Result of FASTA (omim) for
pFN21AE6371
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6371, 423 aa
1>>>pF1KE6371 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4887+/-0.000431; mu= 16.1988+/- 0.027
mean_var=79.5320+/-16.775, 0's: 0 Z-trim(112.0): 311 B-trim: 662 in 1/53
Lambda= 0.143815
statistics sampled from 20400 (20746) to 20400 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.243), width: 16
Scan time: 6.570
The best scores are: opt bits E(85289)
NP_054777 (OMIM: 610399) transmembrane protease se ( 423) 2891 609.9 3.8e-174
XP_011530198 (OMIM: 610399) PREDICTED: transmembra ( 345) 2368 501.3 1.5e-141
NP_001107859 (OMIM: 611704) transmembrane protease ( 418) 1277 275.0 2.4e-73
NP_872412 (OMIM: 611704) transmembrane protease se ( 421) 1266 272.7 1.2e-72
NP_004253 (OMIM: 605369) transmembrane protease se ( 418) 1153 249.3 1.4e-65
XP_005265767 (OMIM: 605369) PREDICTED: transmembra ( 301) 929 202.7 1e-51
XP_016864340 (OMIM: 605369) PREDICTED: transmembra ( 234) 900 196.6 5.4e-50
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 749 165.7 3.9e-40
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 749 165.7 3.9e-40
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 693 153.9 7.8e-37
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 692 153.7 1e-36
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 692 153.7 1.1e-36
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 692 153.7 1.1e-36
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 681 151.3 3.4e-36
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 681 151.4 4.4e-36
NP_001275679 (OMIM: 606751) transmembrane protease ( 413) 679 150.9 5.4e-36
NP_001275680 (OMIM: 606751) transmembrane protease ( 448) 679 151.0 5.8e-36
NP_110397 (OMIM: 606751) transmembrane protease se ( 457) 679 151.0 5.9e-36
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 677 150.5 6.8e-36
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 677 150.6 7.8e-36
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 677 150.6 8.3e-36
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 677 150.6 8.3e-36
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 677 150.6 8.8e-36
NP_068813 (OMIM: 606797) suppressor of tumorigenic ( 855) 661 147.4 1.3e-34
NP_001277025 (OMIM: 606565) transmembrane protease ( 290) 645 143.8 5.4e-34
XP_011526284 (OMIM: 610477) PREDICTED: transmembra ( 562) 648 144.6 6e-34
NP_001167023 (OMIM: 606565) transmembrane protease ( 397) 645 143.9 7e-34
XP_011526282 (OMIM: 610477) PREDICTED: transmembra ( 690) 648 144.7 7e-34
NP_002763 (OMIM: 226200,606635) enteropeptidase pr (1019) 650 145.2 7.2e-34
NP_001277023 (OMIM: 606565) transmembrane protease ( 412) 645 143.9 7.2e-34
XP_011527961 (OMIM: 226200,606635) PREDICTED: ente (1034) 650 145.2 7.2e-34
XP_011527960 (OMIM: 226200,606635) PREDICTED: ente (1037) 650 145.2 7.3e-34
XP_011527959 (OMIM: 226200,606635) PREDICTED: ente (1049) 650 145.2 7.3e-34
XP_011527958 (OMIM: 226200,606635) PREDICTED: ente (1064) 650 145.2 7.4e-34
XP_011527956 (OMIM: 226200,606635) PREDICTED: ente (1064) 650 145.2 7.4e-34
XP_011527957 (OMIM: 226200,606635) PREDICTED: ente (1064) 650 145.2 7.4e-34
NP_001077416 (OMIM: 606565) transmembrane protease ( 432) 645 143.9 7.5e-34
NP_001167022 (OMIM: 606565) transmembrane protease ( 435) 645 143.9 7.5e-34
NP_063947 (OMIM: 606565) transmembrane protease se ( 437) 645 143.9 7.5e-34
NP_892018 (OMIM: 610477) transmembrane protease se (1059) 648 144.8 9.8e-34
XP_011526280 (OMIM: 610477) PREDICTED: transmembra (1093) 648 144.8 1e-33
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454) 633 141.4 4.4e-33
XP_011541204 (OMIM: 606565) PREDICTED: transmembra ( 456) 633 141.4 4.4e-33
XP_011541203 (OMIM: 606565) PREDICTED: transmembra ( 489) 633 141.5 4.6e-33
XP_005271671 (OMIM: 606565) PREDICTED: transmembra ( 492) 633 141.5 4.6e-33
XP_005271670 (OMIM: 606565) PREDICTED: transmembra ( 494) 633 141.5 4.7e-33
NP_001182058 (OMIM: 613517,613858) serine protease ( 603) 618 138.4 4.7e-32
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 613 137.2 5.9e-32
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 611 136.8 8.3e-32
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 611 136.8 8.3e-32
>>NP_054777 (OMIM: 610399) transmembrane protease serine (423 aa)
initn: 2891 init1: 2891 opt: 2891 Z-score: 3247.4 bits: 609.9 E(85289): 3.8e-174
