Result of FASTA (omim) for
pFN21AE6381
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6381, 319 aa
1>>>pF1KE6381 319 - 319 aa - 319 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7286+/-0.000466; mu= 18.6939+/- 0.029
mean_var=63.1283+/-13.482, 0's: 0 Z-trim(108.0): 82 B-trim: 947 in 1/53
Lambda= 0.161422
statistics sampled from 15962 (16044) to 15962 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.541), E-opt: 0.2 (0.188), width: 16
Scan time: 5.100
The best scores are: opt bits E(85289)
NP_001188478 (OMIM: 603878) monocarboxylate transp ( 319) 2126 504.3 1.4e-142
NP_001306149 (OMIM: 603878) monocarboxylate transp ( 257) 1630 388.7 6.8e-108
XP_005271374 (OMIM: 603878) PREDICTED: monocarboxy ( 487) 1172 282.3 1.4e-75
NP_004687 (OMIM: 603878) monocarboxylate transport ( 487) 1172 282.3 1.4e-75
XP_006711096 (OMIM: 603878) PREDICTED: monocarboxy ( 377) 979 237.2 4e-62
NP_001188476 (OMIM: 603878) monocarboxylate transp ( 425) 979 237.3 4.4e-62
NP_001188475 (OMIM: 603878) monocarboxylate transp ( 439) 979 237.3 4.5e-62
NP_001188477 (OMIM: 603878) monocarboxylate transp ( 382) 691 170.2 6.2e-42
XP_016871728 (OMIM: 611910,612018) PREDICTED: mono ( 516) 425 108.3 3.5e-23
XP_016871726 (OMIM: 611910,612018) PREDICTED: mono ( 516) 425 108.3 3.5e-23
NP_998771 (OMIM: 611910,612018) monocarboxylate tr ( 516) 425 108.3 3.5e-23
XP_016871727 (OMIM: 611910,612018) PREDICTED: mono ( 516) 425 108.3 3.5e-23
XP_011523763 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 367 94.8 4.1e-19
XP_016880781 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 367 94.8 4.1e-19
XP_016880780 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 367 94.8 4.1e-19
NP_001167637 (OMIM: 603880) monocarboxylate transp ( 523) 367 94.8 4.1e-19
NP_004685 (OMIM: 603880) monocarboxylate transport ( 523) 367 94.8 4.1e-19
XP_005257846 (OMIM: 603880) PREDICTED: monocarboxy ( 527) 367 94.8 4.1e-19
NP_004722 (OMIM: 603654) monocarboxylate transport ( 478) 353 91.5 3.7e-18
XP_005269288 (OMIM: 603654) PREDICTED: monocarboxy ( 478) 353 91.5 3.7e-18
NP_001257551 (OMIM: 603654) monocarboxylate transp ( 478) 353 91.5 3.7e-18
NP_001257552 (OMIM: 603654) monocarboxylate transp ( 478) 353 91.5 3.7e-18
NP_919274 (OMIM: 614242) monocarboxylate transport ( 509) 337 87.8 5.1e-17
XP_016871373 (OMIM: 614242) PREDICTED: monocarboxy ( 509) 337 87.8 5.1e-17
NP_001310910 (OMIM: 614242) monocarboxylate transp ( 509) 337 87.8 5.1e-17
XP_016871372 (OMIM: 614242) PREDICTED: monocarboxy ( 551) 337 87.8 5.4e-17
XP_016884174 (OMIM: 610409) PREDICTED: monocarboxy ( 504) 328 85.7 2.2e-16
NP_037488 (OMIM: 610409) monocarboxylate transport ( 504) 328 85.7 2.2e-16
XP_011523764 (OMIM: 603879) PREDICTED: monocarboxy ( 532) 325 85.0 3.6e-16
XP_005257847 (OMIM: 603879) PREDICTED: monocarboxy ( 545) 325 85.0 3.7e-16
NP_001159968 (OMIM: 245340,600682,610021,616095) m ( 500) 322 84.3 5.6e-16
XP_011540328 (OMIM: 245340,600682,610021,616095) P ( 500) 322 84.3 5.6e-16
XP_011540329 (OMIM: 245340,600682,610021,616095) P ( 500) 322 84.3 5.6e-16
NP_003042 (OMIM: 245340,600682,610021,616095) mono ( 500) 322 84.3 5.6e-16
NP_699188 (OMIM: 615765) monocarboxylate transport ( 471) 319 83.6 8.8e-16
XP_016879770 (OMIM: 615765) PREDICTED: monocarboxy ( 511) 319 83.6 9.3e-16
XP_005256545 (OMIM: 615765) PREDICTED: monocarboxy ( 566) 319 83.7 1e-15
NP_001258694 (OMIM: 603879) monocarboxylate transp ( 505) 318 83.4 1.1e-15
NP_004686 (OMIM: 603879) monocarboxylate transport ( 505) 318 83.4 1.1e-15
NP_001035888 (OMIM: 603877) monocarboxylate transp ( 465) 312 82.0 2.7e-15
NP_001193879 (OMIM: 603877) monocarboxylate transp ( 465) 312 82.0 2.7e-15
XP_011521909 (OMIM: 603877) PREDICTED: monocarboxy ( 465) 312 82.0 2.7e-15
NP_001193880 (OMIM: 603877) monocarboxylate transp ( 465) 312 82.0 2.7e-15
NP_001035887 (OMIM: 603877) monocarboxylate transp ( 465) 312 82.0 2.7e-15
