Result of FASTA (omim) for
pFN21AE6361
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6361, 348 aa
1>>>pF1KE6361 348 - 348 aa - 348 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3536+/-0.000327; mu= 16.4618+/- 0.020
mean_var=67.6592+/-13.385, 0's: 0 Z-trim(115.8): 317 B-trim: 0 in 0/53
Lambda= 0.155923
statistics sampled from 26117 (26436) to 26117 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.31), width: 16
Scan time: 5.670
The best scores are: opt bits E(85289)
NP_002763 (OMIM: 226200,606635) enteropeptidase pr (1019) 663 158.1 8e-38
XP_011527961 (OMIM: 226200,606635) PREDICTED: ente (1034) 663 158.1 8.1e-38
XP_011527960 (OMIM: 226200,606635) PREDICTED: ente (1037) 663 158.1 8.1e-38
XP_011527959 (OMIM: 226200,606635) PREDICTED: ente (1049) 663 158.1 8.2e-38
XP_011527958 (OMIM: 226200,606635) PREDICTED: ente (1064) 663 158.1 8.3e-38
XP_011527956 (OMIM: 226200,606635) PREDICTED: ente (1064) 663 158.1 8.3e-38
XP_011527957 (OMIM: 226200,606635) PREDICTED: ente (1064) 663 158.1 8.3e-38
XP_011526284 (OMIM: 610477) PREDICTED: transmembra ( 562) 650 155.0 3.7e-37
XP_011526282 (OMIM: 610477) PREDICTED: transmembra ( 690) 650 155.0 4.4e-37
NP_001088 (OMIM: 102480) acrosin precursor [Homo s ( 421) 640 152.7 1.4e-36
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 623 148.8 1.8e-35
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 623 148.9 2.1e-35
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 623 148.9 2.2e-35
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 623 148.9 2.2e-35
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 623 148.9 2.4e-35
XP_006723244 (OMIM: 142440) PREDICTED: serine prot ( 417) 619 147.9 3.6e-35
XP_016882220 (OMIM: 142440) PREDICTED: serine prot ( 417) 619 147.9 3.6e-35
NP_892028 (OMIM: 142440) serine protease hepsin pr ( 417) 619 147.9 3.6e-35
XP_005258895 (OMIM: 142440) PREDICTED: serine prot ( 417) 619 147.9 3.6e-35
NP_002142 (OMIM: 142440) serine protease hepsin pr ( 417) 619 147.9 3.6e-35
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 617 147.5 5.1e-35
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 617 147.5 5.1e-35
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 617 147.6 7e-35
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 617 147.6 7.1e-35
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 617 147.6 7.1e-35
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 614 147.0 1.4e-34
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 614 147.0 1.4e-34
XP_016882221 (OMIM: 142440) PREDICTED: serine prot ( 393) 609 145.7 1.6e-34
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 608 145.5 2.1e-34
NP_892018 (OMIM: 610477) transmembrane protease se (1059) 605 145.0 7e-34
XP_011526280 (OMIM: 610477) PREDICTED: transmembra (1093) 605 145.0 7.1e-34
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 598 143.2 7.8e-34
NP_068813 (OMIM: 606797) suppressor of tumorigenic ( 855) 603 144.5 8e-34
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 598 143.2 1e-33
NP_001277025 (OMIM: 606565) transmembrane protease ( 290) 591 141.6 2.1e-33
NP_001167023 (OMIM: 606565) transmembrane protease ( 397) 591 141.6 2.7e-33
NP_001277023 (OMIM: 606565) transmembrane protease ( 412) 591 141.6 2.8e-33
NP_001077416 (OMIM: 606565) transmembrane protease ( 432) 591 141.7 2.9e-33
NP_001167022 (OMIM: 606565) transmembrane protease ( 435) 591 141.7 2.9e-33
NP_063947 (OMIM: 606565) transmembrane protease se ( 437) 591 141.7 3e-33
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 585 140.4 8.9e-33
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 585 140.4 9.3e-33
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 582 139.7 1.5e-32
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454) 579 139.0 2e-32
XP_011541204 (OMIM: 606565) PREDICTED: transmembra ( 456) 579 139.0 2e-32
