Result of FASTA (omim) for
pFN21AE6348
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6348, 331 aa
1>>>pF1KE6348 331 - 331 aa - 331 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8552+/-0.000355; mu= 18.2557+/- 0.022
mean_var=58.7744+/-11.946, 0's: 0 Z-trim(112.6): 53 B-trim: 0 in 0/53
Lambda= 0.167294
statistics sampled from 21487 (21540) to 21487 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.253), width: 16
Scan time: 5.160
The best scores are: opt bits E(85289)
NP_036199 (OMIM: 608477) aflatoxin B1 aldehyde red ( 331) 2247 550.7 1.6e-156
NP_003680 (OMIM: 603418) aflatoxin B1 aldehyde red ( 359) 1999 490.8 1.8e-138
XP_011539348 (OMIM: 608477) PREDICTED: aflatoxin B ( 375) 1890 464.5 1.5e-130
XP_016856203 (OMIM: 608477) PREDICTED: aflatoxin B ( 304) 1428 353.0 4.7e-97
NP_001307908 (OMIM: 603418) aflatoxin B1 aldehyde ( 324) 1077 268.3 1.6e-71
NP_742128 (OMIM: 601142) voltage-gated potassium c ( 353) 267 72.8 1.2e-12
XP_005263571 (OMIM: 601142) PREDICTED: voltage-gat ( 353) 267 72.8 1.2e-12
NP_001186789 (OMIM: 601142) voltage-gated potassiu ( 367) 267 72.8 1.2e-12
NP_003627 (OMIM: 601142) voltage-gated potassium c ( 367) 267 72.8 1.2e-12
NP_001186790 (OMIM: 601142) voltage-gated potassiu ( 367) 267 72.8 1.2e-12
XP_016858109 (OMIM: 601142) PREDICTED: voltage-gat ( 400) 267 72.8 1.3e-12
XP_016858107 (OMIM: 601142) PREDICTED: voltage-gat ( 420) 267 72.9 1.4e-12
XP_016858108 (OMIM: 601142) PREDICTED: voltage-gat ( 420) 267 72.9 1.4e-12
NP_001186792 (OMIM: 601142) voltage-gated potassiu ( 300) 263 71.8 2.1e-12
XP_011540623 (OMIM: 601142) PREDICTED: voltage-gat ( 395) 264 72.1 2.2e-12
XP_011540624 (OMIM: 601142) PREDICTED: voltage-gat ( 395) 264 72.1 2.2e-12
XP_011511417 (OMIM: 601141) PREDICTED: voltage-gat ( 337) 261 71.4 3.2e-12
XP_016862660 (OMIM: 601141) PREDICTED: voltage-gat ( 337) 261 71.4 3.2e-12
XP_016862661 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 260 71.1 3.3e-12
XP_016862662 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 260 71.1 3.3e-12
XP_011511419 (OMIM: 601141) PREDICTED: voltage-gat ( 295) 260 71.1 3.3e-12
NP_751891 (OMIM: 601141) voltage-gated potassium c ( 401) 261 71.4 3.6e-12
NP_003462 (OMIM: 601141) voltage-gated potassium c ( 408) 261 71.4 3.7e-12
XP_011511418 (OMIM: 601141) PREDICTED: voltage-gat ( 334) 260 71.1 3.7e-12
NP_751892 (OMIM: 601141) voltage-gated potassium c ( 419) 261 71.4 3.8e-12
XP_016880793 (OMIM: 604111) PREDICTED: voltage-gat ( 384) 228 63.4 8.8e-10
NP_004723 (OMIM: 604111) voltage-gated potassium c ( 404) 228 63.4 9.1e-10
XP_011522370 (OMIM: 604111) PREDICTED: voltage-gat ( 411) 228 63.4 9.3e-10
NP_001345 (OMIM: 600450,614279) aldo-keto reductas ( 323) 176 50.8 4.6e-06
NP_995317 (OMIM: 600450,614279) aldo-keto reductas ( 323) 176 50.8 4.6e-06
NP_001344 (OMIM: 600449) aldo-keto reductase famil ( 323) 176 50.8 4.6e-06
NP_001809 (OMIM: 600451,614279) aldo-keto reductas ( 323) 171 49.6 1.1e-05
NP_001240837 (OMIM: 603966) aldo-keto reductase fa ( 323) 155 45.8 0.00015
NP_003730 (OMIM: 603966) aldo-keto reductase famil ( 323) 155 45.8 0.00015
NP_001307956 (OMIM: 600450,614279) aldo-keto reduc ( 297) 147 43.8 0.00055
XP_016871280 (OMIM: 600449) PREDICTED: aldo-keto r ( 297) 147 43.8 0.00055
NP_001128713 (OMIM: 600450,614279) aldo-keto reduc ( 139) 141 42.2 0.0008
XP_016862663 (OMIM: 601141) PREDICTED: voltage-gat ( 233) 139 41.8 0.0017
NP_001240838 (OMIM: 603966) aldo-keto reductase fa ( 138) 128 39.0 0.007
>>NP_036199 (OMIM: 608477) aflatoxin B1 aldehyde reducta (331 aa)
initn: 2247 init1: 2247 opt: 2247 Z-score: 2931.1 bits: 550.7 E(85289): 1.6e-156
Smith-Waterman score: 2247; 99.4% identity (100.0% similar) in 331 aa overlap (1-331:1-331)
10 20 30 40 50 60