NP_004198 (OMIM: 603877) monocarboxylate transport ( 465) 312 82.0 2.7e-15
NP_001193881 (OMIM: 603877) monocarboxylate transp ( 465) 312 82.0 2.7e-15
XP_011533724 (OMIM: 607550) PREDICTED: monocarboxy ( 321) 309 81.1 3.3e-15
XP_006715392 (OMIM: 607550) PREDICTED: monocarboxy ( 325) 309 81.1 3.3e-15
NP_061063 (OMIM: 607550) monocarboxylate transport ( 515) 309 81.3 4.7e-15
NP_001310909 (OMIM: 614242) monocarboxylate transp ( 422) 272 72.6 1.6e-12
>>NP_001188478 (OMIM: 603878) monocarboxylate transporte (319 aa)
initn: 2126 init1: 2126 opt: 2126 Z-score: 2681.0 bits: 504.3 E(85289): 1.4e-142
Smith-Waterman score: 2126; 100.0% identity (100.0% similar) in 319 aa overlap (1-319:1-319)
10 20 30 40 50 60
pF1KE6 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGILET
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
250 260 270 280 290 300
310
pF1KE6 SSVSFFFVPLAERWKNSLT
:::::::::::::::::::
NP_001 SSVSFFFVPLAERWKNSLT
310
>>NP_001306149 (OMIM: 603878) monocarboxylate transporte (257 aa)
initn: 1630 init1: 1630 opt: 1630 Z-score: 2058.0 bits: 388.7 E(85289): 6.8e-108
Smith-Waterman score: 1630; 99.2% identity (99.2% similar) in 249 aa overlap (71-319:9-257)
50 60 70 80 90 100
pF1KE6 FAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGG
: :::::::::::::::::::::::::::
NP_001 MGMDDCDSFFPGPLVAIICDILGEKTTSILGAFVVTGG
10 20 30
110 120 130 140 150 160
pF1KE6 YLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 LAPFTKFLIDLYDWTGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPFTKFLIDLYDWTGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATT
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 FPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWL
160 170 180 190 200 210
290 300 310
pF1KE6 YDYTQTYNGSFYFSGICYLLSSVSFFFVPLAERWKNSLT
:::::::::::::::::::::::::::::::::::::::
NP_001 YDYTQTYNGSFYFSGICYLLSSVSFFFVPLAERWKNSLT
220 230 240 250
>>XP_005271374 (OMIM: 603878) PREDICTED: monocarboxylate (487 aa)
initn: 1193 init1: 1167 opt: 1172 Z-score: 1477.7 bits: 282.3 E(85289): 1.4e-75
Smith-Waterman score: 1172; 90.5% identity (93.5% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KE6 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGILET
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_005 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
. : . : .. .. :
XP_005 FGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDS
190 200 210 220 230 240
>--
initn: 972 init1: 972 opt: 979 Z-score: 1234.8 bits: 237.3 E(85289): 4.8e-62
Smith-Waterman score: 979; 89.9% identity (92.9% similar) in 169 aa overlap (158-319:319-487)
130 140 150 160 170 180
pF1KE6 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFL-IDLYDWT------GILET
:: :. .: : ::..: . :::::
XP_005 QLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILET
290 300 310 320 330 340
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
350 360 370 380 390 400
250 260 270 280 290 300
pF1KE6 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
410 420 430 440 450 460
310
pF1KE6 SSVSFFFVPLAERWKNSLT
:::::::::::::::::::
XP_005 SSVSFFFVPLAERWKNSLT
470 480
>>NP_004687 (OMIM: 603878) monocarboxylate transporter 5 (487 aa)
initn: 1193 init1: 1167 opt: 1172 Z-score: 1477.7 bits: 282.3 E(85289): 1.4e-75
Smith-Waterman score: 1172; 90.5% identity (93.5% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KE6 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGILET
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_004 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
. : . : .. .. :
NP_004 FGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDS
190 200 210 220 230 240
>--
initn: 972 init1: 972 opt: 979 Z-score: 1234.8 bits: 237.3 E(85289): 4.8e-62
Smith-Waterman score: 979; 89.9% identity (92.9% similar) in 169 aa overlap (158-319:319-487)
130 140 150 160 170 180
pF1KE6 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFL-IDLYDWT------GILET