Smith-Waterman score: 2891; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KE6 MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 RRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 ARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 ARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 ASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 ASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 SLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK
370 380 390 400 410 420
pF1KE6 TGI
:::
NP_054 TGI
>>XP_011530198 (OMIM: 610399) PREDICTED: transmembrane p (345 aa)
initn: 2368 init1: 2368 opt: 2368 Z-score: 2662.2 bits: 501.3 E(85289): 1.5e-141
Smith-Waterman score: 2368; 100.0% identity (100.0% similar) in 345 aa overlap (79-423:1-345)
50 60 70 80 90 100
pF1KE6 KTYNYYSTLSFTTDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKF
::::::::::::::::::::::::::::::
XP_011 MSQRLESMVKNAFYKSPLREEFVKSQVIKF
10 20 30
110 120 130 140 150 160
pF1KE6 SQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 ETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 SAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE6 YTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE6 NDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYT
280 290 300 310 320 330
410 420
pF1KE6 RVTALRDWITSKTGI
:::::::::::::::
XP_011 RVTALRDWITSKTGI
340
>>NP_001107859 (OMIM: 611704) transmembrane protease ser (418 aa)
initn: 1093 init1: 974 opt: 1277 Z-score: 1437.6 bits: 275.0 E(85289): 2.4e-73
Smith-Waterman score: 1277; 42.8% identity (75.4% similar) in 423 aa overlap (1-423:1-418)
10 20 30 40 50 60
pF1KE6 MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFT
:::: .:.: .::.:...: .:: :.:: ::: ::.. ..::: : :......
NP_001 MMYRTVGFGTRSR-NLKPWMIAVLIVLSLTVVAVTIGLLVHFLVFDQKKEY-YHGSFKIL
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 TDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHML
.. .::. . .. .. . :..: . : : .....:.::.... .. :: . ..
NP_001 DPQINNNFGQSNTYQLKDLRETTENLVDEIFIDSAWKKNYIKNQVVRLTPEEDGVKVDVI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 LICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGT
.. .: :::. . .: .: .:..:... . : .. ::... .... . .. ::
NP_001 MVFQFPSTEQRAVREKKIQSILNQKIRNLRALP-INASSVQVNAMSSSTGELTVQASCG-
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 RRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNP
.: :. . ::..:. . .. ::::::::.:. :.::::::. ::::.::::: ::::
NP_001 KRVVPLNVN-RIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKYKNP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 ARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPD
.::.:::. :.: :::..::.:.::::. ...:::.....:: : ... ....:::.
NP_001 HQWTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 ASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAG
:: :::. .. .:::::: : ::: ::.:.: .:. .:..::.:.. : : :.:::
NP_001 ASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAG
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 SLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK
.:: :::.::::::::. : .: ::: :::::::.:.. .::::::.:: :.::.::
NP_001 YMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASK
360 370 380 390 400 410
pF1KE6 TGI
:::
NP_001 TGI
>>NP_872412 (OMIM: 611704) transmembrane protease serine (421 aa)
initn: 1187 init1: 974 opt: 1266 Z-score: 1425.3 bits: 272.7 E(85289): 1.2e-72
Smith-Waterman score: 1266; 43.0% identity (75.1% similar) in 426 aa overlap (1-423:1-421)
10 20 30 40 50 60
pF1KE6 MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFT
:::: .:.: .::.:...: .:: :.:: ::: ::.. ..::: : :......
NP_872 MMYRTVGFGTRSR-NLKPWMIAVLIVLSLTVVAVTIGLLVHFLVFDQKKEY-YHGSFKIL
10 20 30 40 50
70 80 90 100 110
pF1KE6 TDKLYAEFGREAS---NNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLA
.. .::. . ... : .. : :.: . : : .....:.::.... .. :: .
NP_872 DPQINNNFGQSNTYQLKDLRETTENLVSQVDEIFIDSAWKKNYIKNQVVRLTPEEDGVKV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 HMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHC
.... .: :::. . .: .: .:..:... . : .. ::... .... . ..
NP_872 DVIMVFQFPSTEQRAVREKKIQSILNQKIRNLRALP-INASSVQVNAMSSSTGELTVQAS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTY
:: .: :. . ::..:. . .. ::::::::.:. :.::::::. ::::.::::: :
NP_872 CG-KRVVPLNVN-RIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 KNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVC
::: .::.:::. :.: :::..::.:.::::. ...:::.....:: : ... ....:
NP_872 KNPHQWTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQIC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 LPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRML
::.:: :::. .. .:::::: : ::: ::.:.: .:. .:..::.:.. : : :.
