Result of FASTA (omim) for
pFN21AE6424
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6424, 553 aa
1>>>pF1KE6424 553 - 553 aa - 553 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4356+/-0.000343; mu= 2.6308+/- 0.022
mean_var=257.7328+/-52.407, 0's: 0 Z-trim(123.5): 17 B-trim: 1425 in 1/57
Lambda= 0.079889
statistics sampled from 43370 (43388) to 43370 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.509), width: 16
Scan time: 9.730
The best scores are: opt bits E(85289)
NP_076988 (OMIM: 606236,606243) tether containing ( 553) 3737 443.6 7.7e-124
XP_011521903 (OMIM: 606236,606243) PREDICTED: teth ( 635) 3716 441.2 4.6e-123
XP_011521904 (OMIM: 606236,606243) PREDICTED: teth ( 620) 3652 433.8 7.5e-121
XP_016880533 (OMIM: 606236,606243) PREDICTED: teth ( 476) 3219 383.8 6.5e-106
NP_001238817 (OMIM: 606236,606243) tether containi ( 647) 3081 368.0 5e-101
XP_016880531 (OMIM: 606236,606243) PREDICTED: teth ( 578) 2953 353.2 1.3e-96
XP_016880526 (OMIM: 606236,606243) PREDICTED: teth ( 645) 2953 353.3 1.4e-96
XP_016880525 (OMIM: 606236,606243) PREDICTED: teth ( 660) 2953 353.3 1.4e-96
NP_001317457 (OMIM: 606236,606243) tether containi ( 501) 2435 293.5 1.1e-78
XP_016880529 (OMIM: 606236,606243) PREDICTED: teth ( 583) 2435 293.5 1.2e-78
XP_016880528 (OMIM: 606236,606243) PREDICTED: teth ( 583) 2435 293.5 1.2e-78
XP_016880527 (OMIM: 606236,606243) PREDICTED: teth ( 583) 2435 293.5 1.2e-78
XP_016880530 (OMIM: 606236,606243) PREDICTED: teth ( 583) 2435 293.5 1.2e-78
NP_001164562 (OMIM: 611946) UBX domain-containing ( 388) 243 40.7 0.01
>>NP_076988 (OMIM: 606236,606243) tether containing UBX (553 aa)
initn: 3737 init1: 3737 opt: 3737 Z-score: 2344.3 bits: 443.6 E(85289): 7.7e-124
Smith-Waterman score: 3737; 99.8% identity (99.8% similar) in 553 aa overlap (1-553:1-553)
10 20 30 40 50 60
pF1KE6 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 PFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 RSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 RSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 ISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 ISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLG
490 500 510 520 530 540
550
pF1KE6 KVPKWLKLPASKR
:::::::::::::
NP_076 KVPKWLKLPASKR
550
>>XP_011521903 (OMIM: 606236,606243) PREDICTED: tether c (635 aa)
initn: 3833 init1: 3716 opt: 3716 Z-score: 2330.4 bits: 441.2 E(85289): 4.6e-123
Smith-Waterman score: 3716; 99.5% identity (99.8% similar) in 551 aa overlap (1-551:1-551)
10 20 30 40 50 60
pF1KE6 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 RSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 ISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLG
490 500 510 520 530 540
550
pF1KE6 KVPKWLKLPASKR
:::::::::..
XP_011 KVPKWLKLPGTAAGWKPARGESCQPEVPTPPATGPPPLPAGIKTCASLNAFLSCFLQKRA
550 560 570 580 590 600
>>XP_011521904 (OMIM: 606236,606243) PREDICTED: tether c (620 aa)
initn: 3652 init1: 3652 opt: 3652 Z-score: 2290.7 bits: 433.8 E(85289): 7.5e-121
Smith-Waterman score: 3652; 99.8% identity (99.8% similar) in 541 aa overlap (1-541:1-541)
10 20 30 40 50 60
pF1KE6 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 RSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 ISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLG
490 500 510 520 530 540
550
pF1KE6 KVPKWLKLPASKR
:
XP_011 KPARGESCQPEVPTPPATGPPPLPAGIKTCASLNAFLSCFLQKRAPVVCPGSAGPQCPGL
550 560 570 580 590 600
>>XP_016880533 (OMIM: 606236,606243) PREDICTED: tether c (476 aa)
initn: 3219 init1: 3219 opt: 3219 Z-score: 2022.5 bits: 383.8 E(85289): 6.5e-106
Smith-Waterman score: 3219; 99.8% identity (99.8% similar) in 476 aa overlap (78-553:1-476)
50 60 70 80 90 100
pF1KE6 CEYDLKFQRSVLDLSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDS
::::::::::::::::::::::::::::::
XP_016 MVPASRSREGPENMVRIALQLDDGSRLQDS
10 20 30
110 120 130 140 150 160
pF1KE6 FCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSAT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 IRFVMKCYDPVGKTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRFVMKCYDPVGKTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEH
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 TQEKQSTRAPAAAPFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKS
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 TQEKQSTRAPAAAPFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE6 GQDPQQEQEQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQDPQQEQEQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFEL
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE6 TVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFF
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE6 RPSETVGDLRDFVRSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSETVGDLRDFVRSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALVHLGAEEP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE6 AGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGALVPPEP
400 410 420 430 440 450
530 540 550
pF1KE6 IPGTAQPVKRSLGKVPKWLKLPASKR
::::::::::::::::::::::::::
XP_016 IPGTAQPVKRSLGKVPKWLKLPASKR
460 470
>>NP_001238817 (OMIM: 606236,606243) tether containing U (647 aa)
initn: 3057 init1: 3057 opt: 3081 Z-score: 1934.7 bits: 368.0 E(85289): 5e-101
Smith-Waterman score: 3109; 83.8% identity (83.8% similar) in 585 aa overlap (1-491:1-585)
10 20 30 40 50 60
pF1KE6 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
370 380 390 400 410 420
430 440 450
pF1KE6 RSHLGNPELSFYLFITPPKTVLDDHTQTLFQ-----------------------------
:::::::::::::::::::::::::::::::
NP_001 RSHLGNPELSFYLFITPPKTVLDDHTQTLFQPQLGDRVAPFTLGPSLKRCLGPEQRTRLP
430 440 450 460 470 480
pF1KE6 ------------------------------------------------------------
NP_001 VVGDGGDVDSGRLLFWGPSRGRASPSTGQPPCHPVCRPSSPPSPRPSSGDPSRVKAGHKH
490 500 510 520 530 540
460 470 480 490 500
pF1KE6 -----ANLFPAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPA
::::::::::::::::::::::::::::::::::::::::
NP_001 VGTGRANLFPAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPA
550 560 570 580 590 600
510 520 530 540 550
pF1KE6 PDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
NP_001 PDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
610 620 630 640
>--
initn: 430 init1: 430 opt: 430 Z-score: 283.4 bits: 62.5 E(85289): 4.8e-09
Smith-Waterman score: 430; 100.0% identity (100.0% similar) in 62 aa overlap (492-553:586-647)
470 480 490 500 510 520
pF1KE6 LGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGA
::::::::::::::::::::::::::::::
NP_001 LGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEPAAEEGA
560 570 580 590 600 610
530 540 550
pF1KE6 LVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
::::::::::::::::::::::::::::::::
NP_001 LVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
620 630 640
>>XP_016880531 (OMIM: 606236,606243) PREDICTED: tether c (578 aa)
initn: 3834 init1: 2933 opt: 2953 Z-score: 1855.7 bits: 353.2 E(85289): 1.3e-96
Smith-Waterman score: 3668; 95.3% identity (95.3% similar) in 578 aa overlap (1-553:1-578)
10 20 30 40 50 60
pF1KE6 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
370 380 390 400 410 420
430 440 450
pF1KE6 RSHLGNPELSFYL-------------------------FITPPKTVLDDHTQTLFQANLF
::::::::::::: :::::::::::::::::::::
XP_016 RSHLGNPELSFYLCLSSFGRMDGRGPRCFLTRRCLLSSVITPPKTVLDDHTQTLFQANLF
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE6 PAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEP
490 500 510 520 530 540
520 530 540 550
pF1KE6 AAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
::::::::::::::::::::::::::::::::::::::
XP_016 AAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
550 560 570
>>XP_016880526 (OMIM: 606236,606243) PREDICTED: tether c (645 aa)
initn: 3749 init1: 2933 opt: 2953 Z-score: 1855.0 bits: 353.3 E(85289): 1.4e-96
Smith-Waterman score: 3583; 95.2% identity (95.2% similar) in 566 aa overlap (1-541:1-566)
10 20 30 40 50 60
pF1KE6 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
370 380 390 400 410 420
430 440 450
pF1KE6 RSHLGNPELSFYL-------------------------FITPPKTVLDDHTQTLFQANLF
::::::::::::: :::::::::::::::::::::
XP_016 RSHLGNPELSFYLCLSSFGRMDGRGPRCFLTRRCLLSSVITPPKTVLDDHTQTLFQANLF
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE6 PAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEP
490 500 510 520 530 540
520 530 540 550
pF1KE6 AAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
::::::::::::::::::::::::::
XP_016 AAEEGALVPPEPIPGTAQPVKRSLGKPARGESCQPEVPTPPATGPPPLPAGIKTCASLNA
550 560 570 580 590 600
>>XP_016880525 (OMIM: 606236,606243) PREDICTED: tether c (660 aa)
initn: 3813 init1: 2933 opt: 2953 Z-score: 1854.9 bits: 353.3 E(85289): 1.4e-96
Smith-Waterman score: 3647; 95.0% identity (95.3% similar) in 576 aa overlap (1-551:1-576)
10 20 30 40 50 60
pF1KE6 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPCEYDLKFQRSVLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVRRRLAQLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETVGDLRDFV
370 380 390 400 410 420
430 440 450
pF1KE6 RSHLGNPELSFYL-------------------------FITPPKTVLDDHTQTLFQANLF
::::::::::::: :::::::::::::::::::::
XP_016 RSHLGNPELSFYLCLSSFGRMDGRGPRCFLTRRCLLSSVITPPKTVLDDHTQTLFQANLF
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE6 PAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPSPLPAPDPAPKSEP
490 500 510 520 530 540
520 530 540 550
pF1KE6 AAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
::::::::::::::::::::::::::::::::::..
