Result of FASTA (omim) for
pFN21AE6423
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6423, 465 aa
1>>>pF1KE6423 465 - 465 aa - 465 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0500+/-0.000337; mu= 15.9393+/- 0.021
mean_var=110.2281+/-22.629, 0's: 0 Z-trim(117.9): 83 B-trim: 1657 in 1/57
Lambda= 0.122160
statistics sampled from 30217 (30307) to 30217 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.355), width: 16
Scan time: 6.290
The best scores are: opt bits E(85289)
NP_037453 (OMIM: 614905) sorting nexin-8 [Homo sap ( 465) 3069 551.6 1.7e-156
XP_011513632 (OMIM: 614905) PREDICTED: sorting nex ( 451) 2874 517.2 3.7e-146
XP_011513631 (OMIM: 614905) PREDICTED: sorting nex ( 457) 2871 516.7 5.3e-146
XP_016867573 (OMIM: 614905) PREDICTED: sorting nex ( 412) 2720 490.0 5.1e-138
XP_016867572 (OMIM: 614905) PREDICTED: sorting nex ( 412) 2720 490.0 5.1e-138
XP_011534188 (OMIM: 605952) PREDICTED: sorting nex ( 501) 197 45.4 0.00042
XP_005267072 (OMIM: 605952) PREDICTED: sorting nex ( 588) 197 45.5 0.00047
NP_057308 (OMIM: 605952) sorting nexin-9 [Homo sap ( 595) 197 45.5 0.00047
XP_016856917 (OMIM: 614904) PREDICTED: sorting nex ( 336) 172 40.9 0.0066
XP_006710740 (OMIM: 614904) PREDICTED: sorting nex ( 422) 173 41.1 0.0069
NP_057060 (OMIM: 614904) sorting nexin-7 isoform a ( 451) 173 41.2 0.0072
XP_016856915 (OMIM: 614904) PREDICTED: sorting nex ( 387) 172 40.9 0.0073
XP_011539866 (OMIM: 614904) PREDICTED: sorting nex ( 387) 172 40.9 0.0073
XP_016856914 (OMIM: 614904) PREDICTED: sorting nex ( 387) 172 40.9 0.0073
XP_016856916 (OMIM: 614904) PREDICTED: sorting nex ( 387) 172 40.9 0.0073
XP_006710741 (OMIM: 614904) PREDICTED: sorting nex ( 387) 172 40.9 0.0073
>>NP_037453 (OMIM: 614905) sorting nexin-8 [Homo sapiens (465 aa)
initn: 3069 init1: 3069 opt: 3069 Z-score: 2930.6 bits: 551.6 E(85289): 1.7e-156
Smith-Waterman score: 3069; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465)
10 20 30 40 50 60
pF1KE6 MTGRAMDPLPAAAVGAAAEAEADEEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MTGRAMDPLPAAAVGAAAEAEADEEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PLLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PLLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LHKFPYRMVPALPPKRMLGADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LHKFPYRMVPALPPKRMLGADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLAD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 AQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 AQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVN
370 380 390 400 410 420
430 440 450 460
pF1KE6 SQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
:::::::::::::::::::::::::::::::::::::::::::::
NP_037 SQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
430 440 450 460
>>XP_011513632 (OMIM: 614905) PREDICTED: sorting nexin-8 (451 aa)
initn: 2874 init1: 2874 opt: 2874 Z-score: 2745.1 bits: 517.2 E(85289): 3.7e-146
Smith-Waterman score: 2874; 100.0% identity (100.0% similar) in 435 aa overlap (31-465:17-451)
10 20 30 40 50 60
pF1KE6 MTGRAMDPLPAAAVGAAAEAEADEEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGN
::::::::::::::::::::::::::::::
XP_011 MHPGLPSTLTCSCSLMSDLPTPQAIEPQAIVQQVPAPSRMQMPQGN
10 20 30 40
70 80 90 100 110 120
pF1KE6 PLLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEML
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 LHKFPYRMVPALPPKRMLGADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFPYRMVPALPPKRMLGADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE6 DVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE6 RIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLAD
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE6 KAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAT
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE6 AQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVN
350 360 370 380 390 400
430 440 450 460
pF1KE6 SQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
410 420 430 440 450
>>XP_011513631 (OMIM: 614905) PREDICTED: sorting nexin-8 (457 aa)
initn: 2871 init1: 2871 opt: 2871 Z-score: 2742.1 bits: 516.7 E(85289): 5.3e-146
Smith-Waterman score: 2871; 99.8% identity (100.0% similar) in 435 aa overlap (31-465:23-457)
10 20 30 40 50 60
pF1KE6 MTGRAMDPLPAAAVGAAAEAEADEEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGN
.:::::::::::::::::::::::::::::
