Result of FASTA (omim) for
pFN21AE6351
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6351, 377 aa
1>>>pF1KE6351 377 - 377 aa - 377 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2652+/-0.000368; mu= 16.9335+/- 0.023
mean_var=63.7368+/-12.499, 0's: 0 Z-trim(113.0): 32 B-trim: 0 in 0/50
Lambda= 0.160649
statistics sampled from 22069 (22101) to 22069 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.259), width: 16
Scan time: 7.350
The best scores are: opt bits E(85289)
NP_110416 (OMIM: 607106) minor histocompatibility ( 377) 2453 577.3 2e-164
NP_848695 (OMIM: 607106) minor histocompatibility ( 394) 2285 538.3 1.1e-152
NP_848696 (OMIM: 607106) minor histocompatibility ( 426) 2285 538.4 1.2e-152
NP_848697 (OMIM: 607106) minor histocompatibility ( 143) 782 189.8 3.5e-48
XP_011526442 (OMIM: 608239) PREDICTED: signal pept ( 390) 208 56.9 9e-08
XP_016882508 (OMIM: 608239) PREDICTED: signal pept ( 444) 208 57.0 1e-07
XP_016882507 (OMIM: 608239) PREDICTED: signal pept ( 460) 208 57.0 1e-07
XP_016882506 (OMIM: 608239) PREDICTED: signal pept ( 461) 208 57.0 1e-07
XP_011526441 (OMIM: 608239) PREDICTED: signal pept ( 461) 208 57.0 1e-07
NP_694533 (OMIM: 608239) signal peptide peptidase- ( 592) 208 57.0 1.3e-07
NP_001070706 (OMIM: 608239) signal peptide peptida ( 511) 207 56.8 1.3e-07
XP_011526440 (OMIM: 608239) PREDICTED: signal pept ( 618) 208 57.1 1.3e-07
NP_787078 (OMIM: 608284) signal peptide peptidase- ( 684) 201 55.5 4.5e-07
NP_620584 (OMIM: 608240) signal peptide peptidase- ( 384) 180 50.5 8e-06
XP_011536227 (OMIM: 608240) PREDICTED: signal pept ( 384) 180 50.5 8e-06
XP_016878170 (OMIM: 608238) PREDICTED: signal pept ( 452) 152 44.0 0.00082
XP_016878169 (OMIM: 608238) PREDICTED: signal pept ( 470) 152 44.0 0.00085
NP_116191 (OMIM: 608238) signal peptide peptidase- ( 520) 152 44.0 0.00093
XP_005254779 (OMIM: 608238) PREDICTED: signal pept ( 538) 152 44.0 0.00096
>>NP_110416 (OMIM: 607106) minor histocompatibility anti (377 aa)
initn: 2453 init1: 2453 opt: 2453 Z-score: 3072.8 bits: 577.3 E(85289): 2e-164
Smith-Waterman score: 2453; 99.7% identity (99.7% similar) in 377 aa overlap (1-377:1-377)
10 20 30 40 50 60
pF1KE6 MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKFFEAPI
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_110 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESNPKDPAAVTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESNPKDPAAVTES
310 320 330 340 350 360
370
pF1KE6 KEGTEASASKGLEKKEK
:::::::::::::::::
NP_110 KEGTEASASKGLEKKEK
370
>>NP_848695 (OMIM: 607106) minor histocompatibility anti (394 aa)
initn: 2274 init1: 2274 opt: 2285 Z-score: 2862.0 bits: 538.3 E(85289): 1.1e-152
Smith-Waterman score: 2285; 93.1% identity (95.5% similar) in 379 aa overlap (1-375:1-379)
10 20 30 40 50 60
pF1KE6 MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKFFEAPI
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_848 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESN---PKDPAAV
::::::::::::::::::::::::::::::::::::::::::::::: : :. : .
NP_848 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT
310 320 330 340 350 360
360 370
pF1KE6 T-ESKEGTEASASKGLEKKEK
. :. :: . ....:
NP_848 HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAM
370 380 390
>>NP_848696 (OMIM: 607106) minor histocompatibility anti (426 aa)
initn: 2274 init1: 2274 opt: 2285 Z-score: 2861.5 bits: 538.4 E(85289): 1.2e-152
Smith-Waterman score: 2285; 93.1% identity (95.5% similar) in 379 aa overlap (1-375:1-379)
10 20 30 40 50 60
pF1KE6 MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKFFEAPI
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_848 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESN---PKDPAAV
::::::::::::::::::::::::::::::::::::::::::::::: : :. : .
