Result of FASTA (omim) for
pFN21AE6434
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6434, 548 aa
1>>>pF1KE6434 548 - 548 aa - 548 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8436+/-0.000408; mu= 21.5987+/- 0.025
mean_var=75.7123+/-15.926, 0's: 0 Z-trim(111.9): 221 B-trim: 0 in 0/51
Lambda= 0.147398
statistics sampled from 20434 (20675) to 20434 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.242), width: 16
Scan time: 7.580
The best scores are: opt bits E(85289)
NP_696961 (OMIM: 604995) solute carrier family 22 ( 548) 3611 777.9 0
XP_006715033 (OMIM: 604995) PREDICTED: solute carr ( 551) 3595 774.5 0
NP_006663 (OMIM: 604995) solute carrier family 22 ( 546) 3585 772.3 0
XP_006715034 (OMIM: 604995) PREDICTED: solute carr ( 549) 3569 768.9 0
XP_011512559 (OMIM: 604995) PREDICTED: solute carr ( 607) 2698 583.8 5.3e-166
XP_016865689 (OMIM: 604995) PREDICTED: solute carr ( 543) 2682 580.3 5.2e-165
XP_011512558 (OMIM: 604995) PREDICTED: solute carr ( 610) 2682 580.4 5.6e-165
XP_011512563 (OMIM: 604995) PREDICTED: solute carr ( 420) 2680 579.8 5.8e-165
XP_016865690 (OMIM: 604995) PREDICTED: solute carr ( 420) 2680 579.8 5.8e-165
XP_016865687 (OMIM: 604995) PREDICTED: solute carr ( 602) 2566 555.7 1.5e-157
XP_011512565 (OMIM: 604995) PREDICTED: solute carr ( 352) 2297 498.3 1.7e-140
XP_016865688 (OMIM: 604995) PREDICTED: solute carr ( 557) 2167 470.8 4.9e-132
XP_011512561 (OMIM: 604995) PREDICTED: solute carr ( 585) 2136 464.2 4.9e-130
NP_004781 (OMIM: 607582) solute carrier family 22 ( 563) 1293 285.0 4.4e-76
XP_016874051 (OMIM: 607582) PREDICTED: solute carr ( 551) 1288 283.9 9e-76
NP_695008 (OMIM: 607582) solute carrier family 22 ( 550) 1284 283.0 1.6e-75
NP_653186 (OMIM: 220150,607096) solute carrier fam ( 553) 1078 239.2 2.5e-62
NP_060954 (OMIM: 607097) solute carrier family 22 ( 550) 1009 224.6 6.5e-58
NP_001171661 (OMIM: 607581) solute carrier family ( 542) 1003 223.3 1.6e-57
NP_004245 (OMIM: 607581) solute carrier family 22 ( 542) 1003 223.3 1.6e-57
NP_001171662 (OMIM: 607581) solute carrier family ( 451) 1002 223.0 1.6e-57
NP_001129978 (OMIM: 611698) solute carrier family ( 552) 987 219.9 1.7e-56
NP_695010 (OMIM: 607582) solute carrier family 22 ( 519) 936 209.0 2.9e-53
NP_695009 (OMIM: 607582) solute carrier family 22 ( 506) 935 208.8 3.3e-53
XP_011543318 (OMIM: 607580) PREDICTED: solute carr ( 541) 933 208.4 4.7e-53
NP_001034841 (OMIM: 607580) solute carrier family ( 541) 933 208.4 4.7e-53
NP_003051 (OMIM: 212140,603377) solute carrier fam ( 557) 926 206.9 1.4e-52
XP_011512564 (OMIM: 604995) PREDICTED: solute carr ( 359) 917 204.8 3.7e-52
XP_011543666 (OMIM: 607581) PREDICTED: solute carr ( 419) 912 203.8 8.7e-52
NP_001171665 (OMIM: 607581) solute carrier family ( 419) 912 203.8 8.7e-52
NP_004247 (OMIM: 604047) solute carrier family 22 ( 551) 900 201.4 6.2e-51
NP_149116 (OMIM: 608276) solute carrier family 22 ( 577) 895 200.3 1.3e-50
NP_543142 (OMIM: 607579) solute carrier family 22 ( 553) 879 196.9 1.4e-49
NP_955384 (OMIM: 610792) solute carrier family 22 ( 547) 874 195.8 2.8e-49
XP_016873176 (OMIM: 610792) PREDICTED: solute carr ( 547) 874 195.8 2.8e-49
NP_003050 (OMIM: 180300,604190) solute carrier fam ( 551) 855 191.8 4.7e-48
XP_011534507 (OMIM: 608276) PREDICTED: solute carr ( 515) 845 189.6 2e-47
NP_003049 (OMIM: 602608) solute carrier family 22 ( 555) 826 185.6 3.4e-46
XP_011534506 (OMIM: 608276) PREDICTED: solute carr ( 534) 824 185.2 4.4e-46
NP_060890 (OMIM: 608275) solute carrier family 22 ( 547) 812 182.7 2.6e-45
NP_068812 (OMIM: 604842) solute carrier family 22 ( 556) 802 180.5 1.2e-44
XP_016873188 (OMIM: 607580) PREDICTED: solute carr ( 489) 799 179.8 1.7e-44
NP_003048 (OMIM: 602607) solute carrier family 22 ( 554) 775 174.8 6.2e-43
NP_001295051 (OMIM: 212140,603377) solute carrier ( 581) 758 171.2 7.9e-42
XP_005267163 (OMIM: 604842) PREDICTED: solute carr ( 425) 743 167.9 5.8e-41
XP_016873264 (OMIM: 611696) PREDICTED: solute carr ( 354) 741 167.4 6.8e-41
XP_016873265 (OMIM: 611696) PREDICTED: solute carr ( 323) 734 165.9 1.8e-40
XP_011534377 (OMIM: 604842) PREDICTED: solute carr ( 404) 728 164.7 5.1e-40
XP_011534378 (OMIM: 604842) PREDICTED: solute carr ( 404) 728 164.7 5.1e-40
XP_016866692 (OMIM: 604842) PREDICTED: solute carr ( 404) 728 164.7 5.1e-40