XP_011 MKSHVGGQRESQAGPFPRGHLGTDLPTPQAIEPQAIVQQVPAPSRMQMPQGN
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 PLLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEML
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 LHKFPYRMVPALPPKRMLGADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFPYRMVPALPPKRMLGADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 DVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 RIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLAD
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 KAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSAT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 AQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVN
360 370 380 390 400 410
430 440 450 460
pF1KE6 SQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
420 430 440 450
>>XP_016867573 (OMIM: 614905) PREDICTED: sorting nexin-8 (412 aa)
initn: 2720 init1: 2720 opt: 2720 Z-score: 2598.9 bits: 490.0 E(85289): 5.1e-138
Smith-Waterman score: 2720; 100.0% identity (100.0% similar) in 412 aa overlap (54-465:1-412)
30 40 50 60 70 80
pF1KE6 EEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGNPLLLSHTLQELLARDTVQVELIP
::::::::::::::::::::::::::::::
XP_016 MQMPQGNPLLLSHTLQELLARDTVQVELIP
10 20 30
90 100 110 120 130 140
pF1KE6 EKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGADRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGADRE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE6 FIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE6 TRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAI
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE6 GSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE6 LQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREPESVEQLESRIVEQENAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREPESVEQLESRIVEQENAI
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE6 QTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKEMSKVWNDLRPKLSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKEMSKVWNDLRPKLSCL
340 350 360 370 380 390
450 460
pF1KE6 FAGPHSTLTPPCSPPEDGLCPH
::::::::::::::::::::::
XP_016 FAGPHSTLTPPCSPPEDGLCPH
400 410
>>XP_016867572 (OMIM: 614905) PREDICTED: sorting nexin-8 (412 aa)
initn: 2720 init1: 2720 opt: 2720 Z-score: 2598.9 bits: 490.0 E(85289): 5.1e-138
Smith-Waterman score: 2720; 100.0% identity (100.0% similar) in 412 aa overlap (54-465:1-412)
30 40 50 60 70 80
pF1KE6 EEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGNPLLLSHTLQELLARDTVQVELIP
::::::::::::::::::::::::::::::
XP_016 MQMPQGNPLLLSHTLQELLARDTVQVELIP
10 20 30
90 100 110 120 130 140
pF1KE6 EKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGADRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGADRE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE6 FIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE6 TRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAI
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE6 GSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE6 LQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREPESVEQLESRIVEQENAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREPESVEQLESRIVEQENAI
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE6 QTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKEMSKVWNDLRPKLSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKEMSKVWNDLRPKLSCL
340 350 360 370 380 390
450 460
pF1KE6 FAGPHSTLTPPCSPPEDGLCPH
::::::::::::::::::::::
XP_016 FAGPHSTLTPPCSPPEDGLCPH
400 410
>>XP_011534188 (OMIM: 605952) PREDICTED: sorting nexin-9 (501 aa)
initn: 142 init1: 90 opt: 197 Z-score: 194.7 bits: 45.4 E(85289): 0.00042
Smith-Waterman score: 200; 23.4% identity (52.4% similar) in 359 aa overlap (92-441:175-496)
70 80 90 100 110 120
pF1KE6 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
..::... . :: .::. : . : ::
XP_011 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
150 160 170 180 190 200
130 140 150 160 170
pF1KE6 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
:: . .:.:: :.. : ..:::. : . :. ... . :::..::. :.. ::.:
XP_011 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE6 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
. :..:. ::. . . . . : :.. . : . ..: : :
XP_011 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
270 280 290 300 310
240 250 260 270 280 290
pF1KE6 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
:.. .:: :.: : :::. . .. .::..:.. :.