XP_011541203 (OMIM: 606565) PREDICTED: transmembra ( 489) 579 139.0 2.1e-32
XP_005271671 (OMIM: 606565) PREDICTED: transmembra ( 492) 579 139.0 2.1e-32
XP_005271670 (OMIM: 606565) PREDICTED: transmembra ( 494) 579 139.0 2.1e-32
NP_114154 (OMIM: 608018) serine protease 27 isofor ( 290) 573 137.5 3.5e-32
NP_001265514 (OMIM: 605236,614595) atrial natriure ( 938) 573 137.8 9.2e-32
>>NP_002763 (OMIM: 226200,606635) enteropeptidase precur (1019 aa)
initn: 559 init1: 137 opt: 663 Z-score: 800.1 bits: 158.1 E(85289): 8e-38
Smith-Waterman score: 663; 40.6% identity (67.0% similar) in 261 aa overlap (62-319:770-1019)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTA-PLKDVLQGSRIIGGTEAQAGAWP
:.:: .:. .:.::..:. ::::
NP_002 KLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDIT--PKIVGGSNAKEGAWP
740 750 760 770 780 790
100 110 120 130 140
pF1KE6 WVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTAVIGTNNIHG-RYPH
:::.: ::.: ::..:: :...::::. . .: :::..: . . :.
NP_002 WVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQ
800 810 820 830 840 850
150 160 170 180 190 200
pF1KE6 TKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFI
: : :.:.:.. . ::::..::. : :.::::::::: . :.. . .: :
NP_002 TVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEEN-QVFPPGRNCSI
860 870 880 890 900 910
210 220 230 240 250 260
pF1KE6 SGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDS
.::: . .:...::::.:.: .: : :... .: : .::: :.:..:.:.:::
NP_002 AGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM-ICAGYEEGGIDSCQGDS
920 930 940 950 960 970
270 280 290 300 310 320
pF1KE6 GGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
:::::: : .:.:. :.::.:. :. . :::: : . .:. . :.:
NP_002 GGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI-QSFLH
980 990 1000 1010
330 340
pF1KE6 NILRGQILIALCFVILLATT
>>XP_011527961 (OMIM: 226200,606635) PREDICTED: enterope (1034 aa)
initn: 559 init1: 137 opt: 663 Z-score: 800.0 bits: 158.1 E(85289): 8.1e-38
Smith-Waterman score: 663; 40.6% identity (67.0% similar) in 261 aa overlap (62-319:785-1034)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTA-PLKDVLQGSRIIGGTEAQAGAWP
:.:: .:. .:.::..:. ::::
XP_011 KLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDIT--PKIVGGSNAKEGAWP
760 770 780 790 800 810
100 110 120 130 140
pF1KE6 WVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTAVIGTNNIHG-RYPH
:::.: ::.: ::..:: :...::::. . .: :::..: . . :.
XP_011 WVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQ
820 830 840 850 860
150 160 170 180 190 200
pF1KE6 TKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFI
: : :.:.:.. . ::::..::. : :.::::::::: . :.. . .: :
XP_011 TVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEEN-QVFPPGRNCSI
870 880 890 900 910 920
210 220 230 240 250 260
pF1KE6 SGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDS
.::: . .:...::::.:.: .: : :... .: : .::: :.:..:.:.:::
XP_011 AGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM-ICAGYEEGGIDSCQGDS
930 940 950 960 970 980
270 280 290 300 310 320
pF1KE6 GGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
:::::: : .:.:. :.::.:. :. . :::: : . .:. . :.:
XP_011 GGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI-QSFLH
990 1000 1010 1020 1030
330 340
pF1KE6 NILRGQILIALCFVILLATT
>>XP_011527960 (OMIM: 226200,606635) PREDICTED: enterope (1037 aa)
initn: 559 init1: 137 opt: 663 Z-score: 800.0 bits: 158.1 E(85289): 8.1e-38
Smith-Waterman score: 663; 40.6% identity (67.0% similar) in 261 aa overlap (62-319:788-1037)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTA-PLKDVLQGSRIIGGTEAQAGAWP
:.:: .:. .:.::..:. ::::
XP_011 KLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDIT--PKIVGGSNAKEGAWP
760 770 780 790 800 810
100 110 120 130 140
pF1KE6 WVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTAVIGTNNIHG-RYPH
:::.: ::.: ::..:: :...::::. . .: :::..: . . :.