NP_872 LPEASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 CAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI
::: .:: :::.::::::::. : .: ::: :::::::.:.. .::::::.:: :.::
NP_872 CAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWI
360 370 380 390 400 410
420
pF1KE6 TSKTGI
.:::::
NP_872 ASKTGI
420
>>NP_004253 (OMIM: 605369) transmembrane protease serine (418 aa)
initn: 900 init1: 900 opt: 1153 Z-score: 1298.6 bits: 249.3 E(85289): 1.4e-65
Smith-Waterman score: 1153; 38.9% identity (73.0% similar) in 422 aa overlap (2-423:1-418)
10 20 30 40 50 60
pF1KE6 MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFT
:::: : . .: .:.:. ... ....::: :.: :... ..:: .: : :....
NP_004 MYRPARVTSTSRFL-NPYVVCFIVVAGVVILAVTIALLVYFLAFDQK-SYFYRSSFQLL
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 TDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHML
. . .... :.... .: :.::.. ..: .: ::..:....: :. :. :: : ..
NP_004 NVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 LICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGT
. .: ... .. . .. ::.. :... : ...: :..: ... . ..: . ::.
NP_004 MKFQFTRNNNGASMKSRIESVLRQMLNNS-GNLEINP-STEITSLTDQAAANWLINECGA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 RRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNP
. . ::.::::.::: ::::.::. ...:.::..::: :...::::: . .::
NP_004 GPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 ARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPD
: :. :.. :.. .: :..:..:: .:. ::.:..: . : .:. .: ::::
NP_004 RDWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 ASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAG
:. .. ::.. .:::.:: . :.. .:::.:: .:. .:: :..:: :: :::::
NP_004 ATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAG
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 SLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK
.: .::::::::::::. :.: .:...:::::::.:. :.:::::::::: ::: ..
NP_004 VPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQ
360 370 380 390 400 410
pF1KE6 TGI
:::
NP_004 TGI
>>XP_005265767 (OMIM: 605369) PREDICTED: transmembrane p (301 aa)
initn: 900 init1: 900 opt: 929 Z-score: 1049.4 bits: 202.7 E(85289): 1e-51
Smith-Waterman score: 929; 43.0% identity (74.0% similar) in 300 aa overlap (124-423:4-301)
100 110 120 130 140 150
pF1KE6 SPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPP
.: ... .. . .. ::.. :... :
XP_005 MKFQFTRNNNGASMKSRIESVLRQMLNNS-GNL
10 20 30
160 170 180 190 200 210
pF1KE6 KVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDG
...: :..: ... . ..: . ::. . . ::.::::.::: ::::.::. ..
XP_005 EINP-STEITSLTDQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNN
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE6 SHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPS
.:.::..::: :...::::: . .:: : :. :.. :.. .: :..:..:: .
XP_005 AHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGISTTFPKLRMRVRNILIHNNYKSAT
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE6 HDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQ
:. ::.:..: . : .:. .: :::: :. .. ::.. .:::.:: . :.. .:::.:
XP_005 HENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQ
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE6 VTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVS
: .:. .:: :..:: :: ::::: .: .::::::::::::. :.: .:...::::
XP_005 VRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVS
220 230 240 250 260 270
400 410 420
pF1KE6 WGDECAKPNKPGVYTRVTALRDWITSKTGI
:::.:. :.:::::::::: ::: ..:::
XP_005 WGDQCGLPDKPGVYTRVTAYLDWIRQQTGI
280 290 300
>>XP_016864340 (OMIM: 605369) PREDICTED: transmembrane p (234 aa)
initn: 900 init1: 900 opt: 900 Z-score: 1018.5 bits: 196.6 E(85289): 5.4e-50
Smith-Waterman score: 900; 50.4% identity (78.2% similar) in 234 aa overlap (190-423:1-234)
160 170 180 190 200 210
pF1KE6 VKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGA
.::.::::.::: ::::.::. ...:.::.
XP_016 MRILGGTEAEEGSWPWQVSLRLNNAHHCGG
10 20 30
220 230 240 250 260 270
pF1KE6 TLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDIS
.::: :...::::: . .:: : :. :.. :.. .: :..:..:: .:. ::.
XP_016 SLINNMWILTAAHCFRSNSNPRDWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIA
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE6 LAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDA
:..: . : .:. .: :::: :. .. ::.. .:::.:: . :.. .:::.:: .:.
XP_016 LVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISN
100 110 120 130 140 150
340 350 360 370 380 390
pF1KE6 TTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECA
.:: :..:: :: ::::: .: .::::::::::::. :.: .:...:::::::.:.