:: :. .: : ::..: . :::::
NP_004 QLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILET
290 300 310 320 330 340
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
350 360 370 380 390 400
250 260 270 280 290 300
pF1KE6 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
410 420 430 440 450 460
310
pF1KE6 SSVSFFFVPLAERWKNSLT
:::::::::::::::::::
NP_004 SSVSFFFVPLAERWKNSLT
470 480
>>XP_006711096 (OMIM: 603878) PREDICTED: monocarboxylate (377 aa)
initn: 972 init1: 972 opt: 979 Z-score: 1236.4 bits: 237.2 E(85289): 4e-62
Smith-Waterman score: 979; 89.9% identity (92.9% similar) in 169 aa overlap (158-319:209-377)
130 140 150 160 170 180
pF1KE6 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFL-IDLYDWT------GILET
:: :. .: : ::..: . :::::
XP_006 QLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILET
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE6 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
300 310 320 330 340 350
310
pF1KE6 SSVSFFFVPLAERWKNSLT
:::::::::::::::::::
XP_006 SSVSFFFVPLAERWKNSLT
360 370
>--
initn: 423 init1: 361 opt: 368 Z-score: 467.4 bits: 94.9 E(85289): 2.7e-19
Smith-Waterman score: 368; 74.1% identity (84.0% similar) in 81 aa overlap (119-199:9-89)
90 100 110 120 130 140
pF1KE6 TSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALST
..::::::::::::::::::::::::::::
XP_006 MGMDDCDSFFPGLGSAFLYQVAAVVTTKYFKKRLALST
10 20 30
150 160 170 180 190 200
pF1KE6 AIARSGMGLTFLLAPFTKFLIDLYDWTGILETVSQIISGWVADQNWIKKYHYHKSYLILC
:::::::::::::::::::::::::::: : . : . : .. .. :
XP_006 AIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE6 GITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGM
XP_006 KDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNR
100 110 120 130 140 150
>>NP_001188476 (OMIM: 603878) monocarboxylate transporte (425 aa)
initn: 972 init1: 972 opt: 979 Z-score: 1235.6 bits: 237.3 E(85289): 4.4e-62
Smith-Waterman score: 979; 89.9% identity (92.9% similar) in 169 aa overlap (158-319:257-425)
130 140 150 160 170 180
pF1KE6 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFL-IDLYDWT------GILET
:: :. .: : ::..: . :::::
NP_001 QLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILET
230 240 250 260 270 280
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
290 300 310 320 330 340
250 260 270 280 290 300
pF1KE6 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
350 360 370 380 390 400
310
pF1KE6 SSVSFFFVPLAERWKNSLT
:::::::::::::::::::
NP_001 SSVSFFFVPLAERWKNSLT
410 420
>--
initn: 715 init1: 666 opt: 676 Z-score: 854.3 bits: 166.7 E(85289): 7.6e-41
Smith-Waterman score: 676; 83.7% identity (88.4% similar) in 129 aa overlap (71-199:9-137)
50 60 70 80 90 100
pF1KE6 FAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGG
: :::::::::::::::::::::::::::
NP_001 MGMDDCDSFFPGPLVAIICDILGEKTTSILGAFVVTGG
10 20 30
110 120 130 140 150 160
pF1KE6 YLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 LAPFTKFLIDLYDWTGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATT
:::::::::::::::: : . : . : .. .. :
NP_001 LAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGP
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 FPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWL
NP_001 EAHATETHCHETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESD
160 170 180 190 200 210
>>NP_001188475 (OMIM: 603878) monocarboxylate transporte (439 aa)
initn: 1467 init1: 972 opt: 979 Z-score: 1235.5 bits: 237.3 E(85289): 4.5e-62
Smith-Waterman score: 979; 89.9% identity (92.9% similar) in 169 aa overlap (158-319:271-439)
130 140 150 160 170 180
pF1KE6 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFL-IDLYDWT------GILET
:: :. .: : ::..: . :::::
NP_001 QLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILET
250 260 270 280 290 300
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
310 320 330 340 350 360
250 260 270 280 290 300