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEH
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_036 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA
250 260 270 280 290 300
310 320 330
pF1KE6 AAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
::::::::::::::::::::::.::::::::
NP_036 AAEEGPLEPAVVDAFNQAWHLVTHECPNYFR
310 320 330
>>NP_003680 (OMIM: 603418) aflatoxin B1 aldehyde reducta (359 aa)
initn: 1994 init1: 1994 opt: 1999 Z-score: 2607.1 bits: 490.8 E(85289): 1.8e-138
Smith-Waterman score: 1999; 87.2% identity (95.2% similar) in 335 aa overlap (2-331:25-359)
10 20 30
pF1KE6 MSRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVT
.: :. .:: :.:::.::::::::::.:::..
NP_003 MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 RAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLR
::::::::::.::::.::.:::::::::::: :::.:::::: ::: : :.::::::.:
NP_003 RAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 FQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAE
::::::::::::.::::::: :::.:::::::.::..::::::::::::::::.:::::
NP_003 SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 ICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYE
:::::::::::::::::::::: :::::::::::::::::::::.:::::::::::::::
NP_003 ICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 DKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMY
::::::::::::::.::: ::::.:::::::.::::::::::::::::::.:::.:::::
NP_003 DKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 HHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
:::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_003 HHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR
310 320 330 340 350
>>XP_011539348 (OMIM: 608477) PREDICTED: aflatoxin B1 al (375 aa)
initn: 1890 init1: 1890 opt: 1890 Z-score: 2464.7 bits: 464.5 E(85289): 1.5e-130
Smith-Waterman score: 1890; 99.6% identity (100.0% similar) in 278 aa overlap (1-278:1-278)
10 20 30 40 50 60
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEH
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_011 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA
::::::::::::::::::::::::::::::::::::::
XP_011 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQVQNSMPTVLFFQDFNHVTPRGR
250 260 270 280 290 300
310 320 330
pF1KE6 AAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
XP_011 CFEPLVSLILQDHTAGRQDSPYLGPPHPLSSLLEETETWDSSGAGEAEGWGTTGQGGVPD
310 320 330 340 350 360
>>XP_016856203 (OMIM: 608477) PREDICTED: aflatoxin B1 al (304 aa)
initn: 1428 init1: 1428 opt: 1428 Z-score: 1863.4 bits: 353.0 E(85289): 4.7e-97
Smith-Waterman score: 1428; 99.0% identity (100.0% similar) in 207 aa overlap (72-278:1-207)
50 60 70 80 90 100
pF1KE6 EIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKR
.:::::::::::::::::::::::::::::
XP_016 MKIDTKAIPLFGNSLKPDSLRFQLETSLKR
10 20 30
110 120 130 140 150 160
pF1KE6 LQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 WILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVG
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_016 WILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 RFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQVQN
160 170 180 190 200 210
290 300 310 320 330
pF1KE6 GDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
XP_016 SMPTVLFFQDFNHVTPRGRCFEPLVSLILQDHTAGRQDSPYLGPPHPLSSLLEETETWDS
220 230 240 250 260 270
>>NP_001307908 (OMIM: 603418) aflatoxin B1 aldehyde redu (324 aa)
initn: 1077 init1: 1077 opt: 1077 Z-score: 1405.1 bits: 268.3 E(85289): 1.6e-71
Smith-Waterman score: 1678; 77.0% identity (84.8% similar) in 335 aa overlap (2-331:25-324)
10 20 30
pF1KE6 MSRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVT
.: :. .:: :.:::.::::::::::.:::..