XP_011 WVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQ
820 830 840 850 860 870
150 160 170 180 190 200
pF1KE6 TKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFI
: : :.:.:.. . ::::..::. : :.::::::::: . :.. . .: :
XP_011 TVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEEN-QVFPPGRNCSI
880 890 900 910 920 930
210 220 230 240 250 260
pF1KE6 SGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDS
.::: . .:...::::.:.: .: : :... .: : .::: :.:..:.:.:::
XP_011 AGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM-ICAGYEEGGIDSCQGDS
940 950 960 970 980
270 280 290 300 310 320
pF1KE6 GGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
:::::: : .:.:. :.::.:. :. . :::: : . .:. . :.:
XP_011 GGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI-QSFLH
990 1000 1010 1020 1030
330 340
pF1KE6 NILRGQILIALCFVILLATT
>>XP_011527959 (OMIM: 226200,606635) PREDICTED: enterope (1049 aa)
initn: 559 init1: 137 opt: 663 Z-score: 799.9 bits: 158.1 E(85289): 8.2e-38
Smith-Waterman score: 663; 40.6% identity (67.0% similar) in 261 aa overlap (62-319:800-1049)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTA-PLKDVLQGSRIIGGTEAQAGAWP
:.:: .:. .:.::..:. ::::
XP_011 KLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDIT--PKIVGGSNAKEGAWP
770 780 790 800 810 820
100 110 120 130 140
pF1KE6 WVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTAVIGTNNIHG-RYPH
:::.: ::.: ::..:: :...::::. . .: :::..: . . :.
XP_011 WVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQ
830 840 850 860 870 880
150 160 170 180 190 200
pF1KE6 TKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFI
: : :.:.:.. . ::::..::. : :.::::::::: . :.. . .: :
XP_011 TVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEEN-QVFPPGRNCSI
890 900 910 920 930 940
210 220 230 240 250 260
pF1KE6 SGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDS
.::: . .:...::::.:.: .: : :... .: : .::: :.:..:.:.:::
XP_011 AGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM-ICAGYEEGGIDSCQGDS
950 960 970 980 990 1000
270 280 290 300 310 320
pF1KE6 GGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
:::::: : .:.:. :.::.:. :. . :::: : . .:. . :.:
XP_011 GGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI-QSFLH
1010 1020 1030 1040
330 340
pF1KE6 NILRGQILIALCFVILLATT
>>XP_011527958 (OMIM: 226200,606635) PREDICTED: enterope (1064 aa)
initn: 559 init1: 137 opt: 663 Z-score: 799.8 bits: 158.1 E(85289): 8.3e-38
Smith-Waterman score: 663; 40.6% identity (67.0% similar) in 261 aa overlap (62-319:815-1064)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTA-PLKDVLQGSRIIGGTEAQAGAWP
:.:: .:. .:.::..:. ::::
XP_011 KLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDIT--PKIVGGSNAKEGAWP
790 800 810 820 830 840
100 110 120 130 140
pF1KE6 WVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTAVIGTNNIHG-RYPH
:::.: ::.: ::..:: :...::::. . .: :::..: . . :.