NP_848 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT
310 320 330 340 350 360
360 370
pF1KE6 T-ESKEGTEASASKGLEKKEK
. :. :: . ....:
NP_848 HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAVTESKEGTEASASKG
370 380 390 400 410 420
>--
initn: 210 init1: 197 opt: 197 Z-score: 246.1 bits: 54.4 E(85289): 5.7e-07
Smith-Waterman score: 197; 100.0% identity (100.0% similar) in 32 aa overlap (346-377:395-426)
320 330 340 350 360 370
pF1KE6 QPALLYLVPACIGFPVLVALAKGEVTEMFSYEESNPKDPAAVTESKEGTEASASKGLEKK
::::::::::::::::::::::::::::::
NP_848 VSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAVTESKEGTEASASKGLEKK
370 380 390 400 410 420
pF1KE6 EK
::
NP_848 EK
>>NP_848697 (OMIM: 607106) minor histocompatibility anti (143 aa)
initn: 782 init1: 782 opt: 782 Z-score: 986.1 bits: 189.8 E(85289): 3.5e-48
Smith-Waterman score: 782; 100.0% identity (100.0% similar) in 121 aa overlap (1-121:1-121)
10 20 30 40 50 60
pF1KE6 MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
:
NP_848 IRSEGISLQHLKQLSREPVQGLG
130 140
>>XP_011526442 (OMIM: 608239) PREDICTED: signal peptide (390 aa)
initn: 276 init1: 106 opt: 208 Z-score: 260.5 bits: 56.9 E(85289): 9e-08
Smith-Waterman score: 300; 25.7% identity (55.0% similar) in 300 aa overlap (80-356:28-312)
50 60 70 80 90 100
pF1KE6 GALRSVRCARGKNASDMPETITSRDAARFPIIASCTLLGL-YLFFKIFSQEYINLLLSMY
.. :..: : : :. .. :..
XP_011 MKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDLLVYVVIGI-----
10 20 30 40 50
110 120 130 140 150 160
pF1KE6 FFVLGILALSHTISPFMNK--FFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCL
: . . .: ..: . . : .:: . : . . . . .. : :.
XP_011 FCLASATGLYSCLAPCVRRLPFGKCRIPNNS--LPYFHKRPQARMLLLA-------LFCV
60 70 80 90 100
170 180 190 200 210 220
pF1KE6 GLSSIVGVWYLLRK-HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF-
..: . ::. . :. .. .:.:: : .. ..: . .. .:: ::.::.:.::
XP_011 AVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFI
110 120 130 140 150 160
230 240 250 260
pF1KE6 -------GTNVMVTVAK-------FFEAPIKLVFPQ-DLLEKGLEANNFAMLGLGDVVIP
:...:: :: . :. : :. . .: :..::.::...:
XP_011 TPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVP
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE6 GIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGF
:...: ::::... ....:: . :: :: .:. . .....::::::::: .
XP_011 GLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVT
230 240 250 260 270 280
330 340 350 360 370
pF1KE6 PVLVALAKGEVTEMFS---YEESNPKDPAAVTESKEGTEASASKGLEKKEK
::: . :. ... . . : .: :
XP_011 SCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSP
290 300 310 320 330 340
>>XP_016882508 (OMIM: 608239) PREDICTED: signal peptide (444 aa)
initn: 276 init1: 106 opt: 208 Z-score: 259.7 bits: 57.0 E(85289): 1e-07
Smith-Waterman score: 305; 24.3% identity (55.4% similar) in 350 aa overlap (39-356:31-366)
10 20 30 40 50 60
pF1KE6 HNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGAL----RSVRCARGKNAS
...::. . .:. :.:. .. .
XP_016 MLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKKYMKHKRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT----
: :: .. . :.. .:... . . .. . .::. . :.::. :. .
XP_016 DGPEKQEDEAVDVTPVM-TCVFVVMCCSMLVLLYYFYDLLV---YVVIGIFCLASATGLY
70 80 90 100 110
130 140 150 160 170
pF1KE6 --ISPFMNK--FFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWY
..: . . : .:: .: . . . . .. : :...: . ::.
XP_016 SCLAPCVRRLPFGKCRIPNN--SLPYFHKRPQARMLLLA-------LFCVAVSVVWGVFR
120 130 140 150 160
180 190 200 210 220
pF1KE6 LLRK-HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GTN
. :. .. .:.:: : .. ..: . .. .:: ::.::.:.:: :..
