Result of FASTA (ccds) for
pFN21AE6356
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6356, 321 aa
1>>>pF1KE6356 321 - 321 aa - 321 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3643+/-0.000614; mu= 16.7037+/- 0.037
mean_var=81.8906+/-16.201, 0's: 0 Z-trim(114.1): 172 B-trim: 2 in 1/51
Lambda= 0.141729
statistics sampled from 14495 (14671) to 14495 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.451), width: 16
Scan time: 2.300
The best scores are: opt bits E(32554)
CCDS10430.1 TPSG1 gene_id:25823|Hs108|chr16 ( 321) 2278 474.7 4.3e-134
CCDS10431.1 TPSAB1 gene_id:7177|Hs108|chr16 ( 275) 817 175.9 3.2e-44
CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 ( 317) 778 168.0 9.1e-42
CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 563) 717 155.7 8e-38
CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 532) 704 153.0 4.8e-37
CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 567) 704 153.0 5.1e-37
CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 802) 699 152.1 1.3e-36
CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 811) 699 152.1 1.4e-36
CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 ( 638) 687 149.6 6.2e-36
CCDS5279.1 PLG gene_id:5340|Hs108|chr6 ( 810) 672 146.6 6.2e-35
CCDS74669.1 PRSS56 gene_id:646960|Hs108|chr2 ( 603) 669 145.9 7.6e-35
CCDS47145.1 PRSS48 gene_id:345062|Hs108|chr4 ( 328) 660 143.8 1.7e-34
CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 413) 651 142.1 7.3e-34
CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 448) 651 142.1 7.8e-34
CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 457) 651 142.1 7.9e-34
CCDS1563.1 PRSS38 gene_id:339501|Hs108|chr1 ( 326) 648 141.4 9.3e-34
CCDS13686.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 454) 647 141.3 1.4e-33
CCDS58790.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 453) 646 141.1 1.6e-33
CCDS3521.1 TMPRSS11B gene_id:132724|Hs108|chr4 ( 416) 645 140.9 1.7e-33
CCDS76482.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 290) 642 140.1 2e-33
CCDS43129.2 TMPRSS7 gene_id:344805|Hs108|chr3 ( 717) 646 141.3 2.3e-33
CCDS53717.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 397) 642 140.2 2.5e-33
CCDS3518.1 TMPRSS11D gene_id:9407|Hs108|chr4 ( 418) 642 140.3 2.6e-33
CCDS44743.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 432) 642 140.3 2.7e-33
CCDS53716.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 435) 642 140.3 2.7e-33
CCDS31684.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 437) 642 140.3 2.7e-33
CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 492) 639 139.7 4.6e-33
CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 529) 639 139.7 4.8e-33
CCDS12088.1 TMPRSS9 gene_id:360200|Hs108|chr19 (1059) 637 139.6 1.1e-32
CCDS10432.1 TPSD1 gene_id:23430|Hs108|chr16 ( 242) 622 136.0 3e-32
CCDS47065.1 TMPRSS11A gene_id:339967|Hs108|chr4 ( 418) 617 135.1 9.1e-32
CCDS3519.1 TMPRSS11A gene_id:339967|Hs108|chr4 ( 421) 617 135.1 9.2e-32
CCDS33993.1 TMPRSS11E gene_id:28983|Hs108|chr4 ( 423) 613 134.3 1.6e-31
CCDS3847.1 F11 gene_id:2160|Hs108|chr4 ( 625) 615 134.9 1.6e-31
CCDS157.1 CELA2A gene_id:63036|Hs108|chr1 ( 269) 576 126.6 2.2e-29
CCDS10852.1 CTRL gene_id:1506|Hs108|chr16 ( 264) 569 125.2 5.8e-29
CCDS3520.1 TMPRSS11F gene_id:389208|Hs108|chr4 ( 438) 570 125.5 7.4e-29
CCDS32490.1 CTRB1 gene_id:1504|Hs108|chr16 ( 263) 567 124.8 7.7e-29
