Result of FASTA (omim) for
pFN21AE6421
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6421, 558 aa
1>>>pF1KE6421 558 - 558 aa - 558 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5641+/-0.000396; mu= 17.6684+/- 0.025
mean_var=77.3282+/-15.834, 0's: 0 Z-trim(113.7): 42 B-trim: 571 in 1/49
Lambda= 0.145850
statistics sampled from 23139 (23164) to 23139 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.272), width: 16
Scan time: 7.490
The best scores are: opt bits E(85289)
NP_057452 (OMIM: 611670) inositol-3-phosphate synt ( 558) 3724 793.4 0
NP_001164409 (OMIM: 611670) inositol-3-phosphate s ( 504) 3114 665.0 1.5e-190
NP_001240318 (OMIM: 611670) inositol-3-phosphate s ( 430) 2891 618.1 1.8e-176
XP_011526361 (OMIM: 611670) PREDICTED: inositol-3- ( 626) 2390 512.8 1.3e-144
>>NP_057452 (OMIM: 611670) inositol-3-phosphate synthase (558 aa)
initn: 3724 init1: 3724 opt: 3724 Z-score: 4234.9 bits: 793.4 E(85289): 0
Smith-Waterman score: 3724; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558)
10 20 30 40 50 60
pF1KE6 MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 VPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 DDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 RQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNG
490 500 510 520 530 540
550
pF1KE6 CTGDANGHLQEEPPMPTT
::::::::::::::::::
NP_057 CTGDANGHLQEEPPMPTT
550
>>NP_001164409 (OMIM: 611670) inositol-3-phosphate synth (504 aa)
initn: 3113 init1: 3113 opt: 3114 Z-score: 3541.9 bits: 665.0 E(85289): 1.5e-190
Smith-Waterman score: 3245; 90.3% identity (90.3% similar) in 558 aa overlap (1-558:1-504)
10 20 30 40 50 60
pF1KE6 MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLG
::::::::::::::::::::::::::::::::::::::::
NP_001 MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLK--------------------
10 20 30 40
70 80 90 100 110 120
pF1KE6 VMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVF
::::::::::::::::::::::::::
NP_001 ----------------------------------EANYYGSLTQAGTVSLGLDAEGQEVF
50 60
130 140 150 160 170 180
pF1KE6 VPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYI
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE6 PEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVIPG
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE6 LNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVFVG
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE6 GDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSNVV
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE6 DDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDS
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE6 LLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNALF
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE6 RQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAATNG
430 440 450 460 470 480
550
pF1KE6 CTGDANGHLQEEPPMPTT
::::::::::::::::::
NP_001 CTGDANGHLQEEPPMPTT
490 500
>>NP_001240318 (OMIM: 611670) inositol-3-phosphate synth (430 aa)
initn: 2891 init1: 2891 opt: 2891 Z-score: 3289.3 bits: 618.1 E(85289): 1.8e-176
Smith-Waterman score: 2891; 100.0% identity (100.0% similar) in 430 aa overlap (129-558:1-430)
100 110 120 130 140 150
pF1KE6 YGSLTQAGTVSLGLDAEGQEVFVPFSAVLPMVAPNDLVFDGWDISSLNLAEAMRRAKVLD
::::::::::::::::::::::::::::::
NP_001 MVAPNDLVFDGWDISSLNLAEAMRRAKVLD
10 20 30
160 170 180 190 200 210
pF1KE6 WGLQEQLWPHMEALRPRPSVYIPEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WGLQEQLWPHMEALRPRPSVYIPEFIAANQSARADNLIPGSRAQQLEQIRRDIRDFRSSA
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE6 GLDKVIVLWTANTERFCEVIPGLNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLDKVIVLWTANTERFCEVIPGLNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNG
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE6 SPQNTLVPGALELAWQHRVFVGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPQNTLVPGALELAWQHRVFVGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNN
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE6 DGENLSAPLQFRSKEVSKSNVVDDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGENLSAPLQFRSKEVSKSNVVDDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDE
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE6 YTSELMLGGTNTLVLHNTCEDSLLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTSELMLGGTNTLVLHNTCEDSLLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLS
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE6 LLSFLFKAPLVPPGSPVVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSFLFKAPLVPPGSPVVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRV
340 350 360 370 380 390
520 530 540 550
pF1KE6 GPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMPTT
::::::::::::::::::::::::::::::::::::::::
NP_001 GPVAATYPMLNKKGPVPAATNGCTGDANGHLQEEPPMPTT
400 410 420 430
>>XP_011526361 (OMIM: 611670) PREDICTED: inositol-3-phos (626 aa)
initn: 2390 init1: 2390 opt: 2390 Z-score: 2717.2 bits: 512.8 E(85289): 1.3e-144
Smith-Waterman score: 3346; 88.5% identity (88.5% similar) in 590 aa overlap (37-558:37-626)
10 20 30 40 50 60
pF1KE6 FFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLGVMLVGW
::::::::::::::::::::::::::::::
XP_011 FFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLGVMLVGW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVFVPFSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVFVPFSAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYIPEFIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPMVAPNDLVFDGWDISSLNLAEAMRRAKVLDWGLQEQLWPHMEALRPRPSVYIPEFIAA
130 140 150 160 170 180
190 200
pF1KE6 NQSARADNLIPGSRAQQ-------------------------------------------
:::::::::::::::::
XP_011 NQSARADNLIPGSRAQQVLSHPASLASCHLFFATWFPLFAPPRESRPHLTPGELSSPGLC
190 200 210 220 230 240
210 220 230
pF1KE6 -------------------------LEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVI
:::::::::::::::::::::::::::::::::::
XP_011 ESESMYNQLPYTLSILPTPSPSNPQLEQIRRDIRDFRSSAGLDKVIVLWTANTERFCEVI
250 260 270 280 290 300
240 250 260 270 280 290
pF1KE6 PGLNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGLNDTAENLLRTIELGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQHRVF
310 320 330 340 350 360
300 310 320 330 340 350
pF1KE6 VGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGENLSAPLQFRSKEVSKSN
370 380 390 400 410 420
360 370 380 390 400 410
pF1KE6 VVDDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVDDMVQSNPVLYTPGEEPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCE
430 440 450 460 470 480
420 430 440 450 460 470
pF1KE6 DSLLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLLAAPIMLDLALLTELCQRVSFCTDMDPEPQTFHPVLSLLSFLFKAPLVPPGSPVVNA
490 500 510 520 530 540
480 490 500 510 520 530
pF1KE6 LFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFRQRSCIENILRACVGLPPQNHMLLEHKMERPGPSLKRVGPVAATYPMLNKKGPVPAAT
550 560 570 580 590 600
540 550
pF1KE6 NGCTGDANGHLQEEPPMPTT
::::::::::::::::::::
XP_011 NGCTGDANGHLQEEPPMPTT
610 620
>--
initn: 232 init1: 232 opt: 232 Z-score: 263.2 bits: 58.7 E(85289): 6.4e-08
Smith-Waterman score: 232; 100.0% identity (100.0% similar) in 36 aa overlap (1-36:1-36)
10 20 30 40 50 60
pF1KE6 MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLG
::::::::::::::::::::::::::::::::::::
XP_011 MEAAAQFFVESPDVVYGPEAIEAQYEYRTTRVSREGGVLKVHPTSTRFTFRTARQVPRLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVF
XP_011 VMLVGWGGNNGSTLTAAVLANRLRLSWPTRSGRKEANYYGSLTQAGTVSLGLDAEGQEVF
70 80 90 100 110 120
558 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:07:46 2016 done: Tue Nov 8 13:07:47 2016
Total Scan time: 7.490 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]