pF1KE6 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLL
370 380 390 400 410 420
310
pF1KE6 SSVSFFFVPLAERWKNSLT
:::::::::::::::::::
NP_001 SSVSFFFVPLAERWKNSLT
430
>--
initn: 895 init1: 509 opt: 513 Z-score: 648.9 bits: 128.8 E(85289): 2.1e-29
Smith-Waterman score: 751; 66.3% identity (69.3% similar) in 199 aa overlap (1-199:1-151)
10 20 30 40 50 60
pF1KE6 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL
::::::::::::::
NP_001 WIGSIMSSLRFCAG----------------------------------------------
70
130 140 150 160 170 180
pF1KE6 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGILET
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 --LGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
. : . : .. .. :
NP_001 FGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDS
140 150 160 170 180 190
>>NP_001188477 (OMIM: 603878) monocarboxylate transporte (382 aa)
initn: 677 init1: 677 opt: 691 Z-score: 873.8 bits: 170.2 E(85289): 6.2e-42
Smith-Waterman score: 691; 72.0% identity (82.3% similar) in 164 aa overlap (158-308:209-372)
130 140 150 160 170 180
pF1KE6 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFL-IDLYDWT------GILET
:: :. .: : ::..: . :::::
NP_001 QLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILET
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE6 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLA
240 250 260 270 280 290
250 260 270 280 290
pF1KE6 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTY----NGSFYFS-G
::::::::::::::::::::::::::::::::::::: . .. : .. .: .
NP_001 LILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAEIIPSFQAGYMIIPRHTMALSTS
300 310 320 330 340 350
300 310
pF1KE6 ICYLLSSVSF-FFVPLAERWKNSLT
. : .::..: ::.
NP_001 LAYAISSLQFPFFLYHWPKDGKTV
360 370 380
>--
initn: 423 init1: 361 opt: 368 Z-score: 467.3 bits: 94.9 E(85289): 2.7e-19
Smith-Waterman score: 368; 74.1% identity (84.0% similar) in 81 aa overlap (119-199:9-89)
90 100 110 120 130 140
pF1KE6 TSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALST
..::::::::::::::::::::::::::::
NP_001 MGMDDCDSFFPGLGSAFLYQVAAVVTTKYFKKRLALST
10 20 30
150 160 170 180 190 200
pF1KE6 AIARSGMGLTFLLAPFTKFLIDLYDWTGILETVSQIISGWVADQNWIKKYHYHKSYLILC
:::::::::::::::::::::::::::: : . : . : .. .. :
NP_001 AIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE6 GITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGM
NP_001 KDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNR
100 110 120 130 140 150
>>XP_016871728 (OMIM: 611910,612018) PREDICTED: monocarb (516 aa)
initn: 603 init1: 359 opt: 425 Z-score: 537.2 bits: 108.3 E(85289): 3.5e-23
Smith-Waterman score: 425; 40.0% identity (70.9% similar) in 175 aa overlap (16-189:44-214)
10 20 30 40
pF1KE6 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFF
::::::::: :::.. . ..:. ..:::
XP_016 IITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFF
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE6 VVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISS
: :: : : .:: ::.. . . .:: ... . :. .. .::..... : ..::
XP_016 VEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSS
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE6 WATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGL-TFLLAPF
.:::. : .:.:.: ::: :. :. : ... :::..: ::. .:: :: :. ::.:::
XP_016 FATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPV
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE6 TKFLIDLYDWTGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLL
...::. ..: : : :..:.:
XP_016 VQLLIEQFSWRGAL----LILGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDI
200 210 220 230 240
>--
initn: 195 init1: 195 opt: 274 Z-score: 347.2 bits: 73.1 E(85289): 1.3e-12
Smith-Waterman score: 274; 26.5% identity (59.4% similar) in 219 aa overlap (102-317:258-469)
80 90 100 110 120 130
pF1KE6 CAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQV
: . :: . :. . : : :. .