NP_001 MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 RAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLR
::::::::::.::::.::.:::::::::::: :::.:::::: ::: : :.::::::.:
NP_001 RAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 FQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAE
::::::::::::.::::::: :::.:::::::.::..:::::
NP_001 SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEG-----------------
130 140 150 160
160 170 180 190 200 210
pF1KE6 ICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYE
:::: :::::::::::::::::::::.:::::::::::::::
NP_001 ------------------MYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYE
170 180 190 200
220 230 240 250 260 270
pF1KE6 DKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMY
::::::::::::::.::: ::::.:::::::.::::::::::::::::::.:::.:::::
NP_001 DKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMY
210 220 230 240 250 260
280 290 300 310 320 330
pF1KE6 HHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
:::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 HHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR
270 280 290 300 310 320
>>NP_742128 (OMIM: 601142) voltage-gated potassium chann (353 aa)
initn: 222 init1: 109 opt: 267 Z-score: 348.0 bits: 72.8 E(85289): 1.2e-12
Smith-Waterman score: 291; 28.8% identity (57.2% similar) in 299 aa overlap (20-306:48-327)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. . : . .::: ::
NP_742 TGSPGMIYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY-DNGINLFDTAEVY
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:..::.. . : . : :: : :.. .: . :..::.:::
NP_742 AAGKAEVVLGNIIKKKGWRRSSLVITTK-IFWGGKAETERGLSRKHIIEGLKASLERLQL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:::.:: .. ..: . : : ... :. : .. .. .
NP_742 EYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTP
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
: :. :. . :. ::..: : : : .:. ....::: :...::: .: : .:
NP_742 PICEQAEYHMFQREKVEVQL-PELFHKIGVGAMTWSPLACGIVSGKYD----SGIPPYSR
200 210 220 230 240 250
230 240 250 260 270
pF1KE6 --FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAA---YGASAPSMTSATLRWMYHHSQL
. : : ... .:. . : . : ::: : . :... : : ..
NP_742 ASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAIA---WCLRN---
260 270 280 290 300
280 290 300 310 320 330
pF1KE6 QGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
.:. ..:.:: :. .:: .:..: . :
NP_742 EGV--SSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
310 320 330 340 350
>>XP_005263571 (OMIM: 601142) PREDICTED: voltage-gated p (353 aa)
initn: 222 init1: 109 opt: 267 Z-score: 348.0 bits: 72.8 E(85289): 1.2e-12
Smith-Waterman score: 291; 28.8% identity (57.2% similar) in 299 aa overlap (20-306:48-327)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. . : . .::: ::
XP_005 TGSPGMIYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY-DNGINLFDTAEVY
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:..::.. . : . : :: : :.. .: . :..::.:::
XP_005 AAGKAEVVLGNIIKKKGWRRSSLVITTK-IFWGGKAETERGLSRKHIIEGLKASLERLQL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:::.:: .. ..: . : : ... :. : .. .. .
XP_005 EYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTP
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
: :. :. . :. ::..: : : : .:. ....::: :...::: .: : .:
XP_005 PICEQAEYHMFQREKVEVQL-PELFHKIGVGAMTWSPLACGIVSGKYD----SGIPPYSR
200 210 220 230 240 250
230 240 250 260 270
pF1KE6 --FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAA---YGASAPSMTSATLRWMYHHSQL
. : : ... .:. . : . : ::: : . :... : : ..