XP_011 WVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQ
850 860 870 880 890
150 160 170 180 190 200
pF1KE6 TKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFI
: : :.:.:.. . ::::..::. : :.::::::::: . :.. . .: :
XP_011 TVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEEN-QVFPPGRNCSI
900 910 920 930 940 950
210 220 230 240 250 260
pF1KE6 SGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDS
.::: . .:...::::.:.: .: : :... .: : .::: :.:..:.:.:::
XP_011 AGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM-ICAGYEEGGIDSCQGDS
960 970 980 990 1000 1010
270 280 290 300 310 320
pF1KE6 GGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
:::::: : .:.:. :.::.:. :. . :::: : . .:. . :.:
XP_011 GGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI-QSFLH
1020 1030 1040 1050 1060
330 340
pF1KE6 NILRGQILIALCFVILLATT
>>XP_011527956 (OMIM: 226200,606635) PREDICTED: enterope (1064 aa)
initn: 559 init1: 137 opt: 663 Z-score: 799.8 bits: 158.1 E(85289): 8.3e-38
Smith-Waterman score: 663; 40.6% identity (67.0% similar) in 261 aa overlap (62-319:815-1064)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTA-PLKDVLQGSRIIGGTEAQAGAWP
:.:: .:. .:.::..:. ::::
XP_011 KLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDIT--PKIVGGSNAKEGAWP
790 800 810 820 830 840
100 110 120 130 140
pF1KE6 WVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTAVIGTNNIHG-RYPH
:::.: ::.: ::..:: :...::::. . .: :::..: . . :.
XP_011 WVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQ
850 860 870 880 890
150 160 170 180 190 200
pF1KE6 TKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFI
: : :.:.:.. . ::::..::. : :.::::::::: . :.. . .: :
XP_011 TVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEEN-QVFPPGRNCSI
900 910 920 930 940 950
210 220 230 240 250 260
pF1KE6 SGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDS
.::: . .:...::::.:.: .: : :... .: : .::: :.:..:.:.:::
XP_011 AGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM-ICAGYEEGGIDSCQGDS
960 970 980 990 1000 1010
270 280 290 300 310 320
pF1KE6 GGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
:::::: : .:.:. :.::.:. :. . :::: : . .:. . :.:
XP_011 GGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI-QSFLH
1020 1030 1040 1050 1060
330 340
pF1KE6 NILRGQILIALCFVILLATT
>>XP_011527957 (OMIM: 226200,606635) PREDICTED: enterope (1064 aa)
initn: 559 init1: 137 opt: 663 Z-score: 799.8 bits: 158.1 E(85289): 8.3e-38
Smith-Waterman score: 663; 40.6% identity (67.0% similar) in 261 aa overlap (62-319:815-1064)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTA-PLKDVLQGSRIIGGTEAQAGAWP
:.:: .:. .:.::..:. ::::
XP_011 KLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDIT--PKIVGGSNAKEGAWP
790 800 810 820 830 840
100 110 120 130 140
pF1KE6 WVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTAVIGTNNIHG-RYPH
:::.: ::.: ::..:: :...::::. . .: :::..: . . :.
XP_011 WVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQ
850 860 870 880 890
150 160 170 180 190 200
pF1KE6 TKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFI
: : :.:.:.. . ::::..::. : :.::::::::: . :.. . .: :
XP_011 TVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEEN-QVFPPGRNCSI
900 910 920 930 940 950
210 220 230 240 250 260
pF1KE6 SGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDS
.::: . .:...::::.:.: .: : :... .: : .::: :.:..:.:.:::
XP_011 AGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM-ICAGYEEGGIDSCQGDS
960 970 980 990 1000 1010
270 280 290 300 310 320
pF1KE6 GGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
:::::: : .:.:. :.::.:. :. . :::: : . .:. . :.:
XP_011 GGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI-QSFLH
1020 1030 1040 1050 1060
330 340
pF1KE6 NILRGQILIALCFVILLATT
>>XP_011526284 (OMIM: 610477) PREDICTED: transmembrane p (562 aa)
initn: 573 init1: 145 opt: 650 Z-score: 788.1 bits: 155.0 E(85289): 3.7e-37
Smith-Waterman score: 650; 36.8% identity (60.2% similar) in 299 aa overlap (24-316:276-559)
10 20 30 40 50
pF1KE6 MRLGLLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRR
.:.. :. . .:: :. .: .. : .
XP_011 SPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRV--TGQPANSTLSAVSTTARGQT
250 260 270 280 290 300
60 70 80 90 100
pF1KE6 ----RREGGAHAK--DCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVC
:. .:.. ::: :: .::.::. : : ::: ::: .. . : :
XP_011 PFPDAPEATTHTQLPDCGLAP----AALTRIVGGSAAGRGEWPWQVSLWLRRRE---HRC
310 320 330 340 350
110 120 130 140 150 160
pF1KE6 GGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILES
:..:: :::.:.:::: .:: .:.: .:: . : . ... : :: . : .