>>NP_696961 (OMIM: 604995) solute carrier family 22 memb (548 aa)
initn: 3611 init1: 3611 opt: 3611 Z-score: 4151.1 bits: 777.9 E(85289): 0
Smith-Waterman score: 3611; 100.0% identity (100.0% similar) in 548 aa overlap (1-548:1-548)
10 20 30 40 50 60
pF1KE6 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 HSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 TGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 TGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 CARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 CARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 YYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 YYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 LLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 PLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_696 PLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEE
490 500 510 520 530 540
pF1KE6 MPMKQVQN
::::::::
NP_696 MPMKQVQN
>>XP_006715033 (OMIM: 604995) PREDICTED: solute carrier (551 aa)
initn: 3597 init1: 2159 opt: 3595 Z-score: 4132.7 bits: 774.5 E(85289): 0
Smith-Waterman score: 3595; 99.5% identity (99.5% similar) in 551 aa overlap (1-548:1-551)
10 20 30 40 50 60
pF1KE6 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPL---ELEWLDVEHRTVAGVLSS
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_006 STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVLSS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 TFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRY
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 LLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 NFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAF
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 GTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE6 SLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQ
490 500 510 520 530 540
540
pF1KE6 EEEMPMKQVQN
:::::::::::
XP_006 EEEMPMKQVQN
550
>>NP_006663 (OMIM: 604995) solute carrier family 22 memb (546 aa)
initn: 2698 init1: 2698 opt: 3585 Z-score: 4121.2 bits: 772.3 E(85289): 0
Smith-Waterman score: 3585; 99.6% identity (99.6% similar) in 548 aa overlap (1-548:1-546)
10 20 30 40 50 60
pF1KE6 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HSEFSSTIATE--WDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
130 140 150 160 170
190 200 210 220 230 240
pF1KE6 STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFW
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 TGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLH
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 CARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 YYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 LLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE6 PLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEE
480 490 500 510 520 530
pF1KE6 MPMKQVQN
::::::::
NP_006 MPMKQVQN
540
>>XP_006715034 (OMIM: 604995) PREDICTED: solute carrier (549 aa)
initn: 3050 init1: 2159 opt: 3569 Z-score: 4102.8 bits: 768.9 E(85289): 0
Smith-Waterman score: 3569; 99.1% identity (99.1% similar) in 551 aa overlap (1-548:1-549)
10 20 30 40 50 60
pF1KE6 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSEFSSTIATE--WDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
130 140 150 160 170
190 200 210 220 230
pF1KE6 STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPL---ELEWLDVEHRTVAGVLSS
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_006 STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVLSS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 TFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 LLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 NFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 GTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGG
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 SLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQ
480 490 500 510 520 530
540
pF1KE6 EEEMPMKQVQN
:::::::::::
XP_006 EEEMPMKQVQN
540
>>XP_011512559 (OMIM: 604995) PREDICTED: solute carrier (607 aa)
initn: 2696 init1: 2696 opt: 2698 Z-score: 3101.2 bits: 583.8 E(85289): 5.3e-166
Smith-Waterman score: 3304; 89.8% identity (89.8% similar) in 580 aa overlap (28-548:28-607)
10 20 30 40 50 60
pF1KE6 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
:::::::::::::::::::::::::::::::::