XP_011 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
320 330 340 350
300 310 320 330 340 350
pF1KE6 DKAAQQGKQEENDVVEKLNLFLDLL------QSYKDLCERHEKGVLHKHQRALHKYSLMK
... ::. . ::.. . . . . : ::: : . :... : . .
XP_011 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
360 370 380 390 400 410
360 370 380 390 400 410
pF1KE6 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
.: . .: ... :.:. :.. :.: : . : :. : . .: . .
XP_011 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
420 430 440 450 460 470
420 430 440 450 460
pF1KE6 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
..: ....:.: .. ... :: ::
XP_011 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM
480 490 500
>>XP_005267072 (OMIM: 605952) PREDICTED: sorting nexin-9 (588 aa)
initn: 142 init1: 90 opt: 197 Z-score: 193.8 bits: 45.5 E(85289): 0.00047
Smith-Waterman score: 200; 23.4% identity (52.4% similar) in 359 aa overlap (92-441:262-583)
70 80 90 100 110 120
pF1KE6 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
..::... . :: .::. : . : ::
XP_005 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
240 250 260 270 280 290
130 140 150 160 170
pF1KE6 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
:: . .:.:: :.. : ..:::. : . :. ... . :::..::. :.. ::.:
XP_005 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
300 310 320 330 340 350
180 190 200 210 220 230
pF1KE6 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
. :..:. ::. . . . . : :.. . : . ..: : :
XP_005 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
360 370 380 390 400
240 250 260 270 280 290
pF1KE6 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
:.. .:: :.: : :::. . .. .::..:.. :.
XP_005 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
410 420 430 440
300 310 320 330 340 350
pF1KE6 DKAAQQGKQEENDVVEKLNLFLDLL------QSYKDLCERHEKGVLHKHQRALHKYSLMK
... ::. . ::.. . . . . : ::: : . :... : . .
XP_005 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
450 460 470 480 490 500
360 370 380 390 400 410
pF1KE6 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
.: . .: ... :.:. :.. :.: : . : :. : . .: . .
XP_005 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
510 520 530 540 550
420 430 440 450 460
pF1KE6 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
..: ....:.: .. ... :: ::
XP_005 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM
560 570 580
>>NP_057308 (OMIM: 605952) sorting nexin-9 [Homo sapiens (595 aa)
initn: 142 init1: 90 opt: 197 Z-score: 193.7 bits: 45.5 E(85289): 0.00047
Smith-Waterman score: 200; 23.4% identity (52.4% similar) in 359 aa overlap (92-441:269-590)
70 80 90 100 110 120
pF1KE6 LLLSHTLQELLARDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFQEMLL
..::... . :: .::. : . : ::
NP_057 YGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLL
240 250 260 270 280 290
130 140 150 160 170
pF1KE6 HKFPYRM-VPALPPKRMLGA-DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSG
:: . .:.:: :.. : ..:::. : . :. ... . :::..::. :.. ::.:
NP_057 VKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD
300 310 320 330 340 350
180 190 200 210 220 230
pF1KE6 SDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRA
. :..:. ::. . . . . : :.. . : . ..: : :
NP_057 EKEWKTGKRKAE--RDELAGVMIFSTMEPEAP-DLDL---VEIEQKCEAVGKFTKAMD--
360 370 380 390 400 410
240 250 260 270 280 290
pF1KE6 ERIASRAIDNAADLLIFGKELSAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLA
:.. .:: :.: : :::. . .. .::..:.. :.