XP_016 DVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCG
160 170 180 190 200 210
400 410 420
pF1KE6 KPNKPGVYTRVTALRDWITSKTGI
:.:::::::::: ::: ..:::
XP_016 LPDKPGVYTRVTAYLDWIRQQTGI
220 230
>>NP_001275930 (OMIM: 206200,609862) transmembrane prote (802 aa)
initn: 737 init1: 303 opt: 749 Z-score: 841.6 bits: 165.7 E(85289): 3.9e-40
Smith-Waterman score: 749; 45.8% identity (68.7% similar) in 249 aa overlap (176-417:556-797)
150 160 170 180 190 200
pF1KE6 LQDAVGPPKVDPHSVKIKKINKTETDSYLNHC-CGTRRSKTLGQSLRIVGGTEVEEGEWP
:: :: . : : :::::. :::::
NP_001 TFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQ-----GPSSRIVGGAVSSEGEWP
530 540 550 560 570 580
210 220 230 240 250
pF1KE6 WQASLQWDGSHRCGATLINATWLVSAAHCFT--TYKNPARWTASFGVTIK----PSKMKR
:::::: : : ::..:: :...::::: .. . . ::. .: . . :....
NP_001 WQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSF
590 600 610 620 630 640
260 270 280 290 300 310
pF1KE6 GLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGA
. :...: ... :::::..: .:. :: . ::. :::: :. :.:: ..::.::
NP_001 KVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGA
650 660 670 680 690 700
320 330 340 350 360 370
pF1KE6 LKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLV
:.. : .: :....: :: :.: .: .:::::::: .:: ::::::::::::
NP_001 LREGGPISNALQKVDVQLIPQDLCSE--VYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
710 720 730 740 750
380 390 400 410 420
pF1KE6 SSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTGI
. :.:::.:::: :..:: :::::.:.. .::
NP_001 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
760 770 780 790 800
>>NP_705837 (OMIM: 206200,609862) transmembrane protease (811 aa)
initn: 737 init1: 303 opt: 749 Z-score: 841.5 bits: 165.7 E(85289): 3.9e-40
Smith-Waterman score: 749; 45.8% identity (68.7% similar) in 249 aa overlap (176-417:565-806)
150 160 170 180 190 200
pF1KE6 LQDAVGPPKVDPHSVKIKKINKTETDSYLNHC-CGTRRSKTLGQSLRIVGGTEVEEGEWP
:: :: . : : :::::. :::::
NP_705 TFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQ-----GPSSRIVGGAVSSEGEWP
540 550 560 570 580
210 220 230 240 250
pF1KE6 WQASLQWDGSHRCGATLINATWLVSAAHCFT--TYKNPARWTASFGVTIK----PSKMKR
:::::: : : ::..:: :...::::: .. . . ::. .: . . :....
NP_705 WQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSF
590 600 610 620 630 640
260 270 280 290 300 310
pF1KE6 GLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGA
. :...: ... :::::..: .:. :: . ::. :::: :. :.:: ..::.::
NP_705 KVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGA
650 660 670 680 690 700
320 330 340 350 360 370
pF1KE6 LKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLV
:.. : .: :....: :: :.: .: .:::::::: .:: ::::::::::::
NP_705 LREGGPISNALQKVDVQLIPQDLCSE--VYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
710 720 730 740 750 760
380 390 400 410 420
pF1KE6 SSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTGI
. :.:::.:::: :..:: :::::.:.. .::
NP_705 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
770 780 790 800 810
>>NP_001243246 (OMIM: 605511) transmembrane protease ser (453 aa)
initn: 660 init1: 322 opt: 693 Z-score: 782.3 bits: 153.9 E(85289): 7.8e-37
Smith-Waterman score: 693; 41.7% identity (65.5% similar) in 264 aa overlap (158-417:186-443)
130 140 150 160 170 180
pF1KE6 TEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHC--CGTRRSKT
::: ... . : .: :: ::
NP_001 LRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTL-QCTACGHRR---
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE6 LGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTA
: : :::::. ..::::::::..: : ::...:. :...:::: : ::
NP_001 -GYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTI
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE6 SFG-VTIKPSKMKRGL-RRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASY
. : :.. . : ..:. : ::: ::.: .:..:. ... .. ::::..
NP_001 QVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEE
280 290 300 310 320 330
310 320 330 340 350 360
pF1KE6 EFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLE
.: : : ...:.:: .. : .. : .: : ::. ::. ..:. :.: ::::: :
NP_001 NFPDGKVCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLT
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE6 GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTGI
: .:.:::::::::: .. : .: :.: .:.: ::. ::::::::::.. :::
NP_001 GGVDSCQGDSGGPLVCQE-RRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMER
400 410 420 430 440
NP_001 DLKT
450
423 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:40:30 2016 done: Tue Nov 8 12:40:31 2016
Total Scan time: 6.570 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]