XP_011 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
70 80 90 100 110 120
130
pF1KE6 HSEFSSTIATESQ-----------------------------------------------
:::::::::::::
XP_011 HSEFSSTIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSW
130 140 150 160 170 180
140 150 160 170 180
pF1KE6 ------------WDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RESLGGLLSGMEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVS
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE6 TLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWT
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE6 GGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHC
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE6 ARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSY
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE6 YGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRL
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE6 LVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAP
490 500 510 520 530 540
490 500 510 520 530 540
pF1KE6 LAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEEM
550 560 570 580 590 600
pF1KE6 PMKQVQN
:::::::
XP_011 PMKQVQN
>>XP_016865689 (OMIM: 604995) PREDICTED: solute carrier (543 aa)
initn: 2682 init1: 2159 opt: 2682 Z-score: 3083.5 bits: 580.3 E(85289): 5.2e-165
Smith-Waterman score: 2859; 88.1% identity (88.1% similar) in 523 aa overlap (88-548:21-543)
60 70 80 90 100 110
pF1KE6 FSHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGW
::::::::::::::::::::::::::::::
XP_016 MGHGDGVTTKLTSQELQSVMALPNTTLGEERQSRGELEDEPATVPCSQGW
10 20 30 40 50
120 130
pF1KE6 EYDHSEFSSTIATESQ--------------------------------------------
::::::::::::::::
XP_016 EYDHSEFSSTIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYS
60 70 80 90 100 110
140 150 160 170
pF1KE6 ---------------WDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVA
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSWRESLGGLLSGMEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 YVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPL---ELEWLDVEHRTVAGVL
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_016 YVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 SSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 GVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTAL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 AFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 GGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTS
480 490 500 510 520 530
540
pF1KE6 LQEEEMPMKQVQN
:::::::::::::
XP_016 LQEEEMPMKQVQN
540
>>XP_011512558 (OMIM: 604995) PREDICTED: solute carrier (610 aa)
initn: 3062 init1: 2159 opt: 2682 Z-score: 3082.8 bits: 580.4 E(85289): 5.6e-165
Smith-Waterman score: 3271; 89.3% identity (89.3% similar) in 580 aa overlap (31-548:31-610)
10 20 30 40 50 60
pF1KE6 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
::::::::::::::::::::::::::::::
XP_011 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
70 80 90 100 110 120
130
pF1KE6 HSEFSSTIATESQ-----------------------------------------------
:::::::::::::
XP_011 HSEFSSTIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSW
130 140 150 160 170 180
140 150 160 170 180
pF1KE6 ------------WDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RESLGGLLSGMEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVS
190 200 210 220 230 240
190 200 210 220 230
pF1KE6 TLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPL---ELEWLDVEHRTVAGVLSST
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 TLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVLSST
250 260 270 280 290 300
240 250 260 270 280 290
pF1KE6 FWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYL
310 320 330 340 350 360
300 310 320 330 340 350
pF1KE6 LHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVN
370 380 390 400 410 420
360 370 380 390 400 410
pF1KE6 FSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFG
430 440 450 460 470 480
420 430 440 450 460 470
pF1KE6 TRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGS
490 500 510 520 530 540
480 490 500 510 520 530
pF1KE6 LAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQE
550 560 570 580 590 600
540
pF1KE6 EEMPMKQVQN
::::::::::
XP_011 EEMPMKQVQN
610
>>XP_011512563 (OMIM: 604995) PREDICTED: solute carrier (420 aa)