XP_011 GAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERV--ARIYKHPFYNLYT
360 370 380 390 400 410
170 180 190 200 210 220
pF1KE6 YVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDA
:.::..: :: . ..::::: . . :: :.: :.::: ..: :. . :: :
XP_011 LDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDG-TRCVITGWGSVREGGSMARQLQKA
420 430 440 450 460 470
230 240 250 260 270 280
pF1KE6 EVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGI
:. .:.. : .: : : . .::: .:. :.: ::.:::: : : :. . :.
XP_011 AVRLLSEQTC--RRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPS-GRWVLTGV
480 490 500 510 520 530
290 300 310 320 330 340
pF1KE6 TSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVILLAT
::.:.:::: ::::: . . :. .:
XP_011 TSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE
540 550 560
>--
initn: 398 init1: 139 opt: 524 Z-score: 635.0 bits: 126.6 E(85289): 1.3e-28
Smith-Waterman score: 524; 37.2% identity (62.0% similar) in 242 aa overlap (76-315:5-236)
50 60 70 80 90 100
pF1KE6 AVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVH
.:..:: : .: :: ::: : : :
XP_011 MEKPTRVVGGFGAASGEVPWQVSL--KEGS--RH
10 20 30
110 120 130 140 150 160
pF1KE6 VCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFIL
::.:.: .::.:.:::: . .. . : .:: .. : :: .. ...:: .
XP_011 FCGATVVGDRWLLSAAHCFNHTKVEQV-RAHLGTASLLGLGGSPVKIGLRRVVLHPLYNP
40 50 60 70 80
170 180 190 200 210 220
pF1KE6 ESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATN--I
:.:...: . . .: ::::.:::. . : . . ::.::::: :.: ::::. .
XP_011 GILDFDLAVLELASPLAFNKYIQPVCLPLAI-QKFPVGRKCMISGWGNTQE-GNATKPEL
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE6 LQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFF
:: : : :... :. ... . . .::: .: :.:.::::::: : :.
XP_011 LQKASVGIIDQKTCSVLYNFS--LTDRMICAGFLEGKVDSCQGDSGGPLACE-EAPGVFY
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE6 VMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVI
. ::.:.: ::.. :::: . . :. :
XP_011 LAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAG
210 220 230 240 250 260
pF1KE6 LLATT
XP_011 LTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAP
270 280 290 300 310 320
>>XP_011526282 (OMIM: 610477) PREDICTED: transmembrane p (690 aa)
initn: 432 init1: 145 opt: 650 Z-score: 786.8 bits: 155.0 E(85289): 4.4e-37
Smith-Waterman score: 650; 36.8% identity (60.2% similar) in 299 aa overlap (24-316:404-687)
10 20 30 40 50
pF1KE6 MRLGLLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRR
.:.. :. . .:: :. .: .. : .
XP_011 SPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRV--TGQPANSTLSAVSTTARGQT
380 390 400 410 420 430
60 70 80 90 100
pF1KE6 ----RREGGAHAK--DCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVC
:. .:.. ::: :: .::.::. : : ::: ::: .. . : :
XP_011 PFPDAPEATTHTQLPDCGLAP----AALTRIVGGSAAGRGEWPWQVSLWLRRRE---HRC
440 450 460 470 480
110 120 130 140 150 160
pF1KE6 GGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILES
:..:: :::.:.:::: .:: .:.: .:: . : . ... : :: . : .
XP_011 GAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERV--ARIYKHPFYNLYT
490 500 510 520 530 540
170 180 190 200 210 220
pF1KE6 YVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDA
:.::..: :: . ..::::: . . :: :.: :.::: ..: :. . :: :
XP_011 LDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDG-TRCVITGWGSVREGGSMARQLQKA
550 560 570 580 590 600
230 240 250 260 270 280
pF1KE6 EVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGI
:. .:.. : .: : : . .::: .:. :.: ::.:::: : : :. . :.