CCDS75122.1 CORIN gene_id:10699|Hs108|chr4 ( 938) 568 125.4 1.7e-28
CCDS3477.1 CORIN gene_id:10699|Hs108|chr4 (1042) 568 125.4 1.9e-28
CCDS10476.1 PRSS27 gene_id:83886|Hs108|chr16 ( 290) 560 123.4 2.2e-28
CCDS46816.1 PRSS42 gene_id:339906|Hs108|chr3 ( 293) 558 123.0 3e-28
CCDS32489.1 CTRB2 gene_id:440387|Hs108|chr16 ( 263) 556 122.5 3.6e-28
CCDS10478.1 PRSS21 gene_id:10942|Hs108|chr16 ( 314) 556 122.6 4.2e-28
CCDS5976.1 PRSS55 gene_id:203074|Hs108|chr8 ( 352) 550 121.4 1.1e-27
CCDS58452.1 PRSS36 gene_id:146547|Hs108|chr16 ( 752) 553 122.3 1.2e-27
CCDS58453.1 PRSS36 gene_id:146547|Hs108|chr16 ( 850) 553 122.3 1.4e-27
CCDS32436.1 PRSS36 gene_id:146547|Hs108|chr16 ( 855) 553 122.3 1.4e-27
CCDS30605.1 CELA2B gene_id:51032|Hs108|chr1 ( 269) 542 119.7 2.7e-27
CCDS13571.1 TMPRSS15 gene_id:5651|Hs108|chr21 (1019) 547 121.1 3.6e-27
>>CCDS10430.1 TPSG1 gene_id:25823|Hs108|chr16 (321 aa)
initn: 2278 init1: 2278 opt: 2278 Z-score: 2520.9 bits: 474.7 E(32554): 4.3e-134
Smith-Waterman score: 2278; 99.7% identity (99.7% similar) in 321 aa overlap (1-321:1-321)
10 20 30 40 50 60
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 HVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 EVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDACQDDSGGPLVCQVNGAWVQAGIV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
CCDS10 EVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDACQDDSGGPLVCQVNGAWVQAGTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 SWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSC
250 260 270 280 290 300
310 320
pF1KE6 VLLAKCLLHPSADGTPFPAPD
:::::::::::::::::::::
CCDS10 VLLAKCLLHPSADGTPFPAPD
310 320
>>CCDS10431.1 TPSAB1 gene_id:7177|Hs108|chr16 (275 aa)
initn: 725 init1: 311 opt: 817 Z-score: 907.3 bits: 175.9 E(32554): 3.2e-44
Smith-Waterman score: 817; 46.9% identity (72.2% similar) in 273 aa overlap (9-269:4-271)
10 20 30 40 50
pF1KE6 MALGACGLLLLLAVPGVSLRTLQ-PGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR
:::::.: .. :. :. :. .. .: ::::. :: . ::::.:::..
CCDS10 MLNLLLLALPVLASRAYAAPAPGQA-LQRVG--IVGGQEAPRSKWPWQVSLRVHG
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 ---VHVCGGSLLSPQWVLTAAHCFSGSLNS-SDYQVHLGELEITLSPHFSTVRQIILHSS
.: :::::. :::::::::: . .... . .:.: : .. . .. : .::.: .
CCDS10 PYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 -PSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLP
..: : .::::.:: ::..::.. : :: ::. : ::. ::::::: . . : ::
CCDS10 FYTAQIG--ADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLP
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 PPYSLREVKVSVVDTETCRRDY-----PGPGGSILQPDMLCARGPG-DACQDDSGGPLVC
::. :..::: ..... : : : :.. ::::: . :.:: ::::::::
CCDS10 PPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVC
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 QVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGF
.:::.:.:::.:::::::..:::::.:::: :..::....
CCDS10 KVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
240 250 260 270
290 300 310 320
pF1KE6 FLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
>>CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 (317 aa)
initn: 717 init1: 266 opt: 778 Z-score: 863.3 bits: 168.0 E(32554): 9.1e-42
Smith-Waterman score: 778; 42.6% identity (67.9% similar) in 277 aa overlap (3-267:15-287)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGV--SLRT-LQPGCGRPQVSDAGGRIVGGHAAP
::. ::::: .. . : . :.::.:: . :.:::. .