XP_016 NEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGSS
170 180 190 200 210 220
230 240 250 260 270
pF1KE6 VMVTVAK-------FFEAPIKLVFPQ-DLLEKGLEANNFAMLGLGDVVIPGIFIALLLRF
.:: :: . :. : :. . .: :..::.::...::...: ::
XP_016 IMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRF
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE6 DISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGE
::... ....:: . :: :: .:. . .....::::::::: . ::: . :
XP_016 DIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRE
290 300 310 320 330 340
340 350 360 370
pF1KE6 VTEMFS---YEESNPKDPAAVTESKEGTEASASKGLEKKEK
. ... . . : .: :
XP_016 LGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSR
350 360 370 380 390 400
>>XP_016882507 (OMIM: 608239) PREDICTED: signal peptide (460 aa)
initn: 276 init1: 106 opt: 208 Z-score: 259.4 bits: 57.0 E(85289): 1e-07
Smith-Waterman score: 305; 24.3% identity (55.4% similar) in 350 aa overlap (39-356:47-382)
10 20 30 40 50 60
pF1KE6 HNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGAL----RSVRCARGKNAS
...::. . .:. :.:. .. .
XP_016 WTSSRQRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKKYMKHKRD
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE6 DMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT----
: :: .. . :.. .:... . . .. . .::. . :.::. :. .
XP_016 DGPEKQEDEAVDVTPVM-TCVFVVMCCSMLVLLYYFYDLLV---YVVIGIFCLASATGLY
80 90 100 110 120 130
130 140 150 160 170
pF1KE6 --ISPFMNK--FFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWY
..: . . : .:: .: . . . . .. : :...: . ::.
XP_016 SCLAPCVRRLPFGKCRIPNN--SLPYFHKRPQARMLLLA-------LFCVAVSVVWGVFR
140 150 160 170 180
180 190 200 210 220
pF1KE6 LLRK-HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GTN
. :. .. .:.:: : .. ..: . .. .:: ::.::.:.:: :..
XP_016 NEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGSS
190 200 210 220 230 240
230 240 250 260 270
pF1KE6 VMVTVAK-------FFEAPIKLVFPQ-DLLEKGLEANNFAMLGLGDVVIPGIFIALLLRF
.:: :: . :. : :. . .: :..::.::...::...: ::
XP_016 IMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRF
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 DISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGE
::... ....:: . :: :: .:. . .....::::::::: . ::: . :
XP_016 DIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRE
310 320 330 340 350 360
340 350 360 370
pF1KE6 VTEMFS---YEESNPKDPAAVTESKEGTEASASKGLEKKEK
. ... . . : .: :
XP_016 LGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSR
370 380 390 400 410 420
>>XP_016882506 (OMIM: 608239) PREDICTED: signal peptide (461 aa)
initn: 276 init1: 106 opt: 208 Z-score: 259.4 bits: 57.0 E(85289): 1e-07
Smith-Waterman score: 301; 24.5% identity (55.3% similar) in 351 aa overlap (39-356:47-383)
10 20 30 40 50 60
pF1KE6 HNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGAL----RSVRCARGKNA-
...::. . .:. :.:. :.
XP_016 WTSSRQRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKR
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE6 SDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT---
.: :: .. . :.. .:... . . .. . .::. . :.::. :. .
XP_016 DDGPEKQEDEAVDVTPVM-TCVFVVMCCSMLVLLYYFYDLLV---YVVIGIFCLASATGL
80 90 100 110 120 130
130 140 150 160 170
pF1KE6 ---ISPFMNK--FFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVW
..: . . : .:: .: . . . . .. : :...: . ::.
XP_016 YSCLAPCVRRLPFGKCRIPNN--SLPYFHKRPQARMLLLA-------LFCVAVSVVWGVF
140 150 160 170 180
180 190 200 210 220
pF1KE6 YLLRK-HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GT
. :. .. .:.:: : .. ..: . .. .:: ::.::.:.:: :.
XP_016 RNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGS
190 200 210 220 230 240
230 240 250 260 270
pF1KE6 NVMVTVAK-------FFEAPIKLVFPQ-DLLEKGLEANNFAMLGLGDVVIPGIFIALLLR
..:: :: . :. : :. . .: :..::.::...::...: :
XP_016 SIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 FDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKG
:::... ....:: . :: :: .:. . .....::::::::: . ::: .