NP_057 --------DGVKELLTVGQE--HWKRCTGPLPK-------EYQKIGKALQSLATVFS---
420 430 440 450
300 310 320 330 340 350
pF1KE6 DKAAQQGKQEENDVVEKLNLFLDLL------QSYKDLCERHEKGVLHKHQRALHKYSLMK
... ::. . ::.. . . . . : ::: : . :... : . .
NP_057 -SSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECN--HEYKGFLGCFPDII
460 470 480 490 500
360 370 380 390 400 410
pF1KE6 RQMMSATAQNREPESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHV-YLPLTS
.: . .: ... :.:. :.. :.: : . : :. : . .: . .
NP_057 GTHKGAIEKVKESDKLVAT-SKITLQDK--QNMVKRVSIMSYALQAEMNHFHSNRIYDYN
510 520 530 540 550 560
420 430 440 450 460
pF1KE6 HILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH
..: ....:.: .. ... :: ::
NP_057 SVIRLYLEQQVQFYETIAE---KLRQALSRFPVM
570 580 590
>>XP_016856917 (OMIM: 614904) PREDICTED: sorting nexin-7 (336 aa)
initn: 167 init1: 107 opt: 172 Z-score: 173.2 bits: 40.9 E(85289): 0.0066
Smith-Waterman score: 175; 27.5% identity (58.1% similar) in 160 aa overlap (54-188:1-157)
30 40 50 60 70 80
pF1KE6 EEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGNPLLLSHTLQELLARDTVQVELIP
:.: . .:.. . :. . . .. : :
XP_016 MDMNSFSPMMPTSPLSMI---NQIKFEDEP
10 20
90 100 110 120
pF1KE6 EKKGLFL------KHVE-------YEV----SSQRFKSS---VYRRYNDFVVFQEMLLHK
. : ::. .:: :.. : .: :: : :::.::. .. : .
XP_016 DLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA
30 40 50 60 70 80
130 140 150 160 170
pF1KE6 FPYRMVPALPPKRMLGA-----DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFS
: ..: :: : .. . . .:::.::.::..:.: .: :: .. . .:.::. .
XP_016 HPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQ
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE6 GSDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDR
. ..... :.
XP_016 AWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKIS
150 160 170 180 190 200
>>XP_006710740 (OMIM: 614904) PREDICTED: sorting nexin-7 (422 aa)
initn: 167 init1: 107 opt: 173 Z-score: 172.8 bits: 41.1 E(85289): 0.0069
Smith-Waterman score: 177; 27.8% identity (58.0% similar) in 162 aa overlap (52-188:85-243)
30 40 50 60 70 80
pF1KE6 ADEEADPPASDLPTPQAIEPQAIVQQVPAPSRMQMPQGNPLLLSHTLQELLARDTVQVEL
: :.: . .:.. . :. . . .. :
XP_006 GSSGSSALLQAEVLDLDEDEDDLEVFSKDASLMDMNSFSPMMPTSPLSMI---NQIKFED
60 70 80 90 100 110
90 100 110 120
pF1KE6 IPEKKGLFL------KHVE-------YEV----SSQRFKSS---VYRRYNDFVVFQEMLL
:. : ::. .:: :.. : .: :: : :::.::. .. :
XP_006 EPDLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLE
120 130 140 150 160 170
130 140 150 160 170
pF1KE6 HKFPYRMVPALPPKRMLGA-----DREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLS
. : ..: :: : .. . . .:::.::.::..:.: .: :: .. . .:.::.
XP_006 EAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLT
180 190 200 210 220 230
180 190 200 210 220 230
pF1KE6 FSGSDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLR
.. ..... :.
XP_006 AQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDK
240 250 260 270 280 290
465 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:08:56 2016 done: Tue Nov 8 13:08:57 2016
Total Scan time: 6.290 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]