CCDS10 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLN---RVVGGEDST
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 AGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSD-YQVHLGELEITLSPHF
. ::: .:.. .: :.::::. .::.::::::. .::. ..: :: .. .:
CCDS10 DSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLG-NPGS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 ST----VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCW
. : . : : . :. .:::::.: . .: :.::.:::.:: . :. .::
CCDS10 RSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCW
120 130 140 150 160 170
170 180 190 200 210
pF1KE6 VTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDY-PGPGGSILQPDMLCA---RGPGD
..::: ..: ::: : .:...:: ..:.:.: . : : : . . ::::: .: :
CCDS10 ISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERD
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE6 ACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSE
:: ::::::.:::.:::. :::.::::::.. :::::: . :. .:...
CCDS10 ACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRG
240 250 260 270 280 290
280 290 300 310 320
pF1KE6 SGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
CCDS10 RAQGGGALRAPSQGSGAAARS
300 310
>>CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 (563 aa)
initn: 575 init1: 368 opt: 717 Z-score: 792.5 bits: 155.7 E(32554): 8e-38
Smith-Waterman score: 717; 42.4% identity (66.8% similar) in 262 aa overlap (18-274:306-563)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAG
: : .. :.. . :::::: : .
CCDS58 EVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDS
280 290 300 310 320 330
50 60 70 80 90 100
pF1KE6 AWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNS--SDYQVHLGELEITLSPHFS
::::.::.. .:.:::.:.. :::::::::: . .. ..:. : .. :. .
CCDS58 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA
340 350 360 370 380 390
110 120 130 140 150 160
pF1KE6 TVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWG
.. .::..:. . . ::::..:: :.:::..: :.::: .. : . ::.::.:
CCDS58 SIAEIIINSNYTDEEDDY-DIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFG
400 410 420 430 440 450
170 180 190 200 210 220
pF1KE6 YTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDS
::: . :. ::::.:...: . : :: : : : :.:: :: :.:: ::
CCDS58 KTRETDDKTSPF-LREVQVNLIDFKKCN-DYL-VYDSYLTPRMMCAGDLRGGRDSCQGDS
460 470 480 490 500 510
230 240 250 260 270 280
pF1KE6 GGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRL
::::::. :. : ::..::: :::. :.:::::.: . :: .. .:.:
CCDS58 GGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESSAG
520 530 540 550 560
290 300 310 320
pF1KE6 PLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
>>CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 (532 aa)
initn: 562 init1: 355 opt: 704 Z-score: 778.5 bits: 153.0 E(32554): 4.8e-37
Smith-Waterman score: 704; 43.1% identity (66.8% similar) in 253 aa overlap (18-265:271-519)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAG
: : .. :.. . :::::: : .
CCDS55 EVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDS
250 260 270 280 290 300
50 60 70 80 90 100
pF1KE6 AWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNS--SDYQVHLGELEITLSPHFS
::::.::.. .:.:::.:.. :::::::::: . .. ..:. : .. :. .
CCDS55 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA
310 320 330 340 350 360
110 120 130 140 150 160
pF1KE6 TVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWG
.. .::..:. . . ::::..:: :.:::..: :.::: .. : . ::.::.:
CCDS55 SIAEIIINSNYTDEEDDY-DIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFG
370 380 390 400 410
170 180 190 200 210 220
pF1KE6 YTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDS
::: . :. ::::.:...: . : :: : : : :.:: :: :.:: ::
CCDS55 KTRETDDKTSPF-LREVQVNLIDFKKCN-DYL-VYDSYLTPRMMCAGDLRGGRDSCQGDS
420 430 440 450 460 470
230 240 250 260 270 280
pF1KE6 GGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRL
::::::. :. : ::..::: :::. :.:::::.: . ::
CCDS55 GGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS
480 490 500 510 520 530
290 300 310 320
pF1KE6 PLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
>>CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 (567 aa)
initn: 562 init1: 355 opt: 704 Z-score: 778.1 bits: 153.0 E(32554): 5.1e-37
Smith-Waterman score: 704; 43.1% identity (66.8% similar) in 253 aa overlap (18-265:306-554)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAG
: : .. :.. . :::::: : .