XP_016 FDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRR
310 320 330 340 350 360
340 350 360 370
pF1KE6 EVTEMFS---YEESNPKDPAAVTESKEGTEASASKGLEKKEK
:. ... . . : .: :
XP_016 ELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKS
370 380 390 400 410 420
>>XP_011526441 (OMIM: 608239) PREDICTED: signal peptide (461 aa)
initn: 276 init1: 106 opt: 208 Z-score: 259.4 bits: 57.0 E(85289): 1e-07
Smith-Waterman score: 301; 24.5% identity (55.3% similar) in 351 aa overlap (39-356:47-383)
10 20 30 40 50 60
pF1KE6 HNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGAL----RSVRCARGKNA-
...::. . .:. :.:. :.
XP_011 WTSSRQRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKR
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE6 SDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT---
.: :: .. . :.. .:... . . .. . .::. . :.::. :. .
XP_011 DDGPEKQEDEAVDVTPVM-TCVFVVMCCSMLVLLYYFYDLLV---YVVIGIFCLASATGL
80 90 100 110 120 130
130 140 150 160 170
pF1KE6 ---ISPFMNK--FFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVW
..: . . : .:: .: . . . . .. : :...: . ::.
XP_011 YSCLAPCVRRLPFGKCRIPNN--SLPYFHKRPQARMLLLA-------LFCVAVSVVWGVF
140 150 160 170 180
180 190 200 210 220
pF1KE6 YLLRK-HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GT
. :. .. .:.:: : .. ..: . .. .:: ::.::.:.:: :.
XP_011 RNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGS
190 200 210 220 230 240
230 240 250 260 270
pF1KE6 NVMVTVAK-------FFEAPIKLVFPQ-DLLEKGLEANNFAMLGLGDVVIPGIFIALLLR
..:: :: . :. : :. . .: :..::.::...::...: :
XP_011 SIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 FDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKG
:::... ....:: . :: :: .:. . .....::::::::: . ::: .
XP_011 FDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRR
310 320 330 340 350 360
340 350 360 370
pF1KE6 EVTEMFS---YEESNPKDPAAVTESKEGTEASASKGLEKKEK
:. ... . . : .: :
XP_011 ELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKS
370 380 390 400 410 420
>>NP_694533 (OMIM: 608239) signal peptide peptidase-like (592 aa)
initn: 276 init1: 106 opt: 208 Z-score: 257.8 bits: 57.0 E(85289): 1.3e-07
Smith-Waterman score: 301; 24.5% identity (55.3% similar) in 351 aa overlap (39-356:178-514)
10 20 30 40 50 60
pF1KE6 HNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGAL----RSVRCARGKNA-
...::. . .:. :.:. :.
NP_694 MLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKR
150 160 170 180 190 200
70 80 90 100 110 120
pF1KE6 SDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT---
.: :: .. . :.. .:... . . .. . .::. . :.::. :. .
NP_694 DDGPEKQEDEAVDVTPVM-TCVFVVMCCSMLVLLYYFYDLLV---YVVIGIFCLASATGL
210 220 230 240 250 260
130 140 150 160 170
pF1KE6 ---ISPFMNK--FFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVW
..: . . : .:: .: . . . . .. : :...: . ::.
NP_694 YSCLAPCVRRLPFGKCRIPNN--SLPYFHKRPQARMLLLA-------LFCVAVSVVWGVF
270 280 290 300 310
180 190 200 210 220
pF1KE6 YLLRK-HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GT
. :. .. .:.:: : .. ..: . .. .:: ::.::.:.:: :.
NP_694 RNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGS
320 330 340 350 360 370
230 240 250 260 270
pF1KE6 NVMVTVAK-------FFEAPIKLVFPQ-DLLEKGLEANNFAMLGLGDVVIPGIFIALLLR
..:: :: . :. : :. . .: :..::.::...::...: :
NP_694 SIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHR
380 390 400 410 420 430
280 290 300 310 320 330
pF1KE6 FDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKG
:::... ....:: . :: :: .:. . .....::::::::: . ::: .
NP_694 FDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRR
440 450 460 470 480 490
340 350 360 370
pF1KE6 EVTEMFS---YEESNPKDPAAVTESKEGTEASASKGLEKKEK
:. ... . . : .: :
NP_694 ELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKS
500 510 520 530 540 550
377 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:22:44 2016 done: Tue Nov 8 12:22:45 2016
Total Scan time: 7.350 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]