initn: 2682 init1: 2159 opt: 2680 Z-score: 3082.6 bits: 579.8 E(85289): 5.8e-165
Smith-Waterman score: 2680; 99.0% identity (99.3% similar) in 419 aa overlap (133-548:2-420)
110 120 130 140 150 160
pF1KE6 ELEDEPATVPCSQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAF
.:::::::::::::::::::::::::::::
XP_011 MEWDLVCEQKGLNRAASTFFFAGVLVGAVAF
10 20 30
170 180 190 200 210
pF1KE6 GYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPL---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLGEA
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE6 ELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVP
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE6 ESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFR
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE6 TPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRY
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE6 AGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPT
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE6 VLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQ
340 350 360 370 380 390
520 530 540
pF1KE6 LPETIQDVERKSAPTSLQEEEMPMKQVQN
:::::::::::::::::::::::::::::
XP_011 LPETIQDVERKSAPTSLQEEEMPMKQVQN
400 410 420
>>XP_016865690 (OMIM: 604995) PREDICTED: solute carrier (420 aa)
initn: 2682 init1: 2159 opt: 2680 Z-score: 3082.6 bits: 579.8 E(85289): 5.8e-165
Smith-Waterman score: 2680; 99.0% identity (99.3% similar) in 419 aa overlap (133-548:2-420)
110 120 130 140 150 160
pF1KE6 ELEDEPATVPCSQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAF
.:::::::::::::::::::::::::::::
XP_016 MEWDLVCEQKGLNRAASTFFFAGVLVGAVAF
10 20 30
170 180 190 200 210
pF1KE6 GYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPL---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLGEA
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE6 ELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVP
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE6 ESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFR
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE6 TPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRY
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE6 AGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPT
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE6 VLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQ
340 350 360 370 380 390
520 530 540
pF1KE6 LPETIQDVERKSAPTSLQEEEMPMKQVQN
:::::::::::::::::::::::::::::
XP_016 LPETIQDVERKSAPTSLQEEEMPMKQVQN
400 410 420
>>XP_016865687 (OMIM: 604995) PREDICTED: solute carrier (602 aa)
initn: 2946 init1: 2043 opt: 2566 Z-score: 2949.6 bits: 555.7 E(85289): 1.5e-157
Smith-Waterman score: 3155; 89.0% identity (89.0% similar) in 562 aa overlap (31-530:31-592)
10 20 30 40 50 60
pF1KE6 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
::::::::::::::::::::::::::::::
XP_016 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
70 80 90 100 110 120
130
pF1KE6 HSEFSSTIATESQ-----------------------------------------------
:::::::::::::
XP_016 HSEFSSTIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSW
130 140 150 160 170 180
140 150 160 170 180
pF1KE6 ------------WDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RESLGGLLSGMEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVS
190 200 210 220 230 240
190 200 210 220 230
pF1KE6 TLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPL---ELEWLDVEHRTVAGVLSST
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 TLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVLSST
250 260 270 280 290 300
240 250 260 270 280 290
pF1KE6 FWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYL
310 320 330 340 350 360
300 310 320 330 340 350
pF1KE6 LHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVN
370 380 390 400 410 420
360 370 380 390 400 410
pF1KE6 FSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFG
430 440 450 460 470 480
420 430 440 450 460 470
pF1KE6 TRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGS
490 500 510 520 530 540
480 490 500 510 520 530
pF1KE6 LAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKRDGAKERT
550 560 570 580 590 600
540
pF1KE6 EEMPMKQVQN
XP_016 SI
548 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:16:02 2016 done: Tue Nov 8 13:16:03 2016
Total Scan time: 7.580 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]