Result of FASTA (ccds) for
pFN21AE6389
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6389, 385 aa
1>>>pF1KE6389 385 - 385 aa - 385 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2367+/-0.000932; mu= 17.0396+/- 0.055
mean_var=68.0327+/-14.333, 0's: 0 Z-trim(105.3): 34 B-trim: 403 in 1/49
Lambda= 0.155495
statistics sampled from 8301 (8327) to 8301 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.256), width: 16
Scan time: 2.510
The best scores are: opt bits E(32554)
CCDS47815.1 SLC18A1 gene_id:6570|Hs108|chr8 ( 472) 2494 568.7 3.8e-162
CCDS6013.1 SLC18A1 gene_id:6570|Hs108|chr8 ( 525) 2494 568.7 4.1e-162
CCDS47814.1 SLC18A1 gene_id:6570|Hs108|chr8 ( 493) 1988 455.2 5.8e-128
CCDS7599.1 SLC18A2 gene_id:6571|Hs108|chr10 ( 514) 1533 353.1 3.2e-97
CCDS7231.1 SLC18A3 gene_id:6572|Hs108|chr10 ( 532) 766 181.1 2.1e-45
CCDS5163.1 SLC18B1 gene_id:116843|Hs108|chr6 ( 456) 283 72.7 7.5e-13
>>CCDS47815.1 SLC18A1 gene_id:6570|Hs108|chr8 (472 aa)
initn: 2494 init1: 2494 opt: 2494 Z-score: 3024.6 bits: 568.7 E(32554): 3.8e-162
Smith-Waterman score: 2494; 99.7% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KE6 MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
310 320 330 340 350 360
370 380
pF1KE6 NKMGRWLCSLIGMLVVGTSLLCLPS
::::::::::::::::::::::.:
CCDS47 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
370 380 390 400 410 420
>>CCDS6013.1 SLC18A1 gene_id:6570|Hs108|chr8 (525 aa)
initn: 2494 init1: 2494 opt: 2494 Z-score: 3023.9 bits: 568.7 E(32554): 4.1e-162
Smith-Waterman score: 2494; 99.7% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KE6 MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
310 320 330 340 350 360
370 380
pF1KE6 NKMGRWLCSLIGMLVVGTSLLCLPS
::::::::::::::::::::::.:
CCDS60 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
370 380 390 400 410 420
>>CCDS47814.1 SLC18A1 gene_id:6570|Hs108|chr8 (493 aa)
initn: 2252 init1: 1966 opt: 1988 Z-score: 2410.8 bits: 455.2 E(32554): 5.8e-128
Smith-Waterman score: 2184; 91.4% identity (91.7% similar) in 384 aa overlap (1-384:1-352)
10 20 30 40 50 60
pF1KE6 MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
::::::: :::::::::::::::::::::
CCDS47 YILVAAG--------------------------------LAFLPASVSYLIGTNLFGVLA
310 320
370 380
pF1KE6 NKMGRWLCSLIGMLVVGTSLLCLPS
::::::::::::::::::::::.:
CCDS47 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
330 340 350 360 370 380
>>CCDS7599.1 SLC18A2 gene_id:6571|Hs108|chr10 (514 aa)
initn: 1544 init1: 1335 opt: 1533 Z-score: 1858.9 bits: 353.1 E(32554): 3.2e-97
Smith-Waterman score: 1533; 62.6% identity (86.1% similar) in 374 aa overlap (11-384:10-376)
10 20 30 40 50 60
pF1KE6 MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
: :.:.: ::.:.: .::.::::::::.::::::.:..::.. :. ...
CCDS75 MALSELALVRWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSI--KHEKNA
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
.. : : : .:..:::...:.:. : .. .. ...::. .:.: ::
CCDS75 TEIQTARPVHTASISDSFQSIFSYYDNSTM-VTGNATRDLT-LHQTATQ--HMVTNA-SA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
..: . : .: ..::.::::::..::..:::.: ::::::: ::.:::: :::.:
CCDS75 VPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
:.:::::..:..:..::.::::::: :::::.::::::::::.::: .:: ::::::.:.