XP_005 ASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAIA---WCLRN---
260 270 280 290 300
280 290 300 310 320 330
pF1KE6 QGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
.:. ..:.:: :. .:: .:..: . :
XP_005 EGV--SSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
310 320 330 340 350
>>NP_001186789 (OMIM: 601142) voltage-gated potassium ch (367 aa)
initn: 222 init1: 109 opt: 267 Z-score: 347.8 bits: 72.8 E(85289): 1.2e-12
Smith-Waterman score: 291; 28.8% identity (57.2% similar) in 299 aa overlap (20-306:62-341)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. . : . .::: ::
NP_001 PKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY-DNGINLFDTAEVY
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:..::.. . : . : :: : :.. .: . :..::.:::
NP_001 AAGKAEVVLGNIIKKKGWRRSSLVITTK-IFWGGKAETERGLSRKHIIEGLKASLERLQL
100 110 120 130 140
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:::.:: .. ..: . : : ... :. : .. .. .
NP_001 EYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTP
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
: :. :. . :. ::..: : : : .:. ....::: :...::: .: : .:
NP_001 PICEQAEYHMFQREKVEVQL-PELFHKIGVGAMTWSPLACGIVSGKYD----SGIPPYSR
210 220 230 240 250 260
230 240 250 260 270
pF1KE6 --FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAA---YGASAPSMTSATLRWMYHHSQL
. : : ... .:. . : . : ::: : . :... : : ..
NP_001 ASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAIA---WCLRN---
270 280 290 300 310
280 290 300 310 320 330
pF1KE6 QGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
.:. ..:.:: :. .:: .:..: . :
NP_001 EGV--SSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
320 330 340 350 360
>>NP_003627 (OMIM: 601142) voltage-gated potassium chann (367 aa)
initn: 222 init1: 109 opt: 267 Z-score: 347.8 bits: 72.8 E(85289): 1.2e-12
Smith-Waterman score: 291; 28.8% identity (57.2% similar) in 299 aa overlap (20-306:62-341)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. . : . .::: ::
NP_003 PKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY-DNGINLFDTAEVY
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:..::.. . : . : :: : :.. .: . :..::.:::
NP_003 AAGKAEVVLGNIIKKKGWRRSSLVITTK-IFWGGKAETERGLSRKHIIEGLKASLERLQL
100 110 120 130 140
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:::.:: .. ..: . : : ... :. : .. .. .
NP_003 EYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTP
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
: :. :. . :. ::..: : : : .:. ....::: :...::: .: : .:
NP_003 PICEQAEYHMFQREKVEVQL-PELFHKIGVGAMTWSPLACGIVSGKYD----SGIPPYSR
210 220 230 240 250 260
230 240 250 260 270
pF1KE6 --FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAA---YGASAPSMTSATLRWMYHHSQL
. : : ... .:. . : . : ::: : . :... : : ..
NP_003 ASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAIA---WCLRN---
270 280 290 300 310
280 290 300 310 320 330
pF1KE6 QGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
.:. ..:.:: :. .:: .:..: . :
NP_003 EGV--SSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
320 330 340 350 360
>>NP_001186790 (OMIM: 601142) voltage-gated potassium ch (367 aa)
initn: 222 init1: 109 opt: 267 Z-score: 347.8 bits: 72.8 E(85289): 1.2e-12
Smith-Waterman score: 291; 28.8% identity (57.2% similar) in 299 aa overlap (20-306:62-341)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. . : . .::: ::
NP_001 PKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY-DNGINLFDTAEVY
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:..::.. . : . : :: : :.. .: . :..::.:::
NP_001 AAGKAEVVLGNIIKKKGWRRSSLVITTK-IFWGGKAETERGLSRKHIIEGLKASLERLQL
100 110 120 130 140
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:::.:: .. ..: . : : ... :. : .. .. .
NP_001 EYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTP
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
: :. :. . :. ::..: : : : .:. ....::: :...::: .: : .:
NP_001 PICEQAEYHMFQREKVEVQL-PELFHKIGVGAMTWSPLACGIVSGKYD----SGIPPYSR
210 220 230 240 250 260
230 240 250 260 270
pF1KE6 --FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAA---YGASAPSMTSATLRWMYHHSQL
. : : ... .:. . : . : ::: : . :... : : ..
NP_001 ASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAIA---WCLRN---
270 280 290 300 310
280 290 300 310 320 330
pF1KE6 QGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
.:. ..:.:: :. .:: .:..: . :
NP_001 EGV--SSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
320 330 340 350 360
331 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:20:57 2016 done: Tue Nov 8 12:20:58 2016
Total Scan time: 5.160 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]