CCDS41 EVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDS
280 290 300 310 320 330
50 60 70 80 90 100
pF1KE6 AWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNS--SDYQVHLGELEITLSPHFS
::::.::.. .:.:::.:.. :::::::::: . .. ..:. : .. :. .
CCDS41 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA
340 350 360 370 380 390
110 120 130 140 150 160
pF1KE6 TVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWG
.. .::..:. . . ::::..:: :.:::..: :.::: .. : . ::.::.:
CCDS41 SIAEIIINSNYTDEEDDY-DIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFG
400 410 420 430 440 450
170 180 190 200 210 220
pF1KE6 YTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDS
::: . :. ::::.:...: . : :: : : : :.:: :: :.:: ::
CCDS41 KTRETDDKTSPF-LREVQVNLIDFKKCN-DYL-VYDSYLTPRMMCAGDLRGGRDSCQGDS
460 470 480 490 500 510
230 240 250 260 270 280
pF1KE6 GGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRL
::::::. :. : ::..::: :::. :.:::::.: . ::
CCDS41 GGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS
520 530 540 550 560
290 300 310 320
pF1KE6 PLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
>>CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 (802 aa)
initn: 626 init1: 222 opt: 699 Z-score: 770.5 bits: 152.1 E(32554): 1.3e-36
Smith-Waterman score: 706; 40.1% identity (62.6% similar) in 289 aa overlap (6-270:522-802)
10 20 30
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGC-GRPQVSDA
:: . . .. .: : :::. :.
CCDS74 STCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDG
500 510 520 530 540 550
40 50 60 70 80
pF1KE6 G-------------GRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFS
. .::::: .. : :::::::..: :.:::.:.. .::.::::::.
CCDS74 SDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQ
560 570 580 590 600 610
90 100 110 120 130
pF1KE6 -GSLNSSD-YQVHLGEL-EITLSPHFST--VRQIILHSSPSGQPGTSG-DIALVELSVPV
:. :. . : ::.. . . : . : ...:: : . . :.::..:. ::
CCDS74 EDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH--PYHEEDSHDYDVALLQLDHPV
620 630 640 650 660
140 150 160 170 180 190
pF1KE6 TLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRD
. :. . ::::: : : ::..::.:::: ::: :. .:..: :... . : .
CCDS74 VRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPIS--NALQKVDVQLIPQDLCSEV
670 680 690 700 710 720
200 210 220 230 240 250
pF1KE6 YPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVCQ-VNGAWVQAGIVSWGEGCGRPNR
: . : :::: .: :::: ::::::::. ..: : ::.:::: ::::::
CCDS74 YRYQ----VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNY
730 740 750 760 770 780
260 270 280 290 300 310
pF1KE6 PGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPS
:::::. . ..::.. .:
CCDS74 FGVYTRITGVISWIQQVVT
790 800
>>CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 (811 aa)
initn: 626 init1: 222 opt: 699 Z-score: 770.5 bits: 152.1 E(32554): 1.4e-36
Smith-Waterman score: 706; 40.1% identity (62.6% similar) in 289 aa overlap (6-270:531-811)
10 20 30
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGC-GRPQVSDA
:: . . .. .: : :::. :.
CCDS13 STCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDG
510 520 530 540 550 560
40 50 60 70 80
pF1KE6 G-------------GRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFS
. .::::: .. : :::::::..: :.:::.:.. .::.::::::.
CCDS13 SDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQ
570 580 590 600 610 620
90 100 110 120 130
pF1KE6 -GSLNSSD-YQVHLGEL-EITLSPHFST--VRQIILHSSPSGQPGTSG-DIALVELSVPV
:. :. . : ::.. . . : . : ...:: : . . :.::..:. ::
CCDS13 EDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH--PYHEEDSHDYDVALLQLDHPV
630 640 650 660 670
140 150 160 170 180 190
pF1KE6 TLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRD
. :. . ::::: : : ::..::.:::: ::: :. .:..: :... . : .