XP_016 TLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLA
230 240 250 260 270 280
140 150 160 170 180 190
pF1KE6 AAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGILETVSQIISGWVAD
..:. : . : . . ..:.. : : :.. :... ...: ::..:
XP_016 VSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAF------LMSILGVIDIIGNITFGWLTD
290 300 310 320 330 340
200 210 220 230 240
pF1KE6 QNWIKKYHYHKSYLILCGITNLLA---PLATTFPLLMTYTICFAIFAGGYLALILPVLVD
. .:.:.: ::. :. .: :. ..:::. .. :. : :.:..:: : ..
XP_016 RRCLKNYQY-VCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTE
350 360 370 380 390 400
250 260 270 280 290 300
pF1KE6 LCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFV
. ..... ::.. :. .. : .::::: : : : .:...: . :. ...::: . :.
XP_016 IVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFA
410 420 430 440 450 460
310
pF1KE6 PLAERWKNSLT
: .: ...
XP_016 RLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
470 480 490 500 510
>>XP_016871726 (OMIM: 611910,612018) PREDICTED: monocarb (516 aa)
initn: 603 init1: 359 opt: 425 Z-score: 537.2 bits: 108.3 E(85289): 3.5e-23
Smith-Waterman score: 425; 40.0% identity (70.9% similar) in 175 aa overlap (16-189:44-214)
10 20 30 40
pF1KE6 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFF
::::::::: :::.. . ..:. ..:::
XP_016 IITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFF
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE6 VVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISS
: :: : : .:: ::.. . . .:: ... . :. .. .::..... : ..::
XP_016 VEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSS
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE6 WATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGL-TFLLAPF
.:::. : .:.:.: ::: :. :. : ... :::..: ::. .:: :: :. ::.:::
XP_016 FATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPV
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE6 TKFLIDLYDWTGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLL
...::. ..: : : :..:.:
XP_016 VQLLIEQFSWRGAL----LILGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDI
200 210 220 230 240
>--
initn: 195 init1: 195 opt: 274 Z-score: 347.2 bits: 73.1 E(85289): 1.3e-12
Smith-Waterman score: 274; 26.5% identity (59.4% similar) in 219 aa overlap (102-317:258-469)
80 90 100 110 120 130
pF1KE6 CAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQV
: . :: . :. . : : :. .
XP_016 TLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLA
230 240 250 260 270 280
140 150 160 170 180 190
pF1KE6 AAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGILETVSQIISGWVAD
..:. : . : . . ..:.. : : :.. :... ...: ::..:
XP_016 VSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAF------LMSILGVIDIIGNITFGWLTD
290 300 310 320 330 340
200 210 220 230 240
pF1KE6 QNWIKKYHYHKSYLILCGITNLLA---PLATTFPLLMTYTICFAIFAGGYLALILPVLVD
. .:.:.: ::. :. .: :. ..:::. .. :. : :.:..:: : ..
XP_016 RRCLKNYQY-VCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTE
350 360 370 380 390 400
250 260 270 280 290 300
pF1KE6 LCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFV
. ..... ::.. :. .. : .::::: : : : .:...: . :. ...::: . :.
XP_016 IVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFA
410 420 430 440 450 460
310
pF1KE6 PLAERWKNSLT
: .: ...
XP_016 RLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT
470 480 490 500 510
319 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:45:27 2016 done: Tue Nov 8 12:45:28 2016
Total Scan time: 5.100 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]