Result of FASTA (ccds) for
pFN21AE6347
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6347, 327 aa
1>>>pF1KE6347 327 - 327 aa - 327 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0851+/-0.000758; mu= 16.6238+/- 0.046
mean_var=60.9907+/-12.034, 0's: 0 Z-trim(108.0): 49 B-trim: 119 in 1/49
Lambda= 0.164226
statistics sampled from 9866 (9915) to 9866 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.305), width: 16
Scan time: 2.250
The best scores are: opt bits E(32554)
CCDS43595.1 FKBP6 gene_id:8468|Hs108|chr7 ( 327) 2200 529.6 1.3e-150
CCDS47604.1 FKBP6 gene_id:8468|Hs108|chr7 ( 322) 2078 500.7 6.6e-142
CCDS64670.1 FKBP6 gene_id:8468|Hs108|chr7 ( 297) 1616 391.2 5.5e-109
CCDS54996.1 FKBP5 gene_id:2289|Hs108|chr6 ( 268) 280 74.6 9.7e-14
CCDS4808.1 FKBP5 gene_id:2289|Hs108|chr6 ( 457) 280 74.8 1.5e-13
CCDS8512.1 FKBP4 gene_id:2288|Hs108|chr12 ( 459) 262 70.5 2.9e-12
>>CCDS43595.1 FKBP6 gene_id:8468|Hs108|chr7 (327 aa)
initn: 2200 init1: 2200 opt: 2200 Z-score: 2817.3 bits: 529.6 E(32554): 1.3e-150
Smith-Waterman score: 2200; 100.0% identity (100.0% similar) in 327 aa overlap (1-327:1-327)
10 20 30 40 50 60
pF1KE6 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 YSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLNLSFTYLKLDRPTIALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLNLSFTYLKLDRPTIALC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 YGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCY
250 260 270 280 290 300
310 320
pF1KE6 RDYVDKEKEMWHRMFAPCGDGSTAGES
:::::::::::::::::::::::::::
CCDS43 RDYVDKEKEMWHRMFAPCGDGSTAGES
310 320
>>CCDS47604.1 FKBP6 gene_id:8468|Hs108|chr7 (322 aa)
initn: 2078 init1: 2078 opt: 2078 Z-score: 2661.2 bits: 500.7 E(32554): 6.6e-142
Smith-Waterman score: 2078; 99.4% identity (99.7% similar) in 311 aa overlap (17-327:12-322)
10 20 30 40 50 60
pF1KE6 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVK
: .:::::::::::::::::::::::::::::::::::::::::
CCDS47 MSASSWPQNGMPPSSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVK
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 YSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 LGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 LFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLNLSFTYLKLDRPTIALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLNLSFTYLKLDRPTIALC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 YGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 YGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCY
240 250 260 270 280 290
310 320
pF1KE6 RDYVDKEKEMWHRMFAPCGDGSTAGES
:::::::::::::::::::::::::::
CCDS47 RDYVDKEKEMWHRMFAPCGDGSTAGES
300 310 320
>>CCDS64670.1 FKBP6 gene_id:8468|Hs108|chr7 (297 aa)
initn: 1977 init1: 1616 opt: 1616 Z-score: 2070.1 bits: 391.2 E(32554): 5.5e-109
Smith-Waterman score: 1921; 90.8% identity (90.8% similar) in 327 aa overlap (1-327:1-297)
10 20 30 40 50 60
pF1KE6 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVL--
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGT
::::::::::::::::::::::::::::::::
CCDS64 ----------------------------DITLWGMELGLLSMRRGELARFLFKPNYAYGT
60 70 80 90
130 140 150 160 170 180
pF1KE6 LGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNY
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 LFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLNLSFTYLKLDRPTIALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLNLSFTYLKLDRPTIALC
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE6 YGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 YGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCY
220 230 240 250 260 270
310 320
pF1KE6 RDYVDKEKEMWHRMFAPCGDGSTAGES
:::::::::::::::::::::::::::
CCDS64 RDYVDKEKEMWHRMFAPCGDGSTAGES
280 290
>>CCDS54996.1 FKBP5 gene_id:2289|Hs108|chr6 (268 aa)
initn: 248 init1: 248 opt: 280 Z-score: 360.1 bits: 74.6 E(32554): 9.7e-14
Smith-Waterman score: 280; 37.9% identity (69.3% similar) in 140 aa overlap (7-142:4-137)
10 20 30 40 50
pF1KE6 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISG--DRGVLKDVIREGAGDLVAP--DAS
..:. .....: .. :. ::.. :::::: : : : :. . : .
CCDS54 MTTDEGAKNNEESPTATVAEQGE----DITSKKDRGVLKIVKRVGNGEET-PMIGDK
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNY
: :.:.: : . . :::.. :. : ...::. .. . ..:. .:..::. ..: ::.:
CCDS54 VYVHYKGKLSN-GKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 AYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATERE
:::. : : :: :.:..::::::::
CCDS54 AYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIH
120 130 140 150 160 170
>>CCDS4808.1 FKBP5 gene_id:2289|Hs108|chr6 (457 aa)
initn: 382 init1: 248 opt: 280 Z-score: 356.6 bits: 74.8 E(32554): 1.5e-13
Smith-Waterman score: 282; 25.3% identity (57.3% similar) in 288 aa overlap (31-315:141-413)
10 20 30 40 50 60
pF1KE6 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVK
:. : :... . :.: : :. .. :.