XP_011 AVRLLSEQTC--RRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPS-GRWVLTGV
610 620 630 640 650
290 300 310 320 330 340
pF1KE6 TSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVILLAT
::.:.:::: ::::: . . :. .:
XP_011 TSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE
660 670 680 690
>--
initn: 291 init1: 124 opt: 541 Z-score: 654.3 bits: 130.5 E(85289): 1.1e-29
Smith-Waterman score: 541; 36.6% identity (61.9% similar) in 257 aa overlap (62-315:121-364)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPW
..::. : . . .:..:: : .: ::
XP_011 SPESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPAME--KPTRVVGGFGAASGEVPW
100 110 120 130 140
100 110 120 130 140 150
pF1KE6 VVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKK
::: : : : ::.:.: .::.:.:::: . .. . : .:: .. : :
XP_011 QVSL--KEGSR--HFCGATVVGDRWLLSAAHCFNHTKVEQV-RAHLGTASLLGLGGSPVK
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE6 IKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGW
: .. ...:: . :.:...: . . .: ::::.:::. . : . . ::.::::
XP_011 IGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAI-QKFPVGRKCMISGW
210 220 230 240 250 260
220 230 240 250 260
pF1KE6 GRTKEEGNATN--ILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSG
: :.: ::::. .:: : : :... :. ... . . .::: .: :.:.::::
XP_011 GNTQE-GNATKPELLQKASVGIIDQKTCSVLYNFS--LTDRMICAGFLEGKVDSCQGDSG
270 280 290 300 310
270 280 290 300 310 320
pF1KE6 GPLMCY-LPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
::: : : :.. ::.:.: ::.. :::: . . :. :
XP_011 GPLACEEAPGV--FYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPS
320 330 340 350 360 370
330 340
pF1KE6 NILRGQILIALCFVILLATT
XP_011 TTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAP
380 390 400 410 420 430
>--
initn: 218 init1: 124 opt: 222 Z-score: 266.5 bits: 58.8 E(85289): 4.2e-08
Smith-Waterman score: 222; 47.8% identity (65.2% similar) in 69 aa overlap (253-321:3-70)
230 240 250 260 270 280
pF1KE6 ILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRF
::: :: :.:.:::::::.: : ::
XP_011 MVCAGYLDGKVDSCQGDSGGPLVCEEPS-GRF
10 20 30
290 300 310 320 330 340
pF1KE6 FVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFV
:. ::.:.: ::.. :::: . . :. : .::
XP_011 FLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTS
40 50 60 70 80 90
pF1KE6 ILLATT
XP_011 PESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPAMEKPTRVVGGFGAASGEVPWQVS
100 110 120 130 140 150
>>NP_001088 (OMIM: 102480) acrosin precursor [Homo sapie (421 aa)
initn: 607 init1: 269 opt: 640 Z-score: 777.9 bits: 152.7 E(85289): 1.4e-36
Smith-Waterman score: 640; 39.4% identity (62.5% similar) in 259 aa overlap (64-313:29-285)
40 50 60 70 80 90
pF1KE6 SPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVV
:: .. : ::.:: :: :::::.:
NP_001 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMV
10 20 30 40 50
100 110 120 130 140 150
pF1KE6 SLQI-KYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKI
:::: :. :.:::.:. ::::::::: .. : :.:...: : ..: .
NP_001 SLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEI--TYGNNKPV
60 70 80 90 100 110
160 170 180 190 200
pF1KE6 K-------IKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTK
: .. :::: .. . ::::: .. . . .: : ::: . :. .
NP_001 KAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQS
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE6 CFISGWGRTKEEG-NATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTC
:...::: .:.. ..::..:.: :. ..::: . :.: . :. ::: : .:::
NP_001 CWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTC
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE6 RGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQG
.::::::::: . . . :.::::.: ::.: ::.: . : .:.
NP_001 QGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRM
240 250 260 270 280 290
330 340
pF1KE6 ILTINILRGQILIALCFVILLATT
NP_001 IQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPP
300 310 320 330 340 350
348 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:27:56 2016 done: Tue Nov 8 12:27:57 2016
Total Scan time: 5.670 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]