CCDS13 VRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPIS--NALQKVDVQLIPQDLCSEV
680 690 700 710 720 730
200 210 220 230 240 250
pF1KE6 YPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVCQ-VNGAWVQAGIVSWGEGCGRPNR
: . : :::: .: :::: ::::::::. ..: : ::.:::: ::::::
CCDS13 YRYQ----VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNY
740 750 760 770 780 790
260 270 280 290 300 310
pF1KE6 PGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPS
:::::. . ..::.. .:
CCDS13 FGVYTRITGVISWIQQVVT
800 810
>>CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 (638 aa)
initn: 456 init1: 358 opt: 687 Z-score: 758.6 bits: 149.6 E(32554): 6.2e-36
Smith-Waterman score: 687; 41.3% identity (66.9% similar) in 269 aa overlap (16-274:369-630)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAP
: ::: . : . .. .. ::::: .
CCDS34 DCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSS
340 350 360 370 380 390
50 60 70 80 90
pF1KE6 AGAWPWQASLRLR---RVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGEL---EIT
: ::::.::... . :.:::::.. ::::::::::.: .. .... : : .::
CCDS34 WGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDIT
400 410 420 430 440 450
100 110 120 130 140 150
pF1KE6 LSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRC
. :: ...::.:.. . . :. ::::..:..:.. . :.::: .: :
CCDS34 KDTPFSQIKEIIIHQNYKVSEGNH-DIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNC
460 470 480 490 500 510
160 170 180 190 200 210
pF1KE6 WVTGWGYTRE-GEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPG
::::::...: :: :..:.. .: .: :.. : .: : :.:: .:
CCDS34 WVTGWGFSKEKGEI---QNILQKVNIPLVTNEECQKRYQD--YKITQ-RMVCAGYKEGGK
520 530 540 550 560 570
220 230 240 250 260 270
pF1KE6 DACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGS
:::. ::::::::. :: : .::.::::::.: ..:::::.: :..:: .. .: :
CCDS34 DACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDGK
580 590 600 610 620 630
280 290 300 310 320
pF1KE6 ESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
CCDS34 AQMQSPA
>>CCDS5279.1 PLG gene_id:5340|Hs108|chr6 (810 aa)
initn: 602 init1: 242 opt: 672 Z-score: 740.7 bits: 146.6 E(32554): 6.2e-35
Smith-Waterman score: 672; 43.0% identity (65.9% similar) in 249 aa overlap (26-265:567-803)
10 20 30 40 50
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQV--SDAGGRIVGGHAAPAGAWPWQA
::.::: . ::.::: .: .::::.
CCDS52 DVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQV
540 550 560 570 580 590
60 70 80 90 100 110
pF1KE6 SLRLRR-VHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLG-ELEITLSPHFSTVRQII
::: : .: :::.:.::.::::::::. : :.:.: :: . :..: :: . ..
CCDS52 SLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSR
600 610 620 630 640 650
120 130 140 150 160
pF1KE6 LHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTRE--
: : : ::::..:: :........:.::: . .:..:::: :.
CCDS52 LFLEP-----TRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTF
660 670 680 690 700 710
170 180 190 200 210 220
pF1KE6 GEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDSGGPL
: : :.:... :.....: : : .: . : ::: : :.:: ::::::
CCDS52 GAGL-----LKEAQLPVIENKVCNR-YEFLNGRV-QSTELCAGHLAGGTDSCQGDSGGPL
720 730 740 750 760
230 240 250 260 270 280
pF1KE6 VCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLA
:: . .. :..::: ::.:::.::::.:: .:.::
CCDS52 VCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
770 780 790 800 810
290 300 310 320
pF1KE6 GFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
321 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:24:59 2016 done: Tue Nov 8 12:24:59 2016
Total Scan time: 2.300 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]