CCDS75 TIMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
::: :::::.::::::.::::.:: :.:::::.:: .::::.:.::: ::::: :::::
CCDS75 LVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
:::.:::::::::::.:.:::.::::::.:::: :::::.::::::.:::::::.::.::
CCDS75 YILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILA
300 310 320 330 340 350
370 380
pF1KE6 NKMGRWLCSLIGMLVVGTSLLCLPS
.:::::::.:.::..::.:.::.:
CCDS75 HKMGRWLCALLGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDL
360 370 380 390 400 410
>>CCDS7231.1 SLC18A3 gene_id:6572|Hs108|chr10 (532 aa)
initn: 864 init1: 510 opt: 766 Z-score: 928.8 bits: 181.1 E(32554): 2.1e-45
Smith-Waterman score: 865; 38.8% identity (67.5% similar) in 379 aa overlap (13-385:25-376)
10 20 30 40
pF1KE6 MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTF
:.: : .:.::::.: :::::::::. :.::::: .
CCDS72 MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 LYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTAS
. :. .: .: .: . : ..: : .:
CCDS72 IA-----------HMRGGGEGP--TRTPE-------------VWEPTLPLPTP-ANASAY
70 80 90
110 120 130 140 150 160
pF1KE6 TIPPPATEAISAHKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHI
: :. . . .. :. : : ...::::::::..::::::. ::. .:..: .
CCDS72 TANTSASPTAAWPAGSALRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDV
100 110 120 130 140 150
170 180 190 200 210 220
pF1KE6 PMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRA
:.. :. .:: :::.:::. :. ::.::.:::.::.:....:..:.:. : .. ::.::
CCDS72 PLLIGLGVMFASTVLFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRA
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE6 MGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESA
.:.::. ...: ::. :::...:::.:: .:::.:: ..:.:. : : . .: ... ..
CCDS72 LGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARAR
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE6 K----GTPLFMLLKDPYILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLP
:::. :. :::: :.::.. :. .:.::::. :: .:: . .:..:.:.::
CCDS72 ANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLP
280 290 300 310 320 330
350 360 370 380
pF1KE6 ASVSYLIGTNLFGVLANKMG--RWLCSLIGMLVVGTSLLCLPS
: : ...:. : :: .. .:: . .:. :.:.: .:.
CCDS72 AFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGASSCIVPACRSFAPLVVSLCGLCFG
340 350 360 370 380 390
CCDS72 IALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSL
400 410 420 430 440 450
>>CCDS5163.1 SLC18B1 gene_id:116843|Hs108|chr6 (456 aa)
initn: 244 init1: 105 opt: 283 Z-score: 344.2 bits: 72.7 E(32554): 7.5e-13
Smith-Waterman score: 283; 26.1% identity (61.0% similar) in 264 aa overlap (137-384:70-322)
110 120 130 140 150 160
pF1KE6 ASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGY
: .:..:. :...::.. : .::
CCDS51 AASVNLGSMMCYSILGPFFPKEAEKKGASNTIIGMIFGCFALFELLASLVFGNYLVHIGA
40 50 60 70 80 90
170 180 190 200 210
pF1KE6 HIPMFAGFVIMFLSTVMFAF-----SGTY--TLLFVARTLQGIGSSFSSVAGLGMLASVY
.. . ::. . :..:. .: .. :..:...... . . .:. ..::...
CCDS51 KFMFVAGMFVSGGVTILFGVLDRVPDGPVFIAMCFLVRVMDAVSFAAAMTASSSILAKAF
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE6 TDDHERGRAMGTALGGL----ALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQL
.. ..:.::.: .:::..: : :. .:. : .::..:. ..:: :..
CCDS51 PNN------VATVLGSLETFSGLGLILGPPVGGFLYQSFGYEVPFIVLGCVVLLMVPLNM
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE6 CILQPSKVSPESAKGTPLFMLLKDPYILVAAGSI--CFANMGVAILEPTLPIWMMQTMCS
:: . .: . :. : : : . .:. ::. .:.::: ..... .
CCDS51 YILPNYESDPGEHSFWKLIALPKVGLIAFVINSLSSCFG-----FLDPTLSLFVLEKFNL
220 230 240 250 260
340 350 360 370 380
pF1KE6 PKWQLGLAFLPASVSYLIGTNLFGVLANK---MGRWLCSLIGMLVVGTSLLCLPS
: .::.:: ..:: :.. :::.:..: . .:: . .....: .: :
CCDS51 PAGYVGLVFLGMALSYAISSPLFGLLSDKRPPLRKWLLVFGNLITAGCYMLLGPVPILHI
270 280 290 300 310 320
CCDS51 KSQLWLLVLILVVSGLSAGMSIIPTFPEILSCAHENGFEEGLSTLGLVSGLFSAMWSIGA
330 340 350 360 370 380
385 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:50:11 2016 done: Tue Nov 8 12:50:11 2016
Total Scan time: 2.510 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]