CCDS48 YAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEG-YSNPNEGATVE
120 130 140 150 160
70 80 90 100 110
pF1KE6 YSGYLEHMDRPFDSNYFRKTPRLMKLGEDITL-WGMELGLLSMRRGELARFLFKPNYAYG
. : :: : . . ::: . :.. .: .:.: : . . : :..:
CCDS48 IHLEGRCGGRMFDC---RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFG
170 180 190 200 210 220
120 130 140 150 160 170
pF1KE6 TLGCPPL-IPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFG
: : . : ::. ...:. : .: : : :.. . :.. :: .: :
CCDS48 EAGKPKFGIEPNAELIYEVTLKSFEKAKE-------SWEMDTKEKLEQ----AAIVKEKG
230 240 250 260 270
180 190 200 210 220 230
pF1KE6 NYLFRQNRFYDAKVRYKRALLLLRRRSAPPE-EQHLVEAAKLPVLLNLSFTYLKLDRPTI
. :. .....: ..: . . :. . . : :.. :. : ..:::.. :::: . :
CCDS48 TVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTK
280 290 300 310 320 330
240 250 260 270 280 290
pF1KE6 ALCYGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLA
:. ..:: .:. : :.:.: :.: ::..:...:. . .. . .: :. ...
CCDS48 AVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQ
340 350 360 370 380 390
300 310 320
pF1KE6 SCYRDYVDKEKEMWHRMFAPCGDGSTAGES
. ... ....... ::
CCDS48 KKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEG
400 410 420 430 440 450
>--
initn: 382 init1: 248 opt: 280 Z-score: 356.6 bits: 74.8 E(32554): 1.5e-13
Smith-Waterman score: 280; 37.9% identity (69.3% similar) in 140 aa overlap (7-142:4-137)
10 20 30 40 50
pF1KE6 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISG--DRGVLKDVIREGAGDLVAP--DAS
..:. .....: .. :. ::.. :::::: : : : :. . : .
CCDS48 MTTDEGAKNNEESPTATVAEQGE----DITSKKDRGVLKIVKRVGNGEET-PMIGDK
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNY
: :.:.: : . . :::.. :. : ...::. .. . ..:. .:..::. ..: ::.:
CCDS48 VYVHYKGKLSN-GKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 AYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATERE
:::. : : :: :.:..::::::::
CCDS48 AYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIH
120 130 140 150 160 170
>>CCDS8512.1 FKBP4 gene_id:2288|Hs108|chr12 (459 aa)
initn: 361 init1: 220 opt: 262 Z-score: 333.6 bits: 70.5 E(32554): 2.9e-12
Smith-Waterman score: 332; 26.9% identity (61.2% similar) in 286 aa overlap (35-315:147-415)
10 20 30 40 50 60
pF1KE6 ALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVKYS--
: :... . .: : . :. ...:. .
CCDS85 GSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEG-YAKPNEGAIVEVALE
120 130 140 150 160 170
70 80 90 100 110 120
pF1KE6 GYLEHMDRPFDSNYFRKTPRLMKLGEDITL-WGMELGLLSMRRGELARFLFKPNYAYGTL
:: . :. ::. .: . ::.. : .:.: .. :..:: . .::.::.:..
CCDS85 GYYK--DKLFDQRELRFE---IGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSV
180 190 200 210 220 230
130 140 150 160 170 180
pF1KE6 GCPPL-IPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNY
: . ::::. . .:..: .: :: . ...:.. :. .. .: :.
CCDS85 GKEKFQIPPNAELKYELHLKSFEKAKESWE---MNSEEK--------LEQSTIVKERGTV
240 250 260 270
190 200 210 220 230
pF1KE6 LFRQNRFYDAKVRYKRALLLLRRRSA-PPEEQHLVEAAKLPVLLNLSFTYLKLDRPTIAL
:..... .: ..::. . :. .:. :: . ..: .: :::.. .:::. . :.
CCDS85 YFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAI
280 290 300 310 320 330
240 250 260 270 280 290
pF1KE6 CYGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASC
..:: .:..: :.::: :.: : ..... :: . .. . : :. ...: .
CCDS85 ESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQR
340 350 360 370 380 390
300 310 320
pF1KE6 YRDYVDKEKEMWHRMFAPCGDGSTAGES
: . .::... ::
CCDS85 IRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA
400 410 420 430 440 450
>--
initn: 380 init1: 220 opt: 262 Z-score: 333.6 bits: 70.5 E(32554): 2.9e-12
Smith-Waterman score: 262; 39.3% identity (68.9% similar) in 122 aa overlap (25-142:18-137)
10 20 30 40 50
pF1KE6 MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISG--DRGVLKDVIREGAG-DLVAPDASV
: .. .::: :.:::: . :::.: .. :
CCDS85 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LVKYSGYLEHMD-RPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNY
.:.:.:.: .: :::. :: . ::. .. . .... .:. ::. .. ::.:
CCDS85 FVHYTGWL--LDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 AYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATERE
:::. : :: ::::.:..::.::..:
CCDS85 AYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVE
120 130 140 150 160 170
327 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:20:18 2016 done: Tue Nov 8 12:20:18 2016
Total Scan time: 2.250 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]