XP_016 AAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPGTAAGWKPARGESCQPEVPTPPATGP
550 560 570 580 590 600
XP_016 PPLPAGIKTCASLNAFLSCFLQKRAPVVCPGSAGPQCPGLRAWWTMVWAPEEPGGPWCAS
610 620 630 640 650 660
>>NP_001317457 (OMIM: 606236,606243) tether containing U (501 aa)
initn: 3316 init1: 2415 opt: 2435 Z-score: 1533.8 bits: 293.5 E(85289): 1.1e-78
Smith-Waterman score: 3150; 94.6% identity (94.6% similar) in 501 aa overlap (78-553:1-501)
50 60 70 80 90 100
pF1KE6 CEYDLKFQRSVLDLSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDS
::::::::::::::::::::::::::::::
NP_001 MVPASRSREGPENMVRIALQLDDGSRLQDS
10 20 30
110 120 130 140 150 160
pF1KE6 FCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSAT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 IRFVMKCYDPVGKTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRFVMKCYDPVGKTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEH
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 TQEKQSTRAPAAAPFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKS
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
NP_001 TQEKQSTRAPAAAPFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE6 GQDPQQEQEQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQDPQQEQEQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFEL
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE6 TVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFF
280 290 300 310 320 330
410 420 430 440
pF1KE6 RPSETVGDLRDFVRSHLGNPELSFYL-------------------------FITPPKTVL
:::::::::::::::::::::::::: ::::::::
NP_001 RPSETVGDLRDFVRSHLGNPELSFYLCLSSFGRMDGRGPRCFLTRRCLLSSVITPPKTVL
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE6 DDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPS
400 410 420 430 440 450
510 520 530 540 550
pF1KE6 PLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
460 470 480 490 500
>>XP_016880529 (OMIM: 606236,606243) PREDICTED: tether c (583 aa)
initn: 3295 init1: 2415 opt: 2435 Z-score: 1533.0 bits: 293.5 E(85289): 1.2e-78
Smith-Waterman score: 3129; 94.2% identity (94.6% similar) in 499 aa overlap (78-551:1-499)
50 60 70 80 90 100
pF1KE6 CEYDLKFQRSVLDLSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDS
::::::::::::::::::::::::::::::
XP_016 MVPASRSREGPENMVRIALQLDDGSRLQDS
10 20 30
110 120 130 140 150 160
pF1KE6 FCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSAT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 IRFVMKCYDPVGKTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRFVMKCYDPVGKTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEH
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 TQEKQSTRAPAAAPFVPFSGGGQRQGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKS
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 TQEKQSTRAPAAAPFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE6 GQDPQQEQEQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQDPQQEQEQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFEL
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE6 TVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFF
280 290 300 310 320 330
410 420 430 440
pF1KE6 RPSETVGDLRDFVRSHLGNPELSFYL-------------------------FITPPKTVL
:::::::::::::::::::::::::: ::::::::
XP_016 RPSETVGDLRDFVRSHLGNPELSFYLCLSSFGRMDGRGPRCFLTRRCLLSSVITPPKTVL
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE6 DDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDHTQTLFQANLFPAALVHLGAEEPAGVYLEPGLLEHAISPSAADVLVARYMSRAAGSPS
400 410 420 430 440 450
510 520 530 540 550
pF1KE6 PLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPASKR
:::::::::::::::::::::::::::::::::::::::::::::::..
XP_016 PLPAPDPAPKSEPAAEEGALVPPEPIPGTAQPVKRSLGKVPKWLKLPGTAAGWKPARGES
460 470 480 490 500 510
XP_016 CQPEVPTPPATGPPPLPAGIKTCASLNAFLSCFLQKRAPVVCPGSAGPQCPGLRAWWTMV
520 530 540 550 560 570
553 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:09:27 2016 done: Tue Nov 8 13:09:28 2016
Total Scan time: 9.730 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]