_001 NSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
::::::.:: .::.. :::::::::.:: . :.:: :.:::...:::. .::..:: :
NP_001 TTGQWDVTTERDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
:.::::::.::::.: :::.:::::: ::..:.:.:.::..: : :::..:... :
NP_001 VFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFG
190 200 210 220 230 240
250 260 270 280 290
pF1KE6 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGK-KAKFIVNDELPNCILCGAITMK
.:. . ::. . .:. ...: ::.::.::: .: . . . ::::: :::: ...:
NP_001 TFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 TSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLN
.: :::::::.:::::. :.:: :::.:::.:..::..: . . ...:.:.: :::
NP_001 PNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEIILFKGVFPPL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 LERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGV
::..:.:.::.. :. . ..::.::...:.:: : .: . .: . .:: . ::
NP_001 LEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEK-KRKW
370 380 390 400 410
420 430 440 450 460 470
pF1KE6 FKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKW
: . . :::.:::.... ::.::.:: ::: ::.:: ::.::::.:::.::.:::.:
NP_001 FGKSETIQTDYIVYMDELSSFIGAKPNIPWLFLTDPKLAMEVYFGPCSPYQFRLVGPGQW
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 DGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKL
::::::::::::.:::..::.: .:: . :.:: .. :.:: ...:.
NP_001 PGARNAILTQWDRSLKPMQTRVVGRLQKPCFFFHWLKLFAIPILLIAVFLVLT
480 490 500 510 520 530
540 550
pF1KE6 VRDKLQDRMSPYLVSLWRG
>>NP_008825 (OMIM: 136132,602079) dimethylaniline monoox (532 aa)
initn: 1891 init1: 1472 opt: 2016 Z-score: 2338.8 bits: 442.5 E(85289): 1.6e-123
Smith-Waterman score: 2016; 52.5% identity (80.6% similar) in 531 aa overlap (1-530:1-530)
10 20 30 40 50 60
pF1KE6 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
:.::::.::::::::.::. :..: :::::::.:.::::::::.. ...: . .:::. .
NP_008 MGKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
: ::: :. :::: .:.::::.. :. .:. ::.. .::::::::: : :..:.:::.
NP_008 NSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
::::::.:: .::.. :::::::::.:: . :.:: :.:::...:::. .::..:: :
NP_008 TTGQWDVTTERDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
:.::::::.::::.: :::.:::::: ::..:.:.:.::..: : :::..:... :
NP_008 VFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFG
190 200 210 220 230 240
250 260 270 280 290
pF1KE6 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGK-KAKFIVNDELPNCILCGAITMK
.:. . ::. . .:. ...: ::.::.::: .: . . . ::::: :::: ...:
NP_008 TFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 TSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLN
.: :::::::.:::::. :.:: :::.:::.:..::..: . . ...:.:.: :::
NP_008 PNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEIILFKGVFPPL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 LERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGV
::..:.:.::.. :. . ..::.::...:.:: : .: . .: . .:: . ::
NP_008 LEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEK-KRKW
370 380 390 400 410
420 430 440 450 460 470
pF1KE6 FKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKW
: . . :::.:::.... ::.::.:: ::: ::.:: ::.::::.:::.::.:::.:
NP_008 FGKSETIQTDYIVYMDELSSFIGAKPNIPWLFLTDPKLAMEVYFGPCSPYQFRLVGPGQW
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 DGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKL
::::::::::::.:::..::.: .:: . :.:: .. :.:: ...:.
NP_008 PGARNAILTQWDRSLKPMQTRVVGRLQKPCFFFHWLKLFAIPILLIAVFLVLT
480 490 500 510 520 530
540 550
pF1KE6 VRDKLQDRMSPYLVSLWRG
>>XP_011507651 (OMIM: 136131) PREDICTED: dimethylaniline (278 aa)
initn: 1911 init1: 1911 opt: 1911 Z-score: 2221.0 bits: 419.8 E(85289): 5.7e-117
Smith-Waterman score: 1911; 100.0% identity (100.0% similar) in 276 aa overlap (1-276:1-276)
10 20 30 40 50 60
pF1KE6 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKT
::::::::::::::::::::::::::::::::::::
XP_011 SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGTS
250 260 270
310 320 330 340 350 360
pF1KE6 SVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNL
>>XP_005273003 (OMIM: 603957) PREDICTED: dimethylaniline (533 aa)
initn: 1895 init1: 1339 opt: 1908 Z-score: 2213.6 bits: 419.4 E(85289): 1.5e-116
Smith-Waterman score: 1908; 53.9% identity (80.2% similar) in 510 aa overlap (3-510:4-512)
10 20 30 40 50
pF1KE6 MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLV
:..::::.::::::::::::.: :::.::::.:::::::.: :. ..: . .:::..
XP_005 MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 TNVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDF
:. ::: :.::.:. . :::::.. . .:.. .:..:::::::.:::::::. :.:::
XP_005 INTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 SETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIP
. .:::.::::.:::.. :::.::::::: : :::::.::::.::::: .::..:: :
XP_005 ATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 EGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRC
::: ::::..::.::.:::.:::.:.:: ::.:::: :.:.:.: .:.::: ... . :
XP_005 EGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 CSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKF-IVNDELPNCILCGAITM
:: .. . . : :.:.:.::.:: .::. . .. .::.::: :. : . .
XP_005 THFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 KTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPL
: .: :::::.:.::::. :..::.:::.:::.:.:::.:. .: . .:: :::.:::
XP_005 KGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVK-VVKNKISLYKKVFPP
310 320 330 340 350
360 370 380 390 400 410
pF1KE6 NLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATE-KEQLIKR
:::: :::::::: :.:. .:::.::.:.::::: .: ....: : .. .:.. ::
XP_005 NLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKR
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 GVFKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPG
: .. . ::: :...: .:..:.. : . ::.:: ....::::: .::..:::
XP_005 YVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPG
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 KWDGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFL
::::::.:::: :: ::: ::.: ::. .:
XP_005 KWDGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAYF
480 490 500 510 520 530
540 550
pF1KE6 KLVRDKLQDRMSPYLVSLWRG
558 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:17:12 2016 done: Tue Nov 8 13:17:14 2016
Total Scan